退行性 膝關節炎에 體質鍼療法이 미치는 영향

채상진,송호섭 대한침구의학회 2004 대한침구의학회지 Vol.31 No.2

Objective : This study was designed to compared the effect of general acupuncture on degenerative arthritis of knee joint with 8 constitution acupuncture by Visual Analogue Scale(VAS). Methods : VAS was used for this research, with the pain indicator of 10 and 0 which represents a pain of first visit and a status of no pain respectively. Two groups, consisting of 40 patients, was randomly allocated for this research. SPSS(Statistic Program for Social Science) 10.0 for window was used for a statistical analysis. Independent T-test and Mann Whitney U test was performed to evaluate the improvement of each group by the treatment number and to compare that of two groups. Results : As a result of the comparison analysis between two groups after 20th treatment, the improvement of subjective symptoms in 8 constitution acupuncture group was shown more effective than that in general acupuncture group, while, After 10th treatment, there was no significant difference between two groups in VAS. Conclusions : It is suggested that the effect of 8 constitution acupunc- ture should be significantly different from that of general acupuncture on degenerative arthritis of knee joint. Further study is needed to confirm the effectiveness of 8 constitution acupuncture.

퇴행성(退行性) 슬관절염(膝關節炎)에 체질침요법(體質鍼療法)이 미치는 영향

채상진,송호섭,Chae, Sang-jin,Song, Ho-sueb 대한침구의학회 2004 대한침구의학회지 Vol.21 No.4

Objective: This study was designed to compared the effect of general acupuncture on degenerative arthritis of knee joint with 8 constitution acupuncture by Visual Analogue Scale(VAS). Methods: VAS was used for this research, with the pain indicator of 10 and 0 which represents a pain of first visit and a status of no pain respectively. Two groups, consisting of 40 patients, was randomly allocated for this research. SPSS(Statistic Program for Social Science) 10.0 for window was used for a statistical analysis. Independent T-test and Mann Whitney U test was performed to evaluate the improvement of each group by the treatment number and to compare that of two groups. Results: As a result of the comparison analysis between two groups after 20th treatment, the improvement of subjective symptoms in 8 constitution acupuncture group was shown more effective than that in general acupuncture group, while, After 10th treatment, there was no significant difference between two groups in VAS. Conclusion: It is suggested that the effect of 8 constitution acupuncture should be significantly different from that of general acupuncture on degenerative arthritis of knee joint. Further study is needed to confirm the effectiveness of 8 constitution acupuncture.

전립선 암세포에 대한 Cobrotoxin의 항암 기전 연구

채상진,송호섭 대한침구의학회 2005 대한침구의학회지 Vol.22 No.3

Cobrotoxin이 전립선 암세포 NF-κB 활성에 미치는 영향

채상진,송호섭 대한침구의학회 2005 대한침구의학회지 Vol.22 No.5

Objectives : The purpose of this study was to investigate the anti-caner effect of cobrotoxin on the prostatic cancer cell line(PC-3). Methods : After the treatment of PC-3 cells with cobrotoxin, we performed fluorescence microscope, MTT assay, Western blotting, Flow cytometry, PAGE electrophoresis and Surface plasmon resonance analysis to identify NF-κB, the change of calcium and NO. Results : 1. The expression of NF-κB was decreased at 1nM and was decreased significantly at 2, 4, 8nM. 2. IκB, NF-κB inhibitor, was decreased significantly at 8nM and p-IκBa, phosphrylation of IκB, was decreased significantly at all concentrations of cobrotoxin. 3. The expressions of p50 and p65 were decreased significantly and dose-dependently at 1, 2, 4, 8nM. 4. The expression of p53 was increased significantly at 1, 2, 4, 8nM. 5. The calcium concentration in cell wasn't changed at 1, 2, 4, 8nM, but was increased dose-dependently at 30, 70, 130, 250nM comparing with lower dose of cobrotoxin. 6. The NO concentration in cell was increased significantly at 1, 2, 4, 8nM. 7. In immunochemical staining, we found that cobrotoxin-immunochemical complex move into intracellular space dose-dependently. Conclusion : These results indicate that cobrotoxin has anti-cancer effects by inducing apoptosis.

