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      • SCOPUSKCI등재

        유륜절개 접근법을 이용한 유방 축소술 : 중심피판경과 하부진피피판경의 비교

        한상훈,조종한,이상민,남상재 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.4

        After the introduction of the central parenchymal pedicle by Hester(1985) and the round-block technique by Benelli (1988), several variations of periareolar reduction mammoplasty have been used by many authors. Periareolar reduction mammoplasty is a less aggressive procedure than traditional techniques and it produces less conspicuous periareolar scars while maintaining an acceptable overall result. We experienced 120 cases (60 patients) of periareolar reduction mammoplasty during the period from May 1994 to February 1998. We present the analysis of 60 cases of periareolar reduction mammoplasty. Periareolar reduction mammoplasty utilizing central parenchymal pedicle was performed in the first 40 patients, while a procedure utilizing the inferior dermal pedicle was done in the next 20 cases consecutively. The range of follow-up was from 1 to 5 years. Complications such as nipple areolar complex necrosis and sensory changes were reduced when the inferior dermal pedicle used. There were 5 cases of nipple areolar complex necrosis and sensory changes were reduced when the inferior dermal pedicle used. There were 5 cases of nipple areolar complex necrosis (6.2%), including 1 case of near total necrosis in cases utilizing the central parenchymal pedicle. But in the technique using inferior dermal pedicle, there was no skin flap necrosis. The central parenchymal pedicle technique has several advantages such as a wide operation field permitting complete breast contouring and better mobility of the remaining breast tissue. However, inferior dermal pedicle technique has relative superiority over central parenchymal pedicle technique in terms of anatomical rationale, as well as in the rate of complications without causing limitations in breast mobility for contouring. Such complications as nipple areolar complex necrosis, skin flap necrosis and sensory change of nipple were reduced when the inferior dermal pedicle technique was used. It is much easier to preserve the 4th intercostal nerve to the nipple anatomically. Periareolar reduction mammoplasty utilizing the inferior dermal pedicle is thought to be a reliable, reproducible method.

      • Streptozotocin 誘發 過血糖症에 對한 實驗的 硏究

        南相在,申仁澈 한양대학교 의과대학 1988 한양의대 학술지 Vol.8 No.1

        Recently, corresponding to the lengthening of our life span, obesity which predisposes a person to diabetes mellitus have gradually been increased as well as the number of diabetes. Therefore, diabetes mellitus has been one of the most important problems in modern medical science. This study was conducted to ellucidate the effects of nicotinamide, nicotinic acid, L-cysteine, tolbutamide, diazoxide, D-glucose, D-mannose, 3-0-methyl-D-glucose and 2-deoxy-D-glucose on streptozotocin-induced diabetic mice. All drugs except streptozotocin dissolved in normal saline were injected intraperitoneally. Streptozotocin dissolved in acidified citrate buffer (pH4.5) was immediately injected intraperitoneally. Serum blood glucose level was determined 48 hours later. The results obtained from this study were as follows: 1. Serum glucose levels were elevated to 2 hours after administration of streptozotocin and decreasedto 10 hours after administration of streptozotocin. Serum glucose levels were elevated from 10 hours after administration of streptozotocin and maximum serum glucose level was achieved in 24 hours after admunistration of streptozotocin (430±31 mg/dl) and maintained the elevated state. 2. Nicotinamide protected almost completely against streptozotocin-induced hyperglycemia (92% inhibition of serum glucose levels in streptozotocin administered group). 3. 2-deoxy-D-glucose protected partially (67% inhibition of serum glucose levels in streptozotocin administred group) and 3-O-methyl-D-glucose protected almost completely against streptozotocin-induced hyperglycemia (97% inhibition of serum glucose levels in streptozotocin administered group). 4. 3-O-methyl-D-glucose and 2-deoxy-D-glucose were additive in teh portection against streptozotocin-induced hyperglycemia. 5. D-glucose, D-mannose, tolbutamide, diazoxide, L-cysteine and nicotinic acid did not protected the streptozotoin-induced hyperglycemia.

