http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이용춘,강익중 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.3
A drug delivery system was designed to maximize the treatment effect for effective drug targeting to specific regions. Drug delivery carriers should safely transport drugs to a specific region in the body. As a nontoxic biocompatible polymer obtained by deacetylation of chitin, chitosan is suitable for use as an anticancer agent delivery carrier. Using gold as an additional nanoparticles is useful as it forms a nano-complex comparatively quickly when linked with chitosan because the nanoparticle has a negative charge. Additionally, when external energy is applied, gold-coated nano-complexes generate heat to emit the absorbed drugs because of their unique metallic properties. Fe3O4 is an oxidized nano size metal with excellent magnetic properties; unlike other metals, it is nontoxic. In this study, the quantities of the reductant, catalyst, and solvent inside the chitosan–Fe3O4–gold nanoshell generated by ionic interactions between the amine, an end group of chitosan, and the metalic nanoparticles were altered and changes to the system evaluated to identify optimal reaction conditions for the drug delivery carrier, which were as follows: 30 μL of 16.5 wt % ascorbic acid, 1.5 mL of 1 wt % gold solution, and 30 μL of 28 wt % ammonium hydroxide.
이용춘,Sheng Zheng,Huang Yao 한국천문학회 2019 Journal of The Korean Astronomical Society Vol.52 No.2
The New Vacuum Solar Telescope (NVST) is the largest solar telescope in China. When using CCDs for imaging, equal-thickness fringes caused by thin-film interference can occur. Such fringes reduce the quality of NVST data but cannot be removed using standard flat fielding. In this paper, a correction method based on multi-scale decomposition and adaptive partitioning is proposed. The original image is decomposed into several sub-scales by multi-scale decomposition. The region containing fringes is found and divided by an adaptive partitioning method. The interference fringes are then filtered by a frequency-domain Gaussian filter on every partitioned image. Our analysis shows that this method can effectively remove the interference fringes from a solar image while preserving useful information.
QDs를 이용한 키토산-골드와 키토산-실버 나노약물전달체 제조
이용춘 ( Yong-choon Lee ),강익중 ( Ik-joong Kang ) 한국화학공학회 2016 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.54 No.2
본 연구에서는 최근 많은 분야에서 응용되고 있는 형광물질인 양자점을 생명고분자인 키토산과 반응시켜 얻은 나노입자와 금속성 골드 나노입자, 그리고 실버 나노입자로 외부를 코팅하여 나노약물 전달체를 얻을 수 있었다. 키토산은 생체고분자로써 무독성이며 인체적합성 고분자이다. 양자점은 2~10 nm의 크기를 가지는 반도체성 나노입자이다. 양자점은 생명분자나 생명단백질의 비슷한 크기를 갖으며, 그 크기에 따라 알맞은 가시광선 영역의 빛을 발산할 수 있도록 조절 가능하므로, 세포 바이오 마킹, 약물전달체 등에 효과적으로 쓰일 수 있다. 따라서 키토산 나노입자 말단의 아민기와 양자점의 카르복실기가 아미드결합을 형성하여 반응하게 조절하였다. 양자점의 독성을 완화시키기 위해 코팅재료로 사용된 금속성 나노입자 중 골드나노입자는 약 5~10 nm의 크기를 가지고 있고, 인체에 무해하고 음전하를 띄어서 양전하를 띈 고분자와 쉽게 복합체를 형성할 수 있는 장점이 있다. 향균성으로 잘 알려진 실버나노입자는 약 5 nm의 크기를 가지고 있고, 은 나노입자로 코팅을 하면 미생물 감염을 미리 방지 할 수 있는 장점을 가지고 있다. 본 연구에서 만들어진 QDs-키토산-골드 & QDs-키토산-실버 나노쉘의 입자크기는 약 100 nm의 크기를 갖었으며, 목적하는 바 형광특성을 잘 보여주고 있었다. 이러한 입자들은 정전기적 상호작용에 의하여 각각 골드나노입자와 실버나노입자로 코팅되어 나노 약물전달체로 완성할 수 있었다. A drug transport carrier could be used for safe send of drugs to the affected region in a human body. The chitosan is adequate for the drug delivery carrier because of adaptable to living body. The gold, a metallic nanoparticles, tends to form a nano complex at rapidly when it combined with chitosan because of its negative charge. having energy from the other, outer gold nano-complex make heat due to its property to release the contained drugs to the target area. Silver could be also formed an useful biocompatible nano-composites with chitosan which should be used as an useful drug transfer carrier because its special ability to protect microbial contamination. Being one of the oxidized nano metals, Fe3O4 is nontoxic and has been used for its magnetic characteristics. In this study, the control of catalyst, reducing agent, and solvent amount. The chitosan-Fe3O4-gold & silver nanoshell have been changed to form about 100 nm size by ionic bond between the amine group, an end group of chitosan, and the metal. It was observed the change in order to seek for its optimum reaction condition as a drug transfer carrier.
