First-principles investigation of V2CSe2 MXene as a potential anode material for non-lithium metal ion batteries

Wang Yanzong,Ma Yihan,Zhang Qinfang,Huang Rui,Gao Benling,Li Zhongwen,Li Guannan,Liang Feng 한국물리학회 2022 Current Applied Physics Vol.41 No.-

The electrochemical performances of the V2CSe2 MXene as anode materials for Na, K, Mg, Ca, and Al-ion batteries have been systematically investigated by the first-principles method. The adsorption energies of metal atoms show that Na, K, and Ca atoms can effectively adsorb on the V2CSe2, except for Mg and Al atoms. The large diffusion constants for Na, K, and Ca atoms calculated by the diffusion energy barriers (0.098 eV for Na, 0.066 eV for Ca, and 0.24 eV for Ca) indicate the high mobility on the V2CSe2 surface. Significantly, the maximum theoretical capacities of V2CSe2 reach up to 394.12 mA h/g for Na and Ca ions. Furthermore, the low average open-circuit voltage (OCV) (0.150 V for Na, 0.175 V for K, and 0.072 V for Ca) indicates the V2CSe2 is a suitable anode material. These results provide fundamental guidance for the V2CSe2 monolayer as anode materials of non-lithium metal-ion batteries.

Integrative applications of network pharmacology and molecular docking: An herbal formula ameliorates H9c2 cells injury through pyroptosis

Zhongwen Qi,Zhipeng Yan,Yueyao Wang,Nan Ji,Xiaoya Yang,Ao Zhang,Meng Li,Fengqin Xu,Junping Zhang The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

Background: QiShen YiQi pills (QSYQ) is a Traditional Chinese Medicine (TCM) formula, which has a significant effect on the treatment of patients with myocardial infarction (MI) in clinical practice. However, the molecular mechanism of QSYQ regulation pyroptosis after MI is still not fully known. Hence, this study was designed to reveal the mechanism of the active ingredient in QSYQ. Methods: Integrated approach of network pharmacology and molecular docking, were conducted to screen active components and corresponding common target genes of QSYQ in intervening pyroptosis after MI. Subsequently, STRING and Cytoscape were applied to construct a PPI network, and obtain candidate active compounds. Molecular docking was performed to verify the binding ability of candidate components to pyroptosis proteins and oxygen-glucose deprivation (OGD) induced cardiomyocytes injuries were applied to explore the protective effect and mechanism of the candidate drug. Results: Two drug-likeness compounds were preliminarily selected, and the binding capacity between Ginsenoside Rh2 (Rh2) and key target High Mobility Group Box 1 (HMGB1)was validated in the form of hydrogen bonding. 2 μM Rh2 prevented OGD-induced H9c2 death and reduced IL-18 and IL-1β levels, possibly by decreasing the activation of the NLRP3 inflammasome, inhibiting the expression of p12-caspase1, and attenuating the level of pyroptosis executive protein GSDMD-N. Conclusions: We propose that Rh2 of QSYQ can protect myocardial cells partially by ameliorating pyroptosis, which seems to have a new insight regarding the therapeutic potential for MI.

Correction: Adaptive Chaotic Gray Wolf Optimizer-Based Optimization of Decentralized AGC and Power Dispatching Controllers for Integrated Energy System with Heterogeneous Power Sources

Li Zhongwen,Bai Ningning,Cheng Zhiping,Wang Yi,Si Jikai 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.3

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Adaptive Chaotic Gray Wolf Optimizer-Based Optimization of Decentralized AGC and Power Dispatching Controllers for Integrated Energy System with Heterogeneous Power Sources

Li Zhongwen,Bai Ningning,Cheng Zhiping,Wang Yi,Si Jikai 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.2

