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      • 호텔 컨벤션센터 활성화를 위한 마케터의 역할과 전략적 제휴에 관한 연구

        하종명 한국문화관광학회 2000 문화관광연구 Vol.2 No.1

        This paper arranged the theory of active marketing technology to introduce continued convention by activating hotel convention center, pursuing the rationalization of hotel management, and offering the convenience of convention participants. First, the role of hotel convention marketers is to do the marketing activities through the analysis of the elements effecting on buying behaviors. It is very effective to analyze the element effecting on buying behaviors such as personnel characteristics, cultural features, social levels and way of life and to apply it to the marketing. Second, it is very effective for the hotel convention marketers to have partnership to increase marketing activities of the convention centers. The partnership is to associate, share and participate together. To increase the satisfaction level of utilize various programs to introduce conventions. They need to offer participants the convenience before and after the convention by concluding the partnership with travel agency, shopping center, transportation companies, recreation facilities, tourist restaurant, and so on.

      • 안정 동위체 표지 다차원 NMR 법에 의한 c-Ha-Ras 단백질의 구조해석

        하종명 신라대학교 자연과학연구소 2004 自然科學論文集 Vol.13 No.-

        In order to elucidate the structural change between the GDP-bound and GTP-bound forms of the Ras protein, isotope-aided 2D) and 3D NMR experiments were performed for uniformly ^(15)N-^(13)C labeled sample. First, most of the backbone resonances (N, NH, C_(α), CO) were assigned for the GDP-bound form by HNCO, HNCA and HCACO experiments. Next, HCCH-TOCSY and CT-HCCH-COSY experiments were performed for observation of side chain resonances of the Ras protein. For the GTP-bound form, the resonances due to G10-G13, I21, Y32-S39, and D57-Y64 were not identified clearly due to line broadening. Strength of the magnetic field strongly influenced the line shape of the resonances of residues near these regions of the GTP-bound form in ^(1)H-^(15)N HSQC spectrum, otherwise such an effect was not observed for the GDP-bound form. These results suggested that chemical exchange between multiple conformations occurred in the GTP-bound form.

      • 관광호텔 勞使關係의 安定化 방안에 관한 연구

        하종명,이우상 진주여자전문대학 1997 論文集 Vol.20 No.-

        The purposes of this study are to find out various significant factors impinging on the stability of labor-relations and their potential effects, and to propose effective approaches for enhancing the stability of labor-relations in tourist hotels. Specifically, the management system of tourist hotels and the empliyees' characteristics were selected as independent variables, and the stability of labor-relations was employed as subordinate variables. For these purposes, hypothesis was established as follows: Relation between independent variables(employees' characteristics) and the subor-dinate variable of the stability of labor-relations(labor harmony) should show significant difference. The samples of this study were 57 hotels in Seoul, Pusan, Taigu, TaiJun, Kyeongju, and Kyeongnam province. Enhancement of employees' Job attitude: the higher efficacy and pride the employees have toward their hotels, the higher degree of committment they may show to their Jobs, thus leading to lower rate of turnover and higher level of Job satisfaction among employees. Optimal labor-harmony may be secured when the employees are willing to sacrifice for the growth of their hotels. As a prerequisite for this harmony, new knowledge, skill, information which are required for employees' job performances must be provided to guarantee efficient communication.

      • 호텔 從事員 敎育에 關한 硏究

        河宗明 진주여자전문대학 1991 論文集 Vol.14 No.-

        The hotel business has become a part of the third industry influencing the development of the tourism industry. As the toursim growing as one of the important industries, the employees of tourism generally being given service education, but it is generally pointed out that such education is still far from adequate. The goal of this treatise is to provide materials for the devices on the development of our national toursim hotel and The researcher some suggestions to improve the guality of employees in the future. The suggestions are as follows : 1) on the educational system : it is urgent to establish the national professional school of tourism hotel and to cultivate professors and specialists. 2) We should try harder to operate the educational-industrial complex more effectively. 3) A more effective enlightment is needed to improve the nation-wide recognition for the field of the tourism hotel.

