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AiPing Zhang,Zhang Lin Peng,Xian Wen Gu 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.2
Multi-granularity linguistic information has been studied by researchers in many disciplines, in which the scale of linguistic term sets is usually restricted in domain [0, 1]. In this paper, we consider the multiple attribute group decision making (MAGDM) problems, in which the evaluation of each alternative with respect to each attribute is provided by several experts of the corresponding field. In order to convey the preferences of different experts exactly and to describe the characteristics of different attributes, linguistic term sets with different granularities and different scales have been proposed to express their evaluation values. Moreover, the performance values given by the experts take the form of modified proportional 2-tuples. In this process, the modified proportional 2-tuple, its comparative rules as well as several aggregation operators have been proposed. A new method has been proposed to achieve a basic modified linguistic term set (BMLTS) and a transformation function has been defined to make the performance values uniform. An example is given to illustrate the applicability and flexibility of the method.
Hao Zhang,Jing Sun,Xianting Liu,Chuan Hong,Yuanbo Zhu,Aiping Liu,Siqi Li,Huiyuan Guo,Fazheng Ren 한국미생물학회 2013 The journal of microbiology Vol.51 No.6
Lactobacillus paracasei subsp. paracasei LC01 (LC01) can tolerate intestinal stresses and has antioxidant activity. To evaluate the effect of the bacterium on human intestinal microflora,a randomized, double-blind, placebo-controlled human trial was carried out. Fifty-two healthy adult volunteers were randomized equally to two groups. One group consumed 12% (wt/vol) skimmed milk supplemented with 1010 CFU of LC01 each day for the 4-week treatment period,and then consumed placebo in the next treatment period,separated by a 2-week washout. The other group followed the reverse order. Group-specific real-time PCR and biochemical analyses was used to determine the intestinal bacterial composition of fecal samples collected at the end of every period, and the concentration of short-chain fatty acids and ammonia. A significant inhibition in fecal Escherichia coli and increase in Lactobacillus, Bifidobacterium, and Roseburia intestinalis were observed after consumption of LC01. Acetic acid and butyric acid were significantly higher in the probiotic stage and fecal ammonia was significantly lower. The results indicated a modulation effect of LC01 on the intestinal microflora of young adults, suggesting a beneficial effect on bowel health. LC01 may have potential value as a probiotic.
Xianwen Gu,Aiping Zhang 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.10
The coordinated development of industrialization, informatization, urbanization and agricultural modernization is one of the important concerns in today's China. This paper constructs a set of 4 categories and 16 indicators of evaluation system to measure the development level of industrialization, informatization, urbanization and agricultural modernization of 31 provinces, municipalities and autonomous regions in China. Based on this, provincial coupling level and coordinated development level of four modernizations are calculated by the coupling degree model and the coordinated development degree model. It discovers that the coupling degree and the coordinated development degree of the whole nation and east, central and west China have a significant rise between 2003 and 2012. In general, the coordinated development level of east China is high and that of central and west China is low. By dividing coordination level of all provinces, it discovers that the number of uncoordinated development provinces is decreasing and that of coordinated development provinces is increasing. And eastern provinces are in a leading position.
Xie Tao,Zhang Wei,Chen Chengjie,Wang Xiaoshuang,Zhang Jing,Luan Aiping,He Yehua 한국원예학회 2023 Horticulture, Environment, and Biotechnology Vol.64 No.6
Somatic embryogenesis (SE) is a key regeneration process in plant. AcSERK1 is a gene specifi cally expressed in the early stage of SE in pineapple ( Ananas comosus ), suggesting that the promoter of SERK1 might contain specifi c cis acting element regulating SE. To identify embryonic cell-specifi c element in the SERK1 promoter, a series of binary plant transformation vectors with GUS (β-glucuronidase) reporter gene were systematically analyzed by transient gene expression system in wild-type and transgenic pineapple embryogenic callus. Histochemical and quantitative GUS assays demonstrated that the activity of the AcSERK1 upstream regulatory sequence lacking − 921 to -911 or -910 to -880 was signifi cantly reduced in the embryonic callus of the pineapple, and these two regions were needed for the embryonic cell-specifi c. Besides, a promoter lacking − 943 to -922 was shown to signifi cantly increase GUS activity in embryogenic callus, suggesting repressive elements exist in this region. Our data of stable transformation assays confi rmed again the 5’ upstream regulatory sequence (-921 to -880) of the AcSERK1 gene is an essential functional region. Our fi ndings lay the basis for better understanding of the molecular mechanisms of AcSERK1 gene in the regulation in early stage of SE.
