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See-Hoon Jeong,Ju-Il Jin,Hwa-Pyeong Park,Jee-Hoon Jung 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.6
Nowadays all-metal induction heating (IH) cooktops have become popular for heating various pots quickly and safely. A load adaptive modulation (LAM) method was proposed to improve the IH power delivery capability and the cost-eff ectiveness of an all-metal IH system. However, this method shows poor power conversion effi ciency under light-load conditions since a high switching loss is induced using the pulse frequency modulation (PFM) method in the series resonant inverters for IH applications. In this paper, a multi-mode control strategy for an IH system employing the LAM method is proposed to improve light-load effi ciency when compared with the conventional LAM method. The proposed multi-mode control algorithm automatically changes its modulation according to the pots’ material-dependent resistance. The modulation method is selected to improve the light-load effi ciency using the proposed control strategy. Experimental results demonstrate the validity and performance of the proposed multi-mode control algorithm with a 2-kW prototype IH series resonant inverter and various-material pots.
최세민(See Min Choi),최재휘(Jae Hwi Choi),화정석(Jeong Seok Hwa) 대한비뇨기종양학회 2020 대한비뇨기종양학회지 Vol.18 No.1
During last many decades, androgen deprivation therapy (ADT) was the main treatment of choice for metastatic castration-naïve prostate cancer (mCNPC). However, there are now more possible treatment options for mCNPC. In CHAARTED, GETUG-AFU 15, and STAMPEDE trial, docetaxel added to ADT improved overall survival compared to ADT alone in mCNPC. Also, STAMPEDE and LATITUDE trial revealed that abiraterone added to ADT improved overall survival compared to ADT alone for mCNPC patient. Furthermore, ARCHES and ENZAMET trial showed that enzalutamide added to ADT also can be a treatment option for mCNPC. Apalutamide added to ADT also improved survival compared to ADT alone in castration resistant prostate cancer patient. The usefulness of radiation therapy to primary tumor in mCNPC has also been studied in HORRAD and STAMPEDE trial. There are many ongoing trials for mCNPC setting. The aim of this paper is to review the current status of mCNPC management options.
박시형,이신원,정귀화,최창훈,이순희,한정훈,김정국,하승우,김보완 대한내분비학회 2001 Endocrinology and metabolism Vol.16 No.4
Autoimmune insulin syndrome is characterized by insulin autoantibody, hyperinsulinemia, and fasting hypoglycemia without previous insulin immunization. This syndrome shows discordant levels between immunoreactive insulin and C-peptide. Negative results of an anatomic study of the pancreas and an inability to reproduce hypoglycemia during a prolonged fast may be helpful in excluding insulinoma. Symptomatic hypoglycemia usually develops during an oral glucose tolerance test. This syndrome is a self-limited disorder. Recently, we experienced one case that developed symptomatic hypoglycemia during both the fasting & oral glucose tolerance test, and another that developed symptomatic hypoglycemia during the oral glucose tolerance test but not the fasting test. Hereby, we present these cases with a review of the literature
비결핵성 기관지탄분섬유증의 임상적 특징과 방사선학적 특징
장시진 ( See Jin Jang ),이숙영 ( Sook Young Lee ),김석찬 ( Suk Chan Kim ),이소영 ( So Young Lee ),조현선 ( Hyun Sun Cho ),박기훈 ( Ki Hoon Park ),문화식 ( Hwa Sik Moon ),송정섭 ( Jeong Sup Song ),박성학 ( Sung Hak Park ),김영균 ( 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.2
