간 및 자궁에 전이된 췌장의 Somatostatinoma

김태유,박영이,임영혁,허대석,방영주,김노경,김선희,김철우 대한내과학회 1993 대한내과학회지 Vol.44 No.5

저자등은 췌장 부위의 종양과 간과 자궁으로의 전이가 있으면서, 일반적인 췌담관계의 악성 종양과는 다른 임상경과를 갖고, 면역 화학적 조직 검사와 혈장 somatostatin의 측정으로 입증된 somatostatinoma 1예를 경험하여 보고하는 바이다. Somatostatinoma, a rare endocrine tumor, is characterized by diarrhea, steatorrhea, diagetes, and cholelithiasis due to excessive production of somatostatin. We report a case of a 32-year-old woman with pancreatic somatostatinoma that methastasized to the liver and uterus. The patient first presented with jaundice and diarrhea, and subsequently ascites and vaginal bleeding. The diagnosis was made by the pathologic examination, immunohistochemistry, and elevated plasma level of somatostatin. The patient was transiently improved with recombinant γ-interferon therapy.

白鼠 頭蓋骨膜의 皮下와 筋肉內에서 新骨形成에 對한 比較 硏究

金東九,姜大榮 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1

Histologically, an experiment(Huggins, 1931) has been performed to elucidate the potential of ectopic new bone formation from the transitional epithelium of urinary tract. The purpose of the present investigation was to study the cellular reaction in heterotopic osteogenesis following implantation of pericranium to subcutaneous tissue and intramuscular region and to examine the morphology of these bone related to time. The specimen taken from all experimental animals were fixed in 10% neutral formalin, embedded in paraffin wax, sectioned at a thickness of 5u, and stained with hematoxylin-eosin for general histologic findings. Observation was made of morphological changes in the collagin fiber, capillary vessels, osteoid tissue and osteoblst arrangement, and grossly observed thickness, arrangement and configuration of new bone. The result are as follows; 1. The new bone formation was better in subcutaneous implantation than intramuscular implantation. 2. The configuration of new bone was superior in groups which were covered to silastic block with pericranium. 3. The inflammatory reaction was nearly subside within two weeks in B2 but C2 ,was prolong to pseudocapsule formation and severe inflammatry reaction to three weeks. 4. The configuration of new bone formation of B1 and C1 were visible to irregular direction and irregular thickness but B2 and C2 were regular form and thickness, and so these were possible to use in reconstructive surgery. 5. The pericranium of control group was severe adhesive to dura at three weeks and new bone formation that was occupying to iatrogenic skull defect. The possibility of producing bone from a malleable soft tissue source could offer a solution to many reconstructive problems of head and neck merits further study.

Methexymethyl sulfide를 이용한 합성연구

김정순,고영관,김대광,윤세중 공주대학교 기초과학연구소 1992 論文集 Vol.30 No.1

For the preparation of broad range of substituted aryl derivatives from the bromophenyl methoxymethyl sulfide and the bromobenzyl methoxymethyl sulfide, various functional groups such as alkyl, ester and haloketone could be easily introduced in the aromatic methoxymethyl sulfides by treatment with various electrophiles. Substituted methoxymethyl phenyl sulfides were converted to the arenesulfonyl chlorides with chlorine in water-dichloromethane at 5∼10℃. And substituted benzyl methoxymethyl sulfides were also converted to the arylmethanesulfonyl chlorides with N-chlorosuccinimide in aqueous acetic acid, at 5∼10℃.

