http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
The effects of grooves on wind characteristics of tall cylinder buildings
Yuan, Wei-bin,Yu, Nan-ting,Wang, Zhao Techno-Press 2018 Wind and Structures, An International Journal (WAS Vol.26 No.2
For most full-scale tall buildings the Reynolds number of a flow field around a circular cylinder under strong wind is usually greater than $2{\times}10^7$, which is difficult to achieve in most wind tunnel tests. To explore the wind characteristics of tall cylindrical buildings with equidirectional grooves from subcritical to transcritical flow ($6.6{\times}10^4{\leq}Re{\leq}3.3{\times}10^5$ and $9.9{\times}10^6{\leq}Re{\leq}7.2{\times}10^7$), wind tunnel tests and full-scale large eddy simulations were carried out. The results showed that the rectangular-grooves narrow the wake width due to the downstream movement of the separation point and the deeper grooves cause smaller mean and fluctuating pressure while the peak pressure is little affected. Furthermore, the grooves lead to lower frequency of vortex shedding but the Strouhal number remains at the range from 0.15 to 0.35. The drag coefficient of the cylinders with grooves was found to be 2~3 times as large as that of smooth cylinders.
Yuan, Shi-bin,Chen, Dai-wen,Zhang, Ke-ying,Yu, Bing Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.10
This study was undertaken to investigate the effects of oxidative stress on growth performance, nutrient digestibilities and activities of antioxidant enzymes of weanling pigs. In the experiment, 24 male $Landrance{\times}Yorkshire $weanling pigs were allotted to three groups of 8 animals each. Pigs were fed individually. According to a single factorial arrangement, pigs received diets with 5% of either fresh (group 1 and group 3) or oxidized fish oil (peroxide value was 786.50 meq $O_2/kg$ before inclusion in the diet, group 2). At the beginning of the experiment, pigs in group 3 received an intraperitoneal injection of diquat at 12 mg/kg of body weight. The trial lasted for 26 d. A metabolism test was carried out during the last 4 days of the second week. The results showed that feeding diets containing oxidized fish oil or injection with diquat depressed the growth performance and nutrient digestibilities of weanling pigs, decreased activities of antioxidant enzymes and increased concentration of malondialdehyde in plasma and liver. Intraperitoneal injection of diquat would induce more serious oxidative stress than oral intake of oxidized fish oil in the diet. In conclusion, administration of oxidized fish oil or diquat could induce oxidative stress in weanling pigs, and oxidative stress could depress growth performance and impact anti-oxidative ability of young pigs.
Yuan, Yiguo,Li, Bin Institute for Corpus Research 2021 Asia pacific journal of corpus research Vol.2 No.2
This paper makes a quantitative analysis of the diachronic evolution of ancient Chinese vocabulary by constructing and counting a large-scale rough annotated corpus. The texts from Si Ku Quan Shu (a collection of Chinese ancient books) are automatically segmented to obtain ancient Chinese vocabulary with time information, which is used to the statistics on word frequency, standardized type/token ratio and proportion of monosyllabic words and dissyllabic words. Through data analysis, this study has the following four findings. Firstly, the high-frequency words in ancient Chinese are stable to a certain extent. Secondly, there is no obvious dissyllabic trend in ancient Chinese vocabulary. Moreover, the Northern and Southern Dynasties (420-589 AD) and Yuan Dynasty (1271-1368 AD) are probably the two periods with the most abundant vocabulary in ancient Chinese. Finally, the unique words with high frequency in each dynasty are mainly official titles with real power. These findings break away from qualitative methods used in traditional researches on Chinese language history and instead uses quantitative methods to draw macroscopic conclusions from large-scale corpus.
