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Spectral Research on an AlGaAs Epitaxial Material for a Terahertz Quantum-cascade Laser
Zhi-Yong Tan,Jun-Cheng Cao 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.60 No.8
The spectral properties of a series of AlGaAs epitaxial films were studied by using a Fourier transform infrared spectrometer with an 80-degree grazing incidence reflection unit. The AlAslike transversal optical phonon was obviously observed in the spectra, but the longitudinal optical phonon was obscured in the transmission spectra. The variation curves for the transversal optical phonon energy were acquired from the two kinds of spectra and were compared with each other and with the early results. A comparison of the results show that the grazing incidence reflection spectrum is better in reflecting the AlAs-like phonon energy of an AlGaAs epitaxial film and could be a supplementary means in the characterization of the material for a terahertz quantum-cascade laser.
Expression profiles of circular RNAs in sheep skeletal muscle
Cao, Yang,You, Shuang,Yao, Yang,Liu, Zhi-Jin,Hazi, Wureli,Li, Cun-Yuan,Zhang, Xiang-Yu,Hou, Xiao-Xu,Wei, Jun-Chang,Li, Xiao-Yue,Wang, Da-Wei,Chen, Chuang-Fu,Zhang, Yun-Feng,Ni, Wei,Hu, Sheng-Wei Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.10
Objective: Circular RNAs (circRNAs) are a newfound class of non-coding RNA in animals and plants. Recent studies have revealed that circRNAs play important roles in cell proliferation, differentiation, autophagy and apoptosis during development. However, there are few reports about muscle development-related circRNAs in livestock. Methods: RNA sequencing analysis was employed to identify and annotate circRNAs from longissimus dorsi of sheep. Reverse transcription followed by real-time quantitative (q) polymerase chain reaction (PCR) analysis verified the presence of these circRNAs. Targetscan7.0 and miRanda were used to analyse the interaction of circRNA-microRNA (miRNA). To investigate the function of circRNAs, an experiment was conducted to perform enrichment analysis hosting genes of circRNAs using gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathways. Results: About 75.5 million sequences were obtained from RNA libraries of sheep skeletal muscle. These sequences were mapped to 729 genes in the sheep reference genome. We identified 886 circRNAs, including numerous circular intronic RNAs and exonic circRNAs. Reverse transcription PCR (RT-PCR) and DNA sequencing analysis confirmed the presence of several circRNAs. Real-Time RT-PCR analysis exhibited resistance of sheep circRNAs to RNase R digestion. We found that many circRNAs interacted with muscle-specific miRNAs involved in growth and development of muscle, especially circ776. The GO and KEGG enrichment analysis showed that hosting genes of circRNAs was involved in muscle cell development and signaling pathway. Conclusion: The study provides comprehensive expression profiles of circRNAs in sheep skeletal muscle. Our study offers a large number of circRNAs to facilitate a better understanding of their roles in muscle growth. Meanwhile, we suggested that circ776 could be analyzed in future study.
AntagomiR-27a Targets FOXO3a in Glioblastoma and Suppresses U87 Cell Growth in Vitro and in Vivo
Ge, Yun-Fei,Sun, Jun,Jin, Chun-Jie,Cao, Bo-Qiang,Jiang, Zhi-Feng,Shao, Jun-Fei Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Objective: To study the effect of the antagomiR-27a inhibitor on glioblastoma cells. Methods: The miR-27a expression level in specimens of human glioblastoma and normal human brain tissues excised during decompression for traumatic brain injury was assessed using qRT-PCR; The predicted target gene of miR-27a was screened out through bioinformatics databases, and the predicted gene was verified using genetic report assays; the effect of antagomiR-27a on the invasion and proliferation of glioma cells was analyzed using MTT assays and 5-ethynyl-2'-deoxyuridine (EdU) labeling. A xenograft glioblastoma model in BALB-c nude mice was established to detect the effect of antagomiR-27a on tumour growth. Results: qRT-PCR results showed that miR-27a significantly increased in specimens from glioblastoma comparing with normal human brain tissues. Th miR-27a inhibitor significantly suppressed invasion and proliferation of glioblastoma cells. FOXO3a was verified as a new target of miR-27a by Western blotting and reporter analyzes. Tumor growth in vivo was suppressed by administration of the miR-27a inhibitor. Conclusion: MiR-27a may be up-regulated in human glioblastoma, and antagomiR-27a could inhibit the proliferation and invasion ability of glioblastoma cells.
