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      • Flexible marginalized models for bivariate longitudinal ordinal data

        Lee, Keunbaik,Daniels, Michael J.,Joo, Yongsung Oxford University Press 2013 Biostatistics Vol.14 No.3

        <P>Random effects models are commonly used to analyze longitudinal categorical data. Marginalized random effects models are a class of models that permit direct estimation of marginal mean parameters and characterize serial correlation for longitudinal categorical data via random effects (Heagerty, 1999). Marginally specified logistic-normal models for longitudinal binary data. <I>Biometrics</I> <B>55</B>, 688–698; Lee and Daniels, 2008. Marginalized models for longitudinal ordinal data with application to quality of life studies. <I>Statistics in Medicine</I> <B>27</B>, 4359–4380). In this paper, we propose a Kronecker product (KP) covariance structure to capture the correlation between processes at a given time <I>and</I> the correlation within a process over time (serial correlation) for bivariate longitudinal ordinal data. For the latter, we consider a more general class of models than standard (first-order) autoregressive correlation models, by re-parameterizing the correlation matrix using partial autocorrelations (Daniels and Pourahmadi, 2009). Modeling covariance matrices via partial autocorrelations. <I>Journal of Multivariate Analysis</I> <B>100</B>, 2352–2363). We assess the reasonableness of the KP structure with a score test. A maximum marginal likelihood estimation method is proposed utilizing a quasi-Newton algorithm with quasi-Monte Carlo integration of the random effects. We examine the effects of demographic factors on metabolic syndrome and C-reactive protein using the proposed models.</P>

      • In Situ Forming Gelatin Hydrogels-Directed Angiogenic Differentiation and Activity of Patient-Derived Human Mesenchymal Stem Cells

        Lee, Yunki,Balikov, Daniel A.,Lee, Jung Bok,Lee, Sue Hyun,Lee, Seung Hwan,Lee, Jong Hun,Park, Ki Dong,Sung, Hak-Joon MDPI 2017 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.18 No.8

        <P>Directing angiogenic differentiation of mesenchymal stem cells (MSCs) still remains challenging for successful tissue engineering. Without blood vessel formation, stem cell-based approaches are unable to fully regenerate damaged tissues due to limited support for cell viability and desired tissue/organ functionality. Herein, we report in situ cross-linkable gelatin−hydroxyphenyl propionic acid (GH) hydrogels that can induce pro-angiogenic profiles of MSCs via purely material-driven effects. This hydrogel directed endothelial differentiation of mouse and human patient-derived MSCs through integrin-mediated interactions at the cell-material interface, thereby promoting perfusable blood vessel formation in vitro and in vivo. The causative roles of specific integrin types (α<SUB>1</SUB> and α<SUB>v</SUB>β<SUB>3</SUB>) in directing endothelial differentiation were verified by blocking the integrin functions with chemical inhibitors. In addition, to verify the material-driven effect is not species-specific, we confirmed in vitro endothelial differentiation and in vivo blood vessel formation of patient-derived human MSCs by this hydrogel. These findings provide new insight into how purely material-driven effects can direct endothelial differentiation of MSCs, thereby promoting vascularization of scaffolds towards tissue engineering and regenerative medicine applications in humans.</P>

      • KCI등재

        Intermediate-term outcomes after robotic ureteral reconstruction for long-segment (≥4 centimeters) strictures in the proximal ureter: A multi-institutional experience

        Matthew Lee,Ziho Lee,Helaine Koster,Minsuk Jun,Aeen M. Asghar,Randall Lee,David Strauss,Neel Patel,Daniel Kim,Sreeya Komaravolu,Alice Drain,Michael J. Metro,Lee Zhao,Michael Stifelman,Daniel D. Eun 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.1

        Purpose: To report our intermediate-term, multi-institutional experience after robotic ureteral reconstruction for the management of long-segment proximal ureteral strictures. Materials and Methods: We retrospectively reviewed our Collaborative of Reconstructive Robotic Ureteral Surgery (CORRUS) database to identify all patients who underwent robotic ureteral reconstruction for long-segment (≥4 centimeters) proximal ureteral strictures between August 2012 and June 2019. The primary surgeon determined the specific technique to reconstruct the ureter at time of surgery based on the patient's clinical history and intraoperative findings. Our primary outcome was surgical success, which we defined as the absence of ureteral obstruction on radiographic imaging and absence of obstructive flank pain. Results: Of 20 total patients, 4 (20.0%) underwent robotic ureteroureterostomy (RUU) with downward nephropexy (DN), 2 (10.0%) underwent robotic ureterocalycostomy (RUC) with DN, and 14 (70.0%) underwent robotic ureteroplasty with buccal mucosa graft (RU-BMG). Median stricture length was 4 centimeters (interquartile range [IQR], 4–4; maximum, 5), 6 centimeters (IQR, 5–7; maximum, 8), and 5 centimeters (IQR, 4–5; maximum, 8) for patients undergoing RUU with DN, RUC with DN, and RU-BMG, respectively. At a median follow-up of 24 (IQR, 14–51) months, 17/20 (85.0%) cases were surgically successful. Two of four patients (50.0%) who underwent RUU with DN developed stricture recurrences within 3 months. Conclusions: Long-segment proximal ureteral strictures may be safely and effectively managed with RUC with DN and RU-BMG. Although RUU with DN can be utilized, this technique may be associated with a higher failure rate.

