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가미통규탕(加味通竅湯)이 호흡기 뮤신 분비 및 기관 평활근 긴장도에 미치는 영향
이남열,한재경,김윤희,Lee, Nam-Yeol,Han, Jae-Kyung,Kim, Yun-Hee 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.3
Objectives In the present study, the author intended to investigate whether Gamitonggyu-tang (GTT) significantly affects (since the subject is GTT, you need an 's') in vivo and in vitro mucin secretion from airway epithelial cells. Methods In vivo experiment, mice's mucin which is on a hypersecretion of an airway, mice's tracheal goblet cells in hyperplasia and mice's intraepithelial mucosubstances were exposed with SO2 for 3 weeks. Effects of orally-administered GTT for 1 week on in vivo mucin secretion and hyperplasia of tracheal goblet cells were assessed by using enzyme-linked immunosorbent assay (ELISA) and staining goblet cells with alcian blue. In vitro experiment, confluent hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with 3H-glucosamine for 24 hrs and chased for 30 min in the presence of GTT to figure out the effectiveness of 3H-mucin secretion. Total elution profiles of control spent media and treatment sample through Sepharose CL-4B column were analyzed.Possible cytotoxicities of each agent were assessed by measuring lactate dehydrogenase (LDH) release. Also, the effect of GTT on contractility of isolated tracheal smooth muscle was investigated. Results (1) GTT inhibited hypersecretion of in vivo mucin. However, it did not affect the increase the number of goblet cells (2) GTT significantly increased mucin release from cultured HTSE cells, without significant cytotoxicity (3) GTT chiefly affected the 'mucin' secretion and did not affect the secretion of the other releasable glycoproteins with less molecular weight than mucin (4) GTT did not affect Ach-induced contraction of isolated tracheal smooth muscle.Conclusions This result suggests that GTT can increase mucin secretion during short-term treatment (in vitro) whereas it can inihibit hypersecretion of mucin during long-term treatment (in vivo). The author suggests that the effect GTT with their components should be further investigated and it is valuable to find from oriental medical prescriptions, novel agents which might regulate mucin secretion from airway epithelial cells.
이남열,한재경,김윤희,Lee, Nam-Yeol,Han, Jae-Kyung,Kim, Yun-Hee 대한한방소아과학회 2008 대한한방소아과학회지 Vol.22 No.1
Objectives This study is to investigate the effects of oriental medical treatment for traumatic cerebral infarction. Methods We treated the patients with herbal medicine, acupuncture, aroma therapy, rehabilitation, and we evaluated these cases with Activity Index. Results There are some improvements in each patients, such as manual muscle power, finger apraxia after oriental medical treatments. Conclusions We report a change for the better effect of oriental medical treatment on this case. The more clinical studies of oriental medical treatment for traumatic cerebral infarction are needed.
뇌파측정을 이용한 비염 환아와 정상아의 주의집중력에 관한 연구
이남열,김윤희,한재경,Lee, Nam-Yeol,Kim, Yun-Hee,Han, Jae-Kyung 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.2
Objectives : Allergic children have known to have multiple behavior problems. Among them, attentional ability disorder is one of the most common problems. This study is to examine relationship between learning ability and allergic rhinitis by analyzing EEG status of children. Methods : We analyzed cognitive functions of two different children groups; 21 children with allergic rhinitis and 19 normal children with CANS 3000(Central & Autonomic Nervous System, LAXTHA Inc., Korea), cognitive functions assessment program by EEG. Results : 1. According to mean active EEG rhythm of Theta, Alpha, SMR, M-beta, there were no significant difference between allergic rhinitis and the normal group. 2. According to mean active EEG rhythm of right H-beta, Gamma wave allergic rhinitis group's value was significantly higher than that of the normal group. 3. According to mean cognitive strength, response, concentration, left / right brain activity and learning ability score, there were no significant difference between allergic rhinitis and the normal group. 4. According to mean workload score, allergic rhinitis group's value was significantly higher than that of the normal group. Conclusions : It is likely that allergic rhinitis group, which showed relatively high frequency EEG rhythm, is more fragile to stress and less active on mental processing. Along side with physical examination, psychological assessment should also be conjugated on treating children with allergic rhinitis.
한재경,김윤희,이남열,Han, Jae-Kyung,Kim, Yun-Hee,Lee, Nam-Yeol 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.2
Objective : In order to educate juveniles with proper sex education and to present advisable sexual culture among them, we researched the revelation age and duration period of secondary sex characteristics of 5th and 6th elementary student in Cheon-an, and compared them with their mother's case. Method : We did a survey among 5th and 6th grade elementary student in Cheon-an, which includes pictures presenting, different stages of breasts and pubic hair development. Results : Results show that in girls, average menarche age was 11.47 while the average of their mother's was 14.25. 3 years of decline was observed. On boys, average pubic hair development age was 11.42, similar to the average age of voice change, 11.43. Girls showed relatively earlier distribution of pubic hair manifestation age of 11.39, than in boys, which was 11.42. Concerning the sexual maturity, 99% of girls were over B2, while 43% of boys were over PH2. Almost all of the female participants manifested secondary sex characteristics, and half of them were in the stage of pubic hair development. Conclusion : We observed that the average age of manifesting secondary sex characteristic among elementary students is getting younger and especially, menarche age of young girls is significantly showing downward tendency compared to their mothers'. Sex education in elementary schools should be carried out considering the development stage of secondary sex characteristics among students.
조상범(Sang-Bum Cho),이남열(Nam-Yeol Lee),전영승(Young-Seung Jun),진광범(Kwang-Bum Jin),최민서(Min-Seo Choi) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1B
MPEG그룹은 미디어 객체를 시간과 3차원 공간상에 배치하여, 멀티미디어 컨텐츠를 표현하고, 사용자의 상호작용을 가능하게 하는 MPEG-4 System을 표준화하였으며, 다양한 전송계층 (File, TCP/IP, Broadcasting등)을 통합하여 처리할 수 있는 DMIF (Delivery Multimedia Interface Framework)[3] 전송규약을 표준화하였다. 이 논문에서는 MPEG-4 System의 BIFS와 SCENE을 제작할 수 있는 저작툴의 설계와 구현을 함으로써 MPEG-4 System을 이용하여 비디오, 오디오, 그래픽과 같은 다양한 미디어들을 결합해주고 사용자와의 상호작용에 의한 실시간 표현을 가능하게 해주며 사용자가 MPEG-4 System에 대해서 잘 알고 있지 않더라도 손쉽게 MPEG-4 미디어 파일을 만들 수 있도록 해주는 저작툴을 제안한다[1,3,5].