Inhibitory Effect of Dendrobium moniliforme on NO and IL-$1{\beta}$ Production in LPS-stimulated Macrophages

박가영,배창환,박순영,김지희,고우신,김영희,Park, Ga-Young,Bae, Chang-Hwan,Park, Sun-Young,Kim, Ji-Hee,Ko, Woo-Shin,Kim, Young-Hee The Society of Korean Medicine Ophthalmology 2009 한방안이비인후피부과학회지 Vol.22 No.3

석곡은 난초과의 여러해살이풀 Dendrobium moniliforme의 지상부를 건조한 것으로 예로부터 양위생진(養胃生津), 자음제열(滋陰除熱) 등의 효능이 있어 해열, 진통의 작용과 위액분비 촉진, 혈압강하의 작용이 있는 것으로 알려져 있다. 본 연구에서는 석곡의 항염증 작용 기전을 알아보기 위하여 석곡 열수추출물을 대식세포주에 처리하여 NO 및 IL-$1{\beta}$의 생성에 미치는 영향을 조사하였다. LPS로 자극된 대식세포주 RAW264.7 세포에서 석곡은 NO 및 IL-$1{\beta}$ 생성과 iNOS 단백질 발현을 저해하였으며, LPS에 의해서 활성화되는 ERK, p38, JNK 효소의 활성을 현저히 억제하였다. 이 결과들로 보아 석곡의 항염증 작용이 MAPK 활성 저해로 인한 NO 및 IL-$1{\beta}$ 생성의 억제 때문인 것으로 사료된다.

12세 여아에게서 활동성 폐결핵에 동반된 장결핵 1례

박가영,박재영,김창휘,곽정자,박재옥,Park, Ga Young,Park, Jae Young,Kim, Chang Hwi,Kwak, Jeong Ja,Park, Jae Ock 대한소아감염학회 2013 Pediatric Infection and Vaccine Vol.20 No.3

결핵은 다양한 임상양상을 보이는 감염병으로 과거에 비해 많이 감소하였고 소아 결핵도 점차 줄어들고 있으나 여전히 중요한 감염병이다. 소아의 결핵은 성인과는 다른 임상적 특징을 가지며 폐외 결핵의 빈도가 성인보다 높고, 청소년의 결핵은 결핵균 감염에서 실제 질병으로 발전될 위험이 크다. 폐외 결핵 중 장결핵은 증상이 비특이적이고 다양하여 진단이 늦어질 경우 사망률 및 이환율이 높아질 수 있다. 크론병 또는 만성적인 소화기 질환과의 감별이 중요하며, 최근 대장 내시경의 발달로 감별 진단이 용이해지고 있다. 저자들은 6개월간 지속된 설사와 복통, 체중 감소와 간헐적이고 반복적인 $37.5-38^{\circ}C$의 발열로 내원한 12세 여아에게서 대장 내시경 검사를 하여 시행한 생검 조직의 PCR 검사와 조직학적 소견으로 장결핵을 진단하였고, 연이어 촬영한 흉부 방사선 상 활동성 폐결핵으로 진단되어 11개월간의 항결핵제 치료로 완치된 증례를 경험하였다. Intestinal tuberculosis (TB) is presented with nonspecific and variable clinical manifestations such as abdominal pain, diarrhea, fever and weight loss. Diagnosis of tuberculous enteritis may be missed or confused with many other chronic gastrointestinal disorders such as the Crohn disease and intestinal neoplasms. The diagnosis should be based on careful clinical evaluations, such as extra-intestinal signs and colonoscopic and histologic findings. Newer techniques such as PCR tests from the specimens through colonoscopic biopsy may be helpful to confirm diagnosis of tuberculous enteritis. The treatment regimens for pulmonary tuberculosis are generally effective for tuberculous enteritis as well. If not treated early, the prognosis of intestinal tuberculosis is poor. We report a case of tuberculous enteritis diagnosed by colonoscopic biopsy and TB PCR which was presented with diarrhea, abdominal pain, intermittent fever and weight loss in a 12-year-old girl with active pulmonary tuberculosis. The patient was treated successfully with antituberculosis agents for 11 months without any complications.

