정상인의 입각기에서 발바닥압력측정시 압력중심점의 위치

허재균,박시복,이상건,이강목,김영호,양길태,장윤희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

40ㆍ50대 일부 남성근로자의 골감소증 및 골다공증 유병실태와 위험요인

장윤균,서현주,진영우,정미선,성숙희,박두용,김종순,김수근 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 최근 국내에서도 골다공증과 관련된 생활양식의 규명에 관한 연구가 이루어지고 있으나, 아직까지 남성 골다공증에 대한 연구가 활발하게 이루어지지 않아 40, 50대 남성근로자를 대상으로 유병률을 파악하고, 골감소증 및 골다공증 관련 위험요인을 확인하고자 하였다. 방법: 원자력발전소에 근무하는 40, 50대 남성 근로자 2,073명을 대상으로 2004년 3월~7월 기간동안 생활습관을 파악하기 위하여 자기기입식 전산입력 방식으로 최종학력, 흡연여부, 음주여부, 신체활동 횟수를 조사하였고, 골밀도검사, 체성분검사(체지방률, 허리-엉덩이둘레비), 신체계측(신장, 체중)을 시행하였고, 골밀도 검사는 Osteosys사의 EXE-3000을 이용하여 종골부위를 측정하였고, 체지방률, 허리-엉덩이 둘레비는 Biospace사의 Inbody 3.0을 이용하여 측정하였다. 통계분석은 골감소증 및 골다공증의 관련요인을 분석하기 위해 다중로지스틱회귀분석을 시행하였다. 결과: 연구대상자의 골감소증 및 골다공증 유병률은 22.8%와 3.0%이었으며, 골감소증 및 골다공증의 관련요인으로는 연령이 증가할수록, 흡연자이거나 과거흡연자일 경우, 체질량지수가 25 kg/m^(2) 미만일 경우, 30분 이상 신체활동 횟수가 주 3회 미만일 경우가 유의한 연관성이 있었다. 결론: 성인 남성 40, 50대의 골감소증 및 골다공증의 유병률이 높은 편이었으며, 골감소증 및 골다공증으로 이환을 예방하기 위하여 금연, 활발한 신체활동을 촉진하여 골밀도를 개선시키는 생활습관으로의 변화를 권고해야 할 것이다. Objective: This study was conducted to investigate the prevalence and risk factors of osteopenia and osteoporosis in 40-59 year-old male workers working at nuclear power plants. Methods: Bone density, body composition, and anthropometry data were analyzed for 2,073 subjects were carried out from March 2004 to July, 2004. Educational level, smoking status, drinking status and frequency of physical activity were investigated by self-reported questionnaires through internet to identify lifestyles related to bone mass density. Bone mass density was measured by EXE-3000 of Osteosys Co. And body fat percentage, and waist-to-hip ratio by inbody 3.0 of Biospace Co. Results: The prevalence of ostepeniaosteopenia and osteoporosis was 22.8% and 3.0%, respectively. According to multinominal multinomial logistic regression analysis, age, smoking status (current smoker and former smoker), low body mass index (< 25kg/m^(2)), and frequency of physical activity were significantly associated with osteopenia and osteoporosis. Conclusions: The prevalence of ostcopenia and osteoporosis wasseemed high for the, when it was inferred from subjects' age compared to the results of previous studies. The This study results suggeststhat it is necessary for 40-59 year-old male workers to stop smoking, and exercise regularly in order to prevent osteopenia and osteoporosis.

