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      • Association Between the hsa-mir-27a Variant and Breast Cancer Risk: a Meta-analysis

        Wang, Bin,Ma, Ning,Wang, Yajie Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

        Introduction: Although a number of studies were published in the past several years on associations between hsa-mir-27a and cancer risk, the findings remain conflicting rather than conclusive. To derive a more precise effect on the association between SNP hsa-mir-27a rs895819 and breast cancer risk, we conducted a meta-analysis for the first time. Materials and Methods: Through retrieval from PubMed for the period up to August 2012, a total of four studies were identified with 3,287 cases and 4,298 controls for SNP hsa-mir-27a rs895819. We calculated summary odds ratio (ORs) and corresponding 95% confidence intervals (CIs) using a fixed effects model (when the heterogeneity was absent, P>0.10). Otherwise, the random-effects model was used. Results: We found that hsa-mir-27a rs895819 polymorphism also did not reveal any relationship with breast cancer susceptibility (AG versus AA: OR = 0.98; 95%CI, 0.73-1.32; GG versus AA: OR = 0.86; 95% CI, 0.72-1.03; AG/GG versus AA: OR = 0.92; 95% CI, 0.74-1.14), while significantly decreased risk was found among Europeans in AG versus AA and AG/GG versus AA models tested (AG versus AA: OR = 0.83; 95%CI, 0.72-0.97; GG versus AA: OR = 0.86; 95% CI, 0.71-1.05; AG/GG versus AA: OR = 0.84; 95% CI, 0.75-0.94). Conclusion: These findings suggest that hsa-mir-27a rs895819 polymorphism may play an important role in breast cancer development.

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        A Review on Intelligent Scheduling and Optimization for Flexible Job Shop

        Bin Jiang,Yajie Ma,Lijun Chen,Binda Huang,Yuying Huang,Li Guan 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.10

        Flexible job shop scheduling problem is a NP-hard combinatorial optimization problem, which has significant applications in the field of workshop scheduling and intelligent manufacturing. Due to its complexity and significance, lots of attention have been paid to tackle this problem. This paper reviews some of the researches on this problem, by presenting and classifying the different criteria, constraints, and solution approaches. The existing solution methods for the flexible job shop scheduling problem in this literature are classified into exact algorithms, heuristics, and meta-heuristics, which are thoroughly reviewed. Particularly, the paper highlights the flexible job shop scheduling problem in the context of dynamic events and preventive maintenance. These dynamic events, such as machine breakdowns and unexpected changes in job requirements, present additional challenges to the scheduling problem. Furthermore, this paper analyzes the development trends in the manufacturing industry and summarizes detailed future research opportunities for the flexible job shop scheduling problem.

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        Policy Iteration Based Online Adaptive Optimal Fault Compensation Control for Spacecraft

        Yanbin Du,Bin Jiang,Yajie Ma 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.4

        In this paper, a novel online adaptive optimal fault-tolerant control (FTC) scheme based on policy iteration (PI) algorithm is developed for the spacecraft attitude angular velocity tracking control with actuator faults. First, for the fault-free attitude dynamic model, an adaptive optimal controller is designed based on PI algorithm to solve the Hamilton-Jacobi-Bellman (HJB) equation. In this process of solving, the value function is approximated by means of a critic neural network (NN). Then, a novel adaptive compensation law is proposed for estimation of actuator faults. The closed-loop system is proved to be uniformly ultimately bounded (UUB) via the Lyapunov’s method. Finally, the effectiveness of the proposed control scheme is evaluated via simulation experiments.

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        Crystallization and Mechanical Properties of Continuous Carbon Fiber Reinforced Polyether-ether-ketone Composites

        Kaili Zhu,Hongsheng Tan,Yajie Wang,Changheng Liu,Xiaomin Ma,Jie Wang,Haini Xing 한국섬유공학회 2019 Fibers and polymers Vol.20 No.4

        The effect of two different continuous carbon fibers (CCF1 and CCF2) with different material properties onstructure-properties of continuous carbon fibers reinforced polyether-ether-ketone prepreg tapes (CCF/PEEKPT) prepared bya wet powder impregnation process were investigated. The effects of fiber content on the tensile properties, dynamicmechanical behavior, crystallization melting behavior and fracture morphology of prepared prepreg tapes were performed bythe dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC) and scanning electron microscope (SEM)etc. The results showed that, the tensile strength of CCF1/PEEKPT increased with increasing of the carbon fiber contentwithin 50-75 wt%. Meanwhile, the tensile strength of 50-65 wt% CCF2/PEEKPT had the same change trend, but thendecreased when the fiber content of composites was higher than 65 wt%. The storage modulus (E′) of composites increasedwith adding content of carbon fiber. The composites still maintained high deformation resistance when the temperature roseto 290 oC. Compared with pure PEEK, the crystallinity and crystallization rate of the composites both increased with theoccurrence of fiber inducing PEEK crystallization, but the crystallization onset temperature, crystallization temperature andmelting temperature of CCF/PEEKPT moved to low temperatures with adding of fiber content. In general, these observationssuggested that CCF hindered the movement of the polymer chain segment and constrained the spherulites growth of PEEKfor CCF/PEEKPT.

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