위절제술 후 발생한 유미성 복수 -증례 보고-

윤효영, 송영진, 류동희, 김대훈 충북대학교 의과대학 충북대학교 의학연구소 2011 忠北醫大學術誌 Vol.21 No.2

-본문참고-

들깨(Perilla) 品種改良 및 育成에 관한 硏究(Ⅰ) : 施肥水準 및 栽植密度 試驗 Effect of Fertilizer application and Planting density on Perilla

金正基,孫賢秀,安始榮,鄭大守 東亞大學校 1978 東亞論叢 Vol.15 No.2

1977年 本大學校 農科大學에서 들깨栽培에 대한 施肥適量 및 栽培密植密度에 관한 試驗을 實施한 결과는 다음과 같았다. 1. ?酸質 肥料는 10a當 7kg을 施用하는 것이 效果的이었다. 2. 可里 肥料는 10a當 3kg을 施用하는 것이 들깨의 收量을 높여 주었다. 3. 本試驗에서 石?의 施用效果는 별로 없었다. 4. 들깨의 栽植密度는 60cm X 20cm가 가장 收量이 높았다. Factorial experiment was carried out in to determine the adequated amount of fertilizer and planting density for perilla breeding, and the results obtained were as follows; 1) 7kg per 10a of P²O fertilization was found reasonable. 2) 3kg per 10a of potash fertilization was effective for increasing the yields of perilla seed. 3) No effect was recognized in clcim application. 4) Adequate planting density was 60cmX20cm in order to increase the yields.

습관성 흡연여성에서 후측 수부에 발생한 Buerger씨병

김삼,이남호,육청미,최영진,백대균,홍경순,두영철,한규록,오동진,유규형,임종윤,이광학,이영 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.7

加水分解 牛皮粉의 飼料的 價値에 관한 硏究

金大鎭,孟元在,高永杜 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-

Protein quality of hydrolyzed cattle skin meal was estimated by the pepsin-HCL digestion with various concentration and incubation time, and by chemical score to determine the limiting amino acids. Protein efficiency ratio(PER), net protein ratio(NPR) and net protein utilization(NPU) were also studied with chicks fed semipurified diet with and without supplementation of the limiting amino acids. Broiler chick growth trials were also conducted to determine the supplementation level of hydrolyzed cattle skin meal by replacing with soybean meal and feather meal. The results are summarized as follows: 1. Protein digestibility of hydrolyzed cattle skin meal was 66.31%, 80.69%, 83.72%, 84.65%, and 87.45%, respectively for 4, 8, 12, 16 and 20 hours incubation of 0.2% pepsin-HCl. Protein digestibility maintained above 80% after 8hours incubation and increased by increasing incubation time. 2. Protein digestibilities of hydrolyzed cattle skin meal incubated for 16 hours at 0.2%, 0.1%, 0.05%, 0.025%, and 0.0125% pepsin-HCl solution were 85.10%, 82.08%, 76.18%, 74.67% and 64.82%, respectively. 3. Chemical scores of methionine, isoleucine, threonine, leucine and histidine estimated based on NRC(1977) broiler(03 weeks) feeding standard were 27%, 38%, 44%, 48% and 51%, respectively 4. Growth rate, feed intake and feed conversion were improved by the addition of the limiting amino acids in the hydrolyzed cattle skin meal as compared with hydrolyzed cattle skin meal alone. 5. PER, NPR and NPU were also improved by the addition of the limiting amino acids. 6. Feed intake was not statistically significant upto 5% hydrolyzed cattle skin meal in the diet with was 100% replacement of hydrolyzed cattle skin meal with soybean meal and feather meal. Growth rate and feed conversion were not statistically significant at 3% but were significant 5% hydrolyzed cattle skin meal(p<0.05). These experiments were clearly indicated that hydrolyzed cattle skin meal could supplement in the diet upto 3% when mixed with 2 or 3 other protein sources.

