한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

카드뮴 처리한 인간 폐 섬유아 세포주에서 IL-6의 발현

신동훈 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.1

Cadmium is a highly toxic element responsible for acute and chronic toxicity in man and induces pathophysiological effects by modulating components of immune system. Cytokines are being increasingly recognized as essential mediators of normal and pathologic immune response. The present study has been investigated the effect of cadmium cytotoxicity for lung fibroblast and expression of cytokine gene in unstimulated and cadmium-treated lung fibroblast using reverse transcription-polymerase chain reaction. We showed that cadmium inhibited the cell proliferation and expression of IL-6, TGF-β mRNA in both unstimulated and cadmium-treated cell. The expression of IL-6 mRNA increased at 0.1mM cadmium treated for 24 hours than for 2 hours. This results suggest that cadmium stimulates expression of IL-6 mRNA in lung fibroblast.

FeTaNC 미세결정박막의 연자기 특성에 관한 연구

申東勳,崔雲,金亨駿,高兌赫 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.1

Magnetic properties and microstructures of FeTaNC thin films, which were deposited by magnetron reactive sputtering method, were investigated as a function of CH₄ and N₂ gas partial pressures. Magnetic properties of FeTaNC films were depended on total reactive gas pressures as well as CH₄/N₂ pressure ratios. For reactive gas partial pressures of 5 ∼ 10 %, optimum magnetic properties were observed in the FeTaNC films with proper CH₄/N₂ ratio. On the other hand, at 15% of gas partial pressure, FeTaN and FeTaC films showed superior properties to FeTaNC films. Above 15%, the magnetic properties of films rapidly degraded due to an excess incorporation of C and/or N atoms. Excellent soft magnetic properties of 17kG of Bs, 0.3 Oe of Hc, and 4000 of μ' (at 5 ㎒) were obtained in the FeTaNC films. The process windows of FeTaNC films which are showing good soft magnetic properties are larger than FeTa(N/C) films. High permeabilities of FeTaNC films could be explained by the Fe lattice distortion caused by N atoms, hence reduction of magnetic anisotopy. While precipitated TaN and TaC particles effectively supress the growth of α-Fe grains leading to a good soft magentic properties, FeN and FeC phases such as Fe3N, Fe4N, FexC have detrimental effects.

미생물 포괄고정화를 위한 고정화재의 비교검토

신동범,윤창훈,강경수 제주대학교 환경연구소 1997 환경연구논문집 : 제주대 Vol.5 No.-

We conducted the experiments to find out the appropriate gelling materials for the treatment of waste water by immobilizing microorganisms inside the gels. The gelling materials known to immobilize microorganisms or cells in them are polyacrylamide, polyvinylalcohol, sodium alginate, κ-carrageenan and chitosan. The gel strengths were determined by the breaking points of the pellet using a rheometer with reaction time. The polyacrylamide gels were retained their solidities and activities excellently compared with the other pellets of polyvinylalcohol, sodium alginate and chitosan with reaction time. It is considered that, in the other hand, the polyacrylamide gels are toxic to the single microorganisms and cells by free radicals during the formation of gels. We used activated sludge for the mmobilization, so it didn't matter the toxicity caused by free radicals. The profiles of waste water treatment by all the immobilized pellets using in this study were showed nearly similar patterns, but gel strength of all the gels except polyacrylamide pellets were getting weak and weak as reaction time goes by. It was concluded that the polyacrylamide gels are excellent for immobilization of activated sludge for waste water treatment, but in the case of immobilization of single microorganisms or cells, natural polysaccharides of sodium alginate, κ -carrageenan or chitosan are thought to be suitable, and it must be developed the techniques for elevating gel strength of nautral polysaccharides.

Adamkiewicz 동맥의 폐색에 의한 척수경색 1례

이광훈,이종걸,이태연,신동익,이성현,이상수,한설희,차상훈 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

