http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
원저(原著) : 수혈에 의한 이식편대숙주병 예방을 위한 혈액제제의 방사선조사
유승국 ( Seung Gug Yoo(m. T. ) ),류광현 ( Kwang Hyun Ryu(m. T. ) ),송운흥 ( Woon Heung Song(m. T. ) ) 대한임상병리사협회 1995 임상수혈검사학회 발표자료집 Vol.2 No.1
The aim of irradiating blood components is to inactivate T lymphocytes which Transfusion-associated Graft-versus-host-disease(TA-GVHD). TA-GVHD usually occurs in the immunosupressed recipient(eg, infants with congenital immunodeficiency syndromes and bone marrow transplant recipients), and in an immunocompetent patient who receive HLA-homozygous blood for the recipient`s haplotypes. Most blood component that contains viable T lymphocytes must be irradiated according to the indication transfusion to prevent TA-GVHD. All the red cell concentrates, whole blood, platelet concentrates, granulocyte concentrates contain many lymphocytes but fresh frozen plasma and cryoprecipitate show no viable cells. The minimal recomended dose for gamma radiation is 25 GY(2500 rads). however currently, different dose are used according to the institution.
원저(原著) : ABO 부적합 조혈모세포 이식에서의 혈액지원 경험
유승국 ( Seung Gug Yoo ),남정현 ( Chung Hyun Nahm ),배수환 ( Soo Hwan Pai ) 대한임상병리사협회 1999 임상수혈검사학회 발표자료집 Vol.5 No.1
From January 1997 to February 1999. 3 major ABO-incompalible PBSCT. 2 mlnor ABO-incompatible PBSCT. 2 allogenic BMT, 11 autologous PBSCT were performed in Inha University Hospital. Among 18 cases. We report 2 cases of ABO incompatible Peripheral Blood Stem Cell Transplantation and also recommended ABO group of blood components for use in patients receiving ABO incompatible marrow. Additionally We emphasized the blood components usage according to the type of ABO incompatible PBSCT and suggest a guidline for its optimal blood components. After Bone Marrow Transplantation(BMT).the recipient must receive transfusion support until engraftment occus and blood cell production is adequate. Especially Bone Marrow tranaplantation requires.such as filtered and irradiated blood cellular components. All cellular blood components must be irradiated to prevent multiplication of viable donor lymphocytes and consequent Graft Versus Host Disease(GVHD).Removed leukocytes from red blood cells or platelet concentrates is recogniged to be the most effective way of preventing such posttransfusion complications as Non-Hemolytic Febrile Transfusion Reaction. platelet refractoriness, CMV Infections,and Immunosupression.
원저(原著) : 자가면역용혈성빈혈에 의한 ABO불일치 결과의 해석 (한냉응집증후군의 예)
유승국 ( Seung Gug Yoo ),김미정 ( Mi Jung Kim ),김운영 ( Woon Young Kim ),이명권 ( Myoung Kwon Lee ),남정현 ( Jeong Hyun Nam ) 대한임상병리사협회 1997 임상수혈검사학회 발표자료집 Vol.4 No.1
54세의 자가면역용혈성빈혈 환자에서 발생한 ABO 불일치를 한냉자가항체에 의한 원인으로의심하였고 DAT, IAT 검사, 자가항체검사, 한냉응집소역가검사, 특이항체검사 등을 실시하여 ABO 불일치현상을 해결하였기에 보고하는 바이다. An ABO discrepancy was observed in a 54-year-old patient with cold agglutinin syndrome, classification of autoimmune hemolytic anemia(AIHA) and with liver disease, renal disease. The patient`s red cells was typed AB and his serum had both anti-A and anti-B. An autocontrol positive and the DAT(direct antiglobulin test) is strongly positive. The patient`s we obtained the following results : 1. DAT is strongly positive(complement is the only protein detected on RECs) 2. Type of hemolytic anemia associated with cold-reactive autoantibodies. 3. Cold-reactive autoagglutinin titer is above 1,000. 4. Anti-I is seen. 5. Spherocytes, target cells and anisocytosis are seen on the red blood cell morphology. 6. Mycoplasma Ab is positive(1 : 80) 7. Additional test : each laboratory test. 8. Cell typed was "AB" and serum typed "O" but the result proved to group "A" In pretransfusion tests on patients with autoantibodies, cold-reactive autoantibodies, resulting in erroneous determinations of ABO and Rh type. CAS(cold agglutinin syndrome) is the most common type hemolytic anemia associated with cold-reactive autoantibodies, and accounts for approximately 16~32% of all cases of immune hemolysis. It is only necessary to maintain the blood sample at 37℃ immediately after collection and to wash the red blood cells with warm saline before testing.