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        On sum-rate maximization in downlink UAV-aided RSMA systems

        Hua Duc-Thien,Do Quang Tuan,Dao Nhu-Ngoc,Cho Sungrae 한국통신학회 2024 ICT Express Vol.10 No.1

        The synergy of uncrewed aerial vehicles (UAVs) and the rate-splitting multiple access (RSMA) technique has thrived as a crucial enabler for multi-user broadband sixth-generation networks. This paper investigates a UAV-aided RSMA downlink communication system considering user mobility and the uniform rectangular array antenna design. In particular, the sum-rate maximization problem is formulated where the UAV beamforming matrix, common rate allocation, and UAV trajectory design are jointly optimized. The deep deterministic policy gradient (DDPG) approach has been proposed to address the nonconcave objective function. In addition, the safe action shaping technique is incorporated into the algorithm to satisfy the variable constraints of the problem statement. The numerical simulation results demonstrated that the proposed approach outperformed other benchmark schemes in various settings of transmit powers and fading environment levels.

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        Effective Elimination of Charge-associated Toxicity of Low Generation Polyamidoamine Dendrimer Eases Drug Delivery of Oxaliplatin

        Vo Minh Hoang Do,Long Giang Bach,Diem-Huong Nguyen Tran,Van Du Cao,Thi Nhu Quynh Nguyen,Duc Thuan Hoang,Van Cuong Ngo,Dai Hai Nguyen,Thai Thanh Hoang Thi 한국생물공학회 2020 Biotechnology and Bioprocess Engineering Vol.25 No.2

        Polyamidoamine (PAMAM) dendrimer is emerging as an effective nanocarrier for delivering anticancer drugs. Still, unmodified PAMAM dendrimer is hardly used in vivo because of unsatisfied drug release, high tendency of interfering with cellular membranes, and rapid clearance by reticuloendothelial system. In this study, low generation polyamidoamine (PAMAM) dendrimer G3.0 is developed and surface modified with methoxypolyethylene glycol (PAMAM G3.0-mPEG) to overcome its limitations. Specifically, PAMAM G3.0 conjugated with mPEG at different ratios are investigated to effectively eliminate its charge-associated toxicity, in which PAMAM G3.0-mPEG- 8 is chosen for oxaliplatin (OX) loading. Results reveal that OX-loaded PAMAM G3.0-mPEG-8 has desirable size, good entrapment efficiency, and sustained release with minimum drug leakage. In addition, Resazurin assay indicates that the toxicity of loaded OX is reduced as compared to free drug but still maintain substantially anticancer activity on HeLa cells, suggesting the potential application of PAMAM G3.0-mPEG-8 for OX delivery in cancer therapy.

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        Impact of long COVID-19 on posttraumatic stress disorder as modified by health literacy: an observational study in Vietnam

        Han Thi Vo,Tien Duc Dao,Tuyen Van Duong,Tan Thanh Nguyen,Binh Nhu Do,Tinh Xuan Do,Khue Minh Pham,Vinh Hai Vu,Linh Van Pham,Lien Thi Hong Nguyen,Lan Thi Huong Le,Hoang Cong Nguyen,Nga Hoang Dang,Trung 질병관리청 2024 Osong Public Health and Research Persptectives Vol.15 No.1

        Objectives: The incidence of posttraumatic stress disorder (PTSD) has increased, particularly among individuals who have recovered from coronavirus disease 2019 (COVID-19) infection. Health literacy is considered a “social vaccine” that helps people respond effectively to the pandemic. We aimed to investigate the association between long COVID-19 and PTSD, and to examine the modifying role of health literacy in this association.Methods: A cross-sectional study was conducted at 18 hospitals and health centers in Vietnam from December 2021 to October 2022. We recruited 4,463 individuals who had recovered from COVID-19 infection for at least 4 weeks. Participants provided information about their sociodemographics, clinical parameters, health-related behaviors, health literacy (using the 12-item short-form health literacy scale), long COVID-19 symptoms and PTSD (Impact Event Scale-Revised score of 33 or higher). Logistic regression models were used to examine associations and interactions.Results: Out of the study sample, 55.9% had long COVID-19 symptoms, and 49.6% had PTSD. Individuals with long COVID-19 symptoms had a higher likelihood of PTSD (odds ratio [OR], 1.68; 95% confidence interval [CI], 1.63–2.12; p<0.001). Higher health literacy was associated with a lower likelihood of PTSD (OR, 0.98; 95% CI, 0.97–0.99; p=0.001). Compared to those with long COVID-19 symptoms and the lowest health literacy score, those with long COVID-19 symptoms and a 1-point health literacy increment had a 3% lower likelihood of PTSD (OR, 0.97; 95% CI, 0.96–0.99; p=0.001).Conclusion: Health literacy was found to be a protective factor against PTSD and modified the negative impact of long COVID-19 symptoms on PTSD.

      • Introduction of construction condition in Vietnam

        ( Ha Minh ),( Le Nguyen Giap ),( Do Thi Ngoc Chau ),( Do Nhu Duc ) 대한지질공학회 2014 대한지질공학회 학술발표회논문집 Vol.2014 No.1

        This paper was conducted to evaluate the status of construction and infrastructure works in Vietnam. The approach included literature reviews to identify deterioration with site inspections and personal interviews to ascertain their validity. Results showed on overall picture of construction works in current condition, analyzed their main causes, and recommended the possible ways to improve the situation of construction works. Further, the paper provided information on policies and status of construction market in Vietnam so that Korean corporations would have a general view on Vietnamese construction industry at present

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