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RISS 인기검색어
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- 저자 : 박희평 ( Hee Pyoung Park ) (검색결과 5 건)
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임상연구 : 측와위에서 수술 전 일측폐환기가 향후 수술 중 일측폐환기 시 동맥혈 산소화에 미치는 영향
박희평 ( Hee Pyoung Park ),전영태 ( Young Tae Jeon ),박상헌 ( Sang Hyun Park ),이석면 ( Seok Myeon Rhee ),오용석 ( Yong Seok Oh ),황정원 ( Jung Won Hwang ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.5
Background: There are a few reports with conflicting results regarding the potentiation of hypoxic pulmonary vasoconstriction (HPV) by repeated hypoxic challenges. The aim of this study was to determine if preoperative one lung ventilation (OLV) in the lateral position (LP) for a short time decreases the development of arterial hypoxemia and improves the level of arterial oxygenation via the potentiation of HPV in patients undergoing thoracic surgery with OLV. Methods: Forty patients were randomly divided into two groups according to presence or absence of preoperative OLV. Preoperative OLV in LP was achieved for 10 minutes with 100% O2 in group P (n = 20). Thereafter, the two lungs were again ventilated with 50% O2 until OLV with 100% O2 had been achieved. In group C (n = 20), the two lungs were continuously ventilated with 50% O2 until OLV with 100% O2 was achieved. The arterial blood samples were obtained 15 minutes after the two lung ventilation in the supine position (baseline) during preoperative OLV in LP, before pulmonary vein ligation, as well as before and after pulmonary artery ligation. The development of arterial hypoxemia (peripheral blood oxygen saturation in pulse oximetry < 95%) in patients undergoing thoracic surgery with OLV was also recorded. Results: Arterial hypoxemia during OLV was observed in 2 cases in group C and 3 cases in group P. There was a similar level of arterial oxygen tension during OLV between the two groups. Conclusions: This study showed that the preoperative OLV in LP for 10 minutes neither potentiated the HPV response during OLV nor decreased the frequency of arterial hypoxemia during OLV. (Korean J Anesthesiol 2006; 51: 568~72)
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Midazolam 전투약이 목표농도 조절방식으로 투여되는 Propofol과 Rocuronium 작용 발현에 미치는 영향
구의경 ( Eui Kyoung Goo ),정철희 ( Cheol Hee Jung ),김환희 ( Hwan Hee Kim ),소윤미 ( Yun Mi So ),나효석 ( Hyo Seok Na ),박희평 ( Hee Pyoung Park ),전영태 ( Young Tae Jeon ),황정원 ( Jung Won Hwang ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.4
Background: This clinical study was designed to evaluate the effect of midazolam as a premedication on the onset of propofol and rocuronium during propofol target-controlled infusion (TCI). Methods: Seventy four patients (ASA class I or II) were randomly allocated to receive either no premedication (control group) or premedication with 0.04 mg/kg intravenous midazolam (midazolam group). Anesthesia was induced and maintained with propofol TCI. Time from propofol injection to loss of consciousness (LOC) and estimated effect concentration at LOC were recorded. After LOC, rocuronium (0.6 mg/kg) was injected. We monitored the degree of neuromuscular blockade by acceleromyography. The following parameters were measured and compared between groups: Time from rocuronium injection to depression of twitch height below 25%, time to maximal depression of twitch height (defined as rocuronium onset time). Results: Systolic blood pressure before induction was lower in midazolam group (125±15 vs 135±20 mmHg), however, there was no difference in blood pressure at LOC between groups (111±16 vs 106±21 mmHg). In midazolam group, time to LOC in propofol TCI was shorter (63±22 vs. 203±118 sec) and estimated effect site concentration of propofol was significantly lower than control group (0.9±0.3 vs. 2.2±0.4 μl/ml). The onset time of rocuronium was not different between groups (120±39 vs. 137±42 sec). Conclusions: Midazolam pretreatment fastens the onset time of propofol and decreases the propofol requirement for LOC. However, it does not influence the onset of rocuronium. (Korean J Anesthesiol 2009;57:434∼7)
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자가조절 진정을 이용한 기관지 내시경술에서 Midazolam 전투여가 환자 만족도에 미치는 영향
권원경 ( Won Kyoung Kwon ),최은수 ( Eun Su Choi ),김지영 ( Ji Young Kim ),박상리 ( Sang Ri Park ),나효석 ( Hyo Seok Na ),박상헌 ( Sang Hyun Park ),박희평 ( Hee Pyoung Park ),전영태 ( Young Tae Jeon ),황정원 ( Jung Won Hwang ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.1
Background: Patient-controlled sedation (PCS) with propofol is a safe and effective method of attenuating discomfort during fiberoptic bronchoscopy. The purpose was to evaluate the usefulness of midazolam in addition to PCS for fiberoptic bronchoscopy. Methods: We randomly assigned 155 patients undergoing diagnostic bronchoscopy to two groups. Group M (n=79) received 0.03 mg/kg of midazolam for premedication while group P (n=76) received a loading dose (0.05 ml/kg) of PCS solution composed of 200 mg (20 ml) of propofol and 1 mg (2 ml) of alfentanil. Both groups received the PCS solution 0.2 ml/kg/hr with a bolus of 1 ml and a lockout time of 1 min. Vital signs, pulmonologist satisfaction, patient satisfaction and amnesia were evaluated. Results: After the insertion of the bronchoscope, there was a slight decrease of SpO2 and an increase of blood pressure and heart rate in both groups with no significant differences between the two groups. The group P required more bolus injections (1.6±1.7 in the group M vs 2.5±2.2 in group P; P<0.05). There was no difference in the satisfaction of pulmonologists, but the satisfaction of patients was higher in the group M (P<0.05). More patients in the group P (93%) remembered the procedure than in the group M (70%) (P<0.05). Conclusions: PCS is an effective method for sedating patients undergoing fiberoptic bronchoscopy and midazolam provides more patient satisfaction and amnesia. (Korean J Anesthesiol 2009;56:1~5)
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박희평,오용석 대한정맥마취학회 2002 정맥마취 Vol.6 No.1
Background: Pain is the most important factor responsible for ineffective ventilation and cough in patients undergoing thoracotomy. Intravenous patient-controlled analgesia (PCA) is widely used for postoperative pain control. Opoid contained PCA is likely to increase the incidence of postoperative nausea and vomiting (PONV). We studied the effect of PCA on patients with thoracotomy. Method: After consciousness was recovered from anesthetic emergence, PCA was connected to 85 patients in postanesthetic recovery room or intensive care unit. The PCA regimen was composed of ketorolac, fentanyl and morphine, and the doses of drugs was adjusted according to patient's age and sex. The PCA was set at basal rate 0.5 ml/hr, bolus dose 1 ml, lockout time 10 min. The incidence and severity of nausea, vomiting, sedation, pain and other side effects were assessed at 1, 4, 8, 12, 18, 24, 36, 48, 60 and 72 hr postoperatively. Result: The highest VAS score was 5.7 on 1hr postoperatively. As time went by, VAS score decreased to 3.1. PONV occurred in 31 patients. The incidence of PONV is higher in female than in male (P < 0.01). Sedation occurred in 40 patients, and drowsy state is most common. Both pruritus and urinary retention occurred in 12 patients respectively. Respiratory depression below 8 breaths/min was not observed in all subjects. Conclusion: The use of PCA on patients undergoing thoracotomy represented satisfactory pain relief except immediate postoperative period. Side effects, such as PONV and sedation, were successfully treated by supportive care and temporary hold of infusion of PCA.
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