Yuan, Jun-Bin,Yang, Luo-Yan,Tang, Zheng-Yan,Zu, Xiong-Bing,Qi, Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
Although enhancer of zeste homolog 2 (EZH2) has been reported as an independent prognostic factor in renal cell carcinoma (RCC), little is known about the exact mechanism of EZH2 in promoting the genesis of RCC. However, several studies have shown that dysregulation of the Wnt/${\beta}$-catenin signaling pathway plays a crucial role. Therefore, we determined whether EZH2 could affect ACHN human RCC cell proliferation and invasion via the Wnt/${\beta}$-catenin pathway. In the present study, we investigated the effects of short interfering RNA (siRNA)-mediated EZH2 gene silencing on Wnt/${\beta}$-catenin signaling in ACHN cells. EZH2-siRNA markedly inhibited the proliferation and invasion capabilities of ACHN, while also reducing the expression of EZH2, Wnt3a and ${\beta}$-catenin. In contrast, cellular expression of GSK-$3{\beta}$ (glycogen synthase kinase-$3{\beta}$), an inhibitor of the Wnt/${\beta}$-catenin pathway, was conspicuously higher after transfection of EZH2 siRNA. These preliminary findings suggest EZH2 may promote proliferation and invasion of ACHN cells via action on the Wnt/${\beta}$-catenin signaling pathway.
On the Surface Tension and Coulomb Energy of Neutron-star Ma
Yuan-Bin Wu 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.6
We briefly report the results from a study of the structure, the surface and the Coulomb energyof the core-crust transition layer of neutron stars with global charge neutrality. The results showthat the surface tension is a power-law function of the baryon number density in the core region. We also present analyses of the influence of the gravitational field on the transition layer andthe instability against Bohr-Wheeler surface deformations in the case of neutron stars obeyingglobal charge neutrality. If the core-crust transition is assumed to occur at the nuclear densitycore 2.7×1014 g cm−3, the instability sets the upper limit to the crust density, critcrust 1.2×1014g cm−3.
Molecular characterization of SMILE as a novel corepressor of nuclear receptors
Xie, Yuan-Bin,Nedumaran, Balachandar,Choi, Hueng-Sik Oxford University Press 2009 Nucleic acids research Vol.37 No.12
<P>SMILE (small heterodimer partner interacting leucine zipper protein) has been identified as a coregulator in ER signaling. In this study, we have examined the effects of SMILE on other NRs (nuclear receptors). SMILE inhibits GR, CAR and HNF4α-mediated transactivation. Knockdown of SMILE gene expression increases the transactivation of the NRs. SMILE interacts with GR, CAR and HNF4α <I>in vitro</I> and <I>in vivo</I>. SMILE and these NRs colocalize in the nucleus. SMILE binds to the ligand-binding domain or AF2 domain of the NRs. Competitions between SMILE and the coactivators GRIP1 or PGC-1α have been demonstrated <I>in vitro</I> and <I>in vivo</I>. Furthermore, an intrinsic repressive activity of SMILE is observed in Gal4-fusion system, and the intrinsic repressive domain is mapped to the C-terminus of SMILE, spanning residues 203–354. Moreover, SMILE interacts with specific HDACs (histone deacetylases) and SMILE-mediated repression is released by HDAC inhibitor trichostatin A, in a NR-specific manner. Finally, ChIP (chromatin immunoprecipitation) assays reveal that SMILE associates with the NRs on the target gene promoters. Adenoviral overexpression of SMILE represses GR-, CAR- and HNF4α-mediated target gene expression. Overall, these results suggest that SMILE functions as a novel corepressor of NRs via competition with coactivators and the recruitment of HDACs.</P>
Buckling Analysis of Steel H Column with Thermal Gradient Along the Flanges
Wei-bin Yuan,Pei-jun Ge,Yue-ting Shen,Shan-shan Cheng,Nan-ting Yu 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.2
This paper presents an analytical study about the axial compression buckling of H-section columns with one side of the flanges exposed to fire. The fire-induced thermal gradient along the flanges is obtained by using simplified Fourier heat conduction equation. The pre-buckling stress and bowing effect due to the non-uniform temperature distribution through the cross-section is considered. The analysis is accomplished by using the Rayleigh–Ritz method. The analytical solution is validated by finite element analysis using ANSYS. Finally, the parametric study is performed for different sections including different values of length, thickness ratio and width-to-height ratio.