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서영우,차덕선,조윤애,김승현.Young-Woo Suh. MD. PhD. Deoksun Cha. MD. Yoonae A. Cho. MD. PhD. Seung-Hyun Kim. MD. PhD 대한안과학회 2011 대한안과학회지 Vol.52 No.4
Purpose: To investigate clinical characteristics of constant exotropia patients with a previous history of intermittent exotropia. Methods: Constant exotropia patients (CXT) with a previous history of intermittency, and intermittent exotropia patients (X [T]) who had undergone surgery for exotropia were included in the present study. Patching therapy of the fixating eye was performed for all patients. Surgical results, the effect of patching, lateral incomitancy, and suppression were retrospectively reviewed and compared between the 2 groups. Results: The number of CXT was 51 and X (T) was 84. The angles of deviation at the initial visit and at surgery were significantly larger in CXT. After 3 months of patching therapy, there was no difference between the 2 groups in the reduction of distant angle of deviation. However, the reduction of near angle of deviation was 0.29 ± 5.44 in CXT and 4.42 ± 6.26 Δ in X (T), which was significantly different (p = 0.04). Lateral incomitancy was observed in 7.8% of CXT and 34.5% of X (T) (p < 0.001). The angles of deviation at the final visit and surgical success rate were not different between the groups. Preoperative suppression at distant was found in 100% of CXT and 88.7% of X (T), and postoperative suppression was in 17.6% and 18.3%, respectively. Conclusions: The surgical success rate and postoperative suppression were not different between constant exotropia and intermittent exotropia. However, the frequency of lateral incomitancy and the response to the patching therapy was lower in constant exotropia. J Korean Ophthalmol Soc 2011;52(4):462-465
초음파 유화술시 발생하는 유리기에 대한 아스코르빈산의 각막 내피 보호 효과
서영우,오청훈,김효명,Young-Woo Suh,Chung-Hoon Oh,Hyo-Myung Kim 대한안과학회 2005 대한안과학회지 Vol.46 No.3
Purpose: To evaluate corneal endothelial protection effect of ascorbic acid (AA) at the most appropriate concentration, and determine the synergistic effect of glutathione in irrigation solution during phacoemulsification. Methods: Phacoemulsification was performed in the anterior chamber of 30 rabbit eyes for 5 minutes without damage to other ocular structures. Thirty rabbit eyes were divided into 6 groups, of 5 eyes each, according to the following irrigation solutions in phacoemulsification.: BSS? in group 1, BSS? with 1 mM AA in group 2, BSS Plus? in group 3, BSS Plus? with 0.1 mM AA in group 4, BSS Plus? with 1 mM AA in group 5 and BSS Plus? with 10 mM AA in group 6. Corneal endothelial loss was measured with specular microscopic photographies taken before and 1 week after surgery. Results: Postoperatively endothelial counts were reduced by 592.0±100.0, 275.9±51.9, 658.2±107.1, 466.3±88.6, 259.3±61.6 and 451.6±63.7 (mean cells/mm2±SD) in groups 1-6, respectively. Endothelial cells in group 2 were less reduced than in group 1 (P=0.009), but there was no difference between groups 2 and 5. Though the reduction of endothelial cells in groups 4, 5, and 6 were less than in group 3 (P<0.05), group 5 showed more significant endothelial protection effect than groups 4 and 6 (P=0.009, 0.009). Conclusions: AA in irrigation solution showed endothelial protection effect against free radicals during phacoemulsification, and 1 mM was the most effective concentration. Combination of glutathione with AA did not show any synergistic endothelial protection effect.
서영우,김균형,강수연,김성우,오재령,김효명,송종석,Young-Woo Suh,Kyun-Hyung Kim,Su-Yeon Kang,Seoung Woo Kim,Jae Ryung Oh,Hyo-Myung Kim,Jong-Suk Song 대한안과학회 2010 대한안과학회지 Vol.51 No.10
Purpose: To develop methods for the objective measurement of ocular fatigue. Methods: Fifteen patients were enrolled in the present study. Subjects performed visual tasks on a computer for one hour. A survey of ocular fatigue was conducted with a questionnaire. Tear break-up time, blinking rate, ocular protection index, conjunctival injection, maximal blinking interval, temperature of the ocular surface, and visual evoked potential were evaluated before and immediately after the task. Surface electromyography of the orbicularis oculi muscle was performed before and during the task. Results: The survey showed increases in subjective ocular fatigue in all subjects. Tear break-up time, ocular protection index and maximal blinking interval decreased, while temperature of the ocular surface increased after the task. Conjunctival injection showed a tendency to increase. Electromyography, and visual evoked potential did not change significantly. Conclusions: In the present study, tear break-up time, ocular protection index, maximal blinking interval, and temperature of the ocular surface changed as ocular fatigue increased. Therefore, these measures can be objectively used for the evaluation of ocular fatigue. J Korean Ophthalmol Soc 2010;51(10):1327-1332
서영우,김승현,이주연,조윤애,Young-Woo Suh,Seung-Hyun Kim,JuYeoun Lee,Yoon-Ae A,Cho 대한안과학회 2005 대한안과학회지 Vol.46 No.3
Purpose: To evaluate the influence of part-time patching therapy on the types of intermittent exotropia. Methods: Forty-four children with basic type intermittent exotropia and 26 with convergence insufficiency type, aged 4 to 12 years, were evaluated. At initial examination, the deviating angles were obtained at distant and near with the alternate prism cover test after correcting for refractive errors. The types of intermittent exotropia were classified based on the reference values of distant-near difference as follow. In the patients with distant angle more than 30 PD, the reference value of distant-near difference was 10 PD, whereas in the patients with distance angle less than 30 PD, the value was one third of the distant angle. Three-hour per day patching of the non-deviating eye was performed for 3 months, and the change in the types of intermittent exotropia was investigated. Results: At initial examination, mean deviating angles (PD) were 27.1±7.46 PD at distant, and 30.6±7.92 PD at near. After 3 months with 3-hours patching, the deviating angles were both reduced significantly to 25.9±9.10 PD at distant and 21.4±11.00 PD at near (p=0.005, <0.001 respectively). Fourteen patients (32%) of basic type were transformed to pseudodivergence excess type. Among the patients with basic type who showed no change in type, 9 (20%) showed a reduction of angles at both near and distant. Among the patients with convergence insufficiency type, 18 (69%) were converted to basic type and 2 (7%) to pseudodivergence excess type. Conclusions: Three-hour patching therapy converted the basic and convergence insufficiency type to the pseudodivergence excess and basic type in more than half of the intermittent exotropes.