      • 호텔의 고객지향성과 서비스이미지에 관한 연구

        하종명 한국관광식음료학회 1999 관광식음료경영연구 Vol.10 No.1

        Customer-Orientation can be referred to as the concept of creating and maintaining a superior value within the market by responding to the 'wants of the customer' in regards to the Hotel. In other words, customer-orienated hotel is forcasting a customer' response to being different from other competitors, competing with others, and winning in the market. Therefore, hotels exert their efforts in various customer-oriented activities which may result in customer satisfaction. The pruposes of this study are to find out various significant factors impinging on customer-orientation and service image in hotels. For these purposes, two hypothesis were established, and the samples of this study were 15 hotels in Pusan, KyeongJu. The verification of the proposed hypothesis showed the following results: First, service quality and customer-orientation were found to be significantly related. In detail, the employees of hotel were shown to be affected in sales management, human relationship and service quality. Second, customer-orientation and service image were found to be significantly related. namely, the customer-orientation of hotel' employee were found to be significantly related with hotel service image. The research results and suggestions of this study are as follows: First, it is necessary that provide better service/product to satisfy the customers. Second, it is necessary that the employees of tourist hotel try to resolve the complaint of customers. Third, it is necessary that the employees of hotel try to improve the image as good service.

      • KCI등재후보

        In vitro 검출시스템을 이용한 해양생물 추출물로부터 에스트로겐 활성 검증

        하종명,이상현 한국생명과학회 2003 생명과학회지 Vol.13 No.6

        천연물에 포함되어 있는 에스트로겐 효과를 가지는 성분의 생체 내에서의 직접적인 효과를 검정하기 위하여, 에스트로겐 수용체를 발현하는 것으로 알려진 인체 유방암 세포주 MCF7에 에스트로겐에 반응성을 나타내도록 고안된 CAT 리포터 플라스미드를 도입한 in vitro 검출시스템을 사용하여 에스트로겐 활성을 측정하였다. 이미 여러 분야에서 그 기능성의 연구가 활발히 진행되고 있는 광합성 조류인 스피루리나(spirulina)와 파래 등의 해양식물을 대상으로 에스트로겐 반응 리포터 시스템을 이용하여 에스트로겐 활성을 측정하였다. 그 결과, 스피루리나 에탄올 추출물의 CAT 활성은 $500\mug/ml\; 와\; 50 \mug/ml$의 농도에서 표준물질인 $17\beta-estradiol$의 농도 $10^{-8}$ M과 비슷한 정도의 에스트로겐 활성 효과를 나타내었고, $5\mug/ml$의 농도에서는 표준물질인 $17\beta-estradiol$의 농도 $10^{-10}$ M과 비슷한 정도의 에스트로겐 활성 효과를 나타내었다. 하지만 파래 추출물의 경우에는 에탄올을 처리한 대조군과 비교하여 유의한 CAT활성 변화를 나타내지 않았다 한편, 불가사리와 새우 등의 해양동물을 대상으로 한 실험에서는 에탄올을 처리한 대조군과 비교하여 유의한 CAT 활성 변화를 나타내지 않았다. 이 연구 결과로 광합성 조류인 스피루리나에 에스트로겐 활성을 효과적으로 나타내는 생리활성성분이 포함되어 있을 수 있다는 가능성을 확인하였다. In order to verify the occurrence of an estrogenic compound in natural products, the estrogenic activity was measured using an in vitro detection system. For this system, human breast cancer cell line MCF7 was transfected using an estrogen responsive CAT reporter plasmid. Estrogenic activities of photosynthetic algae spirulina and sea lettuce were evaluated using this system. Estrogenic activities of a $500\mug/ml\; and\; 50 \mug/ml$ ethanol extracts of spirulina were as much as that of $10^{-8}$M standard solution (17$\beta$-estradiol) and activity of $5\mug/ml$ ethanol extract of spirulina was as much as that of $10^{-10}$ M standard solution. However, no significant estrogenic activity was observed using sea lettuce extract. Estrogenic activities of marine animals, such as star fish and shrimp, were also evaluated using this system, however, no significant estrogenic activity was observed in these extracts. In this result, it is confirmed that spirulina extract possesses estrogenic compound.

