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BV-2 microglia 세포주에서 저산소증의 유전자 발현에 대한 마이크로어레이 분석
김범식,서정철 대한침구의학회 2003 대한침구의학회지 Vol.20 No.4
BV-2 microglia 세포주에서 저산소증의 유전자 발현에 대한 마이크로어레이 분석김범식, 서정철*고황의학연구소, 경산대학교 한의과대학 침구경혈학교실*
김범식 한국형사판례연구회 2018 刑事判例硏究 Vol.26 No.-
Forfeiture is a property punishment that deprives a crime-related property for the purpose of preventing the repetition of a crime or preventing it from profiting from the crime. In addition, Confiscation is a Judicial disposition to pay for the whole or part of the forfeitured object if it can not be forfeitured. Article 48 of the Korean Penal Code stipulates forfeiture and confiscation, and stipulates arbitrary. However, Article 134 of the Criminal Code (money to be paid to a bribe or bribe received by a criminal or a third person who knows the criminal in bribery), Article 206 of the Criminal Code (opium, opium, morphine), Article 357 (3) of the Penal Code (the property acquired by the criminal) and many special laws require forfeiture and confiscation as essential. In regard to such general forfeiture and confiscation, the Supreme Court refers to the forfeiture and confiscation in some special act as ‘disciplinary forfeiture and confiscation’ for the purpose of punishing without aiming at the deprivation of profits in light of the purpose of the legislation and the purpose of the legislation. and in the case of ‘disciplinary forfeiture and confiscation’, it acknowledges the collective responsibility of confiscation. In this article, I will review critically on what the Supreme Court has called ‘disciplinary confiscation’ for the forfeiture and confiscation of foreign exchange transaction act, and examine the problems of collective responsibility of confiscation.
김범식,강희재,서순주,박남석 한국진공학회 2016 Applied Science and Convergence Technology Vol.25 No.2
The structural and the electronic properties of pentacene on modified Si (001) were investigated using scanning tunneling microscopy (STM), atomic force microscopy (AFM) and ultraviolet photoelectron spectroscopy (UPS). Dodecane was used to modify Si (001) substrates and then pentacene was deposited on dodecane/Si (001). Our STM results show a uniform distribution of aggregated dodecane molecules all over the clean Si (001). The surface structure of pentacene on dodecaene/Si (001) examined by AFM is analogous to that of pentacene on SiO2. The UPS data showed that the work function of pentacene on clean Si (001) and pentacene on modified Si (001) with dodecane was 6.41 and 5.57 eV, respectively. Our results prove that dodecane results in the work function difference between pentacene on clean Si (001) and pentacene on dodecane/Si (001).
김범식,이정운,박민용 한국경영과학회 1998 한국경영과학회 학술대회논문집 Vol.- No.1
본 연구는 VDU (Visual Display Unit)화면 설계시 사용자의 시각탐색 형태를 파악하여 정보 전달의 효율성을 높이기 위한 연구이다. 본 연구는 현재 8명의 피실험자를 대상으로 하여 VDU 화면의 분할 정도와 제시되는 정보의 종류에 따른 영향을 관찰하였으며, 이때 화면의 분할 수는 1, 4, 9, 16의 네 수준으로, 제시되는 정보의 종류는 text와 graphic의 두 가지 형태로 하였다. 각 피실험자가 모든 실험조건에 대하여 실험에 임하는 Within-Subject design을 사용하였으며 이때 나타날 수 있는 피실험자의 carry-over effects는 라틴방격법을 사용하여 교략시켰다. 피실험자의 시각 탐색 형태를 기록하고 분석하기 위해서 최대 0.1。의 해상도를 갖는 Eye-Tracking System을 사용하였다. Eye-Tracking System을 통하여 수집 기록된 피실험자의 시각 탐색 정보는 FAST(Automated Fixations Analysis System)을 거쳐 분석을 원하는 영역들에 대한 시각 탐색순서, 빈도, 시간의 형태로 변환되며 이를 바탕으로 VDU 화면상에 제시되는 정보 형태와 VDU 화면의 공간적 배치간의 상관관계를 분석하였다. 실험을 통하여 피실험자의 시각탐색 형태를 관찰한 바로는 VDU상에 제공하고자 하는 정보가 text 형태일 경우에는 좌측에서 우측으로, 위에서 아래로 시선이 이동하는 패턴을 보였으며, graphic 형태의 정보일 경우에는 이와는 조금 달리 중앙에서 좌우, 아래위로 이동하는 경향을 관찰할 수 있었다. 따라서 전달하고자 하는 정보의 형태에 따라서 배치의 기준을 달리해야함을 확인할 수 있었다.