Cloning and Characterization of the IgA Fc Receptor from Swine
( Yumei Chen ),( Yunchao Liu ),( Gaiping Zhang ),( Hua Feng ),( Pengchao Ji ),( Guoqiang Wang ),( Chang Liu ),( Yapeng Song ),( Yunfang Su ),( Songlin Qiao ),( Aiping Wang ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.12
The myeloid-specific IgA Fc receptor (FcαR) is a cell surface molecule on immunocytes that provides a fundamental connection between humoral and cellular immunity. In this study, the full-length cDNA sequence of swine FcαRI (swFcαRI) was isolated and characterized and found to contain a 792-base-pair open reading frame, encoding a 264-amino-acid transmembrane glycoprotein with a predicted molecular mass of 29.4 kDa. The swFcαRI shares high amino acid sequence homology (>50%) with its counterparts from cattle, seal, and horse. Rosetting analysis confirmed that COS-7 cells transfected with an swFcαRI expression plasmid was able to combine with chicken erythrocytes sensitized with porcine IgA, but not IgG.
Surface oxidation and thermoelectric properties of indium-doped tin telluride nanowires
Li, Zhen,Xu, Enzhi,Losovyj, Yaroslav,Li, Nan,Chen, Aiping,Swartzentruber, Brian,Sinitsyn, Nikolai,Yoo, Jinkyoung,Jia, Quanxi,Zhang, Shixiong The Royal Society of Chemistry 2017 Nanoscale Vol.9 No.35
<P>The recent discovery of excellent thermoelectric properties and topological surface states in SnTe-based compounds has attracted extensive attention in various research areas. Indium doped SnTe is of particular interest because, depending on the doping level, it can either generate resonant states in the bulk valence band leading to enhanced thermoelectric properties, or induce superconductivity that coexists with topological states. Here we report on the vapor deposition of In-doped SnTe nanowires and the study of their surface oxidation and thermoelectric properties. The nanowire growth is assisted by Au catalysts, and their morphologies vary as a function of substrate position and temperature. Transmission electron microscopy characterization reveals the formation of an amorphous surface in single crystalline nanowires. X-ray photoelectron spectroscopy studies suggest that the nanowire surface is composed of In2O3, SnO2, Te and TeO2which can be readily removed by argon ion sputtering. Exposure of the cleaned nanowires to atmosphere leads to rapid oxidation of the surface within only one minute. Characterization of electrical conductivity<I>σ</I>, thermopower<I>S</I>, and thermal conductivity<I>κ</I>was performed on the same In-doped nanowire which shows suppressed<I>σ</I>and<I>κ</I>but enhanced<I>S</I>yielding an improved thermoelectric figure of merit<I>ZT</I>compared to the undoped SnTe.</P>
Ashraf, Zaman,Alamgeer,,Rasool, Raqiqatur,Hassan, Mubashir,Ahsan, Haseeb,Afzal, Samina,Afzal, Khurram,Cho, Hongsik,Kim, Song Ja,Zhang, Ge,Lu, Aiping MDPI 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.12
<P>Dexibuprofen–antioxidant conjugates were synthesized with the aim to reduce its gastrointestinal effects. The esters analogs of dexibuprofen <B>5a</B>–<B>c</B> were obtained by reacting its –COOH group with chloroacetyl derivatives <B>3a</B>–<B>c</B>. The in vitro hydrolysis data confirmed that synthesized prodrugs <B>5a</B>–<B>c</B> were stable in stomach while undergo significant hydrolysis in 80% human plasma and thus release free dexibuprofen. The minimum reversion was observed at pH 1.2 suggesting that prodrugs are less irritating to stomach than dexibuprofen. The anti-inflammatory activity of <B>5c</B> (<I>p</I> < 0.001) is more significant than the parent dexibuprofen. The prodrug <B>5c</B> produced maximum inhibition (42.06%) of paw-edema against egg-albumin induced inflammation in mice. Anti-pyretic effects in mice indicated that prodrugs <B>5a</B> and <B>5b</B> showed significant inhibition of pyrexia (<I>p</I> < 0.001). The analgesic activity of <B>5a</B> is more pronounced compared to other synthesized prodrugs. The mean percent inhibition indicated that the prodrug <B>5a</B> was more active in decreasing the number of writhes induced by acetic acid than standard dexibuprofen. The ulcerogenic activity results assured that synthesized prodrugs produce less gastrointestinal adverse effects than dexibuprofen. The ex vivo antiplatelet aggregation activity results also confirmed that synthesized prodrugs are less irritant to gastrointestinal mucosa than the parent dexibuprofen. Molecular docking analysis showed that the prodrugs <B>5a</B>–<B>c</B> interacts with the residues present in active binding sites of target protein. The stability of drug–target complexes is verified by molecular dynamic simulation study. It exhibited that synthesized prodrugs formed stable complexes with the COX-2 protein thus support our wet lab results. It is therefore concluded that the synthesized prodrugs have promising pharmacological activities with reduced gastrointestinal adverse effects than the parent drug.</P>