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11-Methoxyviburtinal, A New Iridoid from Valeriana jatamansi
Ye-Gao Chen,Li-Li Yu,Rong Huang,Yu-Ping Lv,Shi-Hong Gui 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.10
Five compounds of iridoids, lignan and phenylpropanoid glycosides were isolated from the roots of Valeriana jatamansi by column chromatography. Their structures were elucidated as 11-methoxyviburtinal (1), baldrinal (2), prinsepiol-4-O-β-D-glucoside (3), coniferin (4), and hexacosanic acid (5) by spectroscopic analysis. 11- Methoxyviburtinal was a new compound, and others were isolated from the plant for the first time.
3’’-Hydroxyamentoflavone and Its 7-O-Methyl Ether, Two New Biflavonoids fromAristolochia contorta
Ye-Gao Chen,Li-Li Yu,Rong Huang,Jia-Chuan Liu,Yu-Ping Lv,Yong Zhao 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.11
Two new biflavonoids, 3’’-hydroxyamentoflavone-7-O-methyl ether (1) and 3’’-hydroxyamentoflavone (2), were isolated from the fruits of Aristolochia contorta Bge. Their structures were elucidated by HR-ESI-MS, 1D-, and 2D-NMR spectroscopy.
Chen Ye,Zhen Yu,Wan Jili,Yin Xia,Li Siqi,Liu Jiayin,Zhang Guodong,Mi Tiezhu 한국미생물학회 2022 The journal of microbiology Vol.60 No.8
The differences in methanogen abundance and community composition were investigated between nearshore and offshore sediments in the South Yellow Sea (SYS). Shannon, Simpson, and Chao1 indices revealed a higher diversity of methanogens in the nearshore sediments than in the offshore sediments. The Mann–Whitney U test demonstrated that the relative abundance of Methanococcoides was significantly higher in the offshore sediments, while the relative abundances of Methanogenium, Methanosarcina, Methanosaeta, Methanolinea, and Methanomassiliicoccus were significantly higher in the nearshore sediments (P < 0.05). The abundance of the mcrA gene in the nearshore sediments was significantly higher than that in the offshore sediments. Furthermore, a similar vertical distribution of the methanogen and sulfatereducing bacteria (SRB) abundances was observed in the SYS sediments, implying there is potential cooperation between these two functional microbes in this environment. Finally, total organic carbon (TOC) was significantly correlated with methanogen community composition.
Long noncoding RNA atlas of the inflammation caused by asthma in mice
Ye Chen,Shou‑di He,Xiao‑dong Li,Zhi‑li Hu,Chao Zhang,Feng Xu 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.4
There is little evidence regarding the roles oflong noncoding RNAs (lncRNAs) in inflammation caused byasthma. In this study, we successfully generated an asthmamouse model that was induced by ovalbumin (OVA). Theeffects of dexamethasone (Dex) treatment on lung tissuewere investigated using pathological and biochemicalmethods, including Diff-Quik staining, enzyme-linkedimmunosorbent assay (ELISA), hematoxylin–eosin (H&E)staining, and western blotting (WB). The inflammation waseffectively relieved with Dex treatment. High-throughputsequencing revealed that a total of 1490 lncRNAs were detected in lung tissue samples. Differential expressionanalysis revealed that the Dex group had 20 upregulatedand 15 downregulated lncRNAs compared with those inthe Model group. Moreover, nine differentially expressedand inflammation-related lncRNAs were verified by quantitativereal-time reverse transcription polymerase chainreaction (qRT-PCR). Furthermore, the regulation networksof these nine lncRNAs, their potential binding microRNA(miRNAs), and the putative target genes showed that theselncRNAs play important roles in the nuclear factor kappalight-chain-enhancer of activated B cells (NF-κB) signalingpathway. We further identified the expression levels of threepotential binding miRNAs by qRT-PCR. The results of thisstudy contribute to a better understanding of the functionsof lncRNAs in inflammation caused by asthma.
Juvenile hormone regulation on the flight capability of Bactrocera dorsalis (Diptera: Tephritidae)
Chen Peng,Chen Min,Ye Hui,Yuan Ruiling,Du Chunhua,Ong Su Ping 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4
The oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae), is considered a major economic threat in many regions worldwide. In order to better understand the flight capacity of B. dorsalis and its physiological basis, the functions and regulatory roles of juvenile hormone (JH) in the flight muscle of B. dorsalis were studied under a controlled environment. JH titer of B. dorsalis varied with age and sex. Females have higher JH titers and better flight capabilities than males, given that the increase in JH also corresponded to the ovarian development and maturation in females. The flight duration and distance of both males and females increased with the gradual increase of JH titer after adult emergences. Both JH titer and flight capability peaked in 15-d-old adult and declined subsequently with age. Flight activity stimulated the production of JH as adults flown for 24 h on the flight mills have the highest JH titers compare to adults flown on shorter flight durations. Adults treated with 0.5 µg and 5 µg of JH III were able to fly long durations and long distances, nevertheless when JH titer was too low or too high, it would restrict the flight ability of the fly. The mutual reinforcement of JH and flight activity provides fundamental understanding on the physiological aspects of the flight capability and dispersal, which facilitates strategies for the long-term control of this destructive pest.