      • 人間의 c-Ha-ras 發癌性 蛋白質에 結合되어 있는 GDP의 形態

        河鍾明 新羅大學校 1990 論文集 Vol.29 No.-

        ¹H-NMR spectra were analyzed of a GDP/GTP-binding domain of human c-Ha-ras gene product(residues 1-171) in which glutarmine-61 was replaced by leucine [ras(L61/1-171) protein]. By one-dimensional and two-dimensional homonuclear Hartmann-Hah spectroscopy and nuclear Overhauser effect (NOE) spectroscopy of the complex of the ras(L61/1-171) protein and GDP, the ribose H1', H2', H3' and H4' proton resonances of the bound GDP were identified. The guanine H8 proton resonance of the bound GDP was identified by substitution [8-²H]GDP for GDP. The dependences of the H1' and H8 proton resonance intensities in the duration of irradiation of the H1', H2', H3' and H8 protons were measured. By numerical simulation of these time-dependent NOE profiles, the conformation of the protein-bound GDP was elucidated ; the guanosine moiety takes the anti form about the N-glycosidic bond with the dihedral angle of χ=-124±2。 and the ribes ring takes the C2'-endo form. Such an analysis of the conformation of a guanine nucleotide as bound to a GTP-binding protein will be useful for further studies on the molecular mechanism of the conformational activation of ras proteins on ligand substitution of GDP with GTP.

      • 커미트먼트의 유형이 조직에 미치는 영향에 관한 연구

        하종명 진주여자전문대학 1995 論文集 Vol.18 No.-

        It appears that low levels of commitment are largely dysfunctional for both the individual and the organization : individual career advancement may be severely hampered, while the organization may suffer from an unstable, disloyal work force. The advantages of moderate levels of commitment generally outweigh the disadvantages. The work force is more stable and satisfied without being consumed by the organization. Individuals are able to adjust to behavioral settings by varying their degrees of commitment according to the perceived attractiveness and the requirements of the settings. At high levels of commitment, it appears that the costs of commitment outweigh the advantages. Individuals may advance more rapildly in their careers, and the organization's production demands may be met with greater ease. In brief, the commonly assumed linear relationship between commitment and desirable consequences should be questioned. An inverted U-shaped curve between thse variables with an apes at a moderate level of commitment may be a more accurate description of the relationship. Individual and organizational needs appear to be in balance with moderate levels of commitment.

      • SCIESCOPUSKCI등재

        인간의 c - Ha - ras 발암성 단백질에 결합되어 있는 GDP 와 GTPγ의 형태 비교

        하종명,Gota Kawai,Tatsuo Miyazawa,Shigeyuki Yokoyama ( Jong Myung Ha ) 생화학분자생물학회 1993 BMB Reports Vol.26 No.1

        A normal ras protein and two of the mutant proteins were prepared to investigate the biochemical properties of ras proteins produced by ras genes. The methods for the preparation of ras proteins include 1) the truncation of c-Ha-ras protein at the position 18 from carboxy-terminal producing [ras(G12/1-171) protein], 2) the replacement of glycine by valine at position 12 of the ras protein from amino-terminal followed by the truncation of c-Ha-ras protein at the position 18 from carboxy-terminal [ras(V12/1-171) protein], 3) the replacement of glutamine by leucine at the position 61 followed by the truncation of c-Ha-ras protein at the position 18 from carboxy-terminal [ras(L61/1-171) protein]. The proton resonances of H8(guanine) and H1`, H2`, H3`, H4`, H5` (ribose) of the GDP and the GTP_γS [Guanosine 5`-0-(3-thiotriphosphate)] bound to ras(1-171) proteins were identified. By numerical simulation of these irradiated time-dependent NOE profiles, the conformations of the protein-bound GDP and GTP S were elucidated. The guanosine moieties of GDPs bound to three ras(1-171) proteins take the anti form about the N-glycosidic bond with a dihedral angle of χ= -120° and the ribose ring take the C2`-endo forms that were independent with point mutation. In contrast to the conformation of the bound GDP, the guanosine moieties of GTP_γSs bound to ras(1-171) proteins had anti-C3`-endo form and a dihedral angle of χ=-80°, and were not affected by the point mutation of ras(1-171) protein. The role of the interaction between the bound guanine nucleotide and effector region is discussed with regard to the mechanism of the ras proteins.

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