체중조절 기전과 항비만 기능성물질

안인숙,박건영,도명술,Ahn, In-Sook,Park, Kun-Young,Do, Myoung-Sool 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.4

The obese population has been increasing worldwide and obesity has become one of the socioeconomic problems. Obesity raises more concerns as more studies regarding its direct and indirect relativity to several diseases such as type II diabetes, hypertension, etc. are published. Since leptin, an important signal in the chronic control of food intake and energy expenditure, was discovered in 1994, there has been a great accumulation of knowledge on fighting obesity by facilitating pharmacological and nutritional strategies on the molecular level of the body weight control system. In particular, evidences are accumulating that particular food components affect our physiological function and gene expressions which are associated with body weight control. In this study, we review the four mechanisms for weight control and antiobesity functional agents such as HCA, L-carnitine, CLA, chitosan, calcium supplements capsaicin contained in red pepper, and oriental herbal mixture. We also describe about the efficacy and working mechanism of these functional agents on the basis of antiobesity mechanisms.

사군자탕가미방(四君子湯加味方)이 난소적출 폐경 병태 모델의 자궁 및 난소 기능에 미치는 영향

맹유숙 ( Yu Sook Maeng ),최민선 ( Min Sun Choi ),안인숙 ( In Suk Ahn ),김동일 ( Dong Il Kim ) 대한한방부인과학회 2012 大韓韓方婦人科學會誌 Vol.25 No.4

Objectives: The purpose of this study is to examine the effects of Sagunjatang -Gami(SGJT) on uterine and ovarian function in the ovariectomized rat postmenopause model. Methods: SGJT was administered in ovariectomized Wister albino female rats for three month. After that, uterine weight, uterine index, serum estradiol-17β levels and phosphorylation of ERK or AKT, and histological analysis of uterus were measured to assess the impact on uterine and ovarian function in ovariectomized rats. In addition, phosphorylation of ERα, ERK, AKT by SGJT in MDA-MB-231 cells were measured. To identify safety of SGJT, the cell cytoxicity in MDA-MB-231 cells and serum GOT, GPT levels were measured in ovariectomized rats. Results: The results were as follows. 1. SGJT decreased the viability of MDA-MB-231 cells in a dose-dependent manner. 2. The level of serum GOT, GPT in SGJT-treated group showed significant decrease in comparison with control group. 3. Phosphorylation of ERα, ERK, AKT by SGJT in MDA-MB-231 cells were increased. 4. Uterus index in SGJT-treated group showed significant increase in comparison with control group. The level of serum estradiol-17β in SGJT-treated group showed significant increase in comparison with control group. Phosphorylation of ERK or AKT by SGJT in the uterus of ovariectomized rats was increased significantly. 5. Uterus index and the level of serum estradiol-17β in SGJT-treated group increased at higher rates in comparison with estrogen-treated group. Conclusions: Taken together, we suggest that SGJT has been shown to be effective in preventing postmenopausal uterine and ovarian degeneration and curing postmenopausal low estrogen related symptoms.

경제와 여성 구두 굽 높이 변화의 관계

안인숙(In Sook Ahn) 한국복식학회 2015 服飾 Vol.65 No.7

This study is to investigate the relationships between heel height and macro-economic factors - recession and unemployment; and to analyze the time lags reflecting economic factors on heel height index using U.S. data. The life-history evolution theory was applied to propose the relationships studied. The data for the heel height measurements of women’s shoes - pump style only - were obtained from US Vogue fashion editorial sections on spring and fall editions from 1950 to 2014. I divided the heel height by the length of the shoes in order to standardize the data. Total of 1581 samples were used, and heel height data were aggregated to create a yearly average. To explore the relationships between macro-economic factors and heel height, this study used OLS of Stata 13 program. The main findings show that unemployment rates influenced heel height for three years in a positive direction. Furthermore, the effects of unemployment rate from two years ago on the current heel height were very close to being on a significant level.

3차원 바디 스캐너를 이용한 시판용 일체형 작업복 분석

안인숙(In Sook Ahn),이상윤(Sang Yun Lee) 한국복식학회 2018 服飾 Vol.68 No.4

폐기된 청바지를 활용한 생활용품 디자인 연구

안인숙(In Sook Ahn),김호경(Ho Kyung Kim) 한국복식학회 2015 服飾 Vol.65 No.1

Excessive spending and the ever-changing fashion trends lead to an increase in material production to meet consumers’ needs, which also in turn, increase the amount of industrial waste and many harmful pollutants. To address this problem, this study aimed to utilize discarded jeans’ parts, reconstructing them into edgy and functional designs for everyday products. Six pairs of discarded jeans were collected and were used to create six types of functional products -three types of baskets, a bag, a slipper, and a key-holder. The benefits of up-cycling outweigh recycling because it not only increases the recycling rate, but also decreases the amount of energy and cost, thereby increasing the efficiency in recreating new innovative products. These proposed up-cycling ideas will serve as a great alternative for consumers to actively participate in reducing carbon emission, water usage, and waste to landfill by utilizing used clothing. This will guide how consumers can extend the life of their used clothing, utilize recyclable items more thoroughly, and keep used clothing out of landfills.

