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      • KCI등재

        Task Offloading Based on Edge Collaboration in MEC-Enabled IoV Networks

        Deng, Tao Yu,Chen, Yueyun,Chen, Guang,Yang, Meijie,Du, Liping 한국통신학회 2023 Journal of communications and networks Vol.25 No.2

        Benefiting from its abundant computing resourcesand low computing latency, mobile edge computing (MEC) isa promising approach for enhancing the computing capacity ofthe 5G Internet of vehicles (IoV). Because of the high mobility,handover is frequent and inevitable in IoV networks. In thispaper, we investigate an edge collaborative task offloading andsplitting strategy in MEC-enabled IoV networks, in which thetask is splitted on the edge and paralleling executed by eachpart of the task on several MEC servers when handover isoccured. Applications in IoV networks have flexible requirementson latency and energy consumption. To realize the tradeoffbetween latency and energy consumption, we formulate the taskoffloading and splitting as an optimization problem with the aimof minimizing the total cost of latency and energy consumptionby jointly optimizing the task splitting ratio and uplink transmitpower of vehicle terminal (VT). Because the proposed problemis non-smooth and non-convex, we divide the original probleminto two convex subproblems, and apply an alternate convexsearch (ACS) algorithm to obtain the optimized solution withlow computational complexity. Numerical simulation results showthat the proposed method can adjust the offloading strategyproperly according to task preference, and obtain a lower totalcost compared with the baseline algorithms.

      • KCI등재

        Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1

        Yu Deng,Wanjun Guo,Guancheng Li,Shuang Li,Hong Li,Xinyan Li,Bei Niu,Mingzhu Song,Yamei Zhang,Zhijian Xu,Fulun Li 한국유방암학회 2020 Journal of breast cancer Vol.23 No.1

        Purpose: C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor that is overexpressed in many cancers. CtBP1 transcriptionally represses a broad array of tumor suppressors, which promotes cancer cell proliferation, migration, invasion, and resistance to apoptosis. Recent studies have demonstrated that CtBP1 is a potential target for cancer therapy. This study was designed to screen for compounds that potentially target CtBP1. Methods: Using a structure-based virtual screening for CtBP1 inhibitors, we found protocatechuic aldehyde (PA), a natural compound found in the root of a traditional Chinese herb, Salvia miltiorrhiza, that directly binds to CtBP1. Microscale thermophoresis assay was performed to determine whether PA and CtBP1 directly bind to each other. Further, clustered regularly interspaced short palindromic repeats associated Cas9 nuclease-mediated CtBP1 knockout in breast cancer cells was used to validate the CtBP1 targeting specificity of PA. Results: Functional studies showed that PA repressed the proliferation and migration of breast cancer cells. Furthermore, PA elevated the expression of the downstream targets of CtBP1, p21 and E-cadherin, and decreased CtBP1 binding affinity for the promoter regions of p21 and E-cadherin in breast cancer cells. However, PA did not affect the expression of p21 and E-cadherin in the CtBP1 knockout breast cancer cells. In addition, the CtBP1 knockout breast cancer cells showed resistance to PA-induced repression of proliferation and migration. Conclusion: Our findings demonstrated that PA directly bound to CtBP1 and inhibited the growth and migration of breast cancer cells through CtBP1 inhibition. Structural modifications of PA are further required to enhance its binding affinity and selectivity for CtBP1.

      • KCI등재

        Attention Capsule Network for Aspect-Level Sentiment Classification

        ( Yu Deng ),( Hang Lei ),( Xiaoyu Li ),( Yiou Lin ),( Wangchi Cheng ),( Shan Yang ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.4

        As a fine-grained classification problem, aspect-level sentiment classification predicts the sentiment polarity for different aspects in context. To address this issue, researchers have widely used attention mechanisms to abstract the relationship between context and aspects. Still, it is difficult to effectively obtain a more profound semantic representation, and the strong correlation between local context features and the aspect-based sentiment is rarely considered. In this paper, a hybrid attention capsule network for aspect-level sentiment classification (ABASCap) was proposed. In this model, the multi-head self-attention was improved, and a context mask mechanism based on adjustable context window was proposed, so as to effectively obtain the internal association between aspects and context. Moreover, the dynamic routing algorithm and activation function in capsule network were optimized to meet the task requirements. Finally, sufficient experiments were conducted on three benchmark datasets in different domains. Compared with other baseline models, ABASCap achieved better classification results, and outperformed the state-of-the-art methods in this task after incorporating pre-training BERT.

      • 지능정보사회에서의 중국지역간 정보격차와 지각된 학업성과에 관한 연구

        YU DENG SHENG,ZHANG YUANYUAN,SONG ZHANMEI,임규건(Gyoo Gun Lim) 한국IT서비스학회 2019 한국IT서비스학회 학술대회 논문집 Vol.2019 No.2

        2000년대부터 중국 경제성장을 주도하는 핵심적 산업인 정보통신산업에 대해 집중적으로 육성 및 지원함으로써 정보통신기술의 사회적 확산도 매우 빠른 속도로 진전되었다. 그러나 정보통신 기술산업의 생산품과 개인 소득의 측면에서 지역 간의 경제성장이 빠른 지역과 그렇지 못한 지역간의 정보통신기술의 확산 속도 및 보급의 격차는 여전히 심한 것으로 나타났다. 또한 중국인터넷발전상황통계보고에 따르면 도시와 농촌의 인터넷 보급률을 살펴보면 보급률은 모두 증가세를 보이지만 격차는 여전히 큰 것으로 확인할 수 있다. 본 연구는 정보격차가 지각된 학업성과에 어떠한 영향을 미치는 지에 파악하고자 한다. 또한지역 간의 정보격차에 따른 지각된 학업성과의 차이가 존재하는 지에 확인하고자 한다. 향후 중국 지역 간의 정보격차를 해소할 수 있는 방안을 모색함으로써 교육성과를 제고하고 교육역량 활성화에 기여할 수 있는 것으로 기대된다.

