Ultrasound findings in peliosis hepatis

Dong Yi,Wang Wen-Ping,Lim Adrian,이원재,Dirk-Andre Clevert,Michael Höpfner,Andrea Tannapfel,Christoph Frank Dietrich 대한초음파의학회 2021 ULTRASONOGRAPHY Vol.40 No.4

Purpose: The aim of this study was to retrospectively evaluate contrast-enhanced ultrasound (CEUS) findings in patients with peliosis hepatis (PH). Methods: A retrospective analysis was conducted of CEUS features in 24 patients with histopathologically confirmed PH (11 men and 13 women; mean age, 32.4±7.1 years; range, 28 to 41 years). All lesions were histologically proven, either by core needle biopsy (n=10) or by hepatic surgery (n=14). Results: The mean size was 36.8±12.4 mm (range, 10 to 80 mm). On B-mode ultrasonography (BMUS), all PH lesions were heterogeneously hypoechoic, with well-defined margins but irregular shapes. No mass effect was observed. During the arterial phase of CEUS, all lesions displayed mild heterogeneous hyperenhancement (83.3%, 20/24) or isoenhancement (16.7%, 4/24). Furthermore, 87.5% of the PH lesions showed mild washout after 1 minute in the portal venous phase (30-120 seconds) and mild washout in the late phase (>120 seconds). Conclusion: The lack of a mass effect on BMUS, mild heterogeneous arterial hyperenhancement, and washout in the very late portal venous phase (after 1 minute) on CEUS are characteristic of PH. Although it is a histological diagnosis, PH should be considered in the differential diagnosis when the clinical context does not favor a malignancy or infection. Purpose: The aim of this study was to retrospectively evaluate contrast-enhanced ultrasound (CEUS) findings in patients with peliosis hepatis (PH).Methods: A retrospective analysis was conducted of CEUS features in 24 patients with histopathologically confirmed PH (11 men and 13 women; mean age, 32.4±7.1 years; range, 28 to 41 years). All lesions were histologically proven, either by core needle biopsy (n=10) or by hepatic surgery (n=14).Results: The mean size was 36.8±12.4 mm (range, 10 to 80 mm). On B-mode ultrasonography (BMUS), all PH lesions were heterogeneously hypoechoic, with well-defined margins but irregular shapes. No mass effect was observed. During the arterial phase of CEUS, all lesions displayed mild heterogeneous hyperenhancement (83.3%, 20/24) or isoenhancement (16.7%, 4/24). Furthermore, 87.5% of the PH lesions showed mild washout after 1 minute in the portal venous phase (30-120 seconds) and mild washout in the late phase (>120 seconds).Conclusion: The lack of a mass effect on BMUS, mild heterogeneous arterial hyperenhancement, and washout in the very late portal venous phase (after 1 minute) on CEUS are characteristic of PH. Although it is a histological diagnosis, PH should be considered in the differential diagnosis when the clinical context does not favor a malignancy or infection.

Groundwater supply under land subsidence constrains in the Nobi Plain

Adrian H. Gallardo,Atsunao Marui,Shinji Takeda,Fumio Okuda 한국지질과학협의회 2009 Geosciences Journal Vol.13 No.2

Groundwater overdraft resulted in land subsidence throughout the Nobi Plain, central Japan. To cope with the growing water demand in the region, a numerical model was used to determine the maximum withdrawal capacity of two confined aquifers without causing undesirable consequences. Results were validated against field data and by analytical solutions. The analysis focused in Aburashima, a site expected to experience a rapid development in the forthcoming years. Calculations showed the water availability in the upper aquifer is limited. Moreover, seasonal fluctuations in heads reduce its extraction capacity up to 44%. In contrast, storage is substantially higher in the deep aquifer. Larger quantities and lower extraction costs make this layer a more reliable source for water supply. Findings from this study will be used by authorities to update the current legislation on groundwater abstraction. Nevertheless, it is argued that to achieve a long-term sustainability, policies should not limit solely to control regulations but also to economical strategies and the expansion of the infrastructure system.

A 6-Point TACS Score Predicts In-Hospital Mortality Following Total Anterior Circulation Stroke

Adrian D Wood,Nicholas D Gollop,Joao H Bettencourt-Silva,Allan B Clark,Anthony K Metcalf,Kristian M Bowles,Marcus D Flather,John F Potter,Phyo Kyaw Myinta 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.4

Background and Purpose Little is known about the factors associated with in-hospital mortality following total anterior circulation stroke (TACS). We examined the characteristics and comorbidity data for TACS patients in relation to in-hospital mortality with the aim of developing a simple clinical rule for predicting the acute mortality outcome in TACS. Methods A routine data registry of one regional hospital in the UK was analyzed. The sub¬jects were 2,971 stroke patients with TACS (82% ischemic; median age=81 years, interquar¬tile age range=74–86 years) admitted between 1996 and 2012. Uni- and multivariate regres¬sion models were used to estimate in-hospital mortality odds ratios for the study covariates. A 6-point TACS scoring system was developed from regression analyses to predict in-hospi¬tal mortality as the outcome. Results Factors associated with in-hospital mortality of TACS were male sex [adjusted odds ratio (AOR)=1.19], age (AOR=4.96 for ≥85 years vs. <65 years), hemorrhagic subtype (AOR=1.70), nonlateralization (AOR=1.75), prestroke disability (AOR=1.73 for moderate disability vs. no symptoms), and congestive heart failure (CHF) (AOR=1.61). Risk stratifica¬tion using the 6-point TACS Score [T=type (hemorrhage=1 point) and territory (nonlateral¬ization=1 point), A=age (65–84 years=1 point, ≥85 years=2 points), C=CHF (if present=1 point), S=status before stroke (prestroke modified Rankin Scale score of 4 or 5=1 point)] reli-ably predicted a mortality outcome: score=0, 29.4% mortality; score=1, 46.2% mortality [negative predictive value (NPV)=70.6%, positive predictive value (PPV)=46.2%]; score=2, 64.1% mortality (NPV=70.6, PPV=64.1%); score=3, 73.7% mortality (NPV=70.6%, PPV=73.7%); and score=4 or 5, 81.2% mortality (NPV=70.6%, PPV=81.2%). Conclusions We have identified the key determinants of in-hospital mortality following TACS and derived a 6-point TACS Score that can be used to predict the prognosis of particular patients.

