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혈액종양 : 식도암 환자에서 발생한 항이뇨 호르몬 부적절 분비 증후군 1예
이소연 ( So Yon Rhee ),신성호 ( Sung Ho Shin ),이재혁 ( Jae Hyuk Lee ),안재성 ( Jae Sung An ),도병주 ( Byong Joo Do ),장근두 ( Geun Doo Jang ),송헌호 ( Hun Ho Song ) 대한내과학회 2015 대한내과학회지 Vol.88 No.2
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) may be observed in various types of cancer, but is mainly seen in small-cell carcinoma. It can also be caused by several chemotherapeutic agents. However, it is a very rare phenomenon in esophageal cancer or its treatment. We report here on a case of SIADH related to esophageal cancer treatment. A 55-year-old man received chemoradiotherapy (CRT) for esophageal cancer. After receiving CRT for 5 days, he complained of nausea, dizziness, and general weakness, and his sodium level had dropped to 107 mEq/L. His volume status was clinically euvolemic and there were no edema or pigmentation. After hypertonic saline infusion, the sodium level increased and the symptoms improved. There have been several reports of SIADH associated with malignancies or chemotherapy agents. However, to the best of our knowledge, this is the first Korean case of SIADH associated with esophageal cancer that occurred after cisplatin treatment. (Korean J Med 2015;88:231-235)
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안재성 ( Jae Sung Ahn ),이소연 ( Soyon Rhee ),도병주 ( Byoung Joo Do ),박인영 ( In Young Park ),신성호 ( Sung Ho Shin ),이재혁 ( Jae Hyuk Lee ),송헌호 ( Hunho Song ) 대한내과학회 2015 대한내과학회지 Vol.88 No.6
Primary leiomyosarcoma rarely occurs in bone; when it occurs, it is more frequent in middle-aged individuals and frequently metastasizes to the lung. Here, we report a case of primary leiomyosarcoma of the femur in a 47-year-old woman who complained of pain in the left hip. The plain x-ray revealed an osteolytic lesion in the greater trochanter of the femur. The histopathological and immunohistochemical evaluation revealed a moderately differentiated leiomyosarcoma. Computed tomography of the chest and abdomen revealed no other potential primary lesions. The patient was diagnosed with primary leiomyosarcoma of the bone. Although surgical removal was recommended, the patient refused surgery. As an alternative, she was given radiotherapy and chemotherapy. No local progression or distant metastasis has been observed during the 4-year follow-up period.(Korean J Med 2015;88:724-727)
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