한약재로부터 대장균 O-157에 대한 항균물질의 검색

김윤진,최원균,조재선 경희대학교 생명자원과학연구원 1998 硏究論文集 Vol.19 No.-

한약 처방 76종과 58종의 약재로 각 균주에 대한 항미생물 활성을 디스크 확산법으로 검색한 겨로가 처방에서는 삼소음과 주중황연탕이, 한약재에서는 소목과 황연이 열수와 메탄올 추출물이 모든 균주에 대해 항균 활성이 강한 것으로 검색되었다. 한약처방 76종에서 각 균주에 대해 항균활성이 강한 삼소음과 주증황연탕 추출물의 최소억제농도 실험 결과 삼소음 메탄올 추출물의 최소억제농도는 S. aureus 균주가 0.07 ㎎/㎖로 가장 낮게 나타났고, S. sonnel, S. flexnery, S. typhi는 0.31 ㎎/㎖를 나타냈으며, E. coli O157(V1+V2)와 E. coli O-157(none)에서는 각각 2.5 ㎎/㎖, 1.25 ㎎/㎖로 나타냈다. 주증황연탕 추출물의 최소억제농도는 S. aureus에서 0.01 ㎎/㎖로 가장 낮게 나타났으며, S. sonnei, S. flexnery, S. typhi에서는 각각 0.15 ㎎/㎖, 0.07 ㎎/㎖, 0.31 ㎎/㎖를 보였으며, E. coli O-157(V1+V2)과 E. coli O-157(none)은 5.0 ㎎/㎖를 나타냈다. 장내 세균에 대한 58종의 최소억제농도 실험 결과 이중 가장 높은 항균 활성을 타나낸 것은 소목 추출물로 최소억제농도는 E. coli O157(V1+V2)와 E. coli O157(none)에서 1.25 ㎎/㎖, S. aureus와 S. flexnery에서는 각각 0.39 ㎎/㎖, 0.078 ㎎/㎖를 보였으며, S. sonnei와 S. typhi는 0.15 ㎎/㎖를 나타내었다. This study was conducted for screening of antimicrobial compounds from 76 tradihonal prescriptions and 58 medicmal herbs. Among the prescriptions methanol and hot water extracts of Samsou˘m, Chujunghwang-yon'tang, and Sashinhwan showed antimicrobial activity against E. coli and Chujunghwang-yont'ang showed the highest antimicrobial activity. Among the medicmal herbs, hot water and methanol extracts of Terminalia chebula, Caesalpinia Sappan, and Coptis chiriensis showed the highest antimicrobial activity against E. coli 0157, Staphylococcus nureus, Shigella flexnery, Shigella. sonnet, Salmonella. typhi. Prescription such as Samsou˘m, Chujunghwang-yont'ang, and Sashinhwan were also interesting because both methanol and water extracts were active. Chujunghwang-yont'ang showed the most strong antimicrobial activies for the microoganisms tested. Water and methanol extracts of Terminalla chebuln, Caesalpinia Sappan, and Coptis chmensu showed the highest mhibitory effects on the growth of all bacteria tested.

흰쥐에서 음경발기 평가의 척도로서 음경해면체내압측정술 확립

송윤섭,김용준,이광우,김준모,문기혁,박영호,민영기,유형균,김형건 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Purpose: Because studies about the control of penile erection at the entral nervous system was dependent on the animal experiments, establishment of measuring penile erection is important to evaluate the effects changes at the central nervous system on the penile erection. Intracavernous pressure measurement in rats has been introduced as a suitable index for the evaluation of penile erection but this method is invasive and technically difficult. So, we established the intracavernous pressure measurement in rats as the experimental index for penile erection. Materials and Methods: 42 male adult Sprague-Dawley rats (250-300gm) were divided to saline or papaverine treated group. Rats were placed on a heating table to maintain their body temparature and anesthetized with 50mg/kg of pentobarbital sodium by intraperitoneal injection. A cannula was inserted to the left carotid artery to measure systemic blood pressure. Saline (0.05, 0.1ml), papaverine(0.05, 0.1, 0.25, 0.5, 1.0, 2.0mg) were injected intracavernously via 26 guage needle filled with saline or papaverine which connected to pressure transducer and polygraph was inserted into the corpus cavernosum on one side to inject the drug and to measure intracavernous presure. Results: Properly executed insertion and intracavernous administration produced a instantaneous but transient rise in intracavernous pressure that substantially stabilized and maintained at 5.4±0.4mmHg. Intracavernous pressure and duration of penile blood flow following intracavernous injection of papaverine are increased comared to those of saline. Conclusions: Monitoring intracavernous pressure in rats represents a suitable index for the evaluation of penile erection in small laboratory animals.