With the increasing use of renewable energy sources connected to inverters in modern power systems, traditional units’ rotary inertia and frequency regulation capacity are becoming inadequate. Therefore, exploring various types of frequency regulation resources is essential. However, these resources come with diferent system models, capacities, and response speeds, posing a signifcant challenge to automatic generation control (AGC). To address this issue and enhance the frequency regulation performance of these resources, a novel distributed coordination AGC method is proposed. The proposed method allows each frequency regulation unit to utilize a separate load frequency control (LFC) controller to participate in frequency regulation based on the area control error information calculated by the dispatching center. To ensure the coordination between the heterogeneous frequency regulation resources, an adaptive chaotic gray wolf algorithm is proposed to tune the parameters of the LFC controller. Furthermore, to release the fast frequency regulation ability of high-speed frequency regulation units and better prepare for the next round of frequency regulation service, an event-triggered power dispatching strategy is proposed. Simulation results of a single-area power system with fve diferent frequency regulation units demonstrate the superior performance of the proposed AGC method.

Research on Data Heterogeneity in Enterprise Information Integration

Ruizhen Duan,Zhongwen Wang,Mingshan Chi,Xiaoqiu Xu 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.3

In view of the problem of data heterogeneity in enterprise application integration, we proposed a solution, which is based on XML, WSDL and Web Service technology to achieve the elimination of data heterogeneity, which can reduce the complexity of the system, and has certain significance for the information communication between enterprises and enterprises.

Distributed Secondary Control of AC Microgrid and its Frequency Domain Analysis Considering Time Delay

Cheng Zhiping,Wang Kaifang,Li Zhongwen,Wu Haotian,Zhi Changyi,Zhang Jinbin 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.1

In this paper, distributed secondary control of AC microgrid (MG) is studied and the infuence of communication delay on its control performance is analyzed and verifed. Firstly, a secondary control strategy for the MG is designed to achieve frequency recovery and proportional active power dispatch. Secondly, the stability of the MG system is analyzed in the frequency domain and a rigorous formula is derived to calculate the delay margin for the stability of the distributed secondary control with communication delays. The theoretical calculation results of the stability margin are approximately consistent with the simulation results, with an error of only 1.27%. The efects of the algorithm gains, communication topology, and connection weights on the delay margin are discussed based on the derived formula. The results demonstrate that the algorithm gain is inversely proportional to the delay margin. Changes in the communication topology and connection weights lead to changes in the maximum eigenvalue of the adjacency matrix L, which in turn afects the delay margin. Moreover, the infuence of time-varying delays is considered. The system can tolerate greater time-varying delays than fxed delays. Simulation and experimental results validate the efectiveness and feasibility of the proposed method.

Histone acetyltransferase inhibitors antagonize AMP-activated protein kinase in postmortem glycolysis

Qiong Li,Zhongwen Li,Aihua Lou,Zhenyu Wang,Dequan Zhang,Qingwu W. Shen 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.6

Objective: The purpose of this study was to investigate the influence of AMP-activated protein kinase (AMPK) activation on protein acetylation and glycolysis in postmortem muscle to better understand the mechanism by which AMPK regulates postmortem glycolysis and meat quality. Methods: A total of 32 mice were randomly assigned to four groups and intraperitoneally injected with 5-Aminoimidazole-4-carboxamide1-β-D-ribofuranoside (AICAR, a specific activator of AMPK), AICAR and histone acetyltransferase inhibitor II, or AICAR, Trichostatin A (TSA, an inhibitor of histone deacetylase I and II) and Nicotinamide (NAM, an inhibitor of the Sirt family deacetylases). After mice were euthanized, the Longissimus dorsi muscle was collected at 0 h, 45 min, and 24 h postmortem. AMPK activity, protein acetylation and glycolysis in postmortem muscle were measured. Results: Activation of AMPK by AICAR significantly increased glycolysis in postmortem muscle. At the same time, it increased the total acetylated proteins in muscle 45 min postmortem. Inhibition of protein acetylation by histone acetyltransferase inhibitors reduced AMPK activation induced increase in the total acetylated proteins and glycolytic rate in muscle early postmortem, while histone deacetylase inhibitors further promoted protein acetylation and glycolysis. Several bands of proteins were detected to be differentially acetylated in muscle with different glycolytic rates. Conclusion: Protein acetylation plays an important regulatory role in postmortem glycolysis. As AMPK mediates the effects of pre-slaughter stress on postmortem glycolysis, protein acetylation is likely a mechanism by which antemortem stress influenced postmortem metabolism and meat quality though the exact mechanism is to be elucidated.

