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UAV 공중 통신을 위한 Air-to-Air 채널 모델링 및 OFDM 시스템 성능 평가
엄준수(Joon-Soo Eom),강길모(Gil-Mo Kang),신요안(Yoan Shin),신오순(Oh-Soon Shin),박재수(Jaesoo Park),최효기(Hyogi Choi),황찬호(Chanho Hwang) 대한전자공학회 2020 전자공학회논문지 Vol.57 No.3
UAV가 대중화되고 통신 기능을 탑재하면서 UAV의 응용 분야는 기상 관측, 자연재해 감지, 교통 통제, 화물 운반, 네트워크 커버리지 확장 등 다양한 영역으로 확대되고 있다. 특히, 네트워크 커버리지 확장을 위해 기존의 지상망에 릴레이 기능을 하는 UAV를 도입하여 지상 기지국에서 멀리 떨어진 UAV의 통신을 지원할 수 있다. 이 경우 지상 기지국과 릴레이 UAV 간의 통신뿐만 아니라 릴레이 UAV와 다른 UAV 간의 공중통신이 필요하다. 본 논문에서는 UAV 간의 공중 통신 환경에서 거리, 상대 속도, 고도에 따른 채널 특성의 변화를 반영하는 경로손실 모델, 시간 지연 모델, Doppler 확산 모델을 제시하고 이를 통합한 공중 통신채널 모델을 제안한다. 또한, 공중 통신용 다중 Numerology OFDM 시스템을 설계하고 제안한 채널 모델을 이용하여 다양한 환경에서 성능을 평가한다. Applications of unmanned aerial vehicles (UAVs) are expanding to various areas, such as weather monitoring, sensing of natural disasters, traffic control, transportation of commodities, and network coverage extension, as UAVs are popularized and equipped with communication functionality. In order to extend the network coverage, in particular, UAVs can be used as relays between a ground base station and other UAVs far from the ground base station. In this scenario, we need air-to-air (A2A) communications between the relay UAV and other UAVs as well as air-to-ground (A2G) communications between the ground base station and the relay UAV. In this paper, we focus on A2A communications. We first develop an A2A channel model that incorporates the path loss, delay spread, and Doppler spread models, which are functions of the distance, relative velocity, and altitudes of UAVs. Then, we design an A2A communication system based on orthogonal frequency division multiplexing (OFDM) and access its performance under various A2A channels.
국내 허가된 유전자재조합의약품 품질시험에 사용되는 전하변이체 분석법 조사연구
엄준호(Joon Ho Eom),백정희(Jounghee Baek),홍영기(Young Ki Hong),손애라(Aera Son),강소영(Soyeong Kang),오호경(Hokyung Oh),김민정(Min-Jung Kim),우정남(Jeong-Nam Woo),안치영(Chiyoung Ahn) 대한약학회 2020 약학회지 Vol.64 No.1
Analysis on approval documents of recombinant DNA-derived biopharmaceuticals (172 items) marketed in Korea showed as followed. First of all, antibody drugs are about 37% among the biopharmaceuticals and most of antibodies as a major ingredient (about 92%) are humanized or human type. Second, charge variant assays using in quality (purity) test are distinctly different between antibody drugs and non-antibody drugs. The former prefer CEX and cIEF, the latter IEF and CZE. The preference difference may be related to size and complexity of target molecules. Third, the result of analysis on usage of 4 assays (CEX, CZE, IEF, and cIEF) in accordance with approval period indicated that cIEF usage got increased since 2010 and was about 50% after 2015. And finally, acceptance criteria of charge variant assays showed a few distinguished patterns independent of drug products. In the light of these facts, whether or not to establish a charge variant method and acceptance criteria as a quality test, and which method to use may depend on the characteristics of the product and analysis conditions of other manufacturers. In particular, in biopharmaceuticals that contain polymer proteins as the main component, such as antibodies, charge variant analysis is important, and the use of modern analytical methods such as the icIEF method is expected to increase.