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강원택,한규희,조광호,박성광,강성귀 의과학연구소 1990 全北醫大論文集 Vol.14 No.1
Total of 25 systemic lupus erythematosus (SLE) was analyzed from January 1979 to august 1989 in Chonbuk National Hospital. Two cases were male and 23 cases were female making the male to female ratio of about 1:12. Subject's ages were 14 to 49, with highest group in their 20's and 30's. mucocutaneous manifestation of SLE was the most common disorder(80%), followed by systemic(75%), musculoskeletal(72%), hematologic(72%) and renal (56%) findings, respectively. The most common renal manifestation was proteinuria( 36%). Renal failure was developed in 16%. The most common histological finding by renal biopsy was diffuse proliferative glomerulonephritis(75%). Antinuclear antibody(ANA) positive revealed 81.85, anti-deoxyribonucleic acid antibody(anti-DAN Ab) 75%, hypocomplementemia 90.5%, and lupus erythematosus(LE) CELL 47.6%, respectively. The remission rate of steroid or cyclophosphamide was 64%. The causes of death were systemic infection, renal failure and cardiopulmonary disturbance. The motality rate was 8%.