Mantle cell lymphoma relapsed after autologous stem cell transplantation: a single-center experience

Aaron Wu,Solomon A. Graf,Nicholas Burwick,Jonathan E. Grim,Zhao Ming Dong,Robert E. Richard,Thomas R. Chauncey 대한혈액학회 2020 Blood Research Vol.55 No.1

BackgroundAutologous stem cell transplantation (autoSCT) can extend remission of mantle cell lym-phoma (MCL), but the management of subsequent relapse is challenging.MethodsWe examined consecutive patients with MCL who underwent autoSCT at Veterans Affairs Puget Sound Health Care System between 2009 and 2017 (N=37).ResultsTen patients experienced disease progression after autoSCT and were included in this analysis. Median progression free survival after autoSCT was 1.8 years (range, 0.3‒7.1) and median overall survival after progression was only 0.7 years (range, 0.1 to not reached). The 3 patients who survived more than 1 year after progression were treated with ibrutinib.ConclusionOur findings suggest that ibrutinib can achieve relatively prolonged control of MCL pro-gressing after autoSCT.

AKARI AND SPINNING DUST: INVESTIGATING THE NATURE OF ANOMALOUS MICROWAVE EMISSION VIA INFRARED SURVEYS

AARON C. BELL,TAKASHI ONAKA,YASUO DOI,ITSUKI SAKON,Fumihiko Usui,DAISUKE ISHIHARA,HIDEHIRO KANEDA,MARTIN GIARD,RONIN WU,RYOU OHSAWA,TAMAMI MORI-ITO,MARK HAMMONDS,이호규,Itsuki Sakon 한국천문학회 2017 天文學論叢 Vol.32 No.1

Our understanding of dust emission, interaction, and evolution, is evolving. In recent years, electric dipole emission by spinning dust has been suggested to explain the anomalous microwave excess (AME), appearing between 10 and 90 Ghz. The observed frequencies suggest that spinning grains should be on the order of 10nm in size, hinting at polycyclic aromatic hydrocarbon molecules (PAHs). We present data from the AKARI/Infrared Camera (IRC) due to its high sensitivity to the PAH bands. By inspecting the IRC data for a few AME regions, we find a preliminary indication that regions well-fitted by a spinning-dust model have a higher 9~$\mu$m than 18~$\mu$m intensity vs. non-spinning-dust regions. Ongoing efforts to improve the analysis by using DustEM and including data from the AKARI Far Infrared Surveyor (FIS), IRAS, and Planck High Frequency Instrument (HFI) are described.

Genetic analysis of genetic basis of a physiological disorder ‘‘straighthead’’ in rice (Oryza sativa L.)

Dianxing Wu,Xiaobai Li,Wengui Yan,Hesham Agrama,Aaron Jackson,Melissa Jia,Limeng Jia,Karen Moldenhauer,Fernando Correa 한국유전학회 2016 Genes & Genomics Vol.38 No.5

Straighthead is a physiological disorder in rice that causes yield losses and is a serious threat to rice production worldwide. Identification of QTL conferring resistance will help develop resistant cultivars for straighthead control. We conducted linkage mapping to identify QTL involved with straighthead. The study was based on a F2 population developed from a cross between ‘Zhe733(resistant)/R312(susceptible)’. Using phenotypic data of F2 plants and their F2:3 families, two major QTL, qSTH-2 and qSTH-8, were identified using bulked segregant analysis, explaining 11.1 and 28.1 % of the phenotypic variation on chromosome 2 and 8, respectively. The qSTH-2 for straighthead resistance was identified by linkage mapping. qSTH-2 was situated near a QTL ‘‘AsS’’ responsible for arsenic accumulation. Straighthead is frequently observed on land where As has accumulated. The result suggests a kind of internal connection between qSTH-2 and AsS. Additionally, the QTL qSTH-8 was located close to HD5 related with heading date. The close location may be associated with the observation of early heading among straighthead resistant varieties. These findings should be useful for further genetic study of straighthead.

Safety and Health Perceptions in Work-related Transport Activities in Ghanaian Industries

Atombo, Charles,Wu, Chaozhong,Tettehfio, Emmanuel O.,Nyamuame, Godwin Y.,Agbo, Aaron A. Occupational Safety and Health Research Institute 2017 Safety and health at work Vol.8 No.2

Background: With the recent rapid industrialization, occupational safety and health (OSH) has become an important issue in all industrial and human activities. However, incidents of injuries and fatality rates in the Ghanaian industry sector continue to increase. Despite this increase, there is no evidence regarding the element of OSH management in transport activities in Ghanaian industries. Thus, this study aims to examine the perceptions regarding the importance of safety and health in work-related transport activities in Ghanaian industries. Methods: A survey data collection technique was used to gather information on best safety practices over a 5-month period. We randomly selected 298 respondents from industries to answer structured questionnaires. The respondents included drivers, transport managers, and safety engineers. Standard multiple regression model and Pearson product-movement correlation were used to performed the analysis. Results: The result shows that for interventions to improve safety and health, concentration has been on drivers' safety practice with less attention to safe driving environments and vehicle usage. Additionally, the respondents are aware of the importance of OSH in transport activities, but the level of integration does not measure up to the standard to reduce operational accidents and injuries. Finally, strong commitment to changing unsafe practices at all levels of operations appears to be the effective way to improve safety situations. Conclusion: OSH culture is not fully complied in industries transport activities. This study, therefore, supports the use of safety seminars and training sessions for industry workers responsible for transport operations for better integration of safety standards.

