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      • SCOPUSKCI등재

        성상신경절 차단을 이용한 구강내 편평태선의 통증 치료

        한영진(Young Jin Han),최 훈(Huhn Choe),심요택(Yo T 대한통증학회 1997 The Korean Journal of Pain Vol.10 No.1

        Common oral lesions of lichen planus (LP) are bilateral lace-like white patches in the buccal and lingual mucosae. Oral LP of chronic erosive and ulcerative forms develop carcinomas among approxi- mately 1% of affected patients. A 64 year old male patient suffering from LP with early verrucous carcinoma on lips, tongue, and hard palate for approximately 8 years was refered to the pain clinic from department of dermatology. He complained of severe pain (VAS 9.5) on lips, oral cavity and left of the face. For 18 consecutive days we performed stellate ganglion blocks (SGB) with 6 ml on his left side of face. Patients pain decreased to (VAS 3.0) after 18 SGB. After a total of 31 SGB patient was discharged free of pain. pain recurred (VAS 3.5) 22 days after discharge. We then performed SGB, twice weekly and pain was effectively relieved after total 54 SGB. But patient needed to take oral analgesics due to nocturnal pain.

      • SCOPUSKCI등재

        Morphine 과 Buprenorphine 의 지속적 정주에 의한 술후 통증 억제효과의 비교

        백선기(Sun Ki Baek),소상윤(Sang Yoon So),한영진(Yo 대한통증학회 1994 The Korean Journal of Pain Vol.7 No.1

        N/A Morphine, a p-receptor agonist, produces strong analgesic effect with some side effects such as nausea, vomiting, urinary retension, somnolence, and respiratory depression. Buprenorphine also provides strong analgesic effects, and hemodynamic changes after continuous infusion of morphine, or buprenorphine-ketorolac combination in gynecologic patients. Analgesic effect was assessed by visual analogue scale(VAS) and Prince Henry scale(PHS). Morphine group, ini- tial 2 mg of bolus morphine was followed by 48 mg/96 ml of continuous infusion. Buprenorphine group, initial 0.1 mg of buprenorphine was followed up with infusion by 2.3 mg/100 ml. Half dose of both initial bolus and maintenance buprenorphine with ketorolac 15mg for bolus and 60mg for maintenance were infused in buprenorphine-ketorolac combination group. No signifi- cant hemodynamic changes were seen in any of the groups. VAS significantly decreased after 15 minutes of infusion in all three groups, and was significantly lower in morphine group than the other 2 groups, after 60 minutes. PHS was decreased significantly 15 minutes after infusion in the morphine group, and after 60 minutes in two other groups. The incidence of side effects were similar between morphine and buprenorphine groups, but significantly reduced in buprenorphine-ketorolac combination group. We concluded that buprenorphine could be an alternative to morphine for postoperative pain, and smaller dose of buprenorphine could be used if it is combined with ketorolac with less side effects.

      • SCOPUSKCI등재

        Fentanyl 이 Epidural Bupivacaine 의 작용에 미치는 영향

        최훈,한영진,장영익,심요택 대한마취과학회 1989 Korean Journal of Anesthesiology Vol.22 No.3

        The effects of epidural fentanyl in combination with 0.5% bupivacaine were observed in randomized 60 patients undergoing lower abdominal surgery. The time of onset, segmental spread and duration of analgesia, changes in arterial blood pressure and heart rate and the incidence of side effects were observed after epidural injection of the drugs. The patients were divided into three groups; Group I: 0.9% NaCl 2 ml combined with 20ml of 0.5% bupivacaine, Group II: 0.9% NaCl 1ml and fentanyl 50ug (1 ml) combined with 20 ml of 0.5% bupivacaine, Group III: fentanyl 100 ug (2ml) combined with 20 ml of 0.5% bupivacaine. The results were as follows. 1) The time of onset was significantly short in group III (P $lt; 0.01) 2) The level of sensory blockade 30 minutes after epidural injection in group III was 2-3 segments higher than group I. 3) The mean duration of analgesia was significantly long in group III compared to groups I and II (P$lt;0.01). 4) The cardiovascular changes were not significantly different among the patients of the three groups. 6) The side effects including mild hypotension, nausea and vomiting, voiding difficulty, itching and backache were not significantly different in the occurrence among the patients of the three groups. From the above results, it is suggested that fentanyl 100ug combined with 0.5% bupivacaine for epidural anesthesia has some benefits in its onset, spread and postoperative analgesia.

      • SCOPUSKCI등재

        상복부 수술후 진통을 위한 경막외 약물주입에 관한 연구

        최현규,최훈,한영진,심요택 대한마취과학회 1990 Korean Journal of Anesthesiology Vol.23 No.6

        Among various mehtods for postoperative pain management, epidural narcotics is one of the most prevalent techniques used by anesthesiologists. Although it is a highly effective analgesia, epidural morhpine has disadvantages such as delayed onset, nausea, vomiting, pruritus, urinary retension and even life-threatening respiratory depression. To search for a more effective analgesic mehtod with minimum side effects, we studied the effects of morphine, bupivacaine and a combination of each durg with different dosages in patients undergoing upper abdominal surgery. Hemodynamic changes, duration of analgesia, and side effects were compared. The results suggested that the combination of 2 mg of morphine and 0.125% of bupivacaine is the most effective method with minimum side effects for postoperative pain.

      • 수술중 수혈에 관한 임상적 고찰

        송희선,김태요,한영진 전북대학교 의과학연구소 1979 全北醫大論文集 Vol.3 No.-

        654 transfusions out of 2051 anesthesias during 3 years from April 1, 1975 to March 31, 1978 were analyzed. The results were: 1.The average amount of transfused blood was 2.4 pints per one patient. 2.There was no significant differences between the amount of transfused blood per one patient in elective surgery and that of emergency surgery. 3.The frequency of performing both operations and transfusions was the greatest in General Surgery patients, while the average amount of transfused blood per one patient was the greatest in the Chest Surgery patients. 4.The most frequently used blood group was type A blood, while type AB blood was the most difficult to supply. 5.The preoperative hemoglobin levels of the patients were within the range of 10-14 gm%.

      • SCOPUSKCI등재

        Ketamine 이 자라 심장기능에 미치는 영향

        최훈,송희선,김태요,한영진 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.4

        Effects of ketamine on the cardiovascular system of tcrtoises was obsered in this study. Ketamine elevated blood preasure and increased contractile performance and heart rate of the tortoise's auricle. The hypertensive effect of ketamine was abolished by treatment with hexametbonium or Regitine, while increment of heart rate due to ketamine was not affected by treatment of hexamethonjum, Inderal, or Regitine. In vitro experiments, ketamine increased contractile performance and heart rate of the auricle. These effects of ketamine were not affected by Regitine, Inderal,cocaine, or reserpine pretreatment. Synergism of ketamine and norepinephrine was also observed. Low bath temperature did not influence the effects of ketamine but high bath temperature inhibited the effects of the drug. In the electrically stimulated preparations, field stimulation did not affect the chronotropic and inotropic effects of ketamir, but direct stimulation abolished these effects of the drug. From the above results, it is possible to say that ketamine probably has dual actions on the cardiovascular system of tortoises, i, e., hypertensive action due to stimulation of sympathetic nervous system, and chronotropic and inotropic setions due to direct stimulation of cardiac muscle.

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