편광현미경에 의한 형태와 구성성분에 의한 토양의 비교분석에 관한연구(Ⅱ)

김은호,김재균,김명덕,신윤열,장성길,박성우,김영만 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

폐결핵치료 중인 환자에서 Rifampicin에 의해 유발된 위막성 대장염 2예

김봉진,권균홍,임창섭,김자영,홍정범,옥미선,배용목,김지연 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Pseudomembranous colitis (PMC) is a disease caused by Clostridium difficile proliferation. The causative drugs are clindamycin, third-generation cephalosporins, flouroquinolone and so on. Rifampicin has been reported as a cause of PMC in the 1980s, and the frequency of PMC is increasing because rifampicin is a first line drug for anti-tuberculosis therapy. Two patients were recently admitted to our hospital due to watery diarrhea for 1 month and they were diagnosed with PMC by sigmoidoscopy. Their onset age were 74, 72 years old and latent period of symptoms were 60, 129 days, respectively. In one case, the patient displayed coexisting hypertension and diabetes. The clinical symptoms improved after discontinuing the rifampicin and then administering oral metronidazole. We report here on two cases presumed to be rifampicin-induced PMC.

반송용 선형 유도 전동기의 급속 제동특성에 관한 연구

우정인,조윤현,노태균,신동률,이채동 東亞大學校 1996 東亞論叢 Vol.33 No.-

The SLIM used in the conveyance system has been generally developed the controller based on the slip frequency control and the VVVF method to obtain the quirk response for the position control signal. This paper deals with the trust control of the SLIM by vector control with Bang-Bang condition. Also, the control system is composed of the Pl controller for soft start of the SLIM and the q-axis current controller for correction in phase with Space Vector for reducing the harmonic pulsation in low speed. The processing for vector control and robust dynamic breaking control is carried out by MC80196KC micro processor and IGBT module. The proposed scheme is verified through the computer simulation and experiments for the 10KW SLIM.

내시경역행성담췌관조영술 후 발생한 종격동기종, 피하공기증, 긴장성 기흉 1예

조용건,이현승,권균홍,김자영,김봉진,김지연,배용목,박선자 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

However, Endoscopic retrograde cholangiopancreatography (ERCP) is still helpful procedure for the diagonosis of the pancreatobiliary disease and treatment through endoscopic sphinterectomy (EST) is relatively safe, these have possiblity of complications such as hemorrhage, infection, panceatitis, and perforation. ERCP related perforation was rarely reported in 0.3 to 1.1% of previous study, but most serious complication. A report of Pneumomediastinum, Tension Pneumothorax complicating perforation after ERCP and EST is very uncommon. In our hospital, we experienced case of pneumomediastinum, subcutaneous emphysema, and tension pneumothorax after ERCP and EST, and the patient (a 58 years old female with suspicious common bile duct stone) was treated successfully with conservative treatment.

수박 덩굴마름병 저항성 판별을 위한 SNP 표지인자 탐색

이혜은,홍종필,서혜영,허윤찬,안율균,김진희,김도선 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

:Watermelon (Citrullus lanatus) is an important vegetable crop in the world and contains various health promoting compounds including many antioxidants such as lycopene and beta-carotene. Genetic diversity of cultivated watermelon is very narrow, which is one of major factors limiting the improvement of watermelon breeding program. Gummy stem blight (Didymella bryoniae (Auersw.)) is one of the most destructive diseases and causes crown blight, defoliation and fruit rot, resulting in severe production loss in watermelon. Single nucleotide polymorphisms (SNPs), important molecular markers for genetic studies are frequent sequence variation in the plant genome. This study was performed to develop SNP markers related to gummy stem blight resistance from three watermelon lines, one susceptible and two resistant to gummy stem blight. Of them, 22 SNP primers which were sequence information on SNPs derived from comparing a resistant and susceptible line was used for high resolution melt analysis. A total of 14 candidate SNP primers were detected melt temperature difference. These SNP primers can be useful for developing disease resistance-related markers and, therefore, beneficial to watermelon breeding program.

Bifunctionalization of Isoprene: 1, 2 vs 1, 4-Regioselectivity on the Electrophilic Addition to Isoprene

Yun, In-Kyun,Koo, Sang-Ho 명지대학교 자연과학연구소 1996 자연과학논문집 Vol.13 No.-

Regioselective bromohydrin synthesis from isoprene has been studied in various solvents with NBS as an electrophile and water or actic acid as a nucleophile. The combination of a hot nucleophile (water) and a polar solvent (water or DMSO) tends to give exclusive formation of the 1, 2-bromohydrin. On the other hand, a soft nucleophile (acetic acid) prefers to five more of the 1, 4-bromohydrin in a less polar solvent.