Silicon-Based Telecommunication Avalanche Photodetectors

Wei Shu Wu,Aaron R. Hawkings,John E. Bowers 한국통신학회 1997 OPTOELECTRONICS & COMMUNICATIONS CONFERENCE Vol.2 No.1

Safety and Health Perceptions in Work-related Transport Activities in Ghanaian Industries

Charles Atombo,Chaozhong Wu,Emmanuel O. Tettehfio,Godwin Y. Nyamuame,Aaron A. Agbo 한국산업안전보건공단 산업안전보건연구원 2017 Safety and health at work Vol.8 No.2

Background With the recent rapid industrialization, occupational safety and health (OSH) has become an important issue in all industrial and human activities. However, incidents of injuries and fatality rates in the Ghanaian industry sector continue to increase. Despite this increase, there is no evidence regarding the element of OSH management in transport activities in Ghanaian industries. Thus, this study aims to examine the perceptions regarding the importance of safety and health in work-related transport activities in Ghanaian industries. Methods A survey data collection technique was used to gather information on best safety practices over a 5-month period. We randomly selected 298 respondents from industries to answer structured questionnaires. The respondents included drivers, transport managers, and safety engineers. Standard multiple regression model and Pearson product–movement correlation were used to performed the analysis. Results The result shows that for interventions to improve safety and health, concentration has been on drivers’ safety practice with less attention to safe driving environments and vehicle usage. Additionally, the respondents are aware of the importance of OSH in transport activities, but the level of integration does not measure up to the standard to reduce operational accidents and injuries. Finally, strong commitment to changing unsafe practices at all levels of operations appears to be the effective way to improve safety situations. Conclusion OSH culture is not fully complied in industries transport activities. This study, therefore, supports the use of safety seminars and training sessions for industry workers responsible for transport operations for better integration of safety standards.

Computed tomographic analysis of maxillary sinus anatomy relevant to sinus lift procedures in edentulous ridges in Taiwanese patients

Yu, Shun-Jen,Lee, Yi-Hao,Lin, Ching-Ping,Wu, Aaron Yu-Jen Korean Academy of Periodontology 2019 Journal of Periodontal & Implant Science Vol.49 No.4

Purpose: To analyze the maxillary sinus anatomy over edentulous ridges in the bilateral posterior maxillary area in Taiwanese patients using cone-beam computed tomography (CBCT). Methods: In total, 101 anatomical sites from 61 patients, including 32 premolar and 69 molar regions, were analyzed using CBCT. Measurements were made of the width and height of edentulous ridges, the thickness of the lateral wall of the maxillary sinus, and the presence of a sinus septum and the posterior superior alveolar artery (PSAA). A statistical analysis of the measurements was performed, and correlations among the measurements were assessed. Results: The average ridge width was $10.26{\pm}3.16mm$, with a significantly greater ridge width in the second molar region than in the premolar region. The mean residual ridge height was $8.55{\pm}4.09mm$, and ridge height showed an opposite trend from ridge width for the premolar and molar regions. A sinus septum was present at 5.9% of the sites, and the PSAA was observed in 24.5%. The average thickness of the lateral wall of the maxillary sinus was $2.08{\pm}0.94mm$, with no significant difference between the tooth position and lateral wall thickness. Conclusions: This study presents the anatomical features of the maxillary sinus, which should be considered in sinus lift procedures for implant placement, in the Taiwanese population. The use of CBCT is recommended to avoid intraoperative complications.

Computed tomographic analysis of maxillary sinus anatomy relevant to sinus lift procedures in edentulous ridges in Taiwanese patients

Shun-Jen Yu,Yi-Hao Lee,Ching-Ping Lin,Aaron Yu-Jen Wu 대한치주과학회 2019 Journal of Periodontal & Implant Science Vol.49 No.4

Purpose: To analyze the maxillary sinus anatomy over edentulous ridges in the bilateral posterior maxillary area in Taiwanese patients using cone-beam computed tomography (CBCT). Methods: In total, 101 anatomical sites from 61 patients, including 32 premolar and 69 molar regions, were analyzed using CBCT. Measurements were made of the width and height of edentulous ridges, the thickness of the lateral wall of the maxillary sinus, and the presence of a sinus septum and the posterior superior alveolar artery (PSAA). A statistical analysis of the measurements was performed, and correlations among the measurements were assessed. Results: The average ridge width was 10.26±3.16 mm, with a significantly greater ridge width in the second molar region than in the premolar region. The mean residual ridge height was 8.55±4.09 mm, and ridge height showed an opposite trend from ridge width for the premolar and molar regions. A sinus septum was present at 5.9% of the sites, and the PSAA was observed in 24.5%. The average thickness of the lateral wall of the maxillary sinus was 2.08±0.94 mm, with no significant difference between the tooth position and lateral wall thickness. Conclusions: This study presents the anatomical features of the maxillary sinus, which should be considered in sinus lift procedures for implant placement, in the Taiwanese population. The use of CBCT is recommended to avoid intraoperative complications.