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Kubelka-Munk 모델을 이용한 피부 분광반사율 연구
조아라 ( A Ra Cho ),김수지 ( Su Ji Kim ),이준배 ( Jun Bae Lee ),심건영 ( Geon Young Sim ),백민 ( Min Back ),조은슬 ( Eun Seul Cho ),장지희 ( Ji Hui Jang ),장은선 ( Eunseon Jang ),김연준 ( Youn Joon Kim ),유권종 ( Kweon Jong Yoo ) 대한화장품학회 2016 대한화장품학회지 Vol.42 No.1
빛은 피부에서 개개인마다 상이한 반사, 흡수 및 산란 등의 광학적 거동을 보여준다. 특히, 피부에서 빛의 반사는 분광반사율이라는 물리량 측정을 통해 개인의 피부 밝기지표로 널리 활용되어 왔다. 따라서 피부에서 빛의 반사 거동 연구는 개인 맞춤형 화장품, 특히 메이크업 제품 개발에 있어 좀 더 효율적인 처방 개선에 기여하거나 새로운 평가법에 활용될 수 있다. 본 연구에서는 Kubelka-Munk 모델을 이용하여 개인의 피부 특성에 따른 빛의 분광반사율 거동에 대해 다각적인 분석을 수행하였다. 또한, 상기 모델과 기존에 알려진 문헌 정보를 이용하여 개인의 피부 분광반사율에 영향을 줄 수 있는 피부 두께 및 헤모글로빈 등의 다양한 파라미터들에 대한 기여도 분석을 수행하였다. 이를 통해, 일반적인 여성의 피부에서의 분광반사율 이론치를 계산하였고, 분광반사율 실측을 통해 이론치와 실측치 간의 유사성을 확인하였다. Kubelka-Munk 모델을 이용한 피부 분광반사율 연구는 향후 새로운 개인 맞춤형 메이크업 화장품 개발에 유용하게 이용될 수 있을 것으로 사료된다. Light shows various optical behaviors such as reflection, absorption, and scattering on skin for individuals. In particular, reflection of light from the skin has been widely used as the brightness index of the skin of individuals through the measurement of the physical quantity of spectral reflectance. Therefore, the study of light behavior on skin would be useful for the preparation of new evaluation method in the development stage of make-up products. In this study, multi-dimensional analysis for spectral reflectance behavior of light on individual skin was performed using Kubelka-Munk model. Also, we analyzed the contribution of skin parameters such as skin thickness and hemoglobin, which could affect the spectral reflectance, using above model and literature information. Base on this, we calculated the theoretical reflectance of normal women for visual light, which showed good agreement with the measured reflectance. Our study of light propagation in skin based on Kubelka-Munk model provides useful insight for the development of personalized cosmetic in the near future.
산림수확 시뮬레이터 HARVEST 응용에 의한 벌채지 공간배치 사례연구
송정은 ( Jung Wun Song ),장광민 ( Kwang Min Jang ),한희 ( Hee Han ),설아라 ( A Ra Seol ),정우담 ( Woo Dam Chung ),정주상 ( Joo Sang Chung ) 한국산림과학회 2012 한국산림과학회지 Vol.101 No.1
In this study, we used HARVEST, a timber management strategy assessment tool, to evaluate alternative forest planning strategies on spatial pattern of cutting blocks. We applied the tool to the Gwangreung Experimental Forest (GEF) as a case study. The harvest schedules developed for GEF using a linear programming model was used to assess spatial patterns of cutting blocks under different management constraints. The results show that the allowable maximum harvest size largely affects the number, size, and distribution of cutting blocks. We also found that spatial dispersion methods and adjacency constraints could be used as an effective means to control spatial allocation of cutting blocks in order to meet certain forest ecosystem management goals.