애니메이션 영화를 이용한 초등학생의 영어 듣기 능력 향상 방안

안인숙(Ahn In Sook) 영상영어교육학회 2005 영상영어교육 (STEM journal) Vol.6 No.1

This study was designed to examine the effect of the English animation movies on listening ability to appeal to students in elementary school, and was aimed at finding new ways and means to teach English more effectively. Twenty six sixth-grade students, who were given the listening lessons with Toy Story 2, showed remarkable improvement of their listening comprehension. That of post- test (84.54) was higher (3.71) than the average of pre-test (80.83). There was significant difference in the significant level (p<.01). These students showed more interest toward English. The students showed a greater enthusiasm for English in the post-test. It would be helpful for teachers and students to use the English animation movies.

여성 스커트 길이 스타일 변화주기에 관한 연구 -1950년부터 2013년까지 Vogue 자료를 중심으로-

안인숙 ( In Sook Ahn ) 복식문화학회 2014 服飾文化硏究 Vol.22 No.4

The purpose of this study was to find whether hemline cycles exist and whether hemlines show greater within-year variability over time. Utilizing US Vogue data from 1950 to 2013 on hemline length of women`s daywear, total 2102 day-dresses or skirts on full fashion pictures were analyzed. The skirt length was divided by the total length of figure in the picture which was measured from shoulder to ankle. Aggregated yearly means smoothed by means of three-point moving averages were used to provide a better indication of the long-term direction of movement of the hemline. Within-year hemline variability was smoothed by the way of three-point moving average as well. The data showed five cycles on hemline change processes. The first cycle took 21 years from 1950 to 1971, which was the longest period and had the biggest hemline changes. The second cycle was the shortest from 1971 to 1977, in which hemline moved between below-knee length and midcalf. The hemline in the third cycle moved between midcalf and miniskirt. The third cycle took 16 years from 1977 to 1993. The forth was a short cycle from 1998 to 2001, and hemlines moved moderately between below-knee length and above-knee length. The fifth cycle has been on going since 2001, and the hemline has been getting longer after 2007. The within-year variability of hemlines was bigger in 1980s than previous years and was steadily increased.

국내 자동차 일체형 작업복 제품 조사 및 착의 기능성 평가

안인숙(In Sook Ahn),이상윤(Sang Yun Lee) 한국복식학회 2017 服飾 Vol.67 No.8

현대 패션에 나타난 IT패션융합 현상

안인숙 ( In Sook Ahn ) 중앙대학교 예술문화연구원(구 생활문화산업연구소) 2014 예술문화융합연구 Vol.2 No.-

The merge between fashion and IT industries indicates technological advances, that is accompanied by a trend that prioritizes human-centered elements and emotional attributes. This trend also indicates a bright future for the high value-added industries, which utilizes the convergence between digital and textile technologies. Currently, such technological merges are evident in areas such as sportswear, leisurewear, clothing for medical and healthcare practices, entertainment clothing, and protective safety wear. These types of wears emphasize functionality, and thus, entails integration of textiles with state-of-the-art electronic elements. The industry should move forward beyond the stage that merely focuses on materials and design. Rather, the fashion industry should take heed of the wide range of dimensions such as aesthetics, functionality, economics, creativity, orderliness, and human emotional attributes. Overall, the effort to broaden the application and communication areas should continue.

HHD Mice를 이용한 대장암세포유래 펩타이드 특이적 CD8⁺ T 세포의 입양전이

정헌순,안인숙,도형기,도명술,Jung, Hun-Soon,Ahn, In-Sook,Do, Hyung-Ki,Lemonnier, Francois A.,Tirosh, Boaz,Tzehoval, Esther,Vadai, Ezra,Eisenbach, Lea,Do, Myoung-Sool 대한면역학회 2004 Immune Network Vol.4 No.1

Background: 1-8D gene is a member of human 1-8 interferon inducible gene family and is shown to be overexpressed in fresh colon cancer tissues. Three peptides 1-6, 3-5 and 3-7 derived from 1-8D gene were shown to have immunogenicity against colon cancer. Methods: To study tumor immunotherapy of these peptides we established an adoptive transfer model. $D^{b-/-}{\times}{\beta}2$ microglobulin (${\beta}2m$) null mice transgenic for a chimeric HLA-A2.1/$D^b-{\beta}2m$ single chain (HHD mice) were immunized with irradiated peptide-loaded RMA-S/HHD/B7.1 transfectants. Spleens were removed after last immunization, and splenocytes were re-stimulated in vitro. Lymphocytes from vaccinated HHD mice were transferred together with IL-2 to the tumor bearing nude mice that were challenged S.C. with the HCT/HHD/B7 colon carcinoma cell line that was found to grow in these mice. Results: Peptide 3-5 was found to be highly effective in CTL activity. Adoptively transferred anti-peptide 3-5 cytolytic T lymphocytes caused significant retardation in tumor growth. Conclusion: This study shows that peptide 3-5 can be the most effective candidate for the vaccine of adoptive immunotherapy against colon cancer.