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RISS 인기검색어
- 검색키워드
- 저자 : Youqi Li (검색결과 3 건)
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Bo Li,Wenyi Lv,Chunde Li,Jiongxian Yang,Jiajia Chen,Jin Feng,Li Chen,Zhenyu Ma,Youqi Li,Jiayi Wang,Yanwei Liu,Yanong Li,Shuai Liu,Shiqi Luo,Xiaoguang Qiu 대한암학회 2020 Cancer Research and Treatment Vol.52 No.4
Purpose Whether craniospinal irradiation (CSI) could be replaced by limited-field radiation in non-metastatic bifocal germinoma remains controversial. We addressed the issue based on the data from our series and the literature. Materials and Methods Data from 49 patients diagnosed with non-metastatic bifocal germinoma at our hospital during the last 10 years were collected. The Pediatric Quality of Life Inventory 4.0 was used to evaluate health-related quality of life (HRQOL). Additionally, 81 patients identified from the literature were also analyzed independently. Results In our cohort, 34 patients had tumors in the sellar/suprasellar (S/SS) plus pineal gland (PG) regions and 15 in the S/SS plus basal ganglia/thalamus (BG/T) regions. The median follow-up period was 52 months (range, 10 to 134 months). Our survival analysis showed that patients treated with CSI (n=12) or whole-brain radiotherapy (WBRT; n=34) had comparable disease-free survival (DFS; p=0.540), but better DFS than those treated with focal radiotherapy (FR; n=3, p=0.016). All 81 patients from the literature had tumors in the S/SS+PG regions. Relapses were documented in 4/45 patients treated with FR, 2/17 treated with whole-ventricle irradiation, 0/4 treated with WBRT, and 1/15 treated with CSI. Survival analysis did not reveal DFS differences between the types of radiation field (p=0.785). HRQOL analysis (n=44) in our cohort found that, compared with S/SS+PG germinoma, patients with BG/T involvement had significantly lower scores in social and school domains. However, HRQOL difference between patients treated with CSI and those not treated with CSI was not significant. Conclusion In patients with non-metastatic bifocal germinoma, it is rational that CSI could be replaced by limited-field radiation. HRQOL in patients with BG/T involvement was poorer.
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Effect of high-energy neutron source on predicting the proton beam current in the ADS design
Youqi Zheng,Xunzhao Li,,Hongchun Wu 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.8
The accelerator-driven subcritical system (ADS) is driven by a neutron source from spallation reactionsintroduced by the injected proton beam. Part of the neutron source has energy as high as a few hundredMeV to a few GeV. The effects of high-energy source neutrons (En > 20 MeV) are usually approximated byenergy cut-off treatment in practical core calculations, which can overestimate the predicted protonbeam current in the ADS design. This article intends to quantize this effect and propose a way to solvethis problem. To evaluate the effects of high-energy neutrons in the subcritical core, two models areestablished aiming to cover the features of current experimental facilities and industrial-scale ADS in thefuture. The results show that high-energy neutrons with En > 20 MeV are of small fraction (2.6%) in theneutron source, but their contribution to the source efficiency is about 23% for the large scale ADS. Basedon this, a neutron source efficiency correction factor is proposed. Tests show that the new correctionmethod works well in the ADS calculation. This method can effectively improve the accuracy of theprediction of the proton beam current.
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Conceptual design of a MW heat pipe reactor
Wu Yunqin,Zheng Youqi,Chen Qichang,Li Jinming,Du Xianan,Wang Yongping,Tao Yushan 한국원자력학회 2024 Nuclear Engineering and Technology Vol.56 No.3
In recent years, unmanned underwater vehicles (UUV) have been vigorously developed, and with the continuous deepening of marine exploration, traditional energy can no longer meet the energy supply. Nuclear energy can achieve a huge and sustainable energy supply. The heat pipe reactor has no flow system and related auxiliary systems, and the supporting mechanical moving parts are greatly reduced, the noise is relatively small, and the system is simpler and more reliable. It is more favorable for the control of unmanned systems. The use of heat pipe reactors in unmanned underwater vehicles can meet the needs for highly compact, long-life, unmanned, highly reliable, ultra-quiet power supplies. In this paper, a heat pipe reactor scheme named UPR-S that can be applied to unmanned underwater vehicles is designed. The reactor core can provide 1 MW of thermal power, and it can operate at full power for 5 years. UPR-S has negative reactive feedback, it has inherent safety. The temperature and stress of the reactor are within the limits of the material, and the core safety can still be guaranteed when the two heat pipes are failed.
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