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산야초 추출물을 함유한 식사 대용식을 이용한 초저열량 식사요법이 성인 비만 여성들의 체중감량과 건강 개선에 미치는 영향
장유경(Yukyung Chang),김지영(Jiyoung Kim),김상연(Sangyeon Kim),최형석(Hyeongsuk Choi),최승(Sung Choi),박미현(Mihyeon Park),홍성길(Seonggil Hong),이무영(Moo-Young Lee),황성주(Sungjoo Hwang) 한국식품영양과학회 2005 한국식품영양과학회지 Vol.34 No.1
본 연구는 산야초 추출물이 함유된 식사대용식을 이용한 초저열량 식사요법의 체중감량과 건강개선에 미치는 효과를 평가하고자 실시되었다. 그 결과 식사대용식을 이용하여 초저열량 식사요법을 한 성인 비만여성들의 경우 일반 음식으로만 초저열량 식사요법을 한 성인 비만여성들보다 체중과 체지방율이 유의하게 감소하였음을 알 수 있었다. 건강관련 인자는 두 군간에 유의한 차이는 없었으나 산야초 추출물이 함유된 식사대용식을 섭취한 군내에서 식사중재 기간 동안 유의하게 지질 개선 효과가 있었다. 한편, 산야초 추출물이 함유된 식사대용식의 맛에 대한 기호도도 긍정적으로 평가되었다. 그러므로, 본 연구에서 사용된 산야초 추출물을 주성분으로 하여 제조된 식사대용식은 향후 임상에서 비만치료제로 응용함에 있어 크게 도움이 될 것으로 사료된다. 단, 앞으로 요요 현상의 가능성에 대한 보다 장기간에 걸친 임상연구가 이루어져야 할 것으로 사료된다. This study was performed to investigate the effects of very low calorie diet (VLCD) using meal replacements that contain the wild grass extracts that are consisted of mainly Samul-tang ingredients on weight reduction and health promotion in the obese women (BMI≥25㎏/㎡) for four weeks. Fifty six premenopausal women participated in this experiment. Each subject was either classified as part of the control group (C group, n=28) that consumed 3 regular meals a day or the meal replacement group (MR group, n=28) that consumed 1 regular meal and 2 meal replacements within 600 kcal/day. Anthropometric measurements, body composition, health related factors, and psychological factors were assessed before (the initial) and after (the 4^(th) week) the study. Obesity was significantly decreased after the diet intervention. Anthropometric measurements such as weight, waist and hip circumference, and BMI and body composition such as body fat, and fat mass were significantly decreased in all groups after the diet intervention. Anthropometric measurements and body composition of the MR group were significantly decreased more than those of the C group. Serum total cholesterol was significantly decreased in the MR groups but not in the C group and serum triglyceride concentration was significantly decreased in all groups after the diet intervention. All the biochemical measurements were within normal ranges after the diet intervention. Psychological factors such as stress and depression were significantly decreased in two groups after the diet intervention. Therefore, VLCD using meal replacements is very effective for weight reduction in the obese premenopausal women.
지역 의료불평등 해소를 위한 미충족 의료지표 활용의 비판적 분석
박유경 ( Yukyung Park ),김진환 ( Jin-hwan Kim ),김선 ( Sun Kim ),김창엽 ( Chang-yup Kim ),한주성 ( Joo-sung Han ),김새롬 ( Saerom Kim ) 한국보건행정학회 2020 보건행정학회지 Vol.30 No.1
Background: Unmet healthcare needs have many advantages for measuring inequalities in healthcare use. However, the existing indicator is difficult to capture the reality of unmet healthcare needs sufficiently and is not quite appropriate in comparing regional inequality. The purpose of this study is to critically analyze the utilization of the unmet healthcare need indicator for regional healthcare inequalities research. Methods: We used the level of healthcare accessibility and healthcare need to categorize the regions that are known to cause differences in healthcare utilization between regions and verified how existing unmet healthcare need indicator is distributed at the regional level. Results: Four types of regions were classified according to the high and low levels of healthcare needs and accessibility. The hypothesis about the regional type expected to have the highest unmet healthcare need was not proved. The hypothesis about the lowest expected regional type was proved, but the difference in the average rate of unmet healthcare needs among regional types was not significant. The standard deviation of the rate of unmet healthcare needs among regions within the same type was also higher than the overall regional variation, which also disproved the whole frame of hypothesis. Conclusion: Failure to prove the hypothesis means the gap between the supposed meaning of the indicator and the reality. In order to understand the current state of healthcare utilization of people in various regions of Korea and to resolve inequality, fundamental research on the in-depth structure and mechanisms of healthcare utilization is needed.
