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- 저자 : 이상억(Sang Eog Lee) (검색결과 4 건)
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한국인에서 경동맥 경화와 관상 동맥 질환의 연관 관계에 관한 연구
이상억(Sang Eog Lee),김권삼(Kwon Sam Kim),김병준(Byoung Joon Kim),이효정(Hyo Jung Lee),안우석(U Seouk Ahn),강흥선(Heung Sun Kang),조정휘(Chung Whee Choue),김명식(Myung Shick Kim),송정상(Jung Sang Song),배종화(Jong Hwa Bae) 대한내과학회 1996 대한내과학회지 Vol.51 No.6
N/A Objectives: Along with the recent change in lifestyle in Korea, the incidence of coronary artery disease(CAD) and cerebrovascular disease due to atherosclerosis has increased. B-mode ultrasound of the extracranial carotid arteries offers a valid and repeatable noninvasive method for quantifying the extent of atherosclerosis. The extent of carotid artery atherosclerosis as measured by B-mode ultrasound has been shown to be strongly and independently correlated with the presence or absence of CAD. We investigated the relation between carotid atherosclerosis and the status of CAD in Korean population with a carotid B-mode ultrasound. Methods: One hundred twenty eight patients underwent. B-mode ultrasound of the carotid arteries with 10 MHZ linear array probe. The intima-media thickness(IMT) at two sites in far(posterior) wall of the both common carotid artery and bifurcation were quantified and evaluated for the incidence of softand hard plaques. Coronary angiography was performed by the percutaneous technique using Judkins catheter. The extent of CAD was counted as 0,1,2,3-vessel disease according to the number of major coronary vessels with an obstruction of 50% or greater. Results: The number of coronary artery involved was single-vessel disease in 41, two-vessel disease in 19, three-vessel disease in 25 and no corona atherosclerotic disease in 43. The incidence of plaques was no CAD group in 10(23%) at the bifurcation, whearas CAD group in 18(23%) at the common carotid artery and 68(80%) at the bifurcation. The incidence of plaques at the bifurcation increased progressively in each of 2- and 3-vessel disease group compare with the 1-vessel disease group(89%, 100% vs 64%). The sum of IMT at both common carotid artery and bifurcation was significantly different between no CAD and CAD group(3.17±0.08mm vs 4.26±1.37mm, p<0,05), and increased progressively in each of the groups with increasing numbers of stenosed vessels(2-vessel clisease:4.98±1.28mm, 3-vessel disease: 5.29±1.20mm Conclusion: The results suggest that increased IMT of carotid arteries is closely related to status and extent of CAD Also measurement of IMT may be useful screening method for assessment of CAD and systemic atherosclerosis.
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김재필(Jae Pill Kim),최남수(Nam Su Choi),임성식(Sung Shick Lim),이상억(Sang Eog Lee),홍화정(Hwa Jung Hong),홍성표(Seong Pyo Hong),이태원(Tae Won Lee),임천규(Chun Gyoo Ihm),김명재(Myung Jae Kim),박원도(Won Do Park),김영훈(Yeong Hoon K 대한내과학회 1997 대한내과학회지 Vol.52 No.5
N/A Objective: Acute Renal Failure is a clinical syndrome characterized by a sudden decrease in renal function which was previously normal. Despite advances in medical care, prognosis in ARF is variable according to the influence of demographic factors, severity of ARF, nature of disease causing ARF, coexisting disease, treatments applied, and complications. We studied the recent changes of clinical feature of ARF. Mcthods: We studied retrospectively 245 patients with ARF who had been hospitalized at Kyung Hee University Hospital between February 1988 and March 1993. Results: 1) Male to female sex ratio was 1.8:1, and the incidence was high in above fifth decade (67.8%). 2) Acute renal failure was classified, according to clinical background, into medical group 79.6% (195 cases) and surgical group 20.4% (50 cases), and oliguric group 40.8% (100 cases) and non-oliguric group 59.2% (145 cases). 3) Acute renal failure due to medical causes included ARF by hemorrhagic fever with renal syndrome (25.6%), drugs and chemicals (17.9%), sepsis (17.4%) and systemic infection (7.7%) etc. ARF due to surgical causes included ARF by multiple trauma (34%), various surgical procedures (30%), surgical sepsis (14%), burn (12%) etc. 4) During admission, the expired patients had more severe biochemical and clinical characteristics including high BUN and serum potassium (p<0.01), lower serum albumin (p<0,01) than those of survivor. 5) Infections as the cause of ARF were 107 cases (43.7%), which included hemorrhagic fever with renal syndrome 50 cases, sepsis 31 cases, urinary tract infection 7 cases and respiratory tract infection 6 cases etc. The most common infecting organism was Hantavizus (50.5%). There was a greater number of gram-negative organisms than gram-positive organisms (34.1% vs 9.9%). 6) The overall mortality rate in patients with ARF was 31.4Fo. The presumptive causes of death were underlying disease (59.7%) such as sepsis, acute poisoning, cardiogenic and hypovolemic shock, and respiratory failure (14.3%), hyperkalemia (9.1%), pulmonary edeme (6.5%), and metabolic aidosis (2.6%) in order of frequency. 7) The highest mortality rate was 42.6% in patients above 50 years old. Mortality rate in patients with ARF due to surgical causes (52.0%) was significantly high than that of medical causes (26.2%) (p<0.05). Among the expired patients, oliguric group was 72.7%. In conclusion, there have been major trends in the clinical features of acute renal failure in this study. Especially, significant increase in the number of elderly patients, non-oliguric patients, and medical causes such as hemarrhagic fever with renal syndrome or sepsis were observed. Survival rate significantly decreased with increasing age, in acute renal failure by surgical causes, in oligurie patients, and in the presence of complicating factors such as sepsis or shock.
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요관결석환자에서 발생된 Salmonella typhi 에 의한 Acute Focal Bacterial Nephritis
홍성표,김명재,이태원,김병준,김기중,안우석,이상억,원현상,현용준,성낙천,임천규 대한내과학회 1996 대한내과학회지 Vol.51 No.6
Acute focal bacterial nephritis(AFBN; Acute lobar nephronia) represents a acute, localized, non necrotizing suppurative inflammation of an entire lobule of kidney analogue to segmental involvement of the lung in lobar pneumonia. Renal Abscess, renalcyst and renal cell cancer, which also may appear as a mass, is distinguished radiologically from AFBN by abdominal ultrasonogram, abdominal CT scan, kidney MRI and renal scan. We have experienced a case of a 50-years-old male with acute focal bacterial nephritis by Salmonella typhi with ureteral stone. The patient was treated with chloramphenicol for 3 weeks and discharged, After 5 weeks later, the sonographic examination revealed reduced size of mass at affected kidney. We report this case with review of literatures.
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