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( Pan Jun Shin ),( Yeon Hui Kim ),( In Soo Lim ) 한국운동영양학회 2012 Journal of exercise nutrition & biochemistry Vol.16 No.1
The purpose of this study was to analyze the effects of intake of aronia, montmorency, and Prunus mume on 10 km endurance exercise by investigating changes in blood lactate, ammonia, creatine kinase (CK), and lactate dehydrogenase (LDH), and eventually to recommend them as ergogenic aids, which are effective for recovering from exercise fatigue and muscle damage. The subjects were divided into a P. mume intake group, an aronia intake group, a montmorency intake group, and a control group. Blood samples were taken from the brachial vein at rest, and at 0, 30 min, and 24 hr after running to measure recovery status. All data were analyzed by a two-way repeated-measures analysis of variance using SPSS. The results are summarized as follows: The changes in blood ammonia and LDH concentration following 10 km of running were not significantly different among the groups. However, lactate and CK recovery ratio increased significantly in the aronia and montmorency groups compared to those in the P. mume and control groups. In particular, CK concentration was significantly different in the montmorency group compared to that in the other groups. These results suggest that the effects of aronia and montmorency are associated with improved recovery from muscle fatigue and damage induced by highly intensive exercise, endurance exercise, or overtraining. In particular, montmorency is recommended as an ergogenic aid to inhibit muscle pain resulting from high-intensity endurance exercise.
Pan, Jeong Hoon,Kim, Jun Ho,Kim, Hyung Min,Lee, Eui Seop,Shin, Dong-Hoon,Kim, Seongpil,Shin, Minkyeong,Kim, Sang Ho,Lee, Jin Hyup,Kim, Young Jun Japan Society for Bioscience, Biotechnology, and A 2015 Bioscience, Biotechnology, and Biochemistry Vol.79 No.9
<P>Acetic acid has been shown to promote glycogen replenishment in skeletal muscle during exercise training. In this study, we investigated the effects of acetic acid on endurance capacity and muscle oxidative metabolism in the exercise training using in vivo mice model. In exercised mice, acetic acid induced a significant increase in endurance capacity accompanying a reduction in visceral adipose depots. Serum levels of non-esterified fatty acid and urea nitrogen were significantly lower in acetic acid-fed mice in the exercised mice. Importantly, in the mice, acetic acid significantly increased the muscle expression of key enzymes involved in fatty acid oxidation and glycolytic-to-oxidative fiber-type transformation. Taken together, these findings suggest that acetic acid improves endurance exercise capacity by promoting muscle oxidative properties, in part through the AMPK-mediated fatty acid oxidation and provide an important basis for the application of acetic acid as a major component of novel ergogenic aids.</P>
Shin, Pan-Seok,Cheung, Hee-Jun The Korean Institute of Electrical Engineers 2011 Journal of Electrical Engineering & Technology Vol.6 No.1
This paper proposes a method to calculate magnetostrictive forces, displacement, and vibration modes of a large-scale Brushless DC(BLDC) motor by using a magneto-mechanically strong coupling formulation. The force is calculated using the energy method with magnetostrictive stress tensor. The mechanical vibration modes are also analyzed by using the principle of Hamilton and the calculated magneto-elastic forces acting on the surfaces of the stator. To verify the algorithm, 3 MW BLDC motor is simulated, and the forces, displacements, and vibration modes are calculated. The result shows that the mechanically stressed core has more deformation or displacements than those of the normal condition.
Pan Seok Shin,Hee Jun Cheung 대한전기학회 2011 Journal of Electrical Engineering & Technology Vol.6 No.1
This paper proposes a method to calculate magnetostrictive forces, displacement, and vibration modes of a large-scale Brushless DC(BLDC) motor by using a magneto-mechanically strong coupling formulation. The force is calculated using the energy method with magnetostrictive stress tensor. The mechanical vibration modes are also analyzed by using the principle of Hamilton and the calculated magneto-elastic forces acting on the surfaces of the stator. To verify the algorithm, 3 MW BLDC motor is simulated, and the forces, displacements, and vibration modes are calculated. The result shows that the mechanically stressed core has more deformation or displacements than those of the normal condition.
Application of Polar Anisotropic NdFeB Ring-Type Permanent Magnet to Brushless DC Motor
Hyo Jun Kim,Dong Hwan Kim,Chang Seop Koh,Pan Seok Shin IEEE 2007 IEEE transactions on magnetics Vol.43 No.6
<P>A four-pole polar anisotropic sintered NdFeB permanent magnet (PM) with high surface magnetic flux density is developed using a dry pressing process with pulse magnetizing fields. The effects of powder-filling density, magnetic field intensity, distribution in the cavity, and premagnetization of the powder on the magnet performance are investigated. Through an application of the developed PM to a brushless DC motor, it is shown that the premagnetization of the powder is very effective for increasing the surface magnetic flux density. Experimental results with a brushless DC motor adopting the developed PM shows that the surface magnetic flux density is increased up to 0.63 T, and the back emf at 1000 rpm measured 2.7 V, which is 41% higher than the conventional segment type PM</P>
Fumarate-Mediated Persistence of <i>Escherichia coli</i> against Antibiotics
Kim, Jun-Seob,Cho, Da-Hyeong,Heo, Paul,Jung, Suk-Chae,Park, Myungseo,Oh, Eun-Joong,Sung, Jaeyun,Kim, Pan-Jun,Lee, Suk-Chan,Lee, Dae-Hee,Lee, Sarah,Lee, Choong Hwan,Shin, Dongwoo,Jin, Yong-Su,Kweon, Da American Society for Microbiology 2016 Antimicrobial agents and chemotherapy Vol.60 No.4
<P>Bacterial persisters are a small fraction of quiescent cells that survive in the presence of lethal concentrations of antibiotics. They can regrow to give rise to a new population that has the same vulnerability to the antibiotics as did the parental population. Although formation of bacterial persisters in the presence of various antibiotics has been documented, the molecular mechanisms by which these persisters tolerate the antibiotics are still controversial. We found that amplification of the fumarate reductase operon (FRD) in Escherichia coli led to a higher frequency of persister formation. The persister frequency of E. coli was increased when the cells contained elevated levels of intracellular fumarate. Genetic perturbations of the electron transport chain (ETC), a metabolite supplementation assay, and even the toxin-antitoxin-related hipA7 mutation indicated that surplus fumarate markedly elevated the E. coli persister frequency. An E. coli strain lacking succinate dehydrogenase (SDH), thereby showing a lower intracellular fumarate concentration, was killed similar to 1,000-fold more effectively than the wild-type strain in the stationary phase. It appears that SDH and FRD represent a paired system that gives rise to and maintains E. coli persisters by producing and utilizing fumarate, respectively.</P>
A New Anisotropic Bonded NdFeB Permanent Magnet and Its Application to a Small DC Motor
Kim, Hyo Jun,Koh, Chang Seop,Shin, Pan Seok IEEE 2010 IEEE transactions on magnetics Vol.46 No.6
<P> This paper reports the method of preparing <B><I>4-pole-oriented</I></B> <B><I>anisotropic bonded NdFeB magnet</I></B> and presents an application to a small size dc motor. The influence on the magnet performance in terms of alignment magnetic field intensity, powder filling density, and the temperature of compression mold tools are investigated. The design and optimization of the magnet and motor were done with the aid of electromagnetic field analysis based on the finite element method. Experimental results with a designed dc motor adopting the developed <B><I>anisotropic bonded NdFeB magnet</I></B> show 50% reduction of weight and volume. </P>