비전형 초음파 소견을 보이는 임신 9주에 진단된 자궁각임신

유애리 ( Ae Li Ryu ),김윤숙 ( Yun Sook Kim ),문성택 ( Seong Taek Mun ),전섭 ( Seob Jeon ),최승도 ( Seung Do Choi ),선우재근 ( Jae Gun Sunwoo ),배동한 ( Dong Han Bae ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.4

자궁각임신은 난관의 간질부에 착상이 일어나는 자궁외임신의 한 종류이다. 자궁각임신은 자궁외임신의 드문 형태로 임상적 소견은 난관임신과 유사하여 조기 진단이 어려운 경우가 많다. 모든 난관임신의 2~4%의 빈도를 차지하는 드문 질환이지만, 간질부의 풍부한 혈관 분포로 인하여, 파열될 경우 대량 출혈의 위험으로 인하여 산모의 이환율 및 사망률이 높은 질환이다. 자궁각임신에 의한 자궁파열은 주로 임신 8주에서 16주 사이에 일어나는 것으로 알려져 있다. 저자들 A cornual pregnancy occurs when the conceptus implants at the cornus of the uterus which is the junction between the fallopian tube and uterine cavity. Cornual pregnancy is a rare form of ectopic pregnancy and its diagnosis is difficult. It accounts for 2

노인들의 인지 증진 및 소근육 향상을 위한 보드도구 개발

이윤정(Yun-Jeong Lee),문서준(Seo-Jun Mun),손유림(You-Lim Son),임자운(Ja-Woon Lim),전현정(Hyun-Jeong Jeon),양영애(Yeong-Ae Yang) 대한고령친화산업학회 2023 대한고령친화산업학회지 Vol.15 No.2

연구목적 본 연구는 노인들의 인지 증진 및 소근육의 향상을 위한 보드도구를 개발하고, 대상자를 통해 사용성을 평가하고자 하였다. 연구방법 본 연구는 2022년 9월부터 10월까지 노인의 인지기능과 소근육 향상을 위한 바둑판 보드도구를 개발하였다. 지역사회에 거주하는 노인 10명에게 개발된 보드도구를 수행하게 한 후 사용성 평가를 시행하였고, 자유롭게 피드백을 제공할 수 있도록 인터뷰를 통해 질적자료를 수집⋅분석하였다. 사용된 연구도구는 SPSS version 27.0이며 대상자 일반적 특성 분석을 위한 기술통계와 사용성 평가에 대한 양적자료 빈도분석에 활용하였다. 연구결과 개발된 보드도구에 대한 사용성 평가 결과 안정성, 조작 및 기능성, 편의성, 만족도 4가지 항목에서 모두 높은 평가 점수와 매우 우수 등급(A)을 나타내었다. 대상자로부터 개발된 바둑판 보드도구에 대해 전반적으로 긍정적인 평가를 확인하였다. 결론 본 연구는 노인이 흥미와 재미를 느끼고 쉽게 접근할 수 있으며, 소근육 증진 및 인지기능을 향상할 수 있는 바둑판 보드도구를 개발하였다. 사용성 평가 결과를 바탕으로 개발된 보드도구의 문제점들을 보완한다면 노인들의 인지 기능 및 소근육 향상, 제품의 만족도가 더욱 높아질 것으로 기대된다. Objective : This study aimed to develop a board game tool for cognitive enhancement and improvement of fine motor skills in the elderly and to assess its usability among the participants. Methods : In this study, from September to October 2022, a board game was developed to improve the cognitive function and fine motor skills of the elderly. A usability test was conducted on 10 elderly people living in the community. For data analysis, SPSS version 27.0 was used, descriptive statistics were used to confirm the general characteristics of the subjects, and frequency analysis was conducted for usability evaluation. Results : The usability evaluation of the developed board game tool revealed high assessment scores and a “very excellent” grade (A) in all four categories: stability, control and functionality, usability, and satisfaction. Overall, the elderly participants provided positive assessments of the developed board game tool. Conclusion : This study has successfully developed a board game tool that the elderly can find interesting, enjoyable, and easy to access, while also promoting fine motor skills and cognitive enhancement. Based on the results of the usability evaluation, it is expected that addressing the identified issues in the developed board game tool will further enhance cognitive function and fine motor skills in the elderly and increase product satisfaction.

