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Youping Xiao,Ying Chen,Yunbin Chen,Zhuangzhen He,Yiqi Yao,Jianji Pan 대한암학회 2019 Cancer Research and Treatment Vol.51 No.1
Purpose Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) was evaluated regarding its ability to preliminarily predict the short-term treatment response of nasopharyngeal carcinoma (NPC) following intensity-modulated radiation therapy. Materials and Methods IVIM-DWI with 14 b-factors (0-1,000 sec/mm2) was performed with a 3T MR system on 47 consecutive NPCs before, during (end of the 5th, 10th, 15th, 20th, and 25th fractions), and after fractional radiotherapy. IVIM parametrics (D, f, and D*) were calculated and compared to the baseline and xth fraction. Patients were categorized into responders and non-responders after radiotherapy. IVIM parametrics were also compared between subgroups. Results After fractional radiations, the D (except D5 and D at the end of the 5th fraction) after radiations were larger than the baseline D0 (p < 0.05), and the post-radiation D* (except D*5 and D*10) were smaller than D*0 (p < 0.05). f0 was smaller than f5 and f10 (p < 0.001) but larger than fend (p < 0.05). Furthermore, greater D5, D10, D15, and f10 coupled with smaller f0, D*20, and D*25were observed in responders than non-responders (all p < 0.01). Responders also presented larger D10, f10, D*20, and D*20 than non-responders (p < 0.05). Receiver operating characteristic curve analysis indicated that the D5, D*20, and f10 could better differentiate responders from non-responders. Conclusion IVIM-DWI could efficiently assess tumor treatment response to fractional radiotherapy and predict the radio-sensitivity for NPCs.
Annealing Effects on CuInS2 Thin Films Grown on Glass Substrates by Using Pulsed Laser Deposition
Lei Zhang,Jingang Fang,Mingkai Li,Xunzhong Shang,Yunbin He,강태원 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.3
CuInS2 thin films have been deposited on glass substrates at low temperature by using a self-madeceramic target and the pulsed laser deposition method. Polycrystalline and near-stoichiometricCuInS2 films with a band gap energy of 1.45 eV are obtained by post-annealing/sulfurization ata temperature of 500 C. X-ray diffraction reveals a highly (112) preferential orientation of theCuInS2 thin films while the Raman spectrum indicates the coexistence of a CuInS2 chalcopyritephase and CuAu orderings. A polymorphic transformation of metastable CuAu ordering into theequilibrium chalcopyrite structure takes place at a post-annealing temperature of 500 C with theCuxS phase being segregated at the surface. Further, the morphologies and the chemical statesof the films before and after annealing are characterized by atomic force microscopy and X-rayphotoelectron spectroscopy, respectively.