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- 저자 : 편정아 ( Jung A Pyun ) (검색결과 5 건)
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반복되는 두통으로 내원한 소아청소년 환자의 임상양상과 뇌파검사
편정은(Jung Eun Pyun),변정혜(Jung Hye Byeon),은소희(So Hee Eun),김건하(Gun Ha Kim),은백린(Baik Lin Eun) 대한소아신경학회 2014 대한소아신경학회지 Vol.22 No.3
Purpose: We compared clinical findings of headaches to find out important characteristics for the differential diagnosis of headaches. We tried to find out specific electroencephalogram (EEG) findings according to the types of primary headache and the relationship between clinical characteristics and EEG findings by analyzing EEGs of migraine. Method: We conducted a retrospective analysis by reviewing medical records of 275 patients who visited the Department of Pediatrics of Korea University Guro Hospital from November 2010 to October 2013. The headaches were classified according to the International Classification of Headache Disorders-II (ICHD- II). EEG was analyzed in relation to the type of headache. Results: 245 (89.1%) were primary headache patients, and 30 (10.9%) were secondary headache patients.There were no differences in the frequencies of abnormal EEG findings according to the type of primary headache (P=0.855), and epileptiform discharge was most common abnormal EEG finding in the primary headache. Comparing the patients with epileptiform discharges to the patients with normal EEG finding in migraine, the patients showing epileptiform discharge were younger (P=0.035) and presented with occipital and atypical (i.e., not pulsating or pressing) headache (P=0.005). Conclusion: History and physical examination are the most important in the diagnosis of headache in children. There were no significant differences in EEG findings among the different types of primary headaches.However, we could find a relationship between clinical features of the migraine and its epileptiform discharge, so more studies correlating EEG findings to clinical features are needed in the future.
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퀴어 청소년문학의 터전을 마련하다 -초기 퀴어 청소년소설의 의의와 한계 검토-
편정인(Jung In Pyun) 한국문화연구학회 2020 문화연구 Vol.8 No.1
본고는 퀴어 문학의 활성화와 페미니즘 리부트가 이루어진 2010년대 중후반 이전, 퀴어 청소년문학의 황무지에서도 그 저변을 마련한 초기 작품들의 등장 배경과 퀴어적 욕망을 확인하고, 그 의의와한계를 살펴보고자 한다. 한국의 퀴어 청소년문학은 동성애자 인권운동, 대중문화 속 동성애 콘텐츠의 양적 증가, 청소년문학 장르의 활성화라는 사회적 흐름 속에서 전개되어 왔다. 동성애를 다룬 초기의 장편 청소년소설은 모두 가족에 대한 커밍아웃을 통과제의적 사건으로 다루고 있으며, 가족 구성원의 반응을 단일화시켜 이야기를 단순화하는 전략을 택했지만, 갈등 봉합의 양상은 작품마다 크게 달랐다. 청소년소설에서 동성애적 성적 실천은 플라토닉적 사랑부터 11살 차이의 성인 남성과의 첫 경험까지, 넓은 스펙트럼으로 구현되었다. 퀴어 청소년의 주체적인 목소리를 드러내고, 정체성의 선언을 주체성의 사유로 변환하며 깊은 함의를 이끌어내는 작품도 눈에 띄었다. 다만 남성들의 동성애를 다루는 과정에서 여성의 모습이 조롱 되거나, 여성의 판타지에 기대어 재현되면서, 또 다른 폭력이 야기되는 문제점은 개선되어야 할 요소로 보인다. This paper attempts to identify the queer desires of early works that provided the foundations of the queer youth literature before the mid and late 2010s period when the activation of queer literature and the feminist reboot, and to examine its significance and limitations. Korean youth novels dealing with homosexuality have been developed in the social flow of the homosexual human rights movement, the quantitative increase of homosexual cultural content, and the activation of the genre of youth literature. The early feature-length youth novels dealing with homosexuality all include a come-out to the family as a rite of passage. They chose a strategy that simplifies the story by unifying the reactions of family members, but the aspect of conflict resolution differed greatly from work to work. Homosexual sexual practice in youth novels ranges from platonic love, to first sex with an adult male. There was also a work that revealed the subjective voice of queer youth, transformed the declaration of identity into an idea of subjectivity, and brought out deep implications. However, in the process of dealing with homosexuality among men, the appearance of women being mocked and the reproduction of women s fantasy causes another violence.
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위장관 ; MMP7, MMP8, MMP9 유전자의 단일염기다형성과 위암 발생 및 림프절 전이와의 연관성 연구
김지혜 ( Ji Hye Kim ),편정아 ( Jung A Pyun ),이광재 ( Kwang Jae Lee ),조성원 ( Sung Won Cho ),곽규범 ( Kyu Bum Kwack ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.5
Background/Aims: Matrix metallopeptidase (MMP) is known to be involved in tumor invasion and metastasis of cancer. This study investigated the association of MMP7 rs11568818, MMP8 rs11225395, MMP9 rs17576 and rs2250889 with gastric cancer (GC) development and lymph node metastasis (LNM). Methods: Samples were obtained from 326 chronic gastritis (CG) and 153 GC patients and genotyped by using the GoldenGate(R) method. Chi-square test was performed to identify the difference of allele distribution between each group (CG vs. GC; CG vs. with LNM GC). The associations of genotype with risk of GC and LNM were estimated by odds ratio and the 95% confidence interval was calculated by logistic regression adjusting for age and sex. Results: The allele and genotype frequencies of MMP7 rs11568818, MMP8 rs11225395, MMP9 rs17576 and rs2250889 were not associated with the development of GC and LNM. Conclusions: In summary, MMP7 rs11568818, MMP8 rs11225395 MMP9 rs17576 and rs2250889 were not associated with the GC development and LNM in Korean population. (Korean J Gastroenterol 2011;58:245-251)
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한국인 위암 발병과 H-RAS 유전자 다형성의 연관성 연구
송희진 ( Hee Jin Song ),편정아 ( Jung A Pyun ),이광재 ( Kwang Jae Lee ),조성원 ( Sung Won Cho ),곽규범 ( Kyu Bum Kwack ) 대한소화기학회 2010 대한소화기학회지 Vol.56 No.2
Background/Aims: Oncogenic RAS gene mutations have been frequently observed in many tumor types, and their associations with various cancers were reported. This study was conducted to evaluate the association between H-RAS T81C polymorphism and gastric cancer development. Methods: H-RAS T81C polymorphism was genotyped in 321 chronic gastritis (ChG) and 151 gastric cancer (GC) patients using GoldenGate(R) Assay kit. Logistic regression analysis adjusted for age and gender was performed to identify the differences of genotype and allele distributions between the each group. Results: All ChG and GC patients were in Hardy-Weinberg equilibrium. When the frequencies of H-RAS T81C genotype in each group were compared, the homozygous type of major allele TT was more frequent in GC group (62.9%) than ChG group (57.3%), while the frequencies of heterozygous type TC and homozygous type of minor allele CC were higher in ChG group than GC group (39.3% vs. 33.8%, 3.4% vs. 3.3%, respectively). In the results of logistic regression analyses adjusted for age and gender, the odds ratios were 0.845 (0.604-1.182), 0.799 (0.556-1.147), 0.741 (0.493-1.114) and 1.094 (0.366-3.270) for allele, codominant, dominant and recessive models, respectively. However, significant difference was not observed between two groups in any models. Conclusions: H-RAS T81C polymorphism was not associated with gastric cancer development in a Korean population. (Korean J Gastroenterol 2010;56:78-82)
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