연구배경: 기관지내시경 시행 시 기관지점막에 탄분침착을 보이는 경우가 종종 있다. 이러한 기관지탄분섬유증은 결핵과 연관이 있다고 여겨지는데 최근 논문들에 의하면 결핵 이외의 만성폐쇄성 폐질환이나 폐렴 등의 다양한 폐질환과 관련이 있음이 보고되어 진다. 방법: 2003년 1월부터 2006년 7월까지 강남성모병원에서 기관지내시경 검사를 시행 받은 환자들 중 기관지 탄분침착이 있는 환자들을 대상으로 진료기록지를 통해 후향적 분석을 하였다. 기저질환, 임상소견, 폐기능 검사 및 조직소견, 방사선소견을 분석하였고 비결핵성 기관지탄분섬유증 환자에서 기관지협착이 동반된 경우 스테로이드 투여 시 그 치료성적을 분석하였다. 결과: 총 74명 중 비결핵성 기관지탄분섬유증 환자가 54명(73%)이었다. 이 중 41명(76%)에서 협착이 동반되었고 13명(24%)은 탄분침착만 보였다. 비결핵성 기관지탄분섬유증 환자 중 협착이 동반된 경우 14명에서 고식적 치료로 스테로이드를 투여하였는데 이 중 9명(64%)에서 임상적인 호전을, 6명(43%)에서 방사선학적인 호전을 보였다. 결론: 기관지 탄분섬유증은 결핵뿐만 아니라 만성폐쇄성 폐질환, 폐렴등의 다양한 호흡기 질환과 관련이 있다. 비결핵성 기관지 탄분섬유증 환자에서 고식적인 치료에 잘 반응하지 않을 경우 스테로이드를 고려해 볼 수 있다. Background: Bronchial anthracofibrosis, which is defined as bronchial narrowing with black pigmentation of the overlying bronchial mucosa, is frequently associated with tuberculosis. The aim of this study was to examine the relationship between bronchial anthrocofibrosis and to identify the clinical and radiological characteristics of non-tuberculous bronchial anthracofibrosis. Methods: All patients who showed bronchial anthracofibrosis in more than one segment on a bronchoscopic examination from January 2003 to July 2006 at Kangnam St. Mary`s hospital were enrolled in this study. The underlying diseases, baseline clinical characteristics, characteristic findings on a computed tomogram (CT) of the chest, pathologic findings of the bronchial mucosa, and the clinical response to steroid therapy were analyzed retrospectively. Results: A total 54 patients (19 males, 35 females) were enrolled with a mean age of 75 years. The most common presenting symptoms were cough, sputum and dyspnea. The predominant X-ray findings were peribronchial soft tissue attenuation with or without calcification, mediastinal lymphadenopathy with or without calcification and atelectasis. Fourteen non-tuberculous anthracofibrosis patients were treated with steroid. Nine patients were improved clinically, and 6 patients were improved radiologically. Conclusion: Bronchial anthracofibrosis is frequently associated with various pulmonary diseases not only tuberculosis but also COPD pneumonia etc. (Tuberc Respir Dis 2007; 63: 139-144)
( Ki Ho Kim ),( See-hwa Jeong ),( Takashi Hirano ),( Soo Nam Park ) 대한화장품학회 1999 대한화장품학회지 Vol.25 No.1
3 Kinds of PEG-hEGF conjugate, PEGl-hEGF, PEG5-hEGF, PEGlO-hEGF, were synthesized. Major fractions containing 2 chains of PEG were separated by preparative GPC. Molecular weight was estimated by GPC-MALLS, TOF-Mass and SDS-PAGE, and the data were well corresponding to calculated one. The cell proliferation effect of the conjugates was evaluated, indicating that the conjugate bound to longer chain PEG exhibits lower activity. Selective modification of hEGF and activity preservation of PEG- hEGF conjugate are undergoing.
The Effects of Alpinia katsumadai Extract on Anti-inflammation and Melanogenesis
( Jae Soeb Lee ),( See-hwa Jeong ),( Kang-ii Ko ),( Ki Ho Kim ),( Chom-kyu Chong ),( Soo Nam Park ) 대한화장품학회 1999 대한화장품학회지 Vol.25 No.1
Several solvent extracts from Alpinia katsumadai were prepared and their various anti-inflammatory activities were evaluated. Alpinia katsumadai extract showed high various anti-inflammatory effects among the 8 medicinal plant extracts. Butanol extract from Alpinia katsumadai showed a potent anti-oxidative and free radical scavenging activities. Free radical scavenging effect of butanol fraction of Alpinia katsumadai(lC<sub>50</sub> : 5μg/㎖) was higher than butylated hydroxytoluene(IC<sub>50</sub> : 50/μg/㎖) and ascorbic acid(IC<sub>50</sub> : 22μg/㎖). Alpinia katsumadai butanol fraction exhibited relatively high antioxidative activity(IC<sub>50</sub> : 80μg/㎖) compared to ascorbic acid. The inhibitory effect of Alpinia katsumadai ethanol extract on elastase exhibited 10 to 78% at 100 to 1000μg/㎖ concentration ; the IC<sub>50</sub> values with 465.7μg/㎖ for porcine pancreatic elastase(PPE) and 481.9μg/㎖ for human leukocyte elastase(HLE), respectively. The Alpinia katsumadai extract inhibited effectively hyaluronidase activity(IC<sub>50</sub> : 335μg/㎖), and showed inhibition in vitro on delayed hypersensitivity when it was topically applied. These results suggest that Alpinia katsumadai extract may reduce inflammatory skin trouble. The Alpinia katsumadai extract also showed higher inhibitory effect of melanin biosynthesis on cultured melanoma cell compared to arbutin and kojic acid.