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      • Testing Whether New Is Better Than Used of Specified Age Using Moments Inequalities

        Ahmad, Ibrahim A.,Al-Wasel, Ibrahim A. The Korean Reliability Society 2002 International Journal of Reliability and Applicati Vol.3 No.1

        The class of “new better than used of a specified age” is a large and practical class of life distributions. Its properties, applicability, and testing was discussed by Hollander, Park and Proschan (1986). Their test, while remaining the yardstick for this class, suffers from weak efficiency and weak power, especially for specified ages below the average age. Thus, it is beneficial to have an alternative testing procedure that would work better for early ages and still work well for later ages. This is exactly the subject of the current note. The test developed here is also simpler than that of Hollander, et. al. (1986).

      • KCI등재

        NOx removal efficiency and N2 selectivity during selective catalytic reduction processes over Al2O3 supported highly cross-linked polyethylene catalysts

        Ahmad M. Abu-Jrai,Ala’a H. Al-Muhtaseb,Jehad A. Yamin,Khalid A. Ibrahim,Omar A. Al-Khashman,Mouath A. Al-Shaweesh,Muhannad A. Hararah,Umer Rashid,Mohammad Ahmad,Gavin M. Walker 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

        The performance of a highly cross-linked polyethylene catalyst supported on alumina for low temperature selective catalytic reduction of NOx by unburned hydrocarbons (HCs) existing in an exhaust gas was examined at different engine conditions with the addition of exhaust-gas recirculation. The HXPE catalyst was shown to exhibit good NOx reduction activity at low temperatures (100–250℃) where the only reductant was the unburned HC, which was already present in the exhaust flow. The maximum NOx reduction of approximately 52% was achieved at a temperature of 150℃. HXPE demonstrated very good selectivity toward N2 in the majority of tested conditions ( 80%).

      • KCI등재

        Differential antioxidative and biochemical responses to aluminium stress in Brassica juncea cultivars

        Javed Ahmad,Mohd Affan Baig,Arlene Asthana Ali,Asma Abdulkareem Al‑Huqail,Mohamed Mohamed Ibrahim,Mohammad I rfan Q ureshi 한국원예학회 2018 Horticulture, Environment, and Biotechnology Vol.59 No.5

        Aluminium (Al) toxicity in acidic soils limits crop production worldwide. We evaluated eleven genotypes of Brassica juncea (Mustard) under Al stress on basis of their growth and shortlisted two best among them for further comparative analysis. Our objective was to elucidate individual and differential oxidative damage and defence response elicited by Al treatment in selected mustard genotypes, ‘Pusa Tarak’ and ‘Pusa Vijay’. Thirty-day-old plants of both genotypes were subjected to Al stress for a period of 24 h and 72 h. Concentration of superoxides was visible much higher in leaves of ‘Pusa Vijay’ both at 24 h and 72 h, also confirmed by oxidative stress marker thiobarbituric acid reactive substances (TBARS). The activities of the enzymatic antioxidants superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione reductase (GR), glutathione S-transferase (GST), and catalase (CAT) were significantly higher in ‘Pusa Tarak’ compared to control and ‘Pusa Vijay’ at both time stages. Levels of non-enzymatic antioxidants glutathiones and ascorbates were already higher in ‘Pusa Vijay’; however, Al treatment increased their levels in both genotypes with non-significant changes on inter-genotypes basis. More and significant decline by Al in chlorophylls was observed in ‘Pusa Vijay’. Interestingly, increase in proline content by Al was much prominent in ‘Pusa Tarak’ compared to ‘Pusa Vijay’. The in vitro antioxidant capacity estimation of mustard genotypes, evaluated by measuring 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and hydroxyl radical scavenging (HRSA) activities proved that extract of ‘Pusa Tarak’ can detoxify more radicals than ‘Pusa Vijay’. We conclude that ‘Pusa Tarak’ can upregulate cellular antioxidants and osmoregulation, and quench more radicals compared to ‘Pusa Vijay’. The results will contribute for selection of better Brassica genus to be grown in Al rich acidic soils, and help in designing strategies for crop breeding and cultivation.