퉁퉁마디로부터 염에 의하여 유도되는 Aldolase 유전자의 분리 및 발현분석

차준영,네티 엘마와티,김순길,이증주,임채오,정우식,이곤호,손대영 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Soil salinity is one of the most serious abiotic stresses limiting the productivity of agricultural crops. To cope with salt stress, plants respond with physiological, developmental and biochemical changes, including the synthesis of a number of proteins and the induction of gene expression. Salicornia herbacea is a halophytic plant that grows in salt marches and on muddy seashores. In order to understand the biochemical and molecular mechanisms of salt tolerance in S. herbacea, we isolated several genes that involved in the salt tolerance by mRNA differential display.Here we report the cloning of a cDNA encoding fructose-1, 6-bisphosphate aldolase, named ShADL, which is 1293 bp long and contains an open reading frame consisted of 359 amino acids with calculated molecular mass of 39 kDa. ShADL protein showed 86% identity with Arabidopsis and 78% with aldolase of common ice plant. Northern blot analysis revealed that the transcript of ShADL gene was increased dramatically depending on the NaCI concentrations.

공침법에 의한 BiDy₂Fe_(5)O_(12) 결정형 나노입자 분말의 제조 및 응용 연구

홍영대,조정환,김태엽,전성욱,홍영명 고신대학교 자연과학연구소 2007 고신대학교 자연과학연구소 논문집 Vol.14 No.-

금속산화물들은 각종 산업재료로서 유용하며 더욱이 그것들의 결정형 나노입자를 경제적으로 제조하는 기술은 21세기 첨단산업에 매우 중요하다. 저자들은 前報에서 화학합성법에 의한 각종 금속산화물의 나노입자를 제조하는 표준공정법을 연구하여 보고하였다. 본 연구에서는 그 표준공정법을 이용하여, 가넷의 일종인 BiDy_(2)Fe_(5)O_(12) 결정 나노입자 분말을 제조하고 그것의 자성체로의 응용을 위해 제품특성을 조사하었다. 가네트 제조과정에 필요한 침전물은 제품설계에 의거 몰비로 계산된 Bi, Dy, Fe의 질산염들의 혼합수용액에 침전제로서 pH NH_(3)-NH_(4)CI 완충용액 일정량을 가하여 얻어졌다. 이렇게 제조된 침전은 열처리과정을 거처 BiDy_(2)Fe_(5)O_(12) 결정형 나노입자 분말로 만들어졌다. 얻어진 제품의 입자크기, 조성, 결정구조 및 광자기성 등 특성시험이 SEM, ICP, XRD, 그리고 VSM 등을 사용하여 실시되었다. 각종 분석법을 사용하여 제품의 특성을 조사한 결과, 최초에 설계한 대로의 자성체가 나노 크기의 분말로 얻어졌으며 이것을 통하여 전보에서 확립한 표준공정법의 유효성도 입증되었다. Metallic oxides are useful as various industrial materials. Futhermore, the cost-effective techniques of fabricating the crystalline nanopartides of metallic oxides are very important for the high-tech industries of the 21 century, In the previous study, the authors reported the standard process for the preparation of crystalline nanoparticles of metallic oxides by chemical synthesis, In this study, BiDyzFesOiz nanoparticles were prepared by using the reported standard process and the characteristics of the product were investigated for applicability as magnetic substance. The precipitation needed for manufacturing process of garnet was made by adding the NH_(3)-NH_(4)CI buffer solution of pH 10 to the mixed solution of bismuth (III) nitrate, dysprosium(III) nitrate and iron(III) nitrate. The amount of each nitrate was calculated by the designed mole ratios. The nano-size crystalline powders of BiDy_(2)Fe_(5)O_(12) were earned by heating the precipitation at 800℃ for 4 hours in air. The characterizations, such as particle size, composition, crystal structure and magneto-optical property of garnet were tested by SEM, ICP, XRD, and VSM analyses. The results of the analyses showed the following two facts. First, a good magnetic substance of BiDy_(2)Fe_(5)O_(12) was earned as crystalline nano-size powders according to the original design. Next, the established standard process for the fabrication of METALLIC oxides nanonartieles was approved as a very effective method.

Carbamazepine이 만성 정신분열증 환자의 혈액, 간 기능에 미치는 영향

강대엽,김철응,김융희,한광수 용인정신의학연구소 1994 용인정신의학보 Vol.1 No.2