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흰쥐 유양동 폐쇄술에 사용한 Hydroxyapatite Cement와 Demineralized Bone Matrix의 효과 및 조직병리학적 비교 연구
구태우,장윤석,김소향,김수진,홍숙희,강명구 대한이비인후과학회 2008 대한이비인후과학회지 두경부외과학 Vol.51 No.9
Mastoid obliteration surgery is a useful technique for otitis media either with or without cholesteatoma. Obliterating materials have to satisfy low antigenecity, less inflammation, little tissue resorption, high regeneration power and good integration into the host tissue. The aim of our study is to evaluate histopathological changes and effectiveness resulting from the different obliterating materials in the temporal dorsal bullae in rats. Materials and Method:We divided the rats into two groups. Group A was untreated, but group B underwent removal of mastoid mucosa with 2% trichloroacetic acid (TCA). Both groups had mastoid obliteration by the implantation of hydroxyapatite cement (Mimix®) and demineralized bone matrix (Regenafil®). Twelve weeks after the implantation, a histological study was performed to evaluate remaining implanted material, new bone formation and the formation of cysts within the bullae. Results:There was no or minimal inflammation or foreign body reactions in the mastoid obliteration groups with Mimix® and Regenafil®. In the obliterated group that was not treated with 2% TCA, the remaining implanted material with Mimix® group was more than in the Regenafil® group (p<0.05). The obliterated groups of Mimix® and Regenafil® were similar with respect to new bone formation. The mucocele formation in the obliterated groups treated with 2% TCA was less than in the obliterated groups not treated with 2% TCA (p<0.05). Conclusion:We suggest that Mimix® and Regenafil® could be valuable resources as graft materials for mastoid obliteration procedures. The research continues for evaluation of long term results of these materials and their potential as graft materials. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:777-82)
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구태우,박찬수,김양도,이두용,박성균,이재호,최성묵,Chul Young Choi 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.67 No.9
A polymer electrolyte membrane water electrolysis system can produce high-purity hydrogen gases in a highly efficient manner. However, the level of hydrogen gas production is still small. In addition, noble-metal catalysts for the reaction in acidic environments, as well as an additional drying step to remove water contained in the hydrogen, are required. Therefore, water electrolysis system with high efficiency and lower cost, an alkaline anion-exchange membrane system that can produce high-purity hydrogen without a noble-metal catalyst, is needed. Nano-size NiCo2O4 powders were prepared by using a sol-gel method to achieve an efficient and economical water electrolysis system. When the powder was calcined at 450 C, the crystallinity and the cyclic voltammogram measurement showed the best values. In addition, the 15-wt.% polytetrafluoroethylene mixed NiCo2O4 powders exhibited the largest cyclic voltammetry active area and the highest oxygen evolution reaction activity with the appropriate stability.
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