Chirality detection of amino acid enantiomers by organic electrochemical transistor

Zhang, Lijun,Wang, Guiheng,Xiong, Can,Zheng, Lei,He, Jianbo,Ding, Yunsheng,Lu, Hongbo,Zhang, Guobing,Cho, Kilwon,Qiu, Longzhen Elsevier 2018 Biosensors & bioelectronics Vol.105 No.-

<P><B>Abstract</B></P> <P>Chiral recognition of α-amino acids is attracting increasing interest due to the importance of α-amino acids in protein metabolism as well as in food products and pharmaceuticals. Organic electrochemical transistors (OECTs) with gate electrodes modified with molecularly imprinted polymer (MIP) films were fabricated and successfully used as highly selective and sensitive chiral recognition biosensors for <SMALL>D/L</SMALL>-tryptophan (<SMALL>D</SMALL> <SMALL>/</SMALL> <SMALL>L</SMALL>-Trp) and <SMALL>D/L</SMALL>-tyrosine (<SMALL>D</SMALL> <SMALL>/</SMALL> <SMALL>L</SMALL>-Tyr). The MIP films, which can specifically recognize and has an electrocatalytic effect on the oxidation of Trp and Tyr, together with the amplification function of an OECT, provide a highly sensitive and selective OECT biosensor. The sensor showed a linear response range for <SMALL>L</SMALL>-Trp and <SMALL>L</SMALL>-Tyr from 300 nM to 10 μM with a sensitivity of 3.19 and 3.64 μA/μM, respectivity. And the detection limit for <SMALL>L</SMALL>-Trp and <SMALL>L</SMALL>-Tyr is of 2 nM and 30 nM (S/N > 3). The selectivity factors of <SMALL>L</SMALL>-Trp, <SMALL>D</SMALL>-Trp, <SMALL>L</SMALL>-Tyr and <SMALL>D</SMALL>-Tyr to their enantiomers are 11.6, 3.5, 14.5 and 2.6, respectively. This method can pave the way for widespread applications of OECT-based sensors in chiral material identification.</P> <P><B>Highlights</B></P> <P> <UL> <LI> An novel chiral recognition MIP-OECT sensor was developed. </LI> <LI> The MIP films showed good performance of selective and electro-catalytic oxidation for Trp and Tyr. </LI> <LI> The MIP films together with the amplification function of an OECT afforded a highly sensitive, selective sensor for chirality detection of amino acid enantiomers. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Genetic parameters for residual feed intake in a random population of Pekin duck

Zhang, Yunsheng,Guo, Zhan Bao,Xie, Ming,Zhang, Zhiying,Hou, Shuisheng Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.2

Objective: The feed intake (FI) and feed efficiency are economically important traits in ducks. To obtain insight into this economically important trait, we designed an experiment based on the residual feed intake (RFI) and feed conversion ratio (FCR) of a random population Pekin duck. Methods: Two thousand and twenty pedigreed random population Pekin ducks were established from 90 males mated to 450 females in two hatches. Traits analyzed in the study were body weight at the 42th day (BW42), 15 to 42 days average daily gain (ADG), 15 to 42 days FI, 15 to 42 days FCR, and 15 to 42 days RFI to assess their genetic interrelationships. The genetic parameters for feed efficiency traits were estimated using restricted maximum likelihood (REML) methodology applied to a sire-dam model for all traits using the ASREML software. Results: Estimates heritability of BW42, ADG, FI, FCR, and RFI were 0.39, 0.38, 0.33, 0.38, and 0.41, respectively. The genetic correlation was high between RFI and FI (0.77) and moderate between RFI and FCR (0.54). The genetic correlation was high and moderate between FCR and ADG (-0.80), and between FCR and BW42 (-0.64), and between FCR and FI (0.49), respectively. Conclusion: Thus, selection on RFI was expected to improve feed efficiency, and reduce FI. Selection on RFI thus improves the feed efficiency of animals without impairing their FI and increase growth rate.

Research on Enhancing the Corrosion Resistance of Concrete In a MgSO 4 Corrosive Environment Using CTF Synergist

Xi Wang,Hongxia Qiao,Yunsheng Zhang,Wenhua Zhang,Cuizhen Xue,Mubita Majory Mundia,Lei Zhang 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.4

Concrete structure is easy to be damaged by corrosion in natural environment. In order to find a new way to improve the corrosion resistance of concrete. In this paper, the effect of Coal Tar Fuel (CTF) synergist on the corrosion resistance of concrete was analyzed by using MgSO4solution with concentration of 5% as corrosion medium. The change rule of concrete pore structure was studied. And the performance of concrete interfacial transition zone (ITZ) is studied. Finally, the effect of CTF synergist on hydration reaction of cementitious materials was revealed. The results show that the addition of 0.7% CTF synergist can significantly enhance the corrosion resistance of concrete, even with 10% reduction in cement dosage. After 28 days of being cured under this dosage, there is 13.54% increase in the proportion of pores with a diameter less than 100 μm and a 5.36% decrease in the proportion of pores with a diameter greater than 600 μm. Meanwhile, the microhardness of ITZ increases by 41.14%, while the width of ITZ decreases by 12.5%. Additionally, there is a reduction in the maximum crack width at the interface between ITZ and aggregate by 1.8 μm. The exothermic reaction of the cementitious material during hydration is more pronounced when the hydration time exceeds one hour.