요추간판탈출증 환자의 체질침과 체침에 의한 자각적 통증감소 비교

채상진,김남옥,박영철,손성세,Chae, Sang-Jin,Kim, Nam-Ok,Park, Young-Chul,Son, Sung-Se 대한침구의학회 2001 대한침구의학회지 Vol.18 No.3

Objective : The main cause of back pain & sciatica is HNP of L-spine. Recently, 8 Constitution Acupuncture is largely used for it, but the effects isn't announced. So we studied. The perceived pain diminishment is compared with Body acupuncture and 8 Constitution acupuncture. Methods : VAS(Visual analogue scale) was used for this research, with the pain indicator of 10 and 0 which represents a patient admission to a hospital and a status of no pain respectively. Two groups, consisting of Body acupuncture group with 17 persons and 8 Constitution acupuncture group with 12 persons, was randomly allocated for this research. SPSS(Statistical Program for Social Science) for window is used for a statistical analysis, and the independent T-test is performed to gauge the improvement of VAS, in which case, value of P below 0.05 is considered as useful. Results : The result of the VAS of comparison analysis between two groups after 10 days, shows that the improvement of subjective symptoms in Body acupuncture group is more effective than that in 8 Constitution acupuncture group. (independent T-test, P=0.009)

한국어 부정 극성 부사에 대한 연구

채상진 한국화법학회 2000 화법연구 Vol.2 No.-

Negative polarizable adverbs relate to a series of adverbs which have the semantic features of 〔+negative〕 and which are propertied with the agreement relationship of negative factors. They include such vocabularies as mix with precedent negative words like ‘아니(ani)/안(an)’ and ‘못(mot)’ etc. or as have functions to extremely strengthen or maximize the degrees of negation by highlighting agreement with postprecedent negative words like ‘않다(antha)’, ‘없다(eoptta)’, ‘말다(malda)’, ‘아니다(anida)’, ‘못하다(mothada)’, and ‘모르다(moreuda)’ etc. Making a reference to the meanings of adverbs presented in Korean dictionaries and the findings of a questionnaire research. I have come up with the following order in terms of the degree of negative polarizable adverbs: 결코(kyeolko)ㆍ절대로(jeolttaero) 〉전혀(jeonhyeo) 〉도저히(dojeohee) 〉일절(iljeol) 〉지지리(jijiri) 〉도무지(domuji) 〉영(yeong) 〉통(tong) 〉차마(chama) etc. It is usual to put negative polarizable adverbs right after subjects. Yet, as the core factors which the negative polarizable adverbs modify are the negative predicates, they are environmentally propertied by a tendency to be placed close to the cores of the objects they modify. This study can hopefully serve as a basic foundation for other forms of studies on negative polarity words. I think that this study will contribute to future researches for this paper sheds light on the features of their environment, those of their meanings, and their agreement with certain words on the basis of the degree of the negation of the negative polarizable adverbs. And I think that a new grammar category will be established if future studies include other parts of speech or phrases the of negative polarity words.

특발성 말초성 안면신경마비(Bell's Palsy)에 대한 한방치료와 양방병용치료의 비교 고찰

김남옥,채상진,손성세,Kim, Nam-Ok,Chae, Sang-Jin,Son, Sung-Se 대한침구의학회 2001 대한침구의학회지 Vol.18 No.5

Objective : Lately variable oriental-western medicine treatment have been used for Bell's palsy. The purpose of this study is comparison of clinical treatment outcome between oriental medicine group and oriental-western medicine group. Materials and Methods : From 08-01-2000 to 07-30-2001, 30 Bell's palsy out-patients who visited within 5days after onset and treated more than 3weeks at the Department of Acupuncture & Moxibustion, Bundang CHA Oriental Medicine Hospital were selected for two groups. One group(A group) was treated by oriental medicine therapy(Acupunture, Herb, Physical therapy), the other group(B group) was treated by oriental-western medicine therapy(Acupunture, Herb, Physical therapy, Administration of prednison). Two group was composed of 15 patients respectively and measured by HBGS(House-Brackmann Grading System) and DEFS(Detailed Evaluation of Facial Symmetry of Pillsbury and Fisch) at first visit and 3weeks after. Result and Conclusion : A group was marked more higher than B group in treatment outcome. But we discovered that it is not significant differences between two groups.