      • SCOPUSKCI등재
      • Physical Activity and Cancer Prevention: Awareness and Meeting the Recommendations among Adult Saudis

        Amin, Tarek Tawfik,Al-Hammam, Abudllah Mohammed,AlMulhim, Nasser Abdullah,Al-Hayan, Mohammed Ibrahim,Al-Mulhim, Mona Mohammed,Al-Mosabeh, Modhahir Jawad,Al-Subaie, Mohammed Ali,Al-Hmmad, Qassem Ahmed Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

        Background: There is a scarcity of information about the proportion of the adult Saudi population that meet the recommended guidelines of physical activity (PA) to reduce cancer risk. Moreover, their awareness about the role of PA in cancer prevention is unclear. Objectives: This cross-sectional study aimed at estimating the proportion of adult Saudis meeting the PA guidelines, specifically those recommended by American Cancer Society (ACS) for cancer prevention, and to assess the public awareness about the role of PA in cancer prevention. Materials and Methods: Using a multistage sampling method, 2,127 adult Saudis of both genders were recruited from 6 urban and 4 rural primary health care centers in Al Hassa, Saudi Arabia. Participants were personally interviewed to gather information about their sociodemographic characteristics, searching activity about PA and cancer, and the time spent in leisure time PA (moderate and vigorous)/week using the Global Physical Activity Questionnaire with show cards. Finally, items about the role of PA in cancer risk reduction were inquired. Results: Of the included participants, 11.6% met the recommendations for cancer prevention (${\geq}45$ minutes of moderate-vigorous PA activity/${\geq}5$ days/week or 225 minutes/week). Multivariate regression showed that being male (AOR=1.49, CI=1.09-2.06), <20 years of age (AOR=3.11, CI=2.03-4.76), and unemployed (AOR=2.22, CI=1.57-3.18) were significant predictors for meeting PA recommendations for cancer prevention. Only 11.4% of the sample indicated correctly the frequency and duration of PA required for an average adult to be physically active and while >70% of them indicated the role of PA in prevention of hypertension, coronary heart disease and lowering elevated blood cholesterol, only 18.6% and 21.7% correctly mentioned the role of PA in reducing colon and breast cancer risk, respectively. Poor knowledge was found among those with less than college education and aged ${\geq}50$ years. The level of knowledge was significantly positively correlated with total leisure time PA of the participants. Conclusions: A minority of adult Saudis in Al Hassa was aware about the role of PA in cancer prevention and engaged in sufficient LTPA for cancer risk reduction benefits, highlighting the need for public health actions to include policies and programs that address factors deterring their participation in LTPA and increasing their awareness with remedies to manage the prevalent misconceptions.

      • Effects of Tobacco Smoking on the Dorsum of the Tongue and Buccal Epithelium

        Al Shammari, Abdullah Faraj,AL Ibrahim, Ibrahim Khalil,Alaauldeen, Amjad Ibrahim,Merza, Randa Fouad,Ahmed, Hussain Gadelkarim Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.10

        Objective: The aim of this study was to assess the effects of tobacco smoking on the dorsum of the tongue and buccal epithelium. Methodology: This case control cross-sectional study was conducted with 174 smoking and non-smoking volunteers living in the city of Hail, Northern KSA. Cytological Materials were obtained from buccal mucosa and dorsum of the tongue, and assessed using cytopathological methods. Results: In buccal smears, cytological atypia was observed in 17 out of 101 (16.8%) smoker cases but only 3/73(4.1%) of the controls. For cytological atypia in buccal and tongue smears, the adjusted odd ratio (OR) and the 95% confidence interval (CI) were found to be 4.7 (1.3-16.8), P < 0.016)) and 4.3 (0.93- 20.2), P <0.06)), respectively, in the two sites. Conclusion: Tobacco smoking is a major risk factor for occurrence of cytological atypia, which might subsequently develop into oral precancerous and cancerous lesions. Oral exfoliative cytology is an easy and cheap non-invasive procedure which appears highly suitable for screening populations at risk of developing oral cancer.