Study on the Flexural Performance of Prestressed Concrete Solid Square Piles and Resilient Clamping Connections

Yunsheng Xu,Zhongfan Chen,Ji Fan,Zhiqiang Li,Kai Zhang,Xuesong Tu 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.1

The length of a single prestressed square pile is usually between 6 and 15 meters. For square piles larger than 15 meters, increasing the pile length is generally achieved by a mechanical connection. Currently, the longitudinal reinforcement ratios of square piles are the same, resulting in steel waste. To reduce steel usage in prestressed concrete solid square piles and improve construction efficiency, the safe and reliable use of two different reinforced square piles connected by resilient clamping must be ensured. In this paper, the bending test of a single square pile with different reinforcements is initially carried out. Then, the tensile performance of the resilient clamping connection joint is verified, and finally, a bending test is carried out on prestressed square piles with different reinforcements. The load?displacement curves, flexural bearing capacities and crack developments of the components are studied. The test results show that increasing the longitudinal reinforcement ratio of a single prestressed concrete solid square pile improves its crack and bending resistance to a certain extent. Resilient clamping connects the prestressed square piles with the same reinforcement and different reinforcements, and their crack resistance and bending resistance are almost the same, which demonstrates that the resilient clamping connection of different reinforcement square piles has application value. At the end of the test, the joints were intact, and the pile body was damaged before the resilient clamping connections, which indicated that the resilient clamping connections were safe and reliable and could be used as connecting joints for square piles. The failure of square piles goes through three stages: an elastic stage, a working stage with cracks and a failure stage. Compared with a single square pile, there is no obvious yield stage for a resilient clamping connected square pile.

Experimental research on free vibration of curved composite box-girders with corrugated steel webs

Yunsheng Li,Qingnian Dai,Chaoxing Liu,Yanling Zhang 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.41 No.1

The curved composite box-girders (CBGs) with corrugated steel webs (CSWs) have been used widely in bridges due to their great advantages and the demand of the road alignment, but the curvature makes both the static and dynamic behaviors more complex. To research the free vibration performance of the curved CBGs with CSWs, 5 simply-supported test girders were designed with the span-to-radius ratio (λ=L/R), the number of the cells of the box section, and the number of the diaphragms as parameters. The natural frequencies and mode shapes were measured in the experiment. The experimental results were compared with the numerical results using ANSYS software, and a satisfying agreement was obtained. The parametric analysis shows that for the curved CBG with CSWs, the vertical mode shapes are combined flexural and torsion, and the contribution of the torsional effects to the mode shapes and frequencies improve with the increase of λ, which leads to a decrease in the vertical and lateral frequencies and increase in the torsional frequency. The corrugated angle of the steel web has little effect on the natural frequencies of the curved CBGs with CSWs. Increasing the thickness of the steel web and the number of the diaphragms can improve the torsional rigidity of the curved CBG with CSWs effectively; while the deck width has a great contribution on the lateral rigidity.

Fused Heptacyclic-Based Acceptor-Donor-Acceptor Small Molecules: N-Substitution toward High-Performance Solution-Processable Field-Effect Transistors

Zhang, Guobing,Zhao, Yao,Kang, Boseok,Park, Sangsik,Ruan, Jiufu,Lu, Hongbo,Qiu, Longzhen,Ding, Yunsheng,Cho, Kilwon American Chemical Society 2019 Chemistry of materials Vol.31 No.6

<P>Although various donor-acceptor (D-A) small molecules with high power conversion efficiency have been reported, D-A small molecules with high field-effect mobility are still rare. In this work, two new A-D-A small molecules with a rigid indacenodithieno[3,2-<I>b</I>]thiophene (<B>IDTT</B>) moiety as the central core and both ends capped with strong electron-withdrawing indole-2,3-dione (<B>IDD</B>) and N-substituted pyrrolo[2,3-<I>b</I>]pyridine-2,3-dione (<B>IDD-N</B>) were synthesized and characterized for applications in solution-processable organic field-effect transistors (OFETs). A N atom was introduced to the <B>IDD</B> units to enhance the planarity and structural ordering by noncovalent interactions, leading to a dramatic effect on the small molecule. The unsubstituted small molecule (<B>IDTT-IDD</B>) did not show any field-effect performance, whereas an encouraging hole mobility of 7.7 cm<SUP>2</SUP> V<SUP>-1</SUP> s<SUP>-1</SUP> with an average mobility of 6.1 cm<SUP>2</SUP> V<SUP>-1</SUP> s<SUP>-1</SUP> was obtained for solution-processable OFETs based on the N-substituted one (<B>IDTT-IDD-N</B>). This work provided a simple and effective molecular strategy for the design of D-A small molecules for high-performance solution-processable OFETs.</P> [FIG OMISSION]</BR>