      • SCOPUSKCI등재

        Severe Adverse Events of Periocular Acupuncture: A Review of Cases

        Sang-Mok Lee(Sang-Mok Lee),Jun Wu(Jun Wu),Daniel Duck-Jin Hwang(Daniel Duck-Jin Hwang ) 대한안과학회 2023 Korean Journal of Ophthalmology Vol.37 No.3

        Acupuncture is recognized as a component of alternative medicine and is increasingly used worldwide. Many studies have shown the various effects of acupuncture around the eyes for ophthalmologic or nonophthalmologic conditions. For ophthalmologic conditions, the effect of acupuncture on dry eye syndrome, glaucoma, myopia, amblyopia, ophthalmoplegia, allergic rhinoconjunctivitis, blepharospasm, and blepharoptosis has been reported. Recently, several studies on dry eye syndrome have been reported and are in the spotlight. However, given the variety of study designs and reported outcomes of periocular acupuncture, research is still inconclusive, and further studies are required. In addition, although a systematic and reliable safety assessment is required, to the best of our knowledge, there have been no reports of a literature review of ocular complications resulting from periocular acupuncture. This review collected cases of ocular injury as severe adverse events from previously published case reports of periocular acupuncture. A total of 14 case reports (15 eyes of 14 patients) of adverse events published between 1982 and 2020 were identified. This review article provides a summary of the reported cases and suggestions for the prevention and management of better visual function prognosis.

      • Social Integration and Multiculture in Life-World

        Daniel B. Lee(이부덕) 대구가톨릭대학교 다문화연구소 2015 다문화와 인간 Vol.4 No.1

        세계화는 우리사회 여러 영역에 기회와 도전으로 임하고 있어 다문화적 기세의 적응과 조절, 그리고 변형을 요구한다. 사회복지는 사회 안정망의 실마리로 사회의 모든 성원이 질적인 삶을 영위할 수 있도록 유지하며 특히 의도적으로 사회적 기제의–그것이 정부이든 민간이든–가용자원을 동원, 보다 더 가난한자, 터전을 상실한 자와 주변인들의 역량강화에 주력할 뿐만 아니라, 최적수준의 사회통합과 평등 및 정의를 실현하도록 전문적인 잭임을 감당하는 것이다. 저자는 사회통합의 증진에 있어서 다문화적 힘의 중요성을 먼저 검토하고 공감문명시대에 문화 간 상호작용의 관점에서 세계화의 요구에 대응하는 사회복지의 책무를 논한다. 다음으로 생활세계 안에서 생활주기와 교차지역의 다면적 수준에서 다문화적 힘의 사회통합을 증진함에 있어서 사회복지가 실천하고 있는 것을 한국과 미국의 사례연구를 통해 사회통합의 차별적 단계의 보기를 들어 살펴보려한다. 마지막으로 교육, 조사, 정책 및 실천에 주는 다문화와 초문화의 작업에 주는 함의는 이전토의에 근거를 두었다. Globalization has brought with it both opportunities and challenges to every sectors of our society for transformative adaptation and accommodation of multicultural forces. Social welfare, as a key force of social safety-nets to ensure the sustainability of quality living for all members of a society, seeks intentionally to empower the poorer, the uprooted, and the marginal by mobilizing social mechanism, be it governmental or civic, as well as professional commitments to ensure equity and justice toward achieving an optimal level of social integration and social progress. The author first examine the significance of multicultural factors in advancing social integration and then addresses the role of social welfare profession in responding to the demands of globalization in terms of intercultural making for empathic civilization (Rifkin, 2009). Attempts are made here to demonstrate what social work actually does in life-world to advance social integration of multicultural forces at various levels of intervention over life=span and cross-borders. Case studies of Asian and American intermarriage are also made to illustrate differential stage aspects of social integration. In ending, several implications are drawn from the foregoing discussion for multicultual and transcultural works in education, research, policy and practice, for social welfare, and for interdisciplinary endeavors.

      • KCI등재

        Encountering God in Prayer and Action - A Theological Analysis of Simone Weil’s Spiritual Autobiography -