      • Vibrio 균 증식에 있어서 sodium-citrate 의 영향

        남상재,이강순 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

        The efficiency of selective isolation of V. vulnificus with current various agar plate media seemed to be significantly poor. So far, TCBS agar been most widely used for Vibrio species. The fact that several ingredients of TCBS agar inhibit growth of other contaminated organisms and ultimately enhance selective growth of Vibrio species could also inhibit Vibrio vulnificus should not be oversighted. Moreover differentiation between V. vulnificus and V. parahaemolyticus by morphology of colony grown on TCBS found to be quietly difficult. On these regards, the effect of each ingredient of TCBS agar including sodium citrate on the growth of V. vulnificus was needed to examine carefully in order to develop a better selective medium for V. vulnificus. A good many characteristics could be found through this experiment and these data could be applied for developing new medium. 1. V. vulnificus once transformed from opaque colony to translucent colony by given growth condition (in broth culture) was never changed 2. The growth of V. vulnificus appeared to be inhibited on agar plate medium by addition of low concentration of sodium citrate. The more concentration of sodium citrate was in medium, the poorer growth of V. vulnificus was observed. 3. Ferric ammonium citrate alone did not affect the growth of V. vulnificus. 4. Ferric nitrate and sodium thiosulfate markedly inhibited the growth of V. vulnificus. Conclusively, for the purpose of the growth of V. vulnificus there should be some modification of ingredients of TCBS agar or a newly designed medium other than TCBS agar, especially in case of V. vulnificus.

      • KCI등재

        수직절개식 유방축소수술의 새 도안

        심형보,남상재 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.2

        Although the technique of vertical reduction mammaplasty has gained major popularity, it is difficult to perform and has the steep learning curve. The authors present a modification of the standard Lejour vertical mammaplasty that simplify the design and make it more reliable and easy to perform. We simplified the design by discarding the Mosque dome. From March 2000 to March 2004, we performed this technique for 40 patients with breast hypertrophy. The apex of the design was marked at the anterior projection of the inframammary fold. After resection of the breast tissue, the medial and lateral pillars were approximated. Then a new nipple- areola position was determined at 4.0-5.0cm from a new inframammary fold. The range of resection amount of breast tissues was from 150 to 750 gram. Most of the patients were satisfied with the results. There was no permanent sensory loss and nipple areola skin necrosis. But there was 1 case of hematoma on the first day after the operation. This technique presents several advantages. It allows shaping and projection without compromising the future nipple position and makes it easier to remove an excessive skin around the areolae. And it may be comfortable to adjust the position of the nipple at the end of the procedure. We believe that this modification helps to improve the results of the vertical reduction mammaplasty.

      • KCI등재

        확장성(더블루멘) 보형물을 이용한 유방확대술

        심형보,남상재,윤상엽 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.4

        Ideal results of augmentation mammaplasty consist of symmetry, natural shape, soft feeling and inconspicuous scar. In addition, patient's preferences about size and shape should be included. Static implants could not perfectly satisfy patients' desires for size and shape, but expandable implants enable to change the volume after the operation. From September 2001 to September 2004, 76 patients(150 breasts) underwent breast augmentation using permanent expandable implant. The procedure was unilateral in 2 women and bilateral in 74 women. Age ranged from 19 to 50 years(mean, 29 years). Fifty nine patients underwent simple augmentation mammaplasty, 7 patients were corrected of their severe asymmetry, 2 patients with the congenital breast deformity underwent mammaplasty using this, and 2 patients who had undergone unilateral mastectomy were reconstructed of their breasts using expandable implant. There were no definite complications such as capsular contracture, implant rupture, asymmetry. And there reported little dissatisfaction about the size. The permanent expandable implants might be good alternatives in cases of ordinary breast augmentation as well as tissue deficient patients, asymmetry, congenital anomaly, and breast reconstruction.

      • KCI등재

        유두이식술을 이용한 유방축소술

        심형보,윤상엽,남상재 대한성형외과학회 2007 Archives of Plastic Surgery Vol.34 No.1

        Purpose: Free nipple graft reduction mammaplasty is a simple and effective way to reduce huge breasts. However, this technique is frequently criticized for producing poor projection and hypopigmentation of the nipple areola complex(NAC). Methods: Sixty three patients(126 breasts) underwent the procedure from 1998 to 2005. Authors' method is similar with the modified Gradinger's technique except the keyhole pattern. After skin flap closing, the position of NAC is determined considering symmetry. The NAC is initially harvested and then resection of the breast followed, leaving a deepithelized inferior parenchymal pedicle(5×5cm). The upper point of inferior pedicle is sutured to the fascia of the pectoralis to produce the upper bulge. The nipple is replaced as a free and composite graft.Results: An average of 823grams of breast tissue per breast was removed. There was no major complications. All grafted nipples showed long lasting projection. And also, all NAC eventually regained their normal color except for 3 patients who needed medical tattoos. The overall results were good and patient satisfactory score was high. Conclusion: This useful technique greatly enhances long lasting projection and recovers nipple color.

      • KCI등재

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