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윤영순 ( Young Soon Yoon ),김경선 ( Kyung Sun Kim ),정선영 ( Sun Young Jeong ),박근민 ( Gun Min Park ),손성욱 ( Seong Wook Sohn ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.1
Background: Antibiotics skin test (AST) is routinely performed to examine hypersensitivity in clinical practice. However, it is difficult to select antibiotics in case of positive AST because of poor validation of AST, crossreactions among β-lactams, etc. Objective: To evaluate the change of antibiotics and following results in case of positive AST. Method: Eighty-six hospitalized patients with positive AST between June 2008 and May 2009 were enrolled. The changing patterns of antibiotics, skin test-reactivity of changed antibiotics, history of antibiotics allergy and adverse events after administration of antibiotics were examined in review of medical records. Result: The patients with positive AST were 95 cases. The skin test positive-antibiotics were 11 penicillins and 84 cephalosporins, respectively. The finally administered antibiotics were changed in 84 patients except 2 patients, which were non β-lactams in 13 patients, cephalosporins in 59 patients, and penicillins in 14 patients. Total 3 (3.5%) adverse reactions (ADRs) were reported. Among them, one was reported in 2 patients whose antibiotics were not changed and 2 (2.4%) in remaining 84 patients. Conclusion: Most antibiotics were changed and the changing patterns of antibiotics were varied in case of positive AST. The guidelines for changing antibiotics are needed. (Korean J Asthma Allergy Clin Immunol 2011;31:48-54)
항산균 도말 검사, 세포진 검사가 음성이고, ADA와 CEA가 낮은 림프구성 흉막 삼출증의 임상 양상과 예후
강영애 ( Young Ae Kang ),윤영순 ( Young Soon Yoon ),이세원 ( Sei Won Lee ),최창민 ( Chang Min Choi ),김덕겸 ( Deog Kyeom Kim ),이희석 ( Hee Seok Lee ),고동석 ( Dong Seok Ko ),유철규 ( Chul Gyu Yoo ),김영환 ( Young Whan Kim ),한성 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.58 No.1
연구 배경 : 흉수의 항산균 도말과 세포진 검사가 음성이며, 흉수의 ADA 가 40 IU/L 이하, CEA가 10ng/ml 이하인 림프구성 흉막 삼출증의 임상적 특징과 예후를 살펴보고자 한다. 연구 방법 : 2000년 1월 1일부터 2001년 8월 31일 사이에 서울대학교 병원을 방문한 림프구성 흉막 삼출증 환자들 중 흉수의 항산균 도말과 세포진 검사가 음성이며, 흉수의 ADA가 40 IU/L 이하, CEA가 10ng/ml 이하인 환자들의 의무 기록을 Background : A pleural effusion is a common medical problem. Despite several diagnostic tests, 15-20% of pleural effusions go undiagnosed. The aim of this study was to evaluate the clinical characteristics and prognosis of a lymphocyte dominant exudative
공동성 폐결핵으로 오인된 만성 괴사성 폐 아스페르길루스증
민주원 ( Joo Won Min ),윤영순 ( Young Soon Yoon ),박종선 ( Jong Sun Park ),김혜련 ( Hye Ryoun Kim ),이지영 ( Ji Young Rhee ),유철규 ( Chul Gyu Yoo ),김영환 ( Young Whan Kim ),한성구 ( Sung Koo Han ),심영수 ( Young Soo Shim ),임재 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.4
Pulmonary cavities are caused by bacterial pneumonia, fungal diseases, lung cancer, and tuberculosis (TB). However, in Korea, patients with cavitary lung lesions are generally considered to have pulmonary TB, where the incidence of TB is approximately 70/100,000 per year. We report a case of chronic necrotizing pulmonary aspergillosis that was obscured by multidrug-resistant pulmonary TB. (Tuberc Respir Dis 2007; 63: 368-371)
고형암에 대한 항암화학요법 치료 중 병발한 결핵의 특성
김덕겸 ( Deog Kyeom Kim ),이세원 ( Sei Won Lee ),강영애 ( Young Ae Kang ),윤영순 ( Young Soon Yoon ),유철규 ( Chul Gyoo Yoo ),김영환 ( Young Whan Kim ),한성구 ( Sung Koo Han ),심영수 ( Young Soo Shim ),임재준 ( Jae Joon Yim ) 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.58 No.3
연구 배경 : 면역 기능 저하를 초래하여 결핵의 재활성화에 관여할 것으로 생각되는 주기적인 항암화학요법치료 중인 고형암 환자에서 발생한 결핵의 임상적 특징과 치료 반응을 파악하고자 하였다. 대상 및 방법 : 2000년 1월부터 2004년 7월까지 국내 일개 3차 병원에서 항암화학요법 치료 중에 세균학적으로, 병리학적으로 또는 임상적으로 진단된 결핵 환자 중 기존에 알려진 결핵 재활성화의 위험 요인이 없는 22명을 대상으로 후향적 연구를 시행하였다. 결과 Background : Some malignancies including lymphoma, head and neck cancer, and lung cancer are believed to be associated with the reactivation of tuberculosis (TB) because cyclic anti-cancer chemotherapy can induce the leukopenia or immunological deteriorat