Terahertz Computed Tomorgraphy with a Quantum Cascade Laser and a Quantum-well Photodetector
Tao Zhou,Li Gu,Zhi-Yong Tan,Jun Cheng Cao 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.2
In this letter, a terahertz (THz) tomography system based on a quantum cascade laser (QCL)and a quantum-well photodetector (QWP) is demonstrated. The QCL provides a relatively high power (a few microwatts) in a continuous-wave mode at 3.9 THz as a light source, and the QWP provides a narrow response range from 3 to 7 THz with a calibrated peak response of 0.5 A/W under background-limited performance. We employ the widely-used filtered back projection (FBP)and algebraic reconstruction algorithms for terahertz tomography technology. The reconstructed cross-sectional image of a sample has successfully revealed the internal and the external structures with a resolution of around 1.5 mm. This experiment demonstrates that the terahertz QCL and the photodetector are potentially useful for terahertz tomography applications.
Duan-Jian Tao,Yan Dong,Zhi-Jun Cao,Feng-Feng Chen,Xiang-Shu Chen,Kuan Huang 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.41 No.-
A series of sulfonic functionalized ionic liquids (SFILs) with different acidity were designed and preparedfor the synthesis of terpene esters (e.g. geranyl acetate). The effect of acidity of SFILs on their performancewas investigated systematically. It is found that tuning the acidity of SFILs to an appropriate value resultsin not only high conversion of geraniol but also superior selectivity of geranyl acetate. The SFILs can beeasily separated from products byfiltration under room temperature, thus showing good reusability. Furthermore, the kinetics for SFILs in the esterification of geraniol were determined as the basis for futureprocess design.
Rui-fang Liu,Xin Ma,Jun-ci Cao,Shuang-xia Niu,Zhi-gang Wu 한국자기학회 2019 Journal of Magnetics Vol.24 No.2
Amorphous materials have the advantages of high permeability and low core losses. Their application in the motor can reduce the energy consumption and improve the efficiency. To investigate the advantage of amorphous materials on the performance of permanent magnet synchronous motors (PMSMs) at lower speed situation, three 1.5 kW motors used in steering pumps of electric vehicles are analyzed and compared. Two prototypes and the experimental platform are built. The experimental results indicate that the efficiency of the PMSM motor with amorphous materials increases by 1.4 % at 1200 rpm, which shows that amorphous materials can also improve the motor performance at lower speed. To further take advantage of amorphous materials, the particle swarm optimization algorithm is used to optimize the dimensions of amorphous motor and the efficiency is increased by 0.54 %.
Ran An,Shuai Wen,Dong-Li Li,Qiu-Hua Li,Xing-Fei Lai,Wen-Ji Zhang,Ruo-Hong Chen,Jun-Xi Cao,Zhi-Gang Li,Qiu-Sheng Huang,Ling-Li Sun,Shi-Li Sun 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.9
Tea and citrus maxima are natural, medicinal homologous plants, typically used for making beverages, which have anticancer, antiobesity, and antioxidation properties. Green tea, yellow tea, and black tea were combined with citrus maxima to obtain green tea and Citrus maxima (GTCM), yellow tea and Citrus maxima (YTCM), and black tea and Citrus maxima (BTCM). The biochemical components of these mixtures were analyzed, and their possible effects and mechanisms on relieving liver lipid deposition were explored. The tea polyphenols, free amino acids, phenolamine ratio, and caffeine were comparable in YTCM and GTCM, being significantly higher than those in BTCM. In addition, the content of esterified catechins, nonesterified catechins, and total catechins in YTCM was significantly higher than those in GTCM and BTCM. All three mixtures of Citrus maxima tea significantly reduced lipid deposition in HepG2 cells, with GTCM and YTCM being slightly more effective than BTCM. Regarding the possible mechanism, Western blot analysis revealed that the three Citrus maxima tea mixtures could activate the AMPK/ACC signaling pathway, upregulate the expression of p-AMPK, p-ACC, and CPT-1 proteins, and downregulate the expression of SREBP1c and fatty acid synthase proteins to inhibit fat synthesis, thereby relieving lipid deposition in liver cells. In conclusion, as a novel and healthy beverage, Citrus maxima tea has the potential to alleviate liver lipid deposition, and further could be responsible for obesity treatment.