지구자에 對한 文獻考察 및 最近 硏究 動向

신동훈,조명래 대한본초학회 2002 大韓本草學會誌 Vol.17 No.1

Objectives : So many kinds of disease are increasing tendency due to excessive alcohol ingestion, I reported some clues that the studies of origin, another name, property, related channels, effect, indication, contraindication for clinical use through oral administration and development of herb medicine acupuncture of Zhi Ju Zi, expecting the usage of relieving alcoholism that is like Pueraria root, Pueraria flower. Methods : 1. I investigated the 12 books of herbal medicine that Zhi Ju Zi was written in order of times. 2. I was looking for origin, another name, property, related channels, effect, indication, contraindication of Zhi Ju Zi which mentioned above 12 books of herbal medicine Conclusions : I reached conclusions as follows investigating of 12 herbal medicine books that origin, another name, property, related channels, effect, indication, contraindication of Zhi Ju Zi was written. 1. Zhi Ju Zi is fruit or seed attached peducle of pulpy substance of Hovenia dulcis THUNB. 2. Another names are Mi Qu Lu, Mu Mi, Mu Tang, Ji Ju Zi, Ji Zhao Zi. 3. Properties are sweet, even non-toxic and related to the channels of the heart, the spleen, the small intestine. 4. Pathogenic wind on head, lower abdomen rigidity, febrile disease, thirst, hiccup, vomiting, difficulty in urination, alcohol intoxication, fruit vegetable intoxication, paralysis, muscle numbness and unconsciousness are treated by the effect of relieving restlessness and thirst, clearing away upper heat, induce urination and defecation, relieving nausea, relieving roundworms intoxication 5. The person who has spleen-stomach biological energy deficiency with cold type is contraindicated, and over usage get roundworms.

대구지방 두부백선에 대한 임상 및 진균학적 관찰

신동훈,김경수,김기홍 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2

Background: The incidence and causative dermatophytes of tinea capitis has been changed with time. Objective: The purpose of this study was to investigate the clinical and mycological features of tinea capitis in Taegu. Methods: We evaluated the clinical and mycologic aspects of tinea capitis in 39 patients registered in Yeungnam University Hospital from January 1981 to June 1998. Results and Conclusion: The incidence of tinea capitis was 1.3% of 3,077 total dermatophytoses. The ratio of male to female patients was 1.6:1. Although most of the patients were children under the age of If, adult patients with tinea capitis were 23.1% of the cases. Frontal scalp was the most frequent site of tinea capitis. The most common causative organism of tinea capitis was Microsporum canis. Trichophyton rubrum and Trichophyton verrucosum were isolated, also.

카드뮴과 아연이 사람 단핵구성 세포주(THP-1)에서 IL-6의 분비에 미치는 영향

신동훈,서성일,서석권 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.3

Objectives : This study was performed to investigate effects of cadmium and zinc on IL-6 secretion using human monocyte in a culture system. Methods : We have used trypan blue dye exclusion methods to examine the effect of cytotoxicity of CdCl₂, ZnCl₂in THP-1 cells. IL-6 was measured by the ELISA method in the cell culture supernatants and the expression of IL-6 mRNA was examined by reverse transcription-polymerase chain reaction. Results : IL-6 production by THP-1 cells were decreased at 0.1 mM cadmium concentration (p<0.05) and increased as zinc concentration increased. Zinc prevented cadmium-induced suppression of IL-6, and the addition of a chelating agent, EDTA, restores IL-6 secretion. The expression of IL-6 mRNA decreased at 0.08 mM and 0.1 mM cadmium concentrations. Conclusion : This results suggest that cadmium depressed production and gene expression of IL-6 in stimulated human monocytes, and zinc prevented cadmium-induced suppression of IL-6.

고주파수대역에 적용되는 Fe-( BN, Si₃N₄)박막의 미세구조와 자기적특성에 관한 연구

申東勳,張勝彦,李宰源,南勝義 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

We have investigated the magnetic properties of FeBN thin films deposited by using RF magnetron sputtering and Fe-BN composite target. It was investigated that the area fraction of BN chips on the Fe target and partial pressure of nitrogen was the main factors influencing the soft magnetic properties and resistivity of FeBN thin film. The low addition of N₂increases significantly the soft magnetic properties and electrical resistivity. The good soft magnetic properties are obtained at N₂partial pressure of 5%, but futher increase in N₂ partial pressure degrade the soft magnetic properties due to formation of nitrides such as Fe₄N, Fe₂∼₃N. In a sputtering process, as the area fraction of BN increases, FeBN thin films fabricated at the area fraction of 0.25 exhibt soft magnetic properties (Bs∼17kG, Hc∼10e, μ∼1000).

광중합형 충전용 글라스 아이오노머 시멘트의 상아질 변연누출에 관한 정량분석

신동훈 大韓齒科保存學會 1995 Restorative Dentistry & Endodontics Vol.20 No.2