Application of Biophysical Properties of Meridians in the Visualization of Pericardium Meridian

Xiong Feng,Xu Ruimin,Li Tongju,Wang Jinyu,Hu Qingchuan,Song Xiaojing,Wang Guangjun,Su Huanhuan,Jia Shuyong,Wang Shuyou,Zhu Zongxiang,Zhang Weibo 사단법인약침학회 2023 Journal of Acupuncture & Meridian Studies Vol.16 No.3

Background: The biophysical properties of the meridian system, an important concept of traditional Chinese medicine, include low impedance, resounding voice, and high acoustic conductance, all of which are helpful for elucidating the essence of meridians. Objectives: To visualize the human pericardium meridian (PC) based on the resounding voice property of meridians. Methods: Visualization of the PC was performed by injection of fluorescein sodium at the PC6 acupoint (Neiguan) on the PC. Before injection, percussion active points (PAPs) were identified by the virtue of their resounding voice properties. After injection, the trajectories of fluorescein migration throughout the body surface were recorded and analyzed. The distribution of fluorescein in the tissue was further studied using cross-sections of hind limbs of mini-pigs, in which fluorescein was injected into low impedance points. Results: The identified PAP lines were colocalized with PC. Following intradermal fluorescein injection, 1-3 fluorescent lines, which were unrelated to the arm veins, were observed in 7 of 10 participants; 85.4% of fluorescent signals were coincident with PAPs and their intensity had a negative correlation with the body mass index (r = –0.56, p = 0.045). Cross-sections showed a Y-shaped fluorescence pattern where the two migration lines on the surface were the two vertices of the “Y.” Conclusion: The trajectories of fluorescein in the body are suggestive of the anatomical structure of meridians. The PC is related to the deep horizontal interstitial channels that connect to the body surface through vertical interstitial spaces. These biophysical properties and techniques for meridian visualization are valuable for revealing the anatomical structure of meridians.

Homomorphic Subspace MAC Scheme for Secure Network Coding

Guangjun Liu,Xiao Wang 한국전자통신연구원 2013 ETRI Journal Vol.35 No.1

Existing symmetric cryptography-based solutions against pollution attacks for network coding systems suffer various drawbacks, such as highly complicated key distribution and vulnerable security against collusion. This letter presents a novel homomorphic subspace message authentication code (MAC) scheme that can thwart pollution attacks in an efficient way. The basic idea is to exploit the combination of the symmetric cryptography and linear subspace properties of network coding. The proposed scheme can tolerate the compromise of up to r–1 intermediate nodes when r source keys are used. Compared to previous MAC solutions, less secret keys are needed for the source and only one secret key is distributed to each intermediate node.

Effect of bogie fairings on the snow reduction of a high-speed train bogie under crosswinds using a discrete phase method

Guangjun Gao,Yani Zhang,Jie Zhang,Fei Xie,Yan Zhang,Jiabin Wang 한국풍공학회 2018 Wind and Structures, An International Journal (WAS Vol.27 No.4

This paper investigated the wind-snow flow around the bogie region of a high-speed train under crosswinds using a coupled numerical method of the unsteady Realizable k-ε turbulence model and discrete phase model (DPM). The flow features around the bogie region were discussed and the influence of bogie fairing height on the snow accumulation on the bogie was also analyzed. Here the high-speed train was running at a speed of 200 km/h in a natural environment with the crosswind speed of 15 m/s. The mesh resolution and methodology for CFD analysis were validated against wind tunnel experiments. The results show that large negative pressure occurs locally on the bottom of wheels, electric motors, gear covers, while the positive pressure occurs locally on those windward surfaces. The airflow travels through the complex bogie and flows towards the rear bogie plate, causing a backflow in the upper space of the bogie region. The snow particles mainly accumulate on the wheels, electric motors, windward sides of gear covers, side fairings and back plate of the bogie. Longer side fairings increase the snow accumulation on the bogie, especially on the back plate, side fairings and brake clamps. However, the fairing height shows little impact on snow accumulation on the upper region of the bogie. Compared to short side fairings, a full length side fairing model contributes to more than two times of snow accumulation on the brake clamps, and more than 20% on the whole bogie.

Optimization of the anti-snow performance of a high-speed train based on passive flow control

Guangjun Gao,Zhen Tian,Jiabin Wang,Yan Zhang,Xinchao Su,Jie Zhang 한국풍공학회 2020 Wind and Structures, An International Journal (WAS Vol.30 No.4

In this paper, the improvement of the anti-snow performance of a high-speed train (HST) is studied using the unsteady Reynolds-Averaged Navier-Stokes simulations (URANS) coupled with the Discrete Phase Model (DPM). The influences of the proposed flow control scheme on the velocity distribution of the airflow and snow particles, snow concentration level and accumulated mass in the bogie cavities are analyzed. The results show that the front anti-snow structures can effectively deflect downward the airflow and snow particles at the entrance of the cavities and alleviate the strong impact on the bogie bottom, thereby decrease the local accumulated snow. The rotational rear plates with the deflecting angle of 45° are found to present well deflecting effect on the particles’ trajectories and force more snow to flow out of the cavities, and thus significantly reduce the accretion distribution on the bogie top. Furthermore, running speeds of HST are shown to have a great effect on the snow-resistance capability of the flow control scheme. The proposed flow control scheme achieves more snow reduction for HST at higher train’s running speed in the cold regions.