Assessing Vascular Changes Associated with Healthy Aging using 7T Magnetic Resonance Angiography
So-Ra Jang,Chan-A Park,Kyung-Jin Lee,Yeong-Bae Lee,Hang-Keun Kim,Chang-Ki Kang 한국자기학회 2018 Journal of Magnetics Vol.23 No.1
Aging is known to produce changes in the cerebral vasculature and circulation. We aimed to quantitatively assess age-related changes in the morphology of small perforating vessels, lenticulostriate arteries (LSAs). LSA images were acquired using ultra-high field 7-Tesla magnetic resonance imaging (7T MRI) from 24 young healthy volunteers (young group: YG) and 25 old healthy volunteers (old group: OG). Vessel-related factors such as curvature and tortuosity were analyzed using two-dimensional images. Our quantitative results demonstrated a fewer in their branches and a significantly more pronounced curvature in the OG compared to the YG. These findings were further confirmed qualitatively using image analysis. Our study findings show that MR angiography utilizing ultra-high field MRI can provide high-resolution images that can identify morphological characteristics of small perforating vessels. Based on these features, it is possible to document ageinduced changes in cerebral small vessels.
Hong, A-Ra,Kim, Jungyoon,Kim, Su Yeon,Kim, Seong-Il,Lee, Kwangyeol,Jang, Ho Seong Optical Society of America 2015 Optics letters Vol.40 No.21
<P>The core/shell-structured upconversion nanophosphors (UCNPs) and Cd-free CuInS<sub>2</sub>/ZnS quantum dots (QDs) were synthesized via coprecipitation and hot-injection methods, respectively, and they were applied to near infrared (NIR) photodetectors. The 관-NaYF<sub>4</sub>:Yb,Er/관-NaYF<sub>4</sub> UCNPs emitted intense visible light peaking at 522, 542, and 656 nm via H<sub>11/2</sub>2, S4<sub>3/2</sub>, and F<sub>9/2</sub>4???I<sub>15/2</sub>4 transitions under excitation with 980 nm NIR light. The core/shell UCNPs showed 6.4 times higher emission intensity than core UCNPs. Charge carriers can be generated from CuInS<sub>2</sub>/ZnS QDs in the QD-UCNP mixture due to their broad absorption in the visible spectral region shorter than 600 nm. The photodetector devices were fabricated by spin-coating CuInS<sub>2</sub>/ZnS QDs on a SiO<sub>2</sub>/Si substrate with patterned gold electrodes followed by spin-coating UCNPs on the QD layer. The fabricated QD-UCNP-bilayer-based device showed a drastically increased photocurrent (128 관A) compared with the QD-layer-based device under 980 nm NIR light illumination. Additionally, the fabricated device showed stable ON-OFF switching properties against on and off NIR light.</P>
빌로바라이드가 글루타메이트에 의한 신경독성에 미치는 영향
김소라(So Ra Kim),장영표(Young Pyo Jang),성상현(Sang Hyun Sung),이흠숙(Heum Sook Lee),문애리(A Ree Moon),김영중(Young Choong Kim) 대한약학회 1997 약학회지 Vol.41 No.1
The neurotoxicity induced by L-glutamate in primary cultures of rat cortical cells could be attenuated by sesquiterpene constituent of Ginkgo biloba leaves, bilobalide. At the concentration of 100 nM, Bilobalide elevated the combined levels of reduced/oxidized glutathione in rat cortical cells exposed to 100mcM glutamate. Furthermore, bilobalide promoted a reduction in superoxide dismutase activity in glutamate-treated cells. Finally, bilobalide markedly inhibited the production of malondialdehyde. a measure of lipid peroxidation, in glutamate-treated rat cortical cells.