      • Hepatitis C Virus Prevalence and Genotyping among Hepatocellular Carcinoma Patients in Baghdad

        Al-Kubaisy, Waqar Abd Al Qahar,Obaid, Kadhim Jawad,Noor, Nor Aini Mohd,Ibrahim, Nik Shamsidah Binti Nik,Al-Azawi, Ahmed Albu-Kareem Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

        Hepatocellular carcinoma (HCC) is the third most common cause for cancer death in the world, now being especially linked to chronic hepatitis C virus (HCV) infection. This case-control study consisting of 65 HCC patients and 82 patients with other malignant tumours as controls was conducted to determine the association of HCV markers with HCC. Serum of each participant was obtained for detection of HCV Ab and RNA by DNA enzyme immunoassay (DEIA). Twenty six per cent (26.0%) of HCC patients had positive anti-HCV which was significantly greater than the control group (p=0.001). HCC patients significantly have a risk of exposure to HCV infection almost 3 times than the control group (OR=2.87, 95% C.I=1.1-7). Anti-HCV seropositive rate was significantly (p=0.03) higher among old age HCC patients and increases with age. Males with HCC significantly showed to have more than 9 times risk of exposure to HCV infection (OR=9.375, 95 % CI=1.299-67.647) than females. HCV-RNA seropositive rate was (70.8%) significantly higher among HCC patients compared to (22.2%) the control group (p=0.019). The most prevalent genotype (as a single or mixed pattern of infection) was HCV-1b. This study detected a significantly higher HCV seropositive rate of antibodies and RNA in HCC patients.

      • KCI등재

        Genetic and clinical characteristics of pediatric patients with familial hemophagocytic lymphohistiocytosis

        Ali Al Ahmari,Osama Alsmadi,Atia Sheereen,Tanziel Elamin,Amal Jabr,Lina El-Baik,Safa Alhissi,Bandar Al Saud,Moheeb Al-Awwami,Ibrahim Al Fawaz,Mouhab Ayas,Khawar Siddiqui,Abbas Hawwari 대한혈액학회 2021 Blood Research Vol.56 No.2

        Background Our study was designed to investigate the frequencies and distributions of familial hemophagocytic lymphohistiocytosis (FHL) associated genes in Saudi patients. Methods FHL associated gene screening was performed on 87 Saudi patients who were diagnosed with hemophagocytic lymphohistiocytosis (HLH) between 1995 and 2014. The clinical and biochemical profiles were also retrospectively captured and analyzed. Results Homozygous mutations and mono-allelic variants were identified in 66 (75.9%) and 3 (3.5%) of the study participants, respectively. STXBP2 was the most frequently mutated gene (36% of patients) and mutations in STXBP2 and STX11 accounted for 58% of all FHL cases and demonstrated a specific geographical pattern. Patients in the FHL group presented at a significantly younger age than those belonging to the unknown-genetics group (median, 3.9 vs. 9.4 mo; P=0.005). The presenting clinical features were similar among the various genetic groups and the 5-year overall survival (OS) was 55.4% with a 5.6 year median follow-up. Patients with PRF1 mutations had a significantly poorer 5-year OS (21.4%, P =0.008) and patients undergoing hematopoietic stem cell transplant (72.4%) had a significantly better 5-year OS (66.5% vs. 0%, P =0.001). Conclusion Our study revealed the predominance of the STXBP2 mutations in Saudi patients with FHL. A genetic diagnosis was possible in 80% of the cohort and our data showed improved survival in FHL patients who underwent hematopoietic stem cell transplant.

      • KCI등재

        Gum Arabic Supplementation Suppresses Colonic Fibrosis After Acute Colitis by Reducing Transforming Growth Factor β1 Expression

        Amna Al-Araimi,Ishraq A. Al Kindi,Asma Bani Oraba,Amira AlKharusi,Badreldin H. Ali,Shadia Al Sinawi,Ibrahim Al-Haddabi,Fahad Zadjali 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.12