        Lee, Daniel Chungsoon 한국실천신학회 2016 신학과 실천 Vol.0 No.50

        Simone Weil (1909-1943), whose life is marked by hunger, suffering, and social praxis in a tumultuous time, is regarded as a great modern mystic in history of Christian spirituality. Although she did not want to belong to any institutionalize church, she was a mystic, experiencing God in an immediately way. She was striving for God, actively engaged in social, political issues in her time. In the mid-1930s Weil became increasingly drawn to Christianity but refused baptism into the Christian Church. However, she finally converted from Judaism to Christianity in 19131. As her faith dawned, Weil had strongly mystic experiences several times. She stayed outside of any church, but her passionate need to share the sufferings of others led her to fight with the anarchists in the Spanish Civil War and to work as a laborer. She ultimately died in England at the age of 34 by refusing to eat more than the rations Hitler allotted to her countrymen in occupied France. The extraordinary life of Simone Weil gave us a strong impression of a saint because she practiced the suffering way of Jesus Christ in her own life. Above of all, she shows us a way of encountering God in both her internal life and the suffering world, a spirituality balanced between personal prayer, contemplation, and social praxis. In addition, her spiritual journey teaches us the meaning of faith, prayer, mysticism, ritual, and church. Thus, it seems obvious that her spirituality can help us reflect ourself as Christians and formulate a spirituality of genuine prayer and action in the context of Korean churches. In this regard, it is timely significant to theologically analyze her spiritual autobiography to gain an understanding of spirituality from a new perspective in this changing world. In this article, I will explore her spirituality, focusing on her spiritual and theological writings collected in Waiting for God. In particular, I will fucus on her spiritual journey, centering on several turning points. I will first explicate the significance of her spiritual autobiography as a form of autobiography. Then, I will discuss her thought on theological themes such as God, Christ, mystical experience, truth, beauty, suffering, and Christianity. Last, I will critique some of her thought in order to develop a balanced spirituality between self and others, personal contemplation and social praxis in the context of the Korean church.

      • KCI등재

        Impacts of Soil Organic Matter on Microbial Community of Paddy Soils in Gyeongnam Province

        Daniel Son,Yeon-Kyu Sonn,Hang-Yeon Weon,Jae-Young Heo,Dae-Ho Kim,Yong-Jo Choi,Sang-Dae Lee,Yong Sik Ok,Young Han Lee 한국토양비료학회 2016 한국토양비료학회지 Vol.49 No.6

        Agricultural management of paddy soil depends on the effects of soil microbial activities. The present study evaluated the soil microbial community of 25 paddy soils in Gyeongnam Province by fatty acid methyl ester (FAME). The average of microbial communities in paddy soils were 32.2% of total bacteria, 16.7% of Gram-negative bacteria, 12.9% of Gram-positive bacteria, 2.0% of actinomycetes, 14.9% of fungi, and 1.3% of arbuscular mycorrhizal fungi. The communities of total bacteria (34.9%) and Gram-negative bacteria (19.4%) in soils with 30∼35 g kg<SUP>-1</SUP> of organic matter were significantly larger than those in soils with other organic matter levels. However, soils with 20∼30 g kg-1 of organic matter had significantly low ratio of cy17:0 to 16:1ω7c and cy19:0 to 18:1ω7c as compared with soils with 30∼35 g kg<SUP>-1</SUP> of organic matter, indicating microbial stress decreased (p < 0.05). In principal component analyses of soil microbial communities, Gram-negative bacteria should be considered as a potential responsible factor for the obvious microbial community differentiation that was observed between the two different organic matter levels in paddy fields. Thus, soils containing 20∼30 g kg<SUP>-1</SUP> of organic matter were responsible for strong effect on microbial biomass and stress in paddy fields.

      • KCI등재

        Christianity Encounters Confucianism : Spiritual Formation in a Comparative Perspective in Korea

        Lee, Daniel Chungsoon 한국실천신학회 2017 신학과 실천 Vol.0 No.55

        A religious pluralism is not a strange phenomenon in Korea because the Korean society consists of various living religions. Christianity is just one of those religions. Although Korean Christianity’s history, Catholic and Protestant, is not long, it has occupied a quarter of the whole population in south Korea. So, Christianity, a foreign Western religion, now exists as one of the main religions in Korea. Although Christianity is now a Korean people’s religion, it is also true that the Christianity introduced from Western countries is still not indigenized or inculturized into Korean culture in a true sense. That is, Christianity in Korea does not fully understand Korea’s pluralistic religious culture, so it still regards it as heretical. In this context, achieving a true encounter between Christian faith and Korean religious cultures is an important task for Christianity in Korea. It is extremely significant for Korean Christians to study comparatively other religions as living partners for Christian faith in order to make Christianity spiritually rich and fruitful in the Korean context. Although the main streams of Christianity are conservative and still opposed to other traditional religions, it is evident that Christianity in Korea has been influenced by other traditional religious cultures in whatever. In particular, the Confucian influence on Christianity in Korea was so strong because the state religion of the Choson dynasty, which lasted until the Japanese occupation in the modern times of Korea, was Confucianism. Even though many people don’t confess Confucianism as their religion, it is undeniable that Confucianism is functioning as a core and basis of Korean lives and cultures. The purpose of this paper is to explore spiritual formation for Korean Christians by doing a comparative study of Christianity and Confucianism in Korea. In this paper, I have dealt with the important issue, “Confucian-Christian dialogue” in the Korean context, focusing on the theme of spirituality. I first tried to define the term ‘spirituality’ from a comparative perspective. Second, with reference to the experience of interfaith encounters in Korea, I have searched for some models of Christian spirituality and spiritual formation which are desirable in the context of Korea. As conclusion, I have discussed about several tasks for the encounter between Christianity and Confucianism, especially for a spiritual formation in the context of the Korean Churches.

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