      • KCI등재

        Growth of centimeter-scale perovskite single-crystalline thin film via surface engineering

        Deng Yu-Hao,Yang Zhen-Qian,Ma Ren-Min 나노기술연구협의회 2020 Nano Convergence Vol.7 No.25

        Modern electronic and photonic devices rely on single-crystalline thin film semiconductors for high performance and reproducibility. The emerging halide perovskites have extraordinary electronic and photonic properties and can be synthesized via low cost solution-based methods. They have been used in a variety of devices with performance approaching or over the devices based on conventional materials. However, their solution based growth method is intrinsically challenge to grow large scale single-crystalline thin film due to the random nucleation and isotropous growth of the crystal. Here, we report the growth of centimeter-scale perovskite single-crystalline thin films by con‑ trolling the nucleation density and growth rate of the crystal under a spatially confined growth condition. The hydro‑ phobic treatment on substrates inhibits nucleation and accelerates the growth of single-crystalline thin film, provid‑ ing enough space for initial nucleus growing up quickly without touching each other. Single-crystalline perovskite thin-film with an aspect ratio of 1000 (1 cm in side length, 10 μm in thickness) has been successfully grown. The low trap density and the high mobility of the as-grown thin film show a high crystallinity. The photodetector based on the perovskite thin film has achieved a gain ~ 10 4 , benefitting from the short transit time of the carries due to the high mobility and thin thickness of the active layer. Our work opens up a new route to grow large scale perovskite singlecrystalline thin films, providing a platform to develop high- performance devices.

      • The Data Processing and Remote Transmission Technologies for On-Line Monitoring Of Eurytopic Distributed

        Yu-rong Deng,Qiu-li Wu,Wei Zhang,Ze-cheng Lv 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.5

        Aiming at the provincial level within the grid wide-area distributed substation equipment on-line monitoring various types, processing of large amount of data and communication standard is not unified. Optimization of the structure of communication between the various levels, researched open communication format specification, established data interaction integration model. The paper studied the wide-area distributed on-line monitoring comprehensive processing unit of end stations with provincial level network of on-line monitoring system for the main platform of communication technology. Application shows that systems runs stability and meet online monitoring data collection, processing, transmission, and other functions, and has good maintainability and extensibility, adapt to various on-line monitoring in province level the development trend of the main platform for centralized management.

      • KCI등재

        Hsa-miRNA-143-3p Reverses Multidrug Resistance of Triple-Negative Breast Cancer by Inhibiting the Expression of Its Target Protein Cytokine-Induced Apoptosis Inhibitor 1 In Vivo

        Yu Wei Deng,Wen Jing Hao,Yi Wen Li,Yi Xin Li,Bo Chen Zhao,Dan Lu 한국유방암학회 2018 Journal of breast cancer Vol.21 No.3

        Purpose: Multidrug resistance (MDR) remains a major obstacle in the treatment of triple-negative breast cancer (TNBC) with conventional chemotherapeutic agents. A previous study demonstrated that hsa-miRNA-143-3p plays a vital role in drug resistance of TNBC. Downregulation of hsa-miRNA-143-3p upregulated the expression of its target protein cytokine-induced apoptosis inhibitor 1 (CIAPIN1) in order to activate MDR, while upregulation of hsa-miRNA-143-3p effectively enhances the sensitivity of drug-resistant TNBC cells to chemotherapeutics. The present study aimed to further verify these findings in vivo. Methods: We established a hypodermic tumor nude mice model using paclitaxel- resistant TNBC cells. We expressed ectopic hsa-miRNA- 143-3p under the control of a breast cancer-specific human mammaglobin promoter that guided the efficient expression of exogenous hsa-miRNA-143-3p only in breast cancer cells. Thereafter, we overexpressed hsa-miRNA-143-3p in xenografts using a recombinant virus system and quantified the expression of hsa-miRNA-143-3p, CIAPIN1 protein, and proteins encoded by related functional genes by western blot. Results: We successfully completed the prospective exploration of the intravenous virus injection pattern from extensive expression to targeted expression. The overexpression of hsa-miRNA-143-3p significantly alleviated chemoresistance of TNBC by inhibiting viability. In addition, we observed that the expression of CIAPIN1 as a hsa-miRNA-143-3p target protein was remarkably decreased. Conclusion: We partly illustrated the mechanism underlying the hsa-miRNA-143-3p/CIAPIN1 drug resistance pathway. HsamiRNA- 143-3p as a tumor suppressive microRNA may be a novel target to effectively reverse MDR of TNBC in vivo.

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