4번째 동측으로 발생한 벨마비의 치험 1례

김남옥,채상진,손성세,Kim Nam-Ok,Chae Sang-Jin,Son Sung-Se 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.2

Recurrent Bell's palsy is a very rare case and have been reported that shows the incidence to be approximately 10 per cent in the Bell's palsy patents. It is generally accepted that facial paralysis caused by compression of the facial nerve by tumor develops slowly and has an unremitting course, however, reported cases have described the rare association of recurrent facial paralysis and intracranial tumor, and the same recovery rate. Usual symptoms of Bell's palsy include subacute facial palsy, hyperacusis on the affected side, postauricular pain on the affected side, altered sensation of taste, and partial trigeminal distribution hypesthesias. Complete resolution of symptoms is usually seen in 2-3months in $75-85\%$ of cases, with $25-35\%$ showing varying degrees of residual effects. We report a case of 4th ipsilateral recurrent Bell's palsy in a 14-year-old women, which was occurred in every winters. We treated her with acupuncture, moxibustion, herbal medication, carbon and silver spike point, and used House-Brackmnn grading system(HBGS) and the Fisch Detailed Evaluation of Facial Symmetry(DEFS) to assess the degree of paralysis in each part of face.

치창(痔瘡)과 치루(痔漏)에 대한 침구학적(鍼灸學的) 문헌고찰(文獻考察)

송원섭,이병렬,이현,채상진,Song, Won-sub,Lee, Byung-ryul,Lee, Hyun,Chae, Sang-jin 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : The purpose of this study is to arrange the literature about acupuncture therapy on the hemorrhoids and hemorrhoid complicated by anal fistula. Methods : We arrange Huang Di Nei Jing and fifteen kinds of literature about the hemorrhoids and hemorrhoid complicated by anal fistula. Results : 1. The cause of hemorrhoids are overfatigue, overeating, imbalance of stool(const-ipation or diarrhea), uncontrol sexual excess or abstinence, pathgenic factors of wetness, heat, wind, dry, fire, chronical hemorrhoids that has not been treated, and general weakness. 2. Symptom of hemorrhoids is that skin is projected form the nine holes or varicose extension to become hemorrhoid. Hemorrhoids is small nodosity that projected on the anal inter or outer region, and hemorrhoid complicated by anal fistula is pus which comes out form one or some fistula on the anal around inter and outer region. 3. Therapy method of hemorrhoid and hemorrhoid complicated by anal fistula are elimination pathological heat from blood, promote blood flow to remove blood stasis, cold in nature and purge away fire, remove heat form the blood, promote blood flow to remove blood stasis, cold in nature and purge away fire, remove heat from the blood and eliminate dampness, tonify the spleen and replenish Ki, dispel wind and alleviate pain and so forth. Therapy method of hemorrhoid is to give the first consideration to relieve blood: eliminating pathological heat form blood complicated by anal fistula is to tonify the blood first, than after that eliminating pathological heat form blood. About external method are method of fumigation, method of ointment, method of close with medicine, necrotizing method and also operation(injection, bind etc.)was used for treatment. 4. The prescription are Gurgak-hwan, Wypi-hwan, Gunggyi-tang, Jingyochangchul-tang, Jingyobangpung-tang, Mokhyangbinrang-hwan, Ochi-san, Gamihyanso-san, Jojang-hwan, Sinyung-hwan used frequently. 5. food taboo on patient's diet of the hemorrhoid and hemorrhoid complicated by anal fistula are raw grain, cold or dampness food, alcohol, hot food, Singiberis rhizoma recens, Cinnamomi ramulus. 6. Acupuncture therapy on the hemorrhoid and hemorrhoid complicated by anal fistula are, in the first stage eliminating pathological heat form blood and eliminate dampness, and in the long term eliminate dampness, promote and remove meridian energy, remove that form the intestines, dispel channels and collaterals. 7. Acupuncture points at B2, CV1, B58, B36, B56, Sp5, S30, B25, B54, GV1, GV20, L6, B40 used frequently for the acupuncture therapy, and acupuncture point at GV4, GV1, B30, hemorrhoidal point used form moxibustion. Reduction blood at B40 and blue capillary of Sp9 and acupuncture Chungbaek, Ki-gack, Ki-jung, Ki-mun(Dongsh Kihyel) makes the treatment very effective.