단일 신장의 요로결석에 의한 급성신부전증과 중복자궁에서의 자궁질유혈증

유애리 ( Ae Li Ryu ),김윤숙 ( Yun Sook Kim ),문성택 ( Seong Taek Mun ),전섭 ( Seob Jeon ),최승도 ( Seung Do Choi ),선우재근 ( Jae Gun Sunwoo ),배동한 ( Dong Han Bae ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.2

The unique clinical syndrome of the uterus didelphys, a unilateral partially or completely obstructed vagina, and ipsilateral renal agenesis is quite rare, and observed on the right side in greater frequency than on the left. The case of fifteen year old girl with uterus didelphys, unilateral partially obstructed vagina and acute renal failure associated with ureteral stone in unilateral kidney is described. Extracorporealshock wave lithotripsy (ESWL) and evacuation of the hematocolpos and excision of the vaginal septum were done. Aware of this relatively rare condition is mainstay of prompt diagnosis which will prevent permanent renal failure and unnecessary and destructive surgery.

Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression.

Min, Ae-Kyung,Bae, Kwi-Hyun,Jung, Yun-A,Choi, Yeon-Kyung,Kim, Mi-Jin,Kim, Ji-Hyun,Jeon, Jae-Han,Kim, Jung-Guk,Lee, In-Kyu,Park, Keun-Gyu The Endocrine Society 2014 Endocrinology Vol.155 No.8

<P>The fasting-induced hepatic hormone, fibroblast growth factor 21 (FGF21), is a potential candidate for the treatment of metabolic syndromes. Although peroxisome proliferator-activated receptor (PPAR)α is known to play a major role in the induction of hepatic FGF21 expression, other fasting-induced transcription factors that induce FGF21 expression have not yet been fully studied. In the present study, we investigated whether the fasting-induced activation of the orphan nuclear receptor Nur77 increases hepatic FGF21 expression. We found that fasting induced hepatic Nur77 and FGF21 expression. Glucagon and forskolin increased Nur77 and FGF21 expression in vivo and in vitro, respectively, and adenovirus-mediated overexpression of Nur77 (Ad-Nur77) increased FGF21 expression in vitro and in vivo. Moreover, knockdown of endogenous Nur77 expression by siRNA-Nur77 abolished the effect of forskolin on FGF21 expression. The results of ChIP assays, EMSA, and mutagenesis analysis showed that Nur77 bound to the putative NBRE of the FGF21 promoter in cultured hepatocytes and fasting induced Nur77 binding to the FGF21 promoter in vivo. Knockdown of PPARα partially inhibited forskolin-induced FGF21 expression, suggesting PPARα involvement in glucagon-stimulated FGF21 expression. In addition, double knockdown of PPARα and Nur77 further diminished FGF21 expression in cultured hepatocytes. In conclusion, this study shows that Nur77 mediates fasting-induced hepatic FGF21 expression, and suggests an alternative mechanism via which hepatic FGF21 transcription is mediated under fasting conditions.</P>

Mobile Applications for Managing Metabolic Syndrome

Eunjoo Jeon,Hyeoun-Ae Park,Soo jung Jo,Hannah Kang,Joo Yun Lee 한국간호과학회 2015 한국간호과학회 학술대회 Vol.2015 No.10

여성노인의 헤어스타일 행동과 헤어만족

박연희 ( Yun Hee Park ),전정애 ( Jeong Ae Jeon ),전선복 ( Seon Bok Jeon ) 한국미용학회 2012 한국미용학회지 Vol.18 No.6

According to an analysis on differences in aged women`s hairstyle behaviors and hair satisfaction, the following results have been obtained. First, aged women prefer going to a beauty shop to get beauty services. They liked a short hairstyle. When asked about current hairstyles, ``short cut`` was the most responded, followed by ``perm.`` In terms of use cycle, ``45 days`` was most common. When asked about who was influential in current hairstyles, most respondents said, ``my own decision.`` When asked what hair care products they use, ``just shampoo and hair rinse`` was mostly answered. Second, a significant difference was found in the location of hairstyle setting, preferred hairstyle, use cycle, current hairstyle and hair care depending on socio-demographic characteristics. Third, a significant difference was observed in hair satisfaction depending on how they obtain money to cover the cost of living, economic standards, current pocket money, location of hairstyle setting and hair care method. It would be a good idea for beauty shops to use the results of this study as basic data for customer management and customer satisfaction. In terms of beauty services, the results would be useful in providing systematic beauty services to aged women.

Genedia HCV ELISA 3.0, Rapid 및 Confirm 4.0 시약의 진단적 유용성 평가

임영애,전희선,곽연식,조영식,이동순 대한임상병리학회 1998 대한임상병리학회지 Vol.18 No.2

Association of CFTR gene variants with nontuberculous mycobacterial lung disease in a Korean population with a low prevalence of cystic fibrosis.

