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정기훈 ( Ki Hun Chung ),이민중 ( Min Jung Lee ),박준수 ( Joon Soo Park ),정현 ( Hyun Chung ) 大韓皮膚科學會 2009 大韓皮膚科學會誌 Vol.47 No.11
Nevus lipomatosus cutaneous superficialis (NLCS) is an idiopathic hamartoma that manifests with ectopic adipose tissue in the dermis. This disease is most frequent located on the lower trunk and gluteal region. Although NLCS can affect any region of a skin, it has not been previously described in the palm in the Korean Dermatologic literature. Herein, we describe a patient with NLCS on the left palm and discuss this rare case. We also review the relevant medical literature. (Korean J Dermatol 2009;47(11):1328~1330)
정기훈 ( Ki Hun Chung ),이민중 ( Min Jung Lee ),고동균 ( Dong Kyun Ko ),박준수 ( Joon Soo Park ),정현 ( Hyun Chung ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.12
Primary cutaneous plasmacytoma is a rare type of cutaneous B-cell lymphoma that arises primarily in the skin, and this is derived from clonally expanded plasma cells with various degrees of maturation and atypia. A 72-year-old man had an asymptomatic, solitary reddish to violaceous nodule on the back for about 4 months. The histologic finding of the skin biopsy specimen demonstrated an infiltration of variably matured plasma cells in the dermis, and these cells showed a monotypic expression of immunoglobulin kappa chains on immunohistochemical staining. Staging investigations excluded any extracutaneous manifestations of the disease. Only a few cases of primary cutaneous plasmacytoma have been published in the Korean dermatologic literature. Herein, we report on an interesting case of primary cutaneous plasmacytoma with monoclonality of kappa chains. (Korean J Dermatol 2010;48(12):1114∼1117)
정기훈 ( Ki Hun Chung ),고동균 ( Dong Kyun Ko ),원종훈 ( Jong Hoon Won ),박준수 ( Joon Soo Park ),정현 ( Hyun Chung ) 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.8
Myxoid neurofibroma is a histological variant of neurofibroma and represent a conventional neurofibroma with extensive deposition of stromal mucin. Myxoid neurofibroma may present as a sporadic lesion or in the context of neurofibromatosis I. The most common locations of the myxoid neurofibroma are the face, shoulders, arms, periungual area and in the feet. To the best of our knowledge, location in an inguinal area has been rarely reported. We report a case of a 37-year-old man with a solitary myxoid neurofibroma in the right inguinal area. (Korean J Dermatol 2010;48(8):732~734)
이민중 ( Min Jung Lee ),정기훈 ( Ki Hun Chung ),박준수 ( Joon Soo Park ),정현 ( Hyun Chung ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.5
Agminated lentiginosis (AL) is a rare pigmented disorder that is characterized by numerous lentigines in a unilateral distribution or often in a segmental pattern corresponding to one or more dermatomes. AL coexists with other several diseases and some researchers have suggested it is a variant of dermatomal neurofibromatosis if AL is accompanied by cafe-au-lait (CAL) macules or neurofibromas. We report here on a case of a 12-year-old female who presented with multiple lentigines on her right neck and shoulder (the C2 and C3 dermatomes) combined with CAL macule and ipsilateral axillary freckling. On checking the family history, her mother had grouped lentigines on her right chest (the T4, T5 dermatomes). But there were no neurofibromas, Lisch nodules and neurologic or skeletal abnormalities in both of them. (Korean J Dermatol 2010;48(5):416~419)
위선암종에서 Heat Shock Protein 70과 Sulphomucin 발현 양상에 관한 연구
최은아(Eun A Choi),정기훈(Ki-Hun Jung),오민구(Min-Gu Oh),정병욱(Byung-Ook Chung),이준희(Joon-Hee Lee),배성한(Sung-Han Bae),안우섭(Woo-Sub Ahn),서정욱(Joung-Wook Suh),정창영(Chang-Yung Jung),김동훈(Dong-Hoon Kim) 대한외과학회 1999 Annals of Surgical Treatment and Research(ASRT) Vol.57 No.1
반복된 모낭염에 의해 낭성변화를 보인 선천성 멜라닌 세포성 모반
고동균 ( Dong Kyun Ko ),정기훈 ( Ki Hun Chung ),박준수 ( Joon Soo Park ),정현 ( Hyun Chung ),박재복 ( Jae Bok Park ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.12
Nevus with cyst is defined as a single lesion in which there is the coexistence of an epidermoid cyst and a melanocytic nevus. Similar clinical and histopathologic changes can be observed when a hair follicle ruptures and subsequent folliculitis with supprative granulomatous reaction occurs beneath a melanocytic nevus. This cystic change due to inflammation is a different pathologic phenomenon from the formation of an epidermal cyst. Hence, it is necessary to differentiate between these two conditions. We report here on a case of congenital melanocytic nevus combined with cystic change due to inflammation in a 39-year-old man. (Korean J Dermatol 2010;48(12): 1078∼1080)