Performance Analysis of Wireless Network Aided by Discrete-Phase-Shifter IRS

Rongen Dong,Yin Teng,Zhongwen Sun,Jun Zou,Mengxing Huang,Jun Li,Feng Shu,Jiangzhou Wang 한국통신학회 2022 Journal of communications and networks Vol.24 No.5

Discrete phase shifter of intelligent reflecting surface (IRS) generates phase quantization error (QE) and degrades the receive performance at the receiver. To make an analysis of the performance loss (PL) caused by IRS with phase QE, based on the law of large numbers, the closed-form expressions of signal- to-noise ratio (SNR) PL, achievable rate (AR), and bit error rate (BER) are successively derived under line-of-sight (LoS) channels and Rayleigh channels. Moreover, based on the Taylor series expansion, the approximate simple closed form of PL of IRS with approximate QE is also given. The simulation results show that the performance losses of SNR and AR decrease as the number of quantization bits increases, while they gradually increase with the number of IRS phase shifter elements increases. Regardless of LoS channels or Rayleigh channels, when the number of quantization bits is larger than or equal to 3, the performance losses of SNR and AR are less than 0.23 dB and 0.08 bits/s/Hz, respectively, and the BER performance degradation is trivial. In particular, the performance loss difference between IRS with QE and IRS with approximate QE is negligible when the number of quantization bits is not less than 2.

Physiological and omics analysis of maize inbred lines during late grain development

Jin Xining,Zhai Huijie,Wang Pingxi,Zhang Xiaoxiang,Wu Xiangyuan,Zhang Huaisheng,Chen Shilin,Huang Zhongwen 한국유전학회 2022 Genes & Genomics Vol.44 No.8

Background: There were significant differences in the change of moisture content and grain composition at the late stage of grain development among different maize varieties, but the regulation mechanism is not clear. Objective: To explore the key genes causing the variation in physiological traits of two typical maize inbred lines in late grain development. Methods: The grains at different development stages were selected as materials to determine the content of water, sucrose, starch and ABA. Transcriptomic and proteomic analysis of the materials were performed to screen relevant genes. Results: The grain dehydration rate and the content of sucrose, starch and ABA were showed significant differences between two varieties in the late stage of grain development. The enrichment analysis of common differentially expressed genes (proteins) showed that most of the genes (proteins) were enriched in the extracellular region. The downregulated genes were mainly concentrated in carbohydrate metabolism and lipid metabolism, while the upregulated genes were mainly in response to stress. Furthermore, this study also identified many key candidate genes (dehydrin genes, pathogenesis-related genes, sucrose synthase and secondary metabolites related genes) related to late grain development of maize. Conclusions: The suggested genes related to late grain development of maize can be candidates for further functional study.

Researches on a Novel Severe Plastic Deformation Method Combining Direct Extrusion and Shearings for AZ61 Magnesium Alloy Based on Numerical Simulation and Experiments

Hu Hongjun,Sun Zhao,Ou zhongwen,Wang xiaoqing 대한금속·재료학회 2017 METALS AND MATERIALS International Vol.23 No.3

A new severe plastic deformation method called extrusion-shearing shorten for “ES” has been developed to fabricatethe ultra-fine grained AZ61 magnesium alloys. The correlation theories of ES process have been studiedwhich includes cumulative strain and Zener-Hollomon parameter etc. Simulations of ES process for wroughtAZ61 magnesium alloy have been performed using three-dimensional finite element method. ES dies with onestep shearing and two step shearings have been designed, manufactured and installed onto thermo-mechanicalsimulator and industrial horizontal extruder, respectively. Microstructures evolution has been observed andanalysed. The influences of the ES processes on the grain refinements of AZ61magniesium alloys during multistageprocesses have been investigated. Based on the experimental, simulation and theoretical results, ES processcould increase the cumulative strains enormously and refine grain sizes by direct extrusion and additionalshearings. ES process can produce the serve plastic deformation and improve the volume fraction of dynamicrecrystallization. Continuous dynamic recrystallizaion is the main reason for grain refinements during ES process.