GEOLOGICAL SCIENCES SESSION : Manzhouli-Suifenhe Transect ( M-S GGT ) , P.R.China

장이협(Zhang Yixia),손운생(Sun Yunsheng) 자연사.미래환경학회(구.자연사환경학회) 1993 KOREA-CHINA SYMPOSIUM ON NATURAL HISTORY AND ENVIR Vol.- No.-

SPATIAL-BASED PREDICTIVE CONTROL FOR VEHICLE COLLISION AVOIDANCE BY STEERING MANEUVERS

Shaosong Li,Yunsheng Tian,Xiaofeng Yue,Niaona Zhang,Shujun Wang 한국자동차공학회 2022 International journal of automotive technology Vol.23 No.1

A hierarchical vehicle collision avoidance control method based on model predictive control is presented in this study. In the upper level of the controller, a spatial-based two-degree-of-freedom vehicle model is used for dynamic path planning to decrease the computational burden of the algorithm. Obstacles and road boundaries are translated into spatialbased constraints on system states. An objective function that considers tire adhesion margin is introduced to the path tracking controller to enhance vehicle safety. Meanwhile, the dynamic constraints of vehicle lateral acceleration, sideslip, and tire slip angles are designed in accordance with the tire-road adhesion coefficient. A time-based nonlinear model predictive controller is also designed and compared with the proposed method to verify the effectiveness and superiority of the latter. Theoretical analyses and simulation results indicate that the proposed collision avoidance control system has good ollision avoidance effect.

Tuning the Energy Levels of Aza-Heterocycle-Based Polymers for Long-Term <i>n</i>-Channel Bottom-Gate/Top-Contact Polymer Transistors

Ma, Suxiang,Zhang, Guobing,Wang, Feifei,Dai, Yanrong,Lu, Hongbo,Qiu, Longzhen,Ding, Yunsheng,Cho, Kilwon American Chemical Society 2018 Macromolecules Vol.51 No.15

<P>Conjugated polymer-based organic thin film transistors (OTFTs) have received tremendous attention due to their potential applications. In addition to their high performances, air stability is also essential for application and another main property that OTFTs have. In this paper, three aza-heterocycle (BABDF)-based polymers were designed and synthesized using strong donor thiophene-vinylene-thiophene (TVT), weak donor thiophene-cyanovinylene-thiophene (TCNT), and weak acceptor dithiazole (TZ) as co-units. The lowest unoccupied molecular orbital (LUMO)/highest occupied molecular orbital (HOMO) energy levels were effectively lowered by introducing TCNT and TZ units, especially for PBABDF-TZ, for which the too much deep LUMO/HOMO energy levels of −4.28/-6.06 eV were obtained. These levels are low enough for air-stable electron transport and large enough for the hole injection barriers in OTFTs. Consequently, the unencapsulated bottom-gate/top-contact (BG/TC) devices exhibited unipolar electron transport under air conditions. Furthermore, these devices had high air stability and maintained unipolar electron transport with a mobility of up to 0.01 cm<SUP>2</SUP> V<SUP>-1</SUP> s<SUP>-1</SUP> during the one-year characterization period. Very low LUMO and HOMO levels were necessary for electron transport and the hole barriers, respectively, and both were important for long-term, air-stable <I>n</I>-channel polymer transistors.</P> [FIG OMISSION]</BR>

Acylation of salicylamide to 5-acetylsalicylamide using ionic liquids as dual catalyst and solvent

Weiguang Chen,Yunsheng Zhang,Zhangzhun Lu,Aili Wang,Yutang Shen,Tingshun Jiang,Longbao Yu,Hengbo Yin 한국공업화학회 2010 Journal of Industrial and Engineering Chemistry Vol.16 No.5

The Lewis acidic ionic liquids, 1-butyl-3-methylimidazolium chloroaluminate ([BMIM]Cl-nAlCl3) and Nbutylpyridinium chloroaluminate ([BPy]Cl-nAlCl3), were used as both catalyst and solvent in Friedel–Crafts acylation of salicylamide with acetyl chloride to 5-acetylsalicylamide. The Lewis acidic ionic liquids, substituting for the conventional carcinogenic nitrobenzene solvent and anhydrous AlCl3catalyst, showed excellent catalytic activity in the acylation of salicylamide to 5-acetylsalicylamide. When [BMIM]Cl-2AlCl3 was used as the catalyst, the yield of 5-acetylsalicylamide reached 81.3%. When [BPy]-2AlCl3 was used as the catalyst, the maximum yield of 5-acetylsalicylamide was 89.2%. The content of AlCl3 and the structure of the cations in the ionic liquids had synergistic effect on the acylation reaction. 2010 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.