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      • KCI등재후보

        Comparison of Acupuncturing Hegu (LI4) by Metal or Laser Needle on Facial Blood Perfusion Using Laser Speckle Technique

        Yuying Tian,Tao Huang,Gerhard Litscher,Lu Wang,Guangjun Wang,Shuyong Jia,Yuqing Zhang,Weibo Zhang 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.3

        Aim: To compare the difference of remote effects of acupuncture between metal needle and laser needle on facial blood perfusion (FBP). Methods: Hand acupuncture and laser-needle acupuncture were randomly used on Hegu (LI4)in 20 healthy volunteers. FBP was observed by speckle contrast imager before, during, and after the acupunctures. Results: For hand acupuncture there were gradual increases on the nose and left and right visor areas (p < 0.05 or p < 0.01) during the acupuncture and on an immediate increase (p < 0.01) that remained constant during the acupuncture on the forehead area but no significant increase on mouth area. During laser-needle acupuncture, on the other hand, there was a tendency of increase on the nose, left visor, and right visor areas but these were non significant. Conclusion: Hand acupuncture can influence FBP in remote places connected by meridians.

      • KCI등재

        Nanostructures and nanomechanical properties of ion-irradiated HOPG

        Zhou Yuying,Wang Ying,Lei Qiantao,Huang Qing,Zhang Wei,Yan Long 한국탄소학회 2021 Carbon Letters Vol.31 No.4

        Highly Oriented Pyrolytic Graphite (HOPG) was half covered using aluminum foil and exposed to irradiation with 70 keV C+ ions at room temperature (~25 ℃). The surface layer (height=178.3±4.7 nm) of the irradiated area was destroyed, many nano-sized dendritic protrusions were observed and smooth inner layer was exposed. The peak area ratio (ID/IG) in Raman spectra increased after ion irradiation, indicating that a change in atomic structure and transformation from the sp2 to sp3 phase. The mechanical properties were explored using atomic force microscopy in peakforce mode, which revealed that the Young’s modulus of the exposed inner layer was similar to unirradiated area, while the Young’s modulus of the dendritic protrusions was higher. There fndings provid

      • KCI등재

        A Review on Intelligent Scheduling and Optimization for Flexible Job Shop

        Bin Jiang,Yajie Ma,Lijun Chen,Binda Huang,Yuying Huang,Li Guan 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.10

        Flexible job shop scheduling problem is a NP-hard combinatorial optimization problem, which has significant applications in the field of workshop scheduling and intelligent manufacturing. Due to its complexity and significance, lots of attention have been paid to tackle this problem. This paper reviews some of the researches on this problem, by presenting and classifying the different criteria, constraints, and solution approaches. The existing solution methods for the flexible job shop scheduling problem in this literature are classified into exact algorithms, heuristics, and meta-heuristics, which are thoroughly reviewed. Particularly, the paper highlights the flexible job shop scheduling problem in the context of dynamic events and preventive maintenance. These dynamic events, such as machine breakdowns and unexpected changes in job requirements, present additional challenges to the scheduling problem. Furthermore, this paper analyzes the development trends in the manufacturing industry and summarizes detailed future research opportunities for the flexible job shop scheduling problem.

      • SCIESCOPUSKCI등재

        An Engineered Outer Membrane-Defective Escherichia coli Secreting Protective Antigens against Streptococcus suis via the Twin-Arginine Translocation Pathway as a Vaccine

        ( Wenyu Li ),( Fan Yin ),( Zixuan Bu ),( Yuying Liu ),( Yongqing Zhang ),( Xiabing Chen ),( Shaowen Li ),( Lu Li ),( Rui Zhou ),( Qi Huang ) 한국미생물 · 생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.3

        Live bacterial vector vaccines are one of the most promising vaccine types and have the advantages of low cost, flexibility, and good safety. Meanwhile, protein secretion systems have been reported as useful tools to facilitate the release of heterologous antigen proteins from bacterial vectors. The twin-arginine translocation (Tat) system is an important protein export system that transports fully folded proteins in a signal peptide-dependent manner. In this study, we constructed a live vector vaccine using an engineered commensal Escherichia coli strain in which amiA and amiC genes were deleted, resulting in a leaky outer membrane that allows the release of periplasmic proteins to the extracellular environment. The protective antigen proteins SLY, enolase, and Sbp against Streptococcus suis were targeted to the Tat pathway by fusing a Tat signal peptide. Our results showed that by exploiting the Tat pathway and the outer membrane-defective E. coli strain, the antigen proteins were successfully secreted. The strains secreting the antigen proteins were used to vaccinate mice. After S. suis challenge, the vaccinated group showed significantly higher survival and milder clinical symptoms compared with the vector group. Further analysis showed that the mice in the vaccinated group had lower burdens of bacteria load and slighter pathological changes. Our study reports a novel live bacterial vector vaccine that uses the Tat system and provides a new alternative for developing S. suis vaccine.

      • KCI등재

        SALT-INDUCED CHLOROPLAST PROTEIN (SCP) is Involved in Plant Tolerance to Salt Stress in Arabidopsis

        Yong Zhuang,Yangxuan Liu,Yuxiang Li,Ming Wei,Yuying Tang,Penghui Li,Zhijian Liu,Hui Li,Weizao Huang,Songhu Wang 한국식물학회 2019 Journal of Plant Biology Vol.62 No.6

        Soil salinization threats the agricultural productionand food security worldwide. Salt stress induced plantsenescence and chloroplast degradation. However, it remainslargely unknown how the chloroplast-localized proteins affectplant response to salt stress. Here, we characterized a novelgene (At5g39520) in Arabidopsis, which is induced by saltstress and encodes a chloroplast-localized protein. Thus, thisgene was named SALT-INDUCED CHLOROPLAST PROTEIN(SCP). A T-DNA insertion mutant of SCP gene (scp-1)showed the enhanced tolerance to salt stress, as indicated bythe increased survival rates, fresh weights and chlorophyllcontents compared with wild type plants under salt treatment. Salt-induced leaf senescence was also delayed in scp-1 mutant. The scp-1 complementation line and SCP overexpressionlines displayed the hypersensitivity to salt stress. The qRTPCRanalysis indicated that the transcripts of CHLOROPLASTVESICULATION (CV), which mediates stress-inducedchloroplast degradation, were altered in scp-1 mutant andSCP overexpression lines. Taken together, our results suggestthat SCP gene plays a negative role in response to salt stress andhas potential application for genetic modification of improvingplant tolerance to salt stress.

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