증숙 오미자의 항산화, 항염증 및 간보호 효과 비교 연구
추병길 ( Byung Kil Choo ),정기훈 ( Ki Hun Chung ),서영배 ( Young Bae Seo ),노성수 ( Seong Soo Roh ) 대한본초학회 2013 大韓本草學會誌 Vol.28 No.2
Objectives: We investigated differances of physiological functionalities in the steamed Schisandrae Fructus. Methods : The samples were extracts of dryed schisandrae fructus without steaming process (S0), extracts of schisandrae fructus with three times steamed (S3), extracts of schisandrae fructus with five times steamed (S5) and extracts of schisandrae fructus with seven times steamed (S7). We analyzed contents of schisandrin, gomisin, total polyphenol and flavonoid and antioxidant activities. We researched antiinflammation effects for Raw264.7 cells. To evaluate liver protective activity, we measured AST, ALT and gamma-GTP in serum of alcoholic mice. Results: As the steaming number of schisandrae fructus increase, the contents of schisandrin and gomisin were more increased. The contents of total polyphenol of S5 and S7 were significantly increased compared to that of S0. DPPH free radical scavenging activities of S5 and S7 were significantly increased compared to that of S0, ABST radical scavenging activities of S3 and S5 were significantly increased compared to that of S0 in vitro. The NO production of all sample was significantly decreased compared to control, PGE2 release of S3, S5 and S7 were significantly decreased compared to control. IL-1β release of S5 and S7 were significantly decreased. AST, ALT and gamma-GTP of S3, S5 and S7 were significantly decreased compared to control. Conclusions: We think that extracts of schisandrae fructus with steaming process may have more potential efficacy than a schisandrae fructus without steaming process.
로터 제자리비행에 적용된 CFD/FreeWake 연계방법의 원거리 경계조건에 대한 연구
위성용(Seong-Yong Wie),이재훈(Jae-Hun Lee),권장혁(Jang-Hyuk Kwon),이덕주(Duck-Joo Lee),정기훈(Ki-Hoon Chung),김승범(Seung-Bum Kim) 한국항공우주학회 2007 韓國航空宇宙學會誌 Vol.35 No.11
본 논문에서는 CFD/FreeWake 연계해석방법을 이용하여 헬리콥터 로터의 공력을 해석하였다. 연계해석방법은 CFD를 이용하여 로터주변의 공력을 얻고, 후류의 거동은 FreeWake를 이용하여 모사한다. FreeWake 모델은 CFD의 경계조건을 제공하고, CFD는 후류형성을 위한 로터블레이드 양력변화율을 제공하는 방법으로 연계된다. CFD/FreeWake 연계해석방법은 다른 로터공력해석 방법에 비하여 높은 정확도와 계산 시간 절감으로 효율적인 계산을 가능하도록 한다. In this study, helicopter rotor flow is simulated by using a tightly coupled CFD/FreeWake method to describe wake characteristics and to calculate the flow field and rotor aerodynamics. In this tightly coupled CFD/FreeWake method, freewake model provides the boundary condition required in the CFD calculation and CFD provides the pressure distribution on blade surface used in feewake generation. To show the advantage of this method, the pressure distributions on blade surface of a hovering 2-bladed rotor are compared with other numerical methods. This tightly coupled CFD/FreeWake method shows good accuracy in the predicted results and efficient computation time.
일측성 신장 무발생(Unilateral Renal Agenesis)을 동반한 과다유두(Supernumerary Nipple)
박준수 ( Joon Soo Park ),정현 ( Hyun Chung ),장효찬 ( Hyo Chan Jang ),정기훈 ( Ki Hun Chung ),이민중 ( Min Jung Lee ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.11
Supernumerary nipple is a developmental anomaly that occurs along the course of the embryological milk lines. The prevalence appears to be higher in women and a wide range of congenital and hereditary anomalies have been described in association with supernumerary nipple, including cardiovascular, gastrointestinal, skeletal and neurologic anomalies, and especially renal and urinary tract anomalies. However, there has been no report of supernumerary nipple with renal anomalies in the Korean dermatologic literature. Herein, we report on an interesting case of a supernumerary nipple with unilateral renal agenesis in a 15-year old man. (Korean J Dermatol 2010;48(11):1008∼1011)
채인수 ( In Soo Chae ),김인용 ( In Yong Kim ),고동균 ( Dong Kyun Ko ),정기훈 ( Ki Hun Chung ),박준수 ( Joon Soo Park ),정현 ( Hyun Chung ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.10
Bullous systemic lupus erythematosus (bullous SLE) is uncommon; distinctive clinical variant of SLE that is characterized by tense vesicles and bullae filled with fluid that occurs on either erythematous or normal skin. Although bullous SLE can accompany erythematous plaque with annular configuration, urticarial papules, and erythema multiforme (EM)-like lesions initially, there is no report of EM-like lesions as an initial sign of bullous SLE in the Korean literatures. Herein, we describe 31-year-old women with bullous SLE that showed EM-like skin lesions as the initial sign.