        Ulcerative colitis is a chronic inflammation of the colonic mucosa. Gum Arabic (GA) has been reported to exert anti-inflammatory and antifibrotic activity. This study aimed to evaluate the effect of GA on disease activity in an experimental model of colitis. Dextran sodium sulfate (DSS) was used to induce colitis in C57BL/6 mice and the animals were then switched to normal drinking water to monitor recovery. Mice received 140 g/L GA before (pre-GA group) or after (post-GA group) induction of colitis. Disease activity and recovery were assessed by changes in body weight, disease activity index (DAI), and histological assessment. Gene expression of proinflammatory, anti-inflammatory, and fibrotic markers was measured in colonic tissues. Mice in the pre-GA group showed an increase in body weight, with no differences in DAI scores, during the recovery phase and had lower histological colitis scores than mice in the post-GA group, which showed higher DAI and histological scores during the recovery phase. During the recovery phase, mice in the pre-GA group showed increased expression of proinflammatory markers, while gene expression of the fibrotic markers, transforming growth factor β1 (TGFβ1) and procollagen I, was reduced. The reduced fibrotic marker expression was associated with reduced collagen staining and increased epithelial cell proliferation. Administration of GA had protective and alleviative effects on the severity of DSS-induced colitis, with a reduction in colonic fibrosis and TGFβ1 expression. These data warrant further in vitro and in vivo investigations on the effect of GA on fibroblast activity.

      • KCI등재

        Effect of propolis supplementation and breed on growth performance, immunity, blood parameters and cecal microbiota in growing rabbits

        Al-Homidan Ibrahim,Fathi Moataz,Abdelsalam Magdy,Ebeid Tarek,Abou-Emera Osama,Mostafa Mohamed,El-Razik Mohamed Abd,Shehab-El-Deen Mohamed 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.10

        Objective: The present study was conducted to investigate the potential effects of dietary supplemented propolis in two growing rabbit breeds on growth performance, immune response, blood parameters, carcass characteristics, and cecal microflora composition. Methods: A total of 90 growing rabbits aged 6 weeks from two breeds (V-line and Jabali) were randomly allocated to 3 dietary propolis experimental treatments. The experimental treatments consisted of a 2×3 factorial arrangement with two rabbit breeds and three levels of dietary propolis supplementation (0, 250 mg/kg, and 500 mg/kg). Each sub-treatment has 15 rabbits. The experimental period lasted six weeks. Results: There were no significant differences in growth performance and carcass characteristics due to propolis administration. Propolis supplementation at a high level significantly increased (linear; p<0.05) cellular-mediated immunity compared with the unsupplemented group. Furthermore, the rabbits receiving propolis exhibited a significant increase (linear and quadratic; p<0.03) in IgM immunoglobulins compared to the control. The current study provides further evidence that the dietary inclusion of propolis can significantly reduce pathogenic bacterial colonization in growing rabbits. The total count of microflora, E. coli, and Salmonella spp. was significantly lower (linear; p<0.01) in supplemented rabbit groups compared to the control group according to the microbiological analysis of cecal digesta. Based on breed effect, the results indicated that Jabali rabbits (local) performed better than V-line rabbits (foreign) in the majority of the studied traits. Conclusion: Dietary propolis is promising for further investigation into improving intestinal health and enhancing immunity in growing rabbits. Objective: The present study was conducted to investigate the potential effects of dietary supplemented propolis in two growing rabbit breeds on growth performance, immune response, blood parameters, carcass characteristics, and cecal microflora composition.Methods: A total of 90 growing rabbits aged 6 weeks from two breeds (V-line and Jabali) were randomly allocated to 3 dietary propolis experimental treatments. The experimental treatments consisted of a 2×3 factorial arrangement with two rabbit breeds and three levels of dietary propolis supplementation (0, 250 mg/kg, and 500 mg/kg). Each sub-treatment has 15 rabbits. The experimental period lasted six weeks.Results: There were no significant differences in growth performance and carcass characteristics due to propolis administration. Propolis supplementation at a high level significantly increased (linear; p<0.05) cellular-mediated immunity compared with the unsupplemented group. Furthermore, the rabbits receiving propolis exhibited a significant increase (linear and quadratic; p<0.03) in IgM immunoglobulins compared to the control. The current study provides further evidence that the dietary inclusion of propolis can significantly reduce pathogenic bacterial colonization in growing rabbits. The total count of microflora, E. coli, and Salmonella spp. was significantly lower (linear; p<0.01) in supplemented rabbit groups compared to the control group according to the microbiological analysis of cecal digesta. Based on breed effect, the results indicated that Jabali rabbits (local) performed better than V-line rabbits (foreign) in the majority of the studied traits.Conclusion: Dietary propolis is promising for further investigation into improving intestinal health and enhancing immunity in growing rabbits.

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