Public Participation in the Process of Local Public Health Policy, Using Policy Network Analysis
Park, Yukyung,Kim, Chang-Yup,You, Myoung Soon,Lee, Kun Sei,Park, Eunyoung The Korean Society for Preventive Medicine 2014 예방의학회지 Vol.47 No.6
Objectives: To assess the current public participation in-local health policy and its implications through the analysis of policy networks in health center programs. Methods: We examined the decision-making process in sub-health center installations and the implementation process in metabolic syndrome management program cases in two districts ('gu's) of Seoul. Participants of the policy network were selected by the snowballing method and completed self-administered questionnaires. Actors, the interactions among actors, and the characteristics of the network were analyzed by Netminer. Results: The results showed that the public is not yet actively participating in the local public health policy processes of decision-making and implementation. In the decision-making process, most of the network actors were in the public sector, while the private sector was a minor actor and participated in only a limited number of issues after the major decisions were made. In the implementation process, the program was led by the health center, while other actors participated passively. Conclusions: Public participation in Korean public health policy is not yet well activated. Preliminary discussions with various stakeholders, including civil society, are needed before making important local public health policy decisions. In addition, efforts to include local institutions and residents in the implementation process with the public officials are necessary to improve the situation.
Jang, Insu,Chang, Hyeshik,Jun, Yukyung,Park, Seongjin,Yang, Jin Ok,Lee, Byungwook,Kim, Wankyu,Kim, V. Narry,Lee, Sanghyuk Oxford University Press 2015 Bioinformatics Vol.31 No.4
<P><B>Summary:</B> Deep sequencing of small RNAs has become a routine process in recent years, but no dedicated viewer is as yet available to explore the sequence features simultaneously along with secondary structure and gene expression of microRNA (miRNA). We present a highly interactive application that visualizes the sequence alignment, secondary structure and normalized read counts in synchronous multipanel windows. This helps users to easily examine the relationships between the structure of precursor and the sequences and abundance of final products and thereby will facilitate the studies on miRNA biogenesis and regulation. The project manager handles multiple samples of multiple groups. The read alignment is imported in BAM file format. Implemented features comprise sorting, zooming, highlighting, editing, filtering, saving, exporting, etc. Currently, miRseqViewer supports 84 organisms whose annotation is available at miRBase.</P><P><B>Availability and implementation:</B> miRseqViewer, implemented in Java, is available at https://github.com/insoo078/mirseqviewer or at http://msv.kobic.re.kr.</P><P><B>Contact:</B> sanghyuk@ewha.ac.kr</P>
이석화;장유경 한양대학교 2004 韓國 生活 科學 硏究 Vol.- No.24
OBJECTIVES: Quality of Life (QOL) is reduced and psychiatric morbidity is high in patients with irritable bowel syndrome (IBS) who visit referral centers. Little is known about difference and relationship between QOL and psychological factors in patients with IBS. This study aimed to explore these relationships. METHODS: We recruited 109 subjects from three different target groups: (1) consulters: 47 subjects were those who received treatment at the outpatient department of gastroenterology at the hospital; (2) non-consulters: 32 subjects were diagnosed as having IBS, but had not received medical health care; (3) controls: 30 subjects who had no IBS symptoms. The Rome II criteria, symptoms Checklist 90 Revised (SCL-90R), and a quality of life questionnaire (WHO-QOL BREF) were used to record the data. RESULTS: Consulters visited a physician mainly due to abdominal pain. There were significant differences in quality of life (overall QOL, physical health, psychological health, environmental health) and psychological factors (somatization, interpersonal-sensitivity) among the three groups. Overall QOL, physical health, and psychological health were significantly low in patients with IBS compared to controls. Somatization and anxiety of patients with IBS were significant lower than those of controls. Also, consulters showed significantly lower interpersonal-sensitivity than non-consulters. CONCLUSIONS: This study showed that QOL and psychological factors in the patients with IBS were negatively estimated compared to the controls. Our findings have implications for treatments and understanding of IBS.
