중추신경흥분성 식욕억제제 사용의 부작용에 관한 신속 체계적 문헌고찰 : 의존 및 정신병 중심으로

조선진(Sun-Jin Jo),이해국(Hae Kook Lee),박병주(Byung-Joo Park),강훈철(Hoon-Chul Kang),이승엽(Seung-Yup Lee),조중범(Joong-Bum Jo) 한국중독정신의학회 2021 중독정신의학 Vol.25 No.2

Objectives: Although psychostimulants for suppressing appetite have indications for a short-term use, long-term prescriptions are also frequently encountered in clinical practice. The objective of this study was to overview the empirical evidence on the safety of such psychostimulants. Methods : A rapid systematic review was conducted using existing systematic review articles or clinical guidelines developed by adopting systematic review methodology. Results : Four systematic review articles or clinical guidelines were reviewed. Studies on the safety of diethylpropion were all short-term. Six case reports reported psychotic symptoms. Phentermine, phendimetrazine, and diethylpropion have been withdrawn in most countries due to their side effects such as drug abuse and cardiotoxicity. Long-term prescription safety for phentermine or diethylpropion was not addressed in existing clinical guidelines for pharmacological management of adult obesity. Moreover, studies on the efficacy and safety of psychostimulants in the childhood and adolescence obesity management have not been reported yet. Conclusion : The number of studies on the long-term safety of antiobesity psychostimulants prescriptions was too limited to conclude their efficacy and safety for long-term use. Thus, long-term prescriptions of antiobesity psychostimulants should be avoided and closer monitoring is needed even for short-term use of psychostimulants in subjects with mental health risk.

도시 쉼터 남성 노숙인의 우울, 아동기외상, 울분에 따른 중독 특성과의 관련성

정희연(Heeyeon Chung),조선진(Sun-Jin Jo),송후림(Hoo Rim Song),홍민하(Minha Hong),김우정(Woo jung Kim),김영종(Young-Jong Kim),김현수(Hyun-Soo Kim) 한국중독정신의학회 2017 중독정신의학 Vol.21 No.2

Objectives : This study investigated the effects of depression, child trauma, and embitterment on the characteristics on the addiction problems in homeless men. Methods : The subjects were 120 homeless men from a city shelter in Seoul. Questionnaires with socio-demographic and psychiatric content were administered. The instruments included the Patient Health Questionnaire-9, the Childhood Trauma Questionnaire, the Post-Traumatic Embitterment Disorder Self-rating Scale, the Alcohol Use Disorders Identification Test, the Fagerstrom Test for Nicotine Dependence, the Canadian Problem Gambling Index, and the Smartphone Addiction Scale-Short Form. We analyzed the demographic data, score of the above instruments, and frequencies of the addiction problems in homeless men. Results : Depressed subjects displayed significantly higher frequencies in problematic alcohol use, nicotine dependence, and problematic gambling. The child trauma group had significantly higher frequency in problematic alcohol use. The embitterment group exhibited significantly higher frequencies in problematic alcohol use, nicotine dependence, problematic gambling, and problematic smartphone use. Conclusion : The study findings suggest that homeless men with depression, child trauma, embitterment have higher frequencies in addiction problems compared to homeless men without those factors.

일 도시지역 위험음주의 유병률과 관련요인에 관한 연구

조중범(Joong-Bum Jo),이정태(Chung-Tai Lee),권용실(Yong-Sil Kweon),이경욱(Kyoung-Uk Lee),이해국(Hae-Kook Lee),조선진(Sun-Jin Jo),김한오(Hano Kim) 한국중독정신의학회 2011 중독정신의학 Vol.15 No.2

Objective : The aim of this study was to estimate the prevalence of hazardous drinking in a representative community sample of Seoul, Korea and to assess the sociodemographic and psycho-logical factors associated with hazardous drinking. Methods : Sociodemographic data, scores for AUDIT-K and other psycho-logical screening instruments were collected from a sample of 798 individuals from one of the municipal areas of Seoul. Recruitment was done based on a stratified-multistage-cluster sampling. Results : The 12-month prevalence of hazardous drinking was 36.6% (60.5% of males and 18.5% of females). Considering the sample as a whole, multiple logistic regression analysis showed that the risk factors of hazardous drinking were male (adjusted OR=7.96, 95% CI 5.36-11.83), young age (18-29 years old, adjusted OR=3.84, 95% CI 1.81-8.17) and high stress level (adjusted OR=1.72, 95% CI 1.19-2.49). Among males, the widowed/separated/divorced (adjusted OR=5.76, 95% CI 1.17-28.27) and high stress level (adjusted OR=1.68, 95% CI 1.03-2.75) were significant risk factors for hazardous drinking. In the case of females, young age (adjusted OR=6.22, 95% CI 2.04-18.94), high stress level (adjusted OR=2.01, 95% CI 1.12-3.61) and low resilience (adjusted OR=2.15, 95% CI 1.19-3.89) were risk factors for hazardous drinking. Conclusion : The prevalence of hazardous drinking in Seoul in this study was demonstrated to be one of the highest in the world. Our results also suggested that hazardous drinking was further associated with sociodemographic factors than with psychological factors. Preventive measures and intervention pro-grams should be tailored to males, young females and people with stressful life events to reduce the hazardous drinking in the community.