정효중,정수성,양윤석,이용춘,한정수 한국광학회 2020 한국광학회지 Vol.31 No.6
The optics used in an infrared imaging system have a strong refractive-index change according to temperature, so an autofocus control function is essential for a military infrared imaging system with a wide operating-temperature range. In this study, we design a triple-magnification infrared imaging system, and to compensate for the change in refractive index according to temperature we measure the change in the focus lens according to temperature. The autofocus control function was implemented by using the measured movement amount, and we could obtain an image with satisfactory resolution performance over a wide range of operating temperatures.
Gender Differences in Sleep Disturbance among Elderly Koreans: Hallym Aging Study
Shan-Ai Quan,이용춘,Wen-Jie Li,정진영,김동현 대한의학회 2016 Journal of Korean medical science Vol.31 No.11
Sleep is an important component in our lives as it is necessary throughout one’s entire life span. This study was conducted to elucidate whether there are gender differences in sleep quality and what factors can affect sleep quality in community-dwelling elderly Koreans. A total of 382 subjects (175 males and 207 females) were recruited among elderly aged 45 or over who participated in the 2010 Hallym Aging Study (HAS). They were invited to a general hospital and were evaluated for socioeconomic status, smoking history, and various clinical measures. Sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI). A higher score indicates poorer subjective sleep quality, (PSQI global score > 5 suggests sleep disturbance). After adjusting for potential covariates, our results show that alcohol increases the odds for poor sleep (odds ratio [OR] = 3.35, 95% confidence interval [CI] = 1.11–10.10) in males. In females, lack of exercise was the major risk factor of poor sleep as they are 4.46 times more likely to suffer from low sleep quality than those who exercise regularly (95% CI=1.56–13.75). Stress was also a risk factor for poor sleep. It was 5.60 times higher in the “always have stress” group than the “do not have stress” group (95% CI = 1.54–20.34). Thus, alcohol consumption is associated with men’s sleep quality, while exercise and stress level affect women’s.
확산 스펙트럼 생성기를 이용한 적외선 카메라의 방사노이즈 저감에 관한 연구
최봉준(Bongjun Choi),이용춘(Yongchun Lee),윤주현(Juhyun Yoon),김은준(Eunjun Kim) 한국전자파학회 2016 한국전자파학회논문지 Vol.27 No.12
적외선 카메라는 Mil-Std-461 항목 중 복사성 방사 잡음 시험, RE-102의 규격 만족에 어려움을 겪는다. 특히 무인항공기용 전자장비의 경우 차폐 케이블을 사용하지 않아 전자기적합성 규격 만족이 어려워 적절한 대응 설계가 필요하다. 무인정찰기용 적외선 카메라의 RE-102 시험 중 50~200 MHz 대역에서 30 dBuV/m 이상 규격을 초과하는 방사 잡음을 확인하였다. Pcb em scan 결과, 디지털 제어 신호 클록의 체배 주파수에 의한 첨두 잡음 발생을 확인하였고, 카메라의 제어 클록에 3 % 다운 스프레딩 방식의 확산 스펙트럼 클록 생성기를 적용하여 방사 잡음이 최대 22.9 dBuV/m 감소함을 확인하였다. The infrared camera is difficult to satisfy the RE-102 specification of Mil-Std-461. Especially, in the case of UAV electronics, shielded cable is not used, so it is difficult to meet the electromagnetic compatibility standard. In the RE-102 test of the IR camera for UAV, radiated noise exceeding 30 dBuV/m was observed in the range of 50 MHz to 200 MHz. As a result of pcb em scan, peak noise which caused by the harmonic frequency of the digital control signal clock was observed. Radiated noise was reduced by up to 22.9 dBuV/m by applying the spread spectrum clock generator(SSCG) with 3 % down spreading method to the camera control clock.