플라이오메트릭 운동이 BMI 23 이상 성인 남녀의 심폐기능에 미치는 영향
권근아(Geun-A Kwon),윤형근(Hyoung-Gun Yun),이리라(Ri-Ra Yi),임나윤(Na-Yoon Lim),장영호(Young-Ho Jang),정선민(Sun-Min Jung),이건철(Keon-Cheol Lee),배원식(Won-Sik Bae) 대한심장호흡물리치료학회 2015 대한심장호흡물리치료학회지 Vol.3 No.1
Purpose : The purpose of this study was to investigate for the effect of rope-jumping and plyometric exercise on the cardiopulmonary function to overweight people. Method : This study was performed on overweight 18 males and 15 females subjects. They were divided in to 3 groups(11 subjects per 1 group) using random sampling and rope-jumping and plyometric exercise, respectively. In order to compare the difference of VO2max, AT, RER, HRmax before and after applying progressive rope-jumping and plyometric exercise. Cardiopulmonary function was examined using CS-200 ERGO-SPIRO. Results : 1. VO2max, AT, RER, HRmax function before and after exercise in non exercise group A and rope-jumping and plyometric exercise in group C significantly different(p<.05) 2. VO2max, AT, RER, HRmax function before and after exericse in non exercise group A and rope-jumping exercise in group B significantly different(p<.05) 3. VO2max, AT, RER, HRmax function before and after exericse in rope-jumping exercise in group B and rope-jumping and plyometric exercise group C non-significantly different(p<.05) Conclusion : Rope-jumping exercise and plyometric exercise is improve exercise in cardiopulmonary function that combined areobic exercise and plyometric exercise is more effective increasing cardiopulmonary function.
Isolation and Culture Properties of a Thermophilic Agarase-Producing Strain, Microbulbifer sp. SD-1
Kim, Do-Kyun,Jang, Yu-Ri,Kim, Kyoung-Hoon,Lee, Mi-Nan,Kim, A-Ra,Jo, Eun-Ji,Byun, Tae-Hwan,Jeong, Eun-Tak,Kwon, Hyun-Ju,Kim, Byung-Woo,Lee, Eun-Woo The Korean Society of Fisheries and Aquatic Scienc 2011 Fisheries and Aquatic Sciences Vol.14 No.3
An agar-degrading enzyme-producing strain was isolated from seawater. The isolate was identified as Microbulbifer sp. SD-1 by 16S rRNA sequencing analysis. The optimal pH and temperature for growth were 6.0 and $30^{\circ}C$, respectively, and growth was possible at pH 9.0 and $60^{\circ}C$. The isolate required 5% NaCl for optimal growth and showed 45% growth activity without NaCl. Agar concentrations of 0-0.4% in the medium did not affect growth. Thin-layer chromatography analysis revealed that this strain could degrade agar into a monosaccharide and oligosaccharide, which may have industrial applications.
Facile method for the synthesis of gold nanoparticles using an ion coater
Lee, Seung Han,Jung, Hyun Kyu,Kim, Tae Cheol,Kim, Chang Hee,Shin, Chang Hwan,Yoon, Tae-Sik,Hong, A.-Ra,Jang, Ho Seong,Kim, Dong Hun Elsevier 2018 APPLIED SURFACE SCIENCE - Vol.434 No.-
<P><B>Abstract</B></P> <P>Herein we report a metal nanoparticle synthesis method based on a physical vapor deposition process instead of the conventional wet process of chemical reactions in liquids. A narrow size distribution of synthesized gold nanoparticles was obtained using an ion coater on glycerin at low vapor pressure. The nanoparticle size could be modulated by controlling the sputtering conditions especially the discharge current. Due to the formation of gold nanoparticles, a surface plasmon resonance peak appeared at ∼530 nm in the absorption spectrum. The surface plasmon resonance peak exhibited red-shift with increasing size of the gold nanoparticles. Our results provide a simple, environmental friendly method for the synthesis of metal nanoparticles by combine low-cost deposition apparatus and a liquid medium, which is free from toxic reagents.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Gold nanoparticles were synthesized on glycerin using ion coater. </LI> <LI> The nanoparticle size could be modulated by controlling the sputtering conditions. </LI> <LI> Surface plasmon resonance peaks were observed in the gold colloidal solutions. </LI> </UL> </P>