고등학생의 음주관련 지식 및 태도와 음주행위의 영향요인

양수 ( Soo Yang ),송경애 ( Kyeong Yae Sohng ),조선진 ( Sun Jin Jo ) 한국정신간호학회 2003 정신간호학회지 Vol.12 No.4

학교를 기반으로 한 청소년 우울증 인식개선교육 프로그램의 효과

최란(Ran Choi),임현우(Hyeon Woo Yim),조선진(Sun-Jin Jo),방명희(Myeong Hee Bang),지유나(Yu Na Ji),이원철(Won Chul Lee) 한국보건교육건강증진학회 2015 보건교육건강증진학회지 Vol.32 No.1

Objectives: This study was conducted to evaluate the impact of a school-based depression awareness education program on depression knowledge and help-seeking orientation for adolescent. Methods: The students of two high schools were allocated to the intervention (n=221) or control group (n=223) by class unit. The school-based depression awareness education was a 3-session program. The intervention group received pre, post and follow-up tests while the control group received pre and follow up tests after two months. Depression knowledge, attitude to friends’depression, and help-seeking for professional assistance was evaluated at each test. Differences in the two month change between the intervention and control groups were analyzed by t-test or chi-square test. Results: There were positive changes in depression knowledge, response to friends depression, and attitude to professional help-seeking in the post test compared to the pretest among intervention group. Improvement of depression knowledge was greater in the intervention group than in the control group (P=0.011), but there were no significant differences in response to friend’s depression (P=0.268) or help-seeking orientation (P=0.263) after two months. Conclusions: This study revealed the school-based depression awareness education program would improve the level of knowledge on depression. Dissemination and implementation of the program could be suggested.

일개병원의 특수부서 간호사에서 언어폭력, 사회적 지지와 이직의도의 연관성

김현숙(Hyeon-Sook Kim),임현우(Hyeon-Woo Yim),정승희(Seung-Hee Jeong),조선진(Sun-Jin Jo) 대한직업환경의학회 2009 대한직업환경의학회지 Vol.21 No.4

일반인의 우울증 태도에 관한 연구

조현주(Hyun-Ju Cho),임현우(Hyeon-Woo Yim),현명호(Myoung-Ho Hyun),조선진(Sun-Jin Jo),지유나(Yu-Na Ji),전태연(Tae-Youn Jun),방명희(Myeung-Hee Bang) 대한스트레스학회 2008 스트레스硏究 Vol.16 No.3

본 연구는 지역사회 일반인들의 우울증 태도 질문지를 개발하기 위해 구성 개념을 확인하고자 시행하였다. 연구대상은 Y 지역주민 중 층화군집 무작위 추출하여 연구에 동의한 성인 26명이다. 연구진이 참여자를 심층 면담한 축어록을 푼 뒤, 개방 코딩(open coding)을 이용하여 질적인 분석을 실시하였다. 연구결과, 상위 개념으로 우울증 지식과 우울증 태도가 추출되어 두 개념을 분리할 필요성이 제기되었다. 우울증 지식은 우울증 원인, 증상, 치료에 관한 3요인으로 구성되었다. 일반인은 우울증의 증상은 잘 이해하고 있으나 원인은 심리적으로, 치료는 개인의지나 스쳐 지나가는 병으로 인식하는 범주가 많이 나타났다. 우울증 태도는 정서적 거리, 낙인, 가족주의, 개인결함 네 가지 요인으로 구성된다. 일반인은 우울증 환자에 대해 부정적인 정서를 갖고, 편견을 보였으며 환자가 가족인 경우에는 책임감을 느끼는 것으로 나타났다. 본 연구는 일반인의 우울증 태도에 대해 심층 면담한 뒤 그 자료를 질적 분석하여 우울증 태도에 관한 구성 개념을 확인한데 의의가 있다. 본 연구를 통하여, 향후 우울증 예방을 위한 심리교육적 개입에 대한 효과를 검증하는 도구로 발전되고 활용될 수 있으리라 기대한다. This study examined the concepts of depression in oder to develop the depression attitude questionnaire in adult. The participants of study were 26 adults who agreed with our study among the stratified clustered random sampling. Based on ground theory, the data from transcribed interviews were analyzed by using open coding. The result of this study presented the concepts of depression which composed of the knowledge of depression and the attitude of depression. Finally, we were separate the concepts of depression into two questionnaires. The questionnaire for knowledges of depression was composed of the cause, symptoms, and treatment of depression. Most of participants were understood the symptoms of depression well but considered the cause of it to psychological factor, and depression are not genuine disease. The attitudes toward depression were compose of emotional distance, stigma, familism, personal weakness. Participants have a negative emotion to depressive patients and have stigma to them, but they have responsibility to their family member who have depression. We expect that result of the study will be a base upon the development of psychometric tool for depression attitude.