Functional Magnetic Resonance Imaging of Motor Cortex Activation in Schizophrenia

이효종,Adrian Preda,Judith M. Ford,Daniel H. Mathalon,David B. Keator,Theo G.M. van Erp,Jessica A. Turner,Steven G. Potkin 대한의학회 2015 Journal of Korean medical science Vol.30 No.5

Previous fMRI studies of sensorimotor activation in schizophrenia have found in some cases hypoactivity, no difference, or hyperactivity when comparing patients with controls; similar disagreement exists in studies of motor laterality. In this multi-site fMRI study of a sensorimotor task in individuals with chronic schizophrenia and matched healthy controls, subjects responded with a right-handed finger press to an irregularly flashing visual checker board. The analysis includes eighty-five subjects with schizophrenia diagnosed according to the DSM-IV criteria and eighty-six healthy volunteer subjects. Voxel-wise statistical parametric maps were generated for each subject and analyzed for group differences; the percent Blood Oxygenation Level Dependent (BOLD) signal changes were also calculated over predefined anatomical regions of the primary sensory, motor, and visual cortex. Both healthy controls and subjects with schizophrenia showed strongly lateralized activation in the precentral gyrus, inferior frontal gyrus, and inferior parietal lobule, and strong activations in the visual cortex. There were no significant differences between subjects with schizophrenia and controls in this multi-site fMRI study. Furthermore, there was no significant difference in laterality found between healthy controls and schizophrenic subjects. This study can serve as a baseline measurement of schizophrenic dysfunction in other cognitive processes.

On the Overhead Bridge

CHO SE-H?I,Adrian Buzo(번역자) The Academy of Korean Studies 1980 Korea Journal Vol.20 No.10

장애인 교육·복지실태 국제비교 연구

정동영,Ashman, Adrian F.,Kimm, Christina H.,Opp, Gu¨nter,Kim, Sung Ae,Ochiai, Toshiro 국립특수교육원 1998 연구보고서 Vol.- No.5

금속연료 소듐냉각고속로 중대사고 고유안전특성 SAS4A/SASSYS-1 코드 전산해석

강석훈(S.H. Kang),Adrian Tentner 한국전산유체공학회 2021 한국전산유체공학회지 Vol.26 No.1

The inherent safety characteristics of the metal fuel core sodium-cooled fast reactor (SFR) are investigated using the SAS4A metal fuel version code, originally developed for the analysis of postulated severe accidents in oxide fuel SFR and significantly extended to allow the mechanistic analysis of severe accidents in metallic fuel SFRs. The paper provides an overview of the SAS4A key metal fuel models and the safety characteristics of the metal fuels. The analysis is performed for a postulated unprotected fuel assembly inlet blockage accident in the metal fuel Prototype Gen-IV Sodium Fast Reactor (PGSFR). The evolution of local fuel components during the pre-transient irradiation, molten fuel relocation behavior inside and outside of cladding, and their impacts on reactivity and power history during the transient are numerically analyzed. The favorable characteristics of the metal fuel, significant decreases in reactivity and power due to favorable molten fuel relocation and the fuel thermo-physical property change, are analyzed in the results.

Practical multiple scattering for rough surfaces

Lee, Joo Ho,Jarabo, Adrian,Jeon, Daniel S.,Gutierrez, Diego,Kim, Min H. Association for Computing Machinery 2019 ACM transactions on graphics Vol.37 No.6

Should Male Circumcision be Advocated for Genital Cancer Prevention?

Morris, Brian J.,Mindel, Adrian,Tobian, Aaron A.R.,Hankins, Catherine A.,Gray, Ronald H.,Bailey, Robert C.,Bosch, Xavier,Wodak, Alex D. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

The recent policy statement by the Cancer Council of Australia on infant circumcision and cancer prevention and the announcement that the quadrivalent human papillomavirus (HPV) vaccine will be made available for boys in Australia prompted us to provide an assessment of genital cancer prevention. While HPV vaccination of boys should help reduce anal cancer in homosexual men and cervical cancer in women, it will have little or no impact on penile or prostate cancer. Male circumcision can reduce cervical, penile and possibly prostate cancer. Promotion of both HPV vaccination and male circumcision will synergistically maximize genital cancer prevention.

Effects of background noise on generating coherent packets of hairpin vortices (10 pages)

Kim, K.,Sung, H.J.,Adrian, R.J. AMERICAN INSTITUTE OF PHYSICS 2008 Physics of fluids Vol.20 No.10