중고거래 온라인 플랫폼의 보안을 위한 사용자 경험 연구 -당근마켓, 번개장터 중심으로-

박가영,김승인,Park, Ga-Young,Kim, Seung-In 한국디지털정책학회 2021 디지털융복합연구 Vol.19 No.7

The purpose is to measure user experience in security-related services, focusing on Danggeun Market and Bungae Jangter, which are representative services in Korea among online trading of used goods. Using mobile applications, qualitative and quantitative research by conducting task experiments and surveys and in-depth interviews. As a result of the study, active interfaces are needed to make it easier for users to recognize safety and security services within current used trading platforms, a secure settlement method that benefits sellers, and services being provided to enhance security also need to consider graphical elements. This study is expected to help the continued development of safe used trading platforms considering security aspects on C2C-type platforms where buyers become sellers. 본 연구는 중고거래 온라인 플랫폼 중 국내 대표 서비스인 당근마켓과 번개장터를 중심으로 보안 관련 서비스에 관한 사용자 경험을 측정하는 데 목적이 있다. 모바일 애플리케이션을 이용한 태스크 실험과 설문조사 및 심층인터뷰를 진행하여 정성적, 정량적 연구를 진행했다. 연구 결과 현 중고거래 플랫폼 내의 안전성과 보안성 관련 서비스를 사용자들이 더욱더 쉽게 인지 할 수 있도록 적극적인 인터페이스가 필요하고, 판매자에게도 이익 실현이 이루어지는 거래방식이 필요하며, 보안성을 강화하기 위해 제공되고 있는 서비스 또한 지속해서 그래픽(Graphic) 요소의 시인성을 높여야 한다. 이 연구는 구매자가 판매자가 되는 C2C 형태의 플랫폼에서 보안성 측면을 고려한 안전한 중고거래 플랫폼의 지속적인 발전에 도움이 될 것으로 기대한다.

새로운 유형을 포함한 갈락토스혈증의 이해

박가영,홍용희,Ga Young Park,Yong Hee Hong 대한유전성대사질환학회 2023 대한유전성대사질환학회지 Vol.23 No.2

Galactosemia is an inborn error disorder of carbohydrate metabolism, caused by metabolic disturbances at various stages of the Leloir pathway. In patients with galactosemia, accurate diagnosis and appropriate care are essential to avoid complications and unnecessary treatments. And a careful differential diagnosis of the type of galactosemia is crucial. Even with an appropriate galactose-restricted diet, long-term complications may occur, especially in patients with classic galactosemia. So new treatment options are being developed. In this review, we will review the new symptoms of each subtype that have been reported recently and GALM (Galactose mutarotase) deficiency, a new form of galactosemia, and treatment policies according to recent guidelines.

