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장효찬 ( Hyo Chan Jang ),김희정 ( Hee Jeung Kim ),현동녘 ( Dong Nyeok Hyun ),이성우 ( Sung Woo Lee ),정현 ( Hyun Chung ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.10
Poliosis circumscripta describes a localized patch of white hair due to deficiency of melanin in the hair follicles. It is a feature of various conditions such as piebaldism, Vogt-Koyanagi-Harada syndrome, tuberous sclerosis, vitiligo, recent herpes zoster infection, or overlying a scalp neurofibroma. We report a rare case of poliosis circumscripta associated with halo nevus of the scalp. A 24-year-old woman presented with a 10 year history of an asymptomatic, pinkish nodule on the scalp which had overlying poliosis. On histopathological examination, dermal nevus cells were observed and the hair follicles of the depigmented patch were found to be devoid of pigment. (Korean J Dermatol 2006;44(10):1250~1252)
Cyclosporine 투여로 호전을 보인 Ofuji 구진성 홍피증
장효찬 ( Hyo Chan Jang ),김희정 ( Hee Jeung Kim ),현동녘 ( Dong Nyeok Hyun ),이성우 ( Sung Woo Lee ),정현 ( Hyun Chung ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.1
Papuloerythroderma of Ofuji is an uncommon dermatological disorder of unknown etiology and is characterized by a pruritic eruption of widespread confluent papules in vast sheets over the skin, but spares the skin folds (the so-called `deck-chair` effect). We present a case of a patient with papuloerythroderma of Ofuji of unknown cause. Treatment with oral and topical corticosteroids, antihistamines, and narrow-band UVB phototherapy proved to be ineffective in helping the condition but considerable clinical improvement was obtained with cyclosporine. (Korean J Dermatol 2007;45(1):37~39)
장효찬 ( Hyo Chan Jang ),박근 ( Gun Park ),김희정 ( Hee Jeung Kim ),이성우 ( Sung Woo Lee ),정현 ( Hyun Chung ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.1
Pyoderma gangrenosum has been described in association with a wide variety of disorders, inclusding Crohn`s disease, ulcerative colitis, myeloproliferative disease, monoclonal gammopathy, and Behcet`s disease. Herein, we report two cases of pyoderma gangrenosum associated with Crohn`s disease. The first case was a 24-year-old female who presented with multiple, necrotizing ulcers on the scalp, which is a rarely affected site. The other case was a 30-year-old female who presented with erythema nodosum on the lower leg initially, and subsequent rapidly-progressive ulceration lesions then developed at the previous biopsy and intravenous injection sites. In both cases, the colonoscopic findings were consistent with Crohn`s the lesions improved with a combined therapy of systemic steroids, sulfa drugs and topical 0.03% tacrolimus ointment. (Korean J Dermatol 2007;45(1):63~68)
안 침범이 동반된 전신성 일광 육아종 환자에서 발생한 측두 동맥염
장효찬 ( Hyo Chan Jang ),김희정 ( Hee Jeung Kim ),박근 ( Gun Park ),정현 ( Hyun Chung ),도진국 ( Jin Kuk Do ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.8
A 63-year-old Korean man presented with generalized, asymptomatic, discrete papules and coalescent annular plaques for one year. Interestingly, the patient complained of conjunctival congestion, concurrently with aggravation of the skin lesion. Histopathologic findings of the skin lesion and conjunctiva revealed giant cells engulfing fragmented elastic fibers, and a diagnosis of actinic granuloma with ocular involvement was made. Ten months later, the patient revisited with a two-week history of bilateral temporal headache, neck pain, intermittent jaw claudication, and blurred vision. Biopsy of the temporal artery confirmed the clinical diagnosis of temporal arteritis. Both actinic granuloma and temporal arteritis show similar pathologic process, and this case supports the hypothesis that actinically degenerated elastic tissue is likely to be the antigenic basis of actinic granuloma of the skin and temporal arteritis. (Korean J Dermatol 2007;45(8):814∼817)