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장내 소화 효소 활성 저해를 통한 섭취 영양소의 흡수 억제와 이를 이용한 비만 개선용 식이조성물의 개발
윤유식,박윤신,홍정미,최선미,이흥석,홍성길 대한영양사협회 2002 대한영양사협회 학술지 Vol.8 No.2
In this study, we report a new food additive as a natural herbal extract against lipid digestion enzymes for the regulation of fatty acid absorption and weight control. The Water extracts of Platycodon grandiflorum and Solanum melongena inhibited lipase activity in vitro and decreased triglyceride and serum total cholesterol concentration in mouse fed lipid emulsion. Twenty three volunteers were subjected to the intake of the herbal extract plus the egg yolk IgY that inhibits carbohydrate digestion enzymes in gut for 50 days. In the average, the treated subjects lost 1.96㎏ of body weight and 3.4㎏ of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of natural herbal extract and egg yolk IgY improved the obesity by decreasing body weight and body fat mass.