조선시대 갑주 유물의 감정을 위한 현황파악과 시대구분

박가영(Ga Young Park) 한국복식학회 2008 服飾 Vol.58 No.5

조선시대 군사복식의 디자인과 조형적 특성

박가영 ( Park Ga-young ) 한국디자인트렌드학회 2014 한국디자인포럼 Vol.45 No.-

역사적으로 군사복식이 패션디자인에 미친 영향은 상당히 컸기에 본 연구에서는 조선시대 군사복식의 유물ㆍ문헌ㆍ회화자료를 가지고 디자인을 분석하고 조형적 특성을 추출함으로써 한국적 패션디자인 개발에 기여하고자 한다. 갑주(甲?)는 트임으로 활동성을 높이고 두정 배열 속에 상징성이 있었으며 용과 봉황문양을 최고의 공예기술로 장식하였고 오방색(五方色)을 기본으로 전개한 디자인이다. 군복(軍服)은 트임이 많아서 활동적이고 가변적인 디자인이며 다목적의 기능성 의복으로 직물 문양과 오방색의 배색을 통해 장식성을 추구했다. 융복(戎服)은 치마주름으로 활동공간을 확보하고 소매가 탈착가능한 가변적 디자인이며, 주립의 재료와 장식으로 장식성이 강하였다. 방령(方領)과 전장후단(前長後短)의 옷을 중심으로 본 기타 무관복식은 디자인의 변화 폭이 넓은 의복이고 직물로 보아 화려함을 과시했던 장식적인 디자인이었다. 조형적 특성은 다음의 네 가지로 종합할 수 있다. 첫째, 구조적 활동성은 군사복식의 필수조건으로서 동작을 방해하지 않고 활동성을 높이기 위한 구조이다. 둘째, 가변적 기능성은 형태나 용도를 바꾸어 다른 기능을 수행하는 특성이다. 셋째, 심미적 장식성은 장군과 군사의 대외적 위용을 높이기 위해 필요한 요소이다. 넷째, 사회적 상징성은 오방색으로 소속부대를 표현하는 복식과 주술적 상징 의미를 담은 두정의 배열에서 발견되었다. Military costumes have long had a strong influence on fashion design. The purpose of this study is to analyze the design and identify the characteristics of military costumes in the Joseon dynasty to adapt these for Korean fashion design. For this reason, documentary records, paintings and relics were used as research material. Armor design provided increased motional flexibility through slits and the arrangement of rivets was symbolic. Decorations included images like dragons and the phoenix, and were developed based on five-elements color. Gunbok was active wear because of its various slits and variable design. It was multipurpose functional clothing, pursued through decorative patterns and the five-elements colors of fabric. Yungbok secured an activity space via skirt pleats, and featured a variable design with detachable sleeves. The hat was gorgeously decorative thanks to its material and ornaments. Clothes with a squared neckline or a shorter back had diverse designs and were showy items. The analysis of the formative characteristics is as follows: First, structural activity, an indispensable condition, is the structure provided for enhancing the activity. Second, variable functionality is the characteristic of providing different functions to change the type and purpose. Third, decorative aesthetics aim to increase the external grandeur of military generals and soldiers. Fourth, social symbolism was found in the costume`s expression of the regiment through the five-elements colors, and the arrangement of rivets, which had shamanistic symbolism.

조선 후기 면갑(綿甲) 유물 분석

박가영(Ga Young Park),송미경(Mi Kyung Song) 한국복식학회 2013 服飾 Vol.63 No.4

The cotton fabric armour for lower class soldiers can be found from the historical records of the mid-Joseon Korea. And the records show that the form and the structure of the armour was modified in the late 19th century in order to provide better protection from gunshots for the soldiers in the midst of the invasions from the West. This is a survey and research of the only artifact of the cotton fabric armour remaining in Korea - for its form, dimensions, and design. Using the historical records as reference, we can confirm the structure and characteristics of the cotton fabric armour of the Joseon period. This cotton fabric armour, preserved in National Museum of Korea, is a vest-type armour made of 30 layers of cotton. On the right shoulder, there is a button for tying knots and strings were tied under both armpits. On the surface of the cotton fabric armour there were some characters and patterns stamped in black. Presently, this artifact in Korea is the only specimen relic of its sort, but there are some other related relics in foreign countries including helmets and belts. Continuous researches would help extend the scope of armour study beyond the traditional researches that only focuses on the armours of the officials, thus helping us to understand the military costumes in traditional Korea.