식사대용식을 이용한 초저열량 식사요법이 20대 비만 여성들의 심리적 요인과 삶의 질에 미치는 효과
김지영(Kim Jiyoung),김상연(Kim Sangyeon),정경아(Jung Kyunga),장유경(Chang Yukyung),최형석(Choi Hyeongsuk),최승(Choi Sung),박미현(Park Mihyeon),홍성길(Hong Seonggil),황성주(Hwang Sungjo) 韓國營養學會 2007 Journal of Nutrition and Health Vol.40 No.7
This study was performed to investigate the effects of very low calorie diet (VLCD) using meal replacements that contain the wild grass extracts based on Samul-tang ingredients on psychological factors and quality of life in the obese women (BMI ≥ 25 ㎏/㎡) for four weeks. Seventy five women (20≤ age < 26) participated in this experiment. Subjects were randomly classified three groups: I) General diet group (GD group, n = 27) consumed 3 regular meals within 600 ㎉/day 2) Meal replacements group (MR group, n = 27) consumed 1 regular meal and 2 meal replacements within 600 ㎉/day 3) Herbal Meal replacements group (HMR group, n = 27) consumed 1 regular meal and 2 meal replacements within 600 kcal/day. Physical factors (weight, BMI, fat (%)) of the HMR group significantly decreased more than those of GD and MR groups. Moreover, binge eating habit and environmental factors (surrounding support, emotional reaction, expression of opinion) of the HMR group significantly decreased more than those of GD and MR groups. Psychological factor and quality of life were no significant differences among three groups during the experimental period, because both were significantly decreased in all groups after 4 weeks. Therefore, very low calorie diet using meal replacements that contain the wild grass extracts based on Samul-tang ingredients for 4 weeks was effective on improvement of psychological factor and quality of life as well as weight reduction in the obese preme-nopausal women.
Association Between Local Government Social Expenditures and Mortality Levels in Korea
Ko, Hansoo,Kim, Jinseob,Kim, Donggil,Kim, Saerom,Park, Yukyung,Kim, Chang-Yup The Korean Society for Preventive Medicine 2013 Journal of Preventive Medicine and Public Health Vol.46 No.1
Objectives: We examined the association between social expenditures of the local government and the mortality level in Korea, 2004 to 2010. Methods: We used social expenditure data of 230 local governments during 2004 to 2010 from the Social Expenditure Database prepared by the Korean Institute for Health and Social Affairs. Fixed effect panel data regression analysis was adopted to look for associations between social expenditures and age-standardized mortality and the premature death index. Results: Social expenditures of local governments per capita was not significantly associated with standardized mortality but was associated with the premature death index (decline of 1.0 [for males] and 0.5 [for females] for each expenditure of 100 000 Korean won, i.e., approximately 100 US dollar). As an index of the voluntary effort of local governments, the self-managed project ratio was associated with a decline in the standardized mortality in females (decline of 0.4 for each increase of 1%). The share of health care was not significant. Conclusions: There were associations between social expenditures of the local government and the mortality level in Korea. In particular, social expenditures per capita were significantly associated with a decline in premature death. However, the voluntary efforts of local governments were not significantly related to the decline in premature death.