Jang, Mi-Ae,Kim, Su-Young,Jeong, Byeong-Ho,Park, Hye Yun,Jeon, Kyeongman,Kim, Jong-Won,Ki, Chang-Seok,Koh, Won-Jung Springer-Verlag 2013 Journal of human genetics Vol.58 No.5

<P>Several lines of evidence suggest that in Caucasian populations, mutations in the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene are associated with susceptibility to lung disease caused by nontuberculous mycobacteria (NTM). However, there is little data available in Asian populations, in which the prevalence of CF is very low. Therefore, we investigated this potential relationship in a Korean population. Sixty patients who fulfilled the diagnostic criteria for NTM lung disease were screened for genetic alterations in the CFTR gene by whole-exon resequencing. For all identified CFTR gene variants, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) genotyping was performed. Genotype and haplotype data were compared between 360 patients with NTM lung disease and 446 healthy controls. Among 13 CFTR genetic variants that were found by whole-exon resequencing, Q1352H showed a significantly higher frequency in NTM patients than in controls, giving an odds ratio (OR) of 4.27 (95% confidence interval (CI), 1.43-12.78). A haplotype with Q1352H showed the strongest association with the disease, with an OR of 3.73 (95% CI, 1.50-9.25). Furthermore, all Q1352H alleles were associated with the V allele of the V470M variant. Our results suggest that CFTR gene variants may increase susceptibility to NTM lung disease in the Korean population. Q1352H appears to be strongly related to NTM lung disease susceptibility in the Korean population.</P>

근층내 자궁근종이 체외수정시술의 결과에 미치는 영향

이애현 ( Lee Ae Hyeon ),김병윤 ( Kim Byeong Yun ),정근오 ( Jeong Geun O ),박기상 ( Park Gi Sang ),김성엽 ( Kim Seong Yeob ),이택후 ( Lee Taeg Hu ),전상식 ( Jeon Sang Sig ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.5

목적 : 본 연구는 정상자궁내강을 가진 근층내 근종이 체외수정시술의 결과에 미치는 영향을 알아보고자 하였다. 또한 이들 결과를 통하여 체외수정시술 전 내과적 보존적 치료나 근종절제술이 선행되어야 하는지를 파악하고자 하였다. 연구 방법 : 경북대학교병원 산부인과 불임클리닉에서 1999년 1월부터 2002년 12월까지 체외수정시술을 받은 불임환자 300명을 대상으로 근층내 자궁근종이 있는 군 (97명)과 근종이 없는 군 (203명)으로 나누어 연구하였다. 대상군의 설정에 있어 7 cm 이상의 거대 근종이나 근층내에 근종이 있더라도 자궁내강의 변형을 동반하는 경우는 대상에서 제외시켰다. 결과 : 근층내 자궁근종의 유무에 따른 체외수정시술의 결과를 비교할 때 임신율과 착상율은 두 군 사이에서 통계학적으로 유의한 차이를 보이지 않았다 (p>0.05). 또한 근층내 자궁근종이 있는 군에서 근종의 개수 및 해부학적 위치에 따른 임신율 비교에 있어 통계학적 유의성은 없었다 (p>0.05). 결론 : 자궁내강의 변형을 동반하지 않는 위치에 따른 차이도 임신율에 영향을 주지 않는 것으로 생각된다. 그러므로 정상 자궁내강을 가진 근층내 자궁근종이 있는 불임환자의 경우 체외수정시술 전에 내과적 치료나 근종절제술이 필요하지 않다는 결론에 도달할 수 있다. Objective : The aim of this study was to assess the effect of intramural uterine myoma in patients with a normal endometrial cavity on IVF-ET cycle outcome. This study was also investigated to find out whether medical supression or myomectomy needs to precede to IVF-ET. Methods : The subjects were 300 infertile patients who got IVF-ET from January 1999 to December 2002 at the Department of Obstetrics and Gynecology in Kyungpook National University Hospital, and they were divided into myoma group if 97 patients and non-myoma group of 203 ones. This study group did not include patients found to have large myoma (≥7 cm), or myoma distorting the uterine cavity. Results : Compared with the results of IVF-EF according to the presence of intramural uterine myoma, pregnancy rate and implantation rate between two groups had no statistically significant differences (p>0.05). Further comparisons within the myoma group showed no difference in pregnancy rate by number of myomas or site of myomas (p>0.05). Conclusion : Intramural uterine myoma not distorting the uterine cavity is considered to have no effect on the outcome of IVF-ET and no difference in the pregnancy rate according to the number of myomas or site of myomas. Therefore, these findings suggest that medical treatments or myomectomy before IVF-ET is not necessary to those infertile patients with intramural uterine myomas not distorting the uterine cavity.

지르코니아 임플란트 지대주의 기계적 강도에 관한 연구

신성애(Sung-ae Shin),김창섭(Chang-Seop Kim),조욱(Wook Cho),정창모(Chang-Mo Jeong),전영찬(Young-Chan Jeon),윤지훈(Ji-Hoon Yun) 대한턱관절교합학회 2009 구강회복응용과학지 Vol.25 No.4