국내 창의적 교육환경 연구 동향 분석

박가영(Park, Ga Young),이정민(Lee, Jeongmin) 한국창의력교육학회 2021 창의력교육연구 Vol.21 No.1

본 연구의 목적은 국내에서 진행된 초중고 대상 창의적인 교육환경 연구 동향을 분석하고 향후 연구 및 설계 시사점을 제공하는 것이다. 이를 위해 국내 학술지 데이터베이스(RISS)를 대상으로 2011년 1월부터 2020년 12월까지 게재된 논문 대상 ‘초중고’, ‘창의적인 교육환경’을 중심어로 1차 검색을 하고, 창의적인 교육환경과 관련된 논문 중 학위 논문, 특정 교과와 관련된 논문을 제외하여 2차적으로 추출하였다. 최종 선정된 42개의 논문을 연도별, 학술지별, 연구내용별, 연구방법별, 측정변인별, 측정도구별로 분석한 결과는 다음과 같다. 창의적인 교육환경 연구는 2015년에 가장 많은 연구가 진행되었으며, 학교환경과 가정환경이 모두 연구되었으나, 또래환경이나 물리적 환경 측면에서 연구가 상대적으로 부족하였다. 또, 학교급별로는 초등, 중등, 고등 순으로 연구가 많이 진행되었고, 연구방법으로는 양적연구가 많이 이루어졌다. 측정변인 분석에서 독립변인으로는 ‘창의적 가정환경’과 ‘창의적 학교환경’이 가장 많이 분석되었으며, 종속변인으로는 ‘창의성’이 가장 많았다. 측정도구는 특정한 동향이 보이지 않고, 연구자가 필요에 따라 사용하였다. 본 연구결과를 토대로 초중고 대상 국내 창의적인 교육환경 연구 및 환경설계에 대한 시사점을 제안하였다. The purpose of this study is to analyze the recent trends in the research of the creative educational environment in Korea. The subjects of the analysis are all journal articles published from 2011 to 2020. The primary search was conducted based on ‘elementary and secondary students’, ‘creative education environment’. Second, the dissertation and articles with the specific subject were excluded. The results were as follow: first, the largest number of research has been conducted in 2015. Both school and home environments have been studied, but there was a lack of research about peer and physical environments. Second, research was conducted most frequently in elementary school followed by middle, and high school in the respective order. Third, quantitative research has been conducted at most and ‘creative family environment’ and ‘creative school environment’ were chosen most frequently as the independent variable and ‘creativity’ was chosen most frequently as the dependent variable. Fourth, no specific measurement tool trends were found. Based on these findings, this study suggests research and practical implications for future research on creative educational environment.

『국장도감의궤』를 통해서 본 조선시대 갑주

박가영(Ga young Park) 아시아민족조형학회 2020 아시아민족조형학보 Vol.21 No.-

In the Joseon Dynasty, when people died, burial items were put in tombs along with their bodies in order to make the space after death. This is called myeong-gi, which are grave goods consist with everyday items, musical instruments, weapons, and wooden dolls. 『Gukjang Dogam Uigwe』 is a document that records the procedure when a king or queen died. Armor and helmets were also included in the list of grave goods in the king"s tomb. Therefore I studied Uigwe, Annals and liturgy. The armor and helmet used as the royal tombs were made of paper, leather, wood, and silk knots. So it rotted in the ground and there are no relics left to this day. In the early Joseon Dynasty, there was a system to bury armor and helmet in the king"s tomb. At first, only a list was written in Uigwe, but as the system was improved, materials and production methods were explained. In the late Joseon Dynasty, colored paintings, specifications, materials, and manufacturing methods were also recorded. In some cases, records had been copied from the previous one, so the actual situation was different. There is also information on craftsmen who make armors in 『Gukjang Dogam Uigwe』. We can know the name, organization, and name of the craftsman who makes the armors. The myeong-gi is the same shape as usual, but it was made small and coarsely to 1/5. The armor of 『Gukjang Dogam Uigwe of Jeongjo』 reflects the structure and characteristics of the armor at the time. On the other hand, if you look at the helmet doctrine, the basic structure is the same as that of the early Joseon Dynasty, but the details and proportions are exaggerated and distorted.

조선시대 군사복식의 홍색 상모(象毛)

박가영(Park, Ga Young) 아시아민족조형학회 2017 아시아민족조형학보 Vol.18 No.-

Sangmo(象毛) is a red hair hanging on the top of a helmet or military hat which is called jeollip(戰笠). In the literal meaning, sangmo is the hair of the elephant. But the actual material does not match the name. Therefore, the purpose of this study is to reveal the change of the name, material and concrete methods of production. Research data include historical documents, paintings and relics of the Joseon Dynasty. Sangmo means the decoration of the top of the helmet with feather or fur. This tradition had been both in China and Korea, but they were called yi in China and Sangmo in Korea. It was used to decorate various places such as military-related things, such as weapons, flags and ceremonial equipment, harnessry, musical instruments and costumes. In the military costume, sangmo is a symbol of the military officer, it distinguishes from the civil official. In the former period of the Joseon dynasty, there was a lot of difficulty because they were totally dependent on Chinese imports. In the latter period of the Joseon dynasty, sangmo was gradually replaced with domestic material which reddish dyed the white horse"s mane or tail. There were differences in how to attach the sangmo to the helmet and the jeollip. Sangmo was divided into small amount and was placed evenly by 360 degrees for the helmets, or it was bundled together and hanged for the jeollip.