글루타르알데하이드 고정 소심 낭막에서의 내피세포 증식에 대한 글루탕산 및 파라벤용액의 효과
김범식,이문환,유세영,김원곤,Kim, Beom-Sik,Lee, Mun-Hwan,Yu, Se-Yeong,Kim, Won-Gon 대한흉부심장혈관외과학회 1996 Journal of Chest Surgery (J Chest Surg) Vol.29 No.1
The conventional glutaraldehyde (GA) fixation method of tissue valves is considered to be responsible for accelerated valve degeneration. The release of toxic GA from the valve tissue is believed to limit endothelial cell (EC) ingrowth. Removal of toxic GA by reaction with L-glutamic acid and storage in a Paraben solution may offer good EC growth. To investigate the conditions for endothelialization of tissue valves, the growth properties of ECs on the conventionally and alternatively treated pericardial tissue were compared. Conventional preparation included zero-pressure fixation for 72 hours in phosphated-buffered saline (PBS) solution containing 0.5% GA at 4$^{\circ}C$ and storage into PBS containing 0.2% GA(group I). Alternatively treated pericardial tissues were divided into three postfixation treatment groups : (1) storage in PBS solution containing Paraben(group II), (2) treatment with PBS containing 8$^{\circ}C$ L-glutamic acid(PH 7.35) and storage in PBS solution containing Paraben (g oup III), (3) treatment with L-glutamic acid dissolved in distilled water (PH 3.5) (group IV). Pericardial tissue were transferred into the 24-well plate after storage for 4 weeks. ECs were harvested enzymatically from the bovine pulmonary artery and grown to confluence on culture flask surfaces. Detached ECs by trypsin were incubated into the each well of the 24-well plate including test pericardial tissues. Cells were detached by trypsin, 1, 2, 3, 5, 7 days after incubation and counted on the hemacytometer. Cell viability test was performed by frypan-blue exclusion method. Acute cell death in the group I were found even after prolonged washing. The group II showed prolonged cell survival compared with the group I. Both group III and group IV showed better cell growth than group II. There was no statistically significant difference between group III and group IV method in terms of EC growth. This results suggest that treatment by L-glutamic ac id and storage in a Paraben solution be a promising approach for improvement of durability of GA-treated tissue valves.
김범식 대한흉부심장혈관외과학회 1986 Journal of Chest Surgery (J Chest Surg) Vol.19 No.3
Syphilitic aortic aneurysm is a rare lesion today. We experienced a case of huge syphilitic ascending aortic aneurysm with aortic insufficiency. Surgical correction was done by replacement of ascending aorta with woven Dacron graft and aortic valve replacement under cardiopulmonary bypass. There is no abnormality in postoperative aortography. The postoperative course was uneventful.
김범식 대한흉부심장혈관외과학회 1986 Journal of Chest Surgery (J Chest Surg) Vol.19 No.3
Primary intrathoracic liposarcomas are extremely rare tumors. 50 cases of mediastinal liposarcoma till 1977 have been recorded in the world literature, and 2 cases of pleural origin were reported in 1967. We report two cases, one is mediastinal origin and the other is pleural origin.