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        Evaluation of Antioxidative Effects of Lactobacillus plantarum with Fuzzy Synthetic Models

        ( Jichun Zhao ),( Fengwei Tian ),( Shuang Yan ),( Qixiao Zhai ),( Hao Zhang ),( Wei Chen ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.7

        Numerous studies suggest that the effects of lactic acid bacteria (LAB) on oxidative stress in vivo are correlated with their antioxidative activities in vitro; however, the relationship is still unclear and contradictory. The antioxidative activities of 27 Lactobacillus plantarum strains isolated from fermented foods were determined in terms of 2,2-diphenyl-1-picrylhydrazyl, hydroxyl radical, and superoxide radical scavenging abilities, reducing activity, resistance to hydrogen peroxide, and ferrous chelating ability in vitro. Two fuzzy synthetic evaluation models, one with an analytic hierarchy process and one using entropy weight, were then used to evaluate the overall antioxidative abilities of these L. plantarum strains. Although there was some difference between the two models, the highest scoring strain (CCFM10), the middle scoring strain (CCFM242), and the lowest scoring strain (RS15-3) were obtained with both models. Examination of the antioxidative abilities of these three strains in D-galactose-induced oxidative stress mice demonstrated that their overall antioxidative abilities in vitro could reveal the abilities to alleviate oxidative stress in vivo. The current study suggests that assessment of overall antioxidative abilities with fuzzy synthetic models can guide the evaluation of probiotic antioxidants. It might be a more quick and effective method to evaluate the overall antioxidative abilities of LAB.

      • KCI등재

        Analysis for forced response of a non-contact piezoelectric driving system modulated by electromagnetic field under coupling excitation

        Jichun Xing,Longwei Zhao,Chonglin Liu 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.4

        For a non-contact piezoelectric driving system modulated by electromagnetic field, the dynamic equations of the driving system under coupling excitation are deduced. Using the Duhamel’s integral, forced response of displacement in the time-domain and frequencydomain were investigated, and the influence of some system parameters on the displacement response is analyzed. The results show that in the same excitation frequency, the displacement responses of the driving beams is the most significant, and the vibration response of the central shaft is relatively less obvious. The larger displacement responses of the driving beam end is beneficial to increasing the step angle of the driving system, and the smaller vibration of the central is beneficial to stable torque output of drive system. Therefore, the design of this structure is more reasonable. The results are useful for design of the operating performance of the driving system.

      • KCI등재

        Ionic Liquid Induced Supramolecular Self-Assembly of Poly(3,4-ethylenedioxythiophene)/ Poly(4-styrenesulfonate) Thin Films with Enhanced Conductivity and Tunable Nanoporosity

        Liping Zhao,Jishan Qiu,Xiaojun Cao,Wenyong Dong,Jichun You,Yongjin LI 한국고분자학회 2013 Macromolecular Research Vol.21 No.4

        We present a facile strategy, for the first time as the best of our known, to prepare high conducting poly(3,4-ethylenedioxythiophene)/poly(4-styrenesulfonate) (PEDOT:PSS) film with a novel nanoporous morphology directly from a commercial PEDOT:PSS dispersion. Both conducting properties and surface morphology of PEDOT:PSS film can be systematically tunable by simply controlling addition of an ionic liquid, 1,3-dihydroxy-2-methylimidazolium bis(trifluoromethylsulfonyl)-imide (DHIL). The electrical conductivity increases from 0.07 for pristine PEDOT:PSS to 55 S cm-1 after addition of 2 wt% DHIL, with no necessary of any further heat treatment, which is around 800 times increase in the electrical conductivity. On the other hand, the discrete compact PEDOT:PSS film is gradually transformed into the nanoporous film with addition of DHIL. It is considered that such size-tunable porous PEDOT:PSS films with high surface area as well as high conductivity combining solution-processibility show great potential in applications that require high interfacial area, such as flexible electronic components, nextgeneration catalytic, and separation supports.

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        Histological Validation of Cardiovascular Magnetic Resonance T1 Mapping for Assessing the Evolution of Myocardial Injury in Myocardial Infarction: An Experimental Study

        Zhang Lu,Yang Zhi-gang,Xu Huayan,Yang Meng-xi,Xu Rong,Chen Lin,Sun Ran,Miao Tianyu,Zhao Jichun,Zhou Xiaoyue,Fu Chuan,Guo Yingkun 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.12

        Objective: To determine whether T1 mapping could monitor the dynamic changes of injury in myocardial infarction (MI) and be histologically validated. Materials and Methods: In 22 pigs, MI was induced by ligating the left anterior descending artery and they underwent serial cardiovascular magnetic resonance examinations with modified Look-Locker inversion T1 mapping and extracellular volume (ECV) computation in acute (within 24 hours, n = 22), subacute (7 days, n = 13), and chronic (3 months, n = 7) phases of MI. Masson’s trichrome staining was performed for histological ECV calculation. Myocardial native T1 and ECV were obtained by region of interest measurement in infarcted, peri-infarct, and remote myocardium. Results: Native T1 and ECV in peri-infarct myocardium differed from remote myocardium in acute (1181 ± 62 ms vs. 1113 ± 64 ms, p = 0.002; 24 ± 4% vs. 19 ± 4%, p = 0.031) and subacute phases (1264 ± 41 ms vs. 1171 ± 56 ms, p < 0.001; 27 ± 4% vs. 22 ± 2%, p = 0.009) but not in chronic phase (1157 ± 57 ms vs. 1120 ± 54 ms, p = 0.934; 23 ± 2% vs. 20 ± 1%, p = 0.109). From acute to chronic MI, infarcted native T1 peaked in subacute phase (1275 ± 63 ms vs. 1637 ± 123 ms vs. 1471 ± 98 ms, p < 0.001), while ECV progressively increased with time (35 ± 7% vs. 46 ± 6% vs. 52 ± 4%, p < 0.001). Native T1 correlated well with histological findings (R2 = 0.65 to 0.89, all p < 0.001) so did ECV (R2 = 0.73 to 0.94, all p < 0.001). Conclusion: T1 mapping allows the quantitative assessment of injury in MI and the noninvasive monitoring of tissue injury evolution, which correlates well with histological findings.

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