대한민국 군간부에서의 자살 위험성에 대한 위험 요인과 보호 요인

최정민(Jung-Min Choi),변기환(Gihwan Byeon),임현우(Hyeon-Woo Yim),조선진(Sun-Jin Jo),박종익(Jong-Ik Park) 대한신경정신의학회 2021 신경정신의학 Vol.60 No.4

Objectives The aim of this study was to identify risk and protective factors of suicidality among Korean military officers. Methods This study was conducted on 3162 military officers. Data were collected by online survey after obtaining informed consent. Demographic characteristics, depression, anxiety, suicidality, social support, stress, and attitude toward suicide were evaluated using structured instruments and self-report questionnaires. Suicidality was defined as having a suicidal idea, a suicide plan, or attempting suicide. Statistical analysis was performed using logistic regression to investigate associations between potential risk and protective factors and suicidality. Results Depression (odds ratio [OR]=16.313, 95% confidence interval [CI]=10.028-26.539), anxiety (OR=14.377, 95% CI=8.680-23.812), and stress (OR=8.116, 95% CI=4.637-14.207) were positively associated with suicidality. On the other hand, good social networks and an unaccepting attitude toward suicide were negatively associated with suicidality (OR=0.131, 95% CI=0.072-0.240). No significant correlation was observed between living status and suicidality (OR=0.991, 95% CI=0.598-1.642). Conclusion Depression, anxiety, and stress were found to be risk factors of suicidality among Korean military officers. In contrast, good social networks and unaccepting attitudes toward suicide acted as protective factors. Hence, preventive interventions that place focus on risk and protective factors should be developed and implemented to mitigate suicidality.

시범 적용된 응급의학 학생인턴십 프로그램에 대한 참가자들의 경험과 견해; 학생 및 교육자들을 대상으로 한 포커스그룹 연구

최호성 ( Ho Sung Choi ),김영민 ( Young Min Kim ),조선진 ( Sun Jin Jo ),김형민 ( Hyung Min Kim ),위정희 ( Jung Hee Wee ),오주석 ( Joo Suk Oh ),최승필 ( Seung Pil Choi ) 대한응급의학회 2012 대한응급의학회지 Vol.23 No.6

Purpose: The aim of this study was to explore participants` experiences and views of a pilot emergency medicine (EM) sub-internship program. Methods: A pilot 4-week EM sub-internship program involving four academic emergency departments was developed and implemented at the beginning of fourth-year in medical school. Three focus group discussions were separately conducted with ten students, six supervising residents, or four faculty physicians upon completion of the program. Each 60- to 90-minute discussion was recorded, transcribed, and coded by two assessors independently. Contents were thematically analyzed and group interaction examined. Results: The participants identified several strengths of the program, including an opportunity to treat a variety of acute diseases for the first time, an opportunity to apply a symptom- based practice, an opportunity to experience a dynamic workplace, and an opportunity to receive help with careerplanning. Commonly identified weaknesses of the program were placed into three categories: 1) not enough bedside teaching time, 2) the workload of the educators, which impacts program efficiency, and 3) a variety of learning experience among the students. Ideas for improving the program included an announcement about the program inadvance, the development of faculty skills, the development of new content, and a validation of the evaluation methods and institutional support. Conclusion: The EM sub-internship appears to be effective in preparing fourth-year medical students for many of the challenges they will face in the future. However, continuous efforts to strengthen the program are required. These study results will help EM educators develop their own subinternship program.

자살 관련 행동의 과거력이 있는 한국군 장병에서의 스트레스, 우울 증상, 사회적 관계의 연관성

이아영(A-Young Lee),이해우(Hae-Woo Lee),조선진(Sun-Jin Jo),임현우(Hyeon-Woo Yim),장세보(Sae-bo Jang),박종익(Jong-Ik Park) 대한신경정신의학회 2018 신경정신의학 Vol.57 No.4

Objectives This study investigates the relationships between soldiers’ social relations, stress, and depressive symptoms. We also investigated the effect of previous suicide-related behaviors on their correlations. Methods This study was conducted on a total of 1000 soldiers. Study subjects were tested using clinical scales including the Korean Mini-International Neuropsychiatric Interview, the Center for Epidemiological Studies for Depression Scale, the Worker’s Stress Response Inventory and the Lubbens Social Network Scale-6. Sociodemographic characteristics and history of suicide-related behaviors were also examined. In order to investigate the relationships between stress, depression, and social relations in groups with and without a history of suicide-related behavior, one-way correlation analysis was performed. Results Depressive symptoms and stress were positively correlated when sociodemographic factors are controlled, regardless of past history of suicide-related behaviors. Depressive symptoms and social relations showed a weak negative correlation. Furthermore, stress and social relations showed a weak negative correlation. When the stress response was additionally controlled, there was no significant correlation between depressive symptoms and social relations. There was a stronger correlation between the group with a history of suicide-related behavior and the group without suicide - related behavior. Conclusion There was a significant positive correlation between depressive symptoms and stress, and this correlation was greater in patients with a history of suicidal behavior than in those without prior suicidal behavior. In addition, social relations did not directly affect depressive symptoms but was found to mediate stress indirectly.