Effect of bogie fairings on the snow reduction of a high-speed train bogie under crosswinds using a discrete phase method

Gao, Guangjun,Zhang, Yani,Zhang, Jie,Xie, Fei,Zhang, Yan,Wang, Jiabin Techno-Press 2018 Wind and Structures, An International Journal (WAS Vol.27 No.4

This paper investigated the wind-snow flow around the bogie region of a high-speed train under crosswinds using a coupled numerical method of the unsteady Realizable $k-{\varepsilon}$ turbulence model and discrete phase model (DPM). The flow features around the bogie region were discussed and the influence of bogie fairing height on the snow accumulation on the bogie was also analyzed. Here the high-speed train was running at a speed of 200 km/h in a natural environment with the crosswind speed of 15 m/s. The mesh resolution and methodology for CFD analysis were validated against wind tunnel experiments. The results show that large negative pressure occurs locally on the bottom of wheels, electric motors, gear covers, while the positive pressure occurs locally on those windward surfaces. The airflow travels through the complex bogie and flows towards the rear bogie plate, causing a backflow in the upper space of the bogie region. The snow particles mainly accumulate on the wheels, electric motors, windward sides of gear covers, side fairings and back plate of the bogie. Longer side fairings increase the snow accumulation on the bogie, especially on the back plate, side fairings and brake clamps. However, the fairing height shows little impact on snow accumulation on the upper region of the bogie. Compared to short side fairings, a full length side fairing model contributes to more than two times of snow accumulation on the brake clamps, and more than 20% on the whole bogie.

Fibroblast Activation Protein-Responsive Peptide Nanocarrier Deliver BET Inhibitor to Reduce ECM in Pancreatic Cancer and Enhance the Efficacy of Chemotherapy

Yazhou Wang,Chong Du,Xiaodong Tian,Guangjun Nie,Yinmo Yang 대한외과학회 2018 대한외과학회 학술대회 초록집 Vol.2018 No.11

The local time of the linear self-attracting diffusion driven by weighted fractional Brownian motion

Qin Chen,Guangjun Shen,Qingbo Wang 대한수학회 2020 대한수학회보 Vol.57 No.3

In this paper, we introduce the linear self-attracting diffusion driven by a weighted fractional Brownian motion with weighting exponent $a>-1$ and Hurst index $|b|<a+1,0<b<1$, which is analogous to the linear fractional self-attracting diffusion. For the 1-dimensional process we study its convergence and the corresponding weighted local time. As a related problem, we also obtain the renormalized intersection local time exists in $L^2$ if $\text{max}\{a_1+b_1,a_2+b_2\}<0$.

THE LOCAL TIME OF THE LINEAR SELF-ATTRACTING DIFFUSION DRIVEN BY WEIGHTED FRACTIONAL BROWNIAN MOTION

Chen, Qin,Shen, Guangjun,Wang, Qingbo Korean Mathematical Society 2020 대한수학회보 Vol.57 No.3

In this paper, we introduce the linear self-attracting diffusion driven by a weighted fractional Brownian motion with weighting exponent a > -1 and Hurst index |b| < a + 1, 0 < b < 1, which is analogous to the linear fractional self-attracting diffusion. For the 1-dimensional process we study its convergence and the corresponding weighted local time. As a related problem, we also obtain the renormalized intersection local time exists in L² if max{a₁ + b₁, a₂ + b₂} < 0.

Is There Volume Transmission Along Extracellular Fluid Pathways Corresponding to the Acupuncture Meridians?

Weibo Zhang,Ze Wang,Shuyong Jia,Yuying Tian,Guangjun Wang,Hongyan Li,Kjell Fuxe 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.1

Volume transmission is a new major communication signaling via extracellular fluid (interstitial fluid) pathways. It was proposed by the current authors that such pathways can explain the meridian phenomena and acupuncture effects. To investigate whether meridian-like structures exist in fish body and operate via volume transmission in extracellular fluid pathways, we injected alcian blue (AB) under anesthesia into Gephyrocharax melanocheir, which has a translucent body. The migration of AB could be seen directly and was recorded by a digital camera. The fish was then embedded and cut transversely to observe the position of tracks in three dimensions. Eight longitudinal threadlike blue tracks were recognized on the fish. The positions of these threadlike tracks were similar to meridians on the human body. Transverse sections showed that these tracks distributed to different layers of distinct subcutaneous loose connective tissues and intermuscular septa. Lymphatic vessels were sometimes associated with the extracellular blue tracks where the migration of AB occurred. Extracellular fluid pathways were found on fish through their transport of AB. These pathways operating via volume transmission appeared to be similar in positions and functions to the acupuncture meridians in Chinese medicine.

Comparison of Acupuncturing Hegu (LI4) by Metal or Laser Needle on Facial Blood Perfusion Using Laser Speckle Technique

Yuying Tian,Tao Huang,Gerhard Litscher,Lu Wang,Guangjun Wang,Shuyong Jia,Yuqing Zhang,Weibo Zhang 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.3

Aim: To compare the difference of remote effects of acupuncture between metal needle and laser needle on facial blood perfusion (FBP). Methods: Hand acupuncture and laser-needle acupuncture were randomly used on Hegu (LI4)in 20 healthy volunteers. FBP was observed by speckle contrast imager before, during, and after the acupunctures. Results: For hand acupuncture there were gradual increases on the nose and left and right visor areas (p < 0.05 or p < 0.01) during the acupuncture and on an immediate increase (p < 0.01) that remained constant during the acupuncture on the forehead area but no significant increase on mouth area. During laser-needle acupuncture, on the other hand, there was a tendency of increase on the nose, left visor, and right visor areas but these were non significant. Conclusion: Hand acupuncture can influence FBP in remote places connected by meridians.