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편측성 Darier 병 극세포해리성 이각화성 표피모반?
송마가렛 ( Margaret Song ),서상희 ( Sang Hee Seo ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),오창근 ( Chang Keun Oh ),권경술 ( Kyung Sool Kwon ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.5
Darier`s disease is an uncommon genodermatosis, characterized by the symmetric eruption of keratotic papules, focal loss of epithelial adhesion and abnormal keratinization. A unilateral, or localized variant has been identified as a mosaic form, involving linear or ``zosteriform`` epidermal lesions with clinical and histological features of Darier`s disease. Some suggest that unilateral lesions should be classified as acantholytic dyskeratotic epidermal nevi, rather than localized Darier disease. A 17-year-old male presented with unilateral zosteriform distribution of brownish hyperkeratotic papules with ipsilateral v-notching of the thumb nail. A biopsy specimen revealed acantholysis, suprabasal cleft and multiple dyskeratotic cells. We report a case of unilateral Darier`s disease which further supports unilateral dermatologic manifestation as a variant of Darier`s disease. (Korean J Dermatol 2008;46(5):703∼706)
송마가렛 ( Margaret Song ),서상희 ( Sang Hee Seo ),정도상 ( Do Sang Jung ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),권경술 ( Kyung Sool Kwon ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.4
We present a patient with various features of oculo-auriculo-vertebral syndrome (OAVS), also known as Goldenhar`s syndrome. In general, multiple accessory tragi in a linear distribution from the preauricular skin to the mandible or to the lateral neck suggest a diagnosis of OAVS. However, in most cases, an accessory tragus is an isolated developmental defect without an associated congenital syndrome. A female infant presented with a solitary, skin colored, sessile papule on the right lower cheek, microtia, and ear deformity since birth. A biopsy specimen showed numerous irregularly spaced hair follicles with a prominent connective tissue framework in the subcutaneous fat, but without central cartilage. Multiple congenital anomalies, including ocular lipodermoid, sensorineural hearing loss, and vertebral deformity, were found on further evaluation. (Korean J Dermatol 2009;47(4):487~490)
안면부 기저세포암의 모즈 미세도식 수술 후Burow씨 식피술을 이용한 재건술
송마가렛 ( Margaret Song ),정도상 ( Do Sang Jung ),서상희 ( Sang Hee Seo ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),권경술 ( Kyung Sool Kwon ),오창근 ( Chang Keun Oh ) 대한피부과학회 2009 大韓皮膚科學會誌 Vol.47 No.2
Background: In reconstruction of facial defects, large defects or defects with insufficient skin laxity could pose a challenge. Burow`s graft is a modified full-thickness skin graft which utilizes adjacent skin as the donor site. Objective: To describe the surgical technique of Burow`s grafts and to report our experience with the postoperative cosmetic outcome. Methods: This is a retrospective review of 16 cases of basal cell carcinoma, reconstructed with Burow`s grafts after Mohs` micrographic surgery. Burow`s graft was performed in surgical defects which were too large for primary closure. Burow`s grafts were then placed on the remaining primary defects and sutured. The size of the tumor and postoperative surgical defects, local complications, and cosmetic outcomes were assessed. Results: The size of primary defects ranged from 0.9 to 3.5 cm (with a mean of 1.98 cm) in greatest diameter. Seven cases were located on the nose, 3 on the cheek, 2 on the ear, 2 on the temple, and one on the eyebrow and lower eyelid. During the follow-up period, partial graft necrosis occurred in 2 patients but there was no evidence of acute bleeding, hematoma, or infection. There was no tumor recurrence and most of the patients showed minimally discernable scarring with satisfactory aesthetic outcomes. Conclusion: Burow`s graft could be recognized as a useful reconstructive method in large skin defects and in areas with limited skin laxity. It provides an aesthetically pleasing result, and it is also simple and easy to